DK1328507T3 - Naphthylsalicylanilider som antimikrobielle og anti-inflammatoriske midler - Google Patents

Naphthylsalicylanilider som antimikrobielle og anti-inflammatoriske midler

Info

Publication number
DK1328507T3
DK1328507T3 DK01979927T DK01979927T DK1328507T3 DK 1328507 T3 DK1328507 T3 DK 1328507T3 DK 01979927 T DK01979927 T DK 01979927T DK 01979927 T DK01979927 T DK 01979927T DK 1328507 T3 DK1328507 T3 DK 1328507T3
Authority
DK
Denmark
Prior art keywords
substituted
naphthylsalicylanilides
alkyl
antimicrobial
substitution
Prior art date
Application number
DK01979927T
Other languages
Danish (da)
English (en)
Inventor
Robert A Coburn
Richard T Evans
Robert J Genco
Original Assignee
Univ New York State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York State Res Found filed Critical Univ New York State Res Found
Application granted granted Critical
Publication of DK1328507T3 publication Critical patent/DK1328507T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/60—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton at least one of the singly-bound nitrogen atoms being acylated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/84—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK01979927T 2000-10-02 2001-10-02 Naphthylsalicylanilider som antimikrobielle og anti-inflammatoriske midler DK1328507T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23731900P 2000-10-02 2000-10-02
PCT/US2001/042436 WO2002028819A1 (en) 2000-10-02 2001-10-02 Naphthylsalicylanilides as antimicrobial and antiinflammatory agents

Publications (1)

Publication Number Publication Date
DK1328507T3 true DK1328507T3 (da) 2007-07-02

Family

ID=22893236

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01979927T DK1328507T3 (da) 2000-10-02 2001-10-02 Naphthylsalicylanilider som antimikrobielle og anti-inflammatoriske midler

Country Status (11)

Country Link
US (1) US6407288B1 (ja)
EP (1) EP1328507B1 (ja)
JP (1) JP4086658B2 (ja)
CN (1) CN1249019C (ja)
AT (1) ATE356798T1 (ja)
AU (1) AU2002211842A1 (ja)
CA (1) CA2424396C (ja)
DE (1) DE60127285T2 (ja)
DK (1) DK1328507T3 (ja)
MX (1) MXPA03002891A (ja)
WO (1) WO2002028819A1 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7709026B2 (en) * 2001-10-29 2010-05-04 Columbia Laboratories, Inc. Low concentration of peroxide for treating or preventing vaginal infections
EA008622B1 (ru) * 2002-06-05 2007-06-29 Инститьют Оф Медисинал Молекьюлар Дизайн. Инк. Ингибиторы ассоциированной с иммунитетом протеинкиназы
TW200410671A (en) * 2002-06-05 2004-07-01 Inst Med Molecular Design Inc Medicines for inhibiting the activation of AP-1
KR101054562B1 (ko) * 2002-06-06 2011-08-04 가부시키가이샤 이야쿠 분지 셋케이 겐쿠쇼 항알레르기약
TW200307535A (en) * 2002-06-10 2003-12-16 Inst Med Molecular Design Inc Therapeutic agent for cancer
TW200410675A (en) * 2002-06-10 2004-07-01 Inst Med Molecular Design Inc An NF-κB activation inhibitor
EP1542699A4 (en) * 2002-07-15 2009-03-25 Myriad Genetics Inc COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF
JP2006511477A (ja) * 2002-09-18 2006-04-06 ザ プロクター アンド ギャンブル カンパニー 非ハロゲン化抗菌剤及びその製造方法
CN104546857B (zh) * 2013-10-18 2017-01-04 北京北科德源生物医药科技有限公司 化合物naphthoylenequinazolone的抗菌用途
US20190328687A1 (en) * 2014-11-17 2019-10-31 Victoria Link Limited Antibacterial Compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4287191A (en) * 1980-04-14 1981-09-01 The Research Foundation Of State University Of New York Novel salicylanilides and microbiocidal compositions and uses thereof
US4358443A (en) * 1980-04-14 1982-11-09 The Research Foundation Of State University Of New York Method and composition for controlling the growth of microorganisms
US4742083A (en) * 1983-08-24 1988-05-03 Lever Brothers Company Method of relieving pain and inflammatory conditions employing substituted salicylamides
US4939132A (en) * 1985-04-15 1990-07-03 The Research Foundation Of State University Of New York Novel 5-alkylsulfonylsalicylanilides and microbiocidal compositions for controlling the growth of microorganisms
US5958911A (en) * 1996-11-05 1999-09-28 The Research Foundation Of State University Of New York Method of relieving inflammation by using 5-alkylsulfonylsalicylanilides

Also Published As

Publication number Publication date
JP2004510756A (ja) 2004-04-08
CA2424396A1 (en) 2002-04-11
JP4086658B2 (ja) 2008-05-14
EP1328507A1 (en) 2003-07-23
CN1249019C (zh) 2006-04-05
US20020065322A1 (en) 2002-05-30
DE60127285D1 (de) 2007-04-26
EP1328507B1 (en) 2007-03-14
WO2002028819A1 (en) 2002-04-11
EP1328507A4 (en) 2005-07-27
CN1468210A (zh) 2004-01-14
ATE356798T1 (de) 2007-04-15
AU2002211842A1 (en) 2002-04-15
CA2424396C (en) 2009-12-08
MXPA03002891A (es) 2003-10-15
DE60127285T2 (de) 2007-12-20
US6407288B1 (en) 2002-06-18

Similar Documents

Publication Publication Date Title
DK0931788T3 (da) Metalloproteasehæmmere
ID28263A (id) DIPEPTIDA OKSAMIL TERMODIFIKASI C-TERMINAL SEBAGAI PENGHAMBAT PADA KELUARGA ICE-ced-3 DARI PROTEASE SISTEINA
GR3022340T3 (en) Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents.
DK1328507T3 (da) Naphthylsalicylanilider som antimikrobielle og anti-inflammatoriske midler
DK1392666T3 (da) Biologisk aktive methylenblåt-derivater
MY139244A (en) 2,3-dihydro-6-nitroimidazo [2,1-b] oxazole
SE0100902D0 (sv) Compounds
HK1096549A1 (en) Imidazopyridine-derivatives as inducible no-synthase inhibitors
SE0004245D0 (sv) Novel compounds and their use
DK0537622T3 (da) Et antifungalt middel, dets fremstilling og mikroorganismer dertil
EA200200673A1 (ru) Оксазолидиноновые эфиры бензойной кислоты, содержащие гидроксиацетилпиперазиновый заместитель
DE69121259D1 (de) Beta-Lactam-Verbindungen und ihre Herstellung
NO974588L (no) Triazol-antifungalt middel
NZ336091A (en) Aqueous disinfecting cleaning composition
ATE223226T1 (de) Azazyklohexapeptid-verbindungen
MY144554A (en) Pharmaceutical composition comprising 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole derivatives
ATE399169T1 (de) Imidazopyridinderivate als inhibitoren der induzierbaren no-synthase
ATE522501T1 (de) Phenolische verbindungen und diese enthaltende aufnahmematerialien
SE0003186D0 (sv) New process
ATE398617T1 (de) Imidazoä4,5-büpyridinderivate als inhibitoren der induzierbaren no-synthase
DK0713702T3 (da) Anxiolytisk middel
ATE214692T1 (de) Metalloproteinase-inhibitoren
AU2003248059A1 (en) NOVEL Alpha-KETOAMIDE DERIVATIVE AND USE THEREOF
DK1140932T3 (da) Derivater af benzo-1,8-naphtyridin
DK1119351T3 (da) Anvendelse af katecholderivater som proteinaseinhibitorer