AU2002211842A1 - Naphthylsalicylanilides as antimicrobial and antiinflammatory agents - Google Patents

Naphthylsalicylanilides as antimicrobial and antiinflammatory agents

Info

Publication number
AU2002211842A1
AU2002211842A1 AU2002211842A AU1184202A AU2002211842A1 AU 2002211842 A1 AU2002211842 A1 AU 2002211842A1 AU 2002211842 A AU2002211842 A AU 2002211842A AU 1184202 A AU1184202 A AU 1184202A AU 2002211842 A1 AU2002211842 A1 AU 2002211842A1
Authority
AU
Australia
Prior art keywords
substituted
naphthylsalicylanilides
alkyl
antiinflammatory agents
antimicrobial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002211842A
Other languages
English (en)
Inventor
Robert A. Coburn
Richard T. Evans
Robert J. Genco
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Foundation of State University of New York
Original Assignee
Research Foundation of State University of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Foundation of State University of New York filed Critical Research Foundation of State University of New York
Publication of AU2002211842A1 publication Critical patent/AU2002211842A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/60—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton at least one of the singly-bound nitrogen atoms being acylated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/84—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2002211842A 2000-10-02 2001-10-02 Naphthylsalicylanilides as antimicrobial and antiinflammatory agents Abandoned AU2002211842A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23731900P 2000-10-02 2000-10-02
US60237319 2000-10-02
PCT/US2001/042436 WO2002028819A1 (en) 2000-10-02 2001-10-02 Naphthylsalicylanilides as antimicrobial and antiinflammatory agents

Publications (1)

Publication Number Publication Date
AU2002211842A1 true AU2002211842A1 (en) 2002-04-15

Family

ID=22893236

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002211842A Abandoned AU2002211842A1 (en) 2000-10-02 2001-10-02 Naphthylsalicylanilides as antimicrobial and antiinflammatory agents

Country Status (11)

Country Link
US (1) US6407288B1 (ja)
EP (1) EP1328507B1 (ja)
JP (1) JP4086658B2 (ja)
CN (1) CN1249019C (ja)
AT (1) ATE356798T1 (ja)
AU (1) AU2002211842A1 (ja)
CA (1) CA2424396C (ja)
DE (1) DE60127285T2 (ja)
DK (1) DK1328507T3 (ja)
MX (1) MXPA03002891A (ja)
WO (1) WO2002028819A1 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7709026B2 (en) * 2001-10-29 2010-05-04 Columbia Laboratories, Inc. Low concentration of peroxide for treating or preventing vaginal infections
EA008622B1 (ru) * 2002-06-05 2007-06-29 Инститьют Оф Медисинал Молекьюлар Дизайн. Инк. Ингибиторы ассоциированной с иммунитетом протеинкиназы
TW200410671A (en) * 2002-06-05 2004-07-01 Inst Med Molecular Design Inc Medicines for inhibiting the activation of AP-1
KR101054562B1 (ko) * 2002-06-06 2011-08-04 가부시키가이샤 이야쿠 분지 셋케이 겐쿠쇼 항알레르기약
TW200307535A (en) * 2002-06-10 2003-12-16 Inst Med Molecular Design Inc Therapeutic agent for cancer
TW200410675A (en) * 2002-06-10 2004-07-01 Inst Med Molecular Design Inc An NF-κB activation inhibitor
EP1542699A4 (en) * 2002-07-15 2009-03-25 Myriad Genetics Inc COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF
JP2006511477A (ja) * 2002-09-18 2006-04-06 ザ プロクター アンド ギャンブル カンパニー 非ハロゲン化抗菌剤及びその製造方法
CN104546857B (zh) * 2013-10-18 2017-01-04 北京北科德源生物医药科技有限公司 化合物naphthoylenequinazolone的抗菌用途
US20190328687A1 (en) * 2014-11-17 2019-10-31 Victoria Link Limited Antibacterial Compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4287191A (en) * 1980-04-14 1981-09-01 The Research Foundation Of State University Of New York Novel salicylanilides and microbiocidal compositions and uses thereof
US4358443A (en) * 1980-04-14 1982-11-09 The Research Foundation Of State University Of New York Method and composition for controlling the growth of microorganisms
US4742083A (en) * 1983-08-24 1988-05-03 Lever Brothers Company Method of relieving pain and inflammatory conditions employing substituted salicylamides
US4939132A (en) * 1985-04-15 1990-07-03 The Research Foundation Of State University Of New York Novel 5-alkylsulfonylsalicylanilides and microbiocidal compositions for controlling the growth of microorganisms
US5958911A (en) * 1996-11-05 1999-09-28 The Research Foundation Of State University Of New York Method of relieving inflammation by using 5-alkylsulfonylsalicylanilides

Also Published As

Publication number Publication date
JP2004510756A (ja) 2004-04-08
CA2424396A1 (en) 2002-04-11
JP4086658B2 (ja) 2008-05-14
EP1328507A1 (en) 2003-07-23
CN1249019C (zh) 2006-04-05
US20020065322A1 (en) 2002-05-30
DE60127285D1 (de) 2007-04-26
EP1328507B1 (en) 2007-03-14
WO2002028819A1 (en) 2002-04-11
EP1328507A4 (en) 2005-07-27
CN1468210A (zh) 2004-01-14
ATE356798T1 (de) 2007-04-15
CA2424396C (en) 2009-12-08
MXPA03002891A (es) 2003-10-15
DE60127285T2 (de) 2007-12-20
DK1328507T3 (da) 2007-07-02
US6407288B1 (en) 2002-06-18

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