DK1303261T3 - Selv-emulgerende lægemiddelafgivelsessystemer til ekstremt vanduoplöselige, lipofile lægemidler - Google Patents

Selv-emulgerende lægemiddelafgivelsessystemer til ekstremt vanduoplöselige, lipofile lægemidler

Info

Publication number
DK1303261T3
DK1303261T3 DK01954879T DK01954879T DK1303261T3 DK 1303261 T3 DK1303261 T3 DK 1303261T3 DK 01954879 T DK01954879 T DK 01954879T DK 01954879 T DK01954879 T DK 01954879T DK 1303261 T3 DK1303261 T3 DK 1303261T3
Authority
DK
Denmark
Prior art keywords
self
drug delivery
delivery systems
lipophilic drugs
emulsifying drug
Prior art date
Application number
DK01954879T
Other languages
English (en)
Inventor
Walter Morozowich
Ping Gao
Narmada Shenoy
Original Assignee
Pharmacia & Upjohn Co Llc
Sugen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc, Sugen Inc filed Critical Pharmacia & Upjohn Co Llc
Application granted granted Critical
Publication of DK1303261T3 publication Critical patent/DK1303261T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Dispersion Chemistry (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK01954879T 2000-07-24 2001-07-20 Selv-emulgerende lægemiddelafgivelsessystemer til ekstremt vanduoplöselige, lipofile lægemidler DK1303261T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22037600P 2000-07-24 2000-07-24
PCT/US2001/023140 WO2002007712A2 (en) 2000-07-24 2001-07-20 Self-emulsifying drug delivery systems for extremely water-insoluble, lipophilic drugs

Publications (1)

Publication Number Publication Date
DK1303261T3 true DK1303261T3 (da) 2005-05-23

Family

ID=22823309

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01954879T DK1303261T3 (da) 2000-07-24 2001-07-20 Selv-emulgerende lægemiddelafgivelsessystemer til ekstremt vanduoplöselige, lipofile lægemidler

Country Status (14)

Country Link
US (1) US20020119198A1 (da)
EP (1) EP1303261B1 (da)
JP (1) JP2004504342A (da)
AR (1) AR030253A1 (da)
AT (1) ATE290372T1 (da)
AU (2) AU7709901A (da)
CA (1) CA2410683A1 (da)
DE (1) DE60109295T2 (da)
DK (1) DK1303261T3 (da)
ES (1) ES2238050T3 (da)
MX (1) MXPA03000720A (da)
PE (1) PE20020261A1 (da)
PT (1) PT1303261E (da)
WO (1) WO2002007712A2 (da)

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ITRM20030074A1 (it) * 2003-02-21 2004-08-22 Pharmacia Italia Spa Formulazioni semisolide a rilascio immediato intese
JP2007515458A (ja) * 2003-12-23 2007-06-14 テイボテク・フアーマシユーチカルズ・リミテツド Ｈｉｖプロテアーゼ阻害剤の自己ミクロ乳化性薬剤送達システム
AU2004308973A1 (en) * 2003-12-23 2005-07-14 Alza Corporation Methods and dosage forms for increasing solubility of drug compositions for controlled delivery
US7345093B2 (en) 2004-04-27 2008-03-18 Formatech, Inc. Methods of enhancing solubility of compounds
US7659310B2 (en) 2004-04-27 2010-02-09 Formatech, Inc. Methods of enhancing solubility of agents
EP1748759B1 (en) * 2004-04-27 2013-03-27 Javeri, Indu Methods of enhancing solubility in water of hydrophobic compounds by micellar dispersions
CN100361656C (zh) * 2004-08-27 2008-01-16 石药集团中奇制药技术（石家庄）有限公司 丁苯酞自乳化释药体系及其制备方法和应用
KR101391020B1 (ko) * 2005-03-14 2014-04-30 가부시키가이샤 오츠까 세이야꾸 고죠 수난용성 약제를 함유한 약학 조성물
US20160184258A1 (en) * 2005-11-07 2016-06-30 Murty Pharmaceuticals, Inc. Oral gastrointestinal dosage form delivery system of cannabinoids and/or standardized marijuana extracts
US20140357708A1 (en) * 2005-11-07 2014-12-04 Murty Pharmaceuticals, Inc. Oral dosage form of tetrahydrocannabinol and a method of avoiding and/or suppressing hepatic first pass metabolism via targeted chylomicron/lipoprotein delivery
MY153288A (en) * 2006-06-28 2015-01-29 Hovid Berhad An effective pharmaceutical carrier for poorly bioavailable drugs
CN101809024A (zh) * 2007-07-16 2010-08-18 铂雅制药公司 吡铂的口服制剂
EP2200613B1 (en) 2007-09-21 2018-09-05 The Johns Hopkins University Phenazine derivatives and uses thereof
EP2421496A4 (en) * 2009-04-22 2014-01-15 Agency Science Tech & Res EMULSIONS FOR TRANSDERMAL ADMINISTRATION
US10143652B2 (en) 2009-09-23 2018-12-04 Curirx Inc. Methods for the preparation of liposomes
EP2480209A1 (en) 2009-09-23 2012-08-01 Indu Javeri Methods for the preparation of liposomes comprising docetaxel
WO2011047259A1 (en) 2009-10-16 2011-04-21 Glaxosmithkline Llc Compositions
WO2012039768A2 (en) * 2010-09-24 2012-03-29 Texas Southern University Itraconazole formulations
US20120302954A1 (en) * 2011-05-25 2012-11-29 Zhao Jonathon Z Expandable devices coated with a paclitaxel composition
PT2782584T (pt) 2011-11-23 2021-09-02 Therapeuticsmd Inc Preparações e terapias de substituição para hormonoterapias naturais combinadas
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
CN102415995B (zh) * 2011-12-09 2013-11-13 广东众生药业股份有限公司 一种黄体酮过饱和自微乳组合物及其制备方法
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
MX2016011706A (es) * 2014-03-28 2017-05-01 Therapeuticsmd Inc Formulaciones de progesterona.
JP2017516768A (ja) 2014-05-22 2017-06-22 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． 天然の併用ホルモン補充療法剤及び療法
US10098894B2 (en) 2014-07-29 2018-10-16 Therapeuticsmd, Inc. Transdermal cream
US20160346219A1 (en) 2015-06-01 2016-12-01 Autotelic Llc Phospholipid-coated therapeutic agent nanoparticles and related methods
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
TW201718598A (zh) * 2015-08-27 2017-06-01 美國禮來大藥廠 Ｅｚｈ２抑制劑
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
JP6871542B2 (ja) * 2017-02-28 2021-05-12 国立大学法人横浜国立大学 無機物成形体およびその製造方法
WO2019051437A1 (en) * 2017-09-11 2019-03-14 Board Of Regents, The University Of Texas System COMPOSITIONS FOR ENHANCED MEDICATION DELIVERY
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

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US4816247A (en) * 1985-09-11 1989-03-28 American Cyanamid Company Emulsion compositions for administration of sparingly water soluble ionizable hydrophobic drugs
US6458373B1 (en) * 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
EP1014953B1 (en) * 1997-03-05 2012-04-25 Sugen, Inc. Formulations for hydrophobic pharmaceutical agents
CA2326485C (en) * 1998-04-01 2008-12-09 Rtp Pharma Inc. Anticancer compositions
US6221391B1 (en) * 1998-11-23 2001-04-24 Accucaps Industries Limited Self-emulsifying ibuprofen solution and soft gelatin capsule for use therewith
US20020102301A1 (en) * 2000-01-13 2002-08-01 Joseph Schwarz Pharmaceutical solid self-emulsifying composition for sustained delivery of biologically active compounds and the process for preparation thereof
DE10026698A1 (de) * 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung

Also Published As

Publication number Publication date
EP1303261B1 (en) 2005-03-09
ATE290372T1 (de) 2005-03-15
DE60109295T2 (de) 2006-04-13
MXPA03000720A (es) 2004-11-01
AU7709901A (en) 2002-02-05
ES2238050T3 (es) 2005-08-16
WO2002007712A2 (en) 2002-01-31
JP2004504342A (ja) 2004-02-12
PE20020261A1 (es) 2002-04-18
AU2001277099B2 (en) 2006-08-31
US20020119198A1 (en) 2002-08-29
AR030253A1 (es) 2003-08-13
DE60109295D1 (de) 2005-04-14
PT1303261E (pt) 2005-06-30
WO2002007712A3 (en) 2002-06-13
EP1303261A2 (en) 2003-04-23
CA2410683A1 (en) 2002-01-31

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