DK129844B - Analogifremgangsmåde til fremstilling af thieno[3,2-d]pyrimidiner. - Google Patents

Analogifremgangsmåde til fremstilling af thieno[3,2-d]pyrimidiner.

Info

Publication number
DK129844B
DK129844B DK219672AA DK219672A DK129844B DK 129844 B DK129844 B DK 129844B DK 219672A A DK219672A A DK 219672AA DK 219672 A DK219672 A DK 219672A DK 129844 B DK129844 B DK 129844B
Authority
DK
Denmark
Prior art keywords
thieno
pyrimidines
preparation
analogous process
analogous
Prior art date
Application number
DK219672AA
Other languages
Danish (da)
English (en)
Other versions
DK129844C (cs
Inventor
B Narr
J Roch
E Mueller
J Nickl
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19712121950 external-priority patent/DE2121950A1/de
Priority claimed from DE19712137341 external-priority patent/DE2137341A1/de
Priority claimed from DE19722215299 external-priority patent/DE2215299A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DK129844B publication Critical patent/DK129844B/da
Application granted granted Critical
Publication of DK129844C publication Critical patent/DK129844C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK219672AA 1971-05-04 1972-05-03 Analogifremgangsmåde til fremstilling af thieno[3,2-d]pyrimidiner. DK129844B (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19712121950 DE2121950A1 (en) 1971-05-04 1971-05-04 Thieno(3,2-d)pyrimidine derivs - with thrombocyte aggregation inhibiting activity
DE19712137341 DE2137341A1 (de) 1971-07-26 1971-07-26 Neue thieno eckige klammer auf 3,2-d eckige klammer zu pyrimidine
DE19722215299 DE2215299A1 (de) 1972-03-29 1972-03-29 Neue thieno eckige klammer auf 3,2-d eckige klammer zu pyrimidine

Publications (2)

Publication Number Publication Date
DK129844B true DK129844B (da) 1974-11-25
DK129844C DK129844C (cs) 1975-05-12

Family

ID=27183398

Family Applications (1)

Application Number Title Priority Date Filing Date
DK219672AA DK129844B (da) 1971-05-04 1972-05-03 Analogifremgangsmåde til fremstilling af thieno[3,2-d]pyrimidiner.

Country Status (15)

Country Link
US (1) US3888851A (cs)
AT (1) AT318619B (cs)
AU (1) AU4181572A (cs)
BE (1) BE783044A (cs)
BG (1) BG20593A3 (cs)
DD (1) DD97656A5 (cs)
DK (1) DK129844B (cs)
ES (1) ES402302A1 (cs)
FR (1) FR2135294B1 (cs)
GB (1) GB1393161A (cs)
HU (1) HU163960B (cs)
IL (1) IL39341A (cs)
NL (1) NL7206041A (cs)
PL (1) PL82381B1 (cs)
RO (1) RO62428A (cs)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054656A (en) * 1975-09-10 1977-10-18 Mead Johnson & Company Thieno[2,3-d]pyrimidine antiallergic agents
US5098902A (en) * 1991-03-18 1992-03-24 Warner-Lambert Company Method of treating neurodegenerative diseases
CA2129337A1 (en) * 1992-02-19 1993-09-02 Jotham W. Coe Heterocyclic compounds for enhancing antitumor activity
BR9812944A (pt) 1997-10-20 2000-08-08 Hoffmann La Roche Inibidores bicìclicos da cinase
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
GB0423653D0 (en) 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
PT1874781E (pt) * 2006-04-19 2009-07-27 Boehringer Ingelheim Int Di-hidro-tienopirimidinas para o tratamento de doenças inflamatórias
RU2439074C2 (ru) 2006-04-26 2012-01-10 Ф. Хоффманн-Ля Рош Аг ПРОИЗВОДНОЕ ТИЕНО[3,2-d]ПИРИМИДИНА В КАЧЕСТВЕ ИНГИБИТОРА ФОСФАТИДИЛИНОЗИТОЛ-3-КИНАЗЫ (РI3К)
DK2041139T3 (da) 2006-04-26 2012-01-16 Genentech Inc Farmaceutiske forbindelser
CN101511840A (zh) 2006-04-26 2009-08-19 吉宁特有限公司 磷酸肌醇3-激酶抑制剂化合物及其使用方法
CL2007003520A1 (es) 2006-12-07 2008-08-22 Piramed Ltd Genentech Inc Compuestos derivados de heterociclos sustituidos con morfolina, inhibidores de la actividad pi3 quinasa; composicion farmaceutica que comprende a dichos compuestos; kit farmaceutico; y su uso para el tratamiento profilactico o terapeutico del cancer.
RU2470936C2 (ru) * 2006-12-07 2012-12-27 Дженентек, Инк. Соединения-ингибиторы фосфоинозитид 3-киназы и способы применения
CN101932587A (zh) 2007-09-24 2010-12-29 吉宁特有限公司 噻唑并嘧啶pi3k抑制剂化合物及使用方法
AU2008313742B2 (en) * 2007-10-19 2013-11-28 Boehringer Ingelheim International Gmbh Heterocycle-substituted piperazino-dihydrothienopyrimidines
CN101909631B (zh) * 2007-10-25 2012-09-12 健泰科生物技术公司 制备噻吩并嘧啶化合物的方法
GB0721095D0 (en) 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
WO2010105008A2 (en) 2009-03-12 2010-09-16 Genentech, Inc. Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents for the treatment of hematopoietic malignancies
WO2010136491A1 (en) * 2009-05-27 2010-12-02 F. Hoffmann-La Roche Ag Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
AU2010254161A1 (en) * 2009-05-27 2011-11-10 F. Hoffmann-La Roche Ag Bicyclic pyrimidine PI3K inhibitor compounds selective for p110 delta, and methods of use
CN103038643A (zh) 2010-04-16 2013-04-10 基因泰克公司 作为pi3k/akt激酶途径抑制剂效能的预测性生物标记的foxo3a
WO2012088254A1 (en) 2010-12-22 2012-06-28 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
RU2015140573A (ru) 2013-02-25 2017-03-30 Дженентек, Инк. Способы и композиции для обнаружения и лечения устойчивого к лекарственным средствам мутанта акт
GB201410816D0 (en) * 2014-06-17 2014-07-30 Ucb Biopharma Sprl And Katholieke Universiteit Leuven Therapeutic agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3259623A (en) * 1963-06-14 1966-07-05 Olin Mathieson Process for preparing 2-(secondary amino)-halogenopyrimidines
DE1470356A1 (de) * 1964-01-15 1970-04-30 Thomae Gmbh Dr K Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
US3210368A (en) * 1964-09-29 1965-10-05 Ciba Geigy Corp Certain 2-amino-4-aryl-5-n, n-disubstituted amino-lower alkyl-thiazole compounds

Also Published As

Publication number Publication date
BG20593A3 (bg) 1975-12-05
FR2135294B1 (cs) 1975-10-17
GB1393161A (en) 1975-05-07
RO62428A (fr) 1978-01-15
ES402302A1 (es) 1975-04-01
AU4181572A (en) 1973-11-08
AT318619B (de) 1974-11-11
NL7206041A (cs) 1972-11-07
US3888851A (en) 1975-06-10
FR2135294A1 (cs) 1972-12-15
IL39341A (en) 1975-08-31
DD97656A5 (cs) 1973-05-12
HU163960B (cs) 1973-11-28
IL39341A0 (en) 1972-07-26
DK129844C (cs) 1975-05-12
PL82381B1 (cs) 1975-10-31
BE783044A (fr) 1972-11-06

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