DK1286962T3 - 2-Ethyl og 2-ethyliden-19-nor-vitamin D-forbindelser - Google Patents
2-Ethyl og 2-ethyliden-19-nor-vitamin D-forbindelserInfo
- Publication number
- DK1286962T3 DK1286962T3 DK01939792T DK01939792T DK1286962T3 DK 1286962 T3 DK1286962 T3 DK 1286962T3 DK 01939792 T DK01939792 T DK 01939792T DK 01939792 T DK01939792 T DK 01939792T DK 1286962 T3 DK1286962 T3 DK 1286962T3
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- ethylidene
- vitamin
- activity
- ethyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Reproductive Health (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Biomedical Technology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20819900P | 2000-05-31 | 2000-05-31 | |
PCT/US2001/017662 WO2001092221A1 (en) | 2000-05-31 | 2001-05-31 | 2-ethyl and 2-ethylidene-19-nor-vitamin d compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1286962T3 true DK1286962T3 (da) | 2008-10-06 |
Family
ID=22773624
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01939792T DK1286962T3 (da) | 2000-05-31 | 2001-05-31 | 2-Ethyl og 2-ethyliden-19-nor-vitamin D-forbindelser |
Country Status (15)
Country | Link |
---|---|
US (5) | US6806262B2 (de) |
EP (1) | EP1286962B1 (de) |
JP (1) | JP4022141B2 (de) |
AT (1) | ATE399151T1 (de) |
AU (2) | AU2001265272B2 (de) |
BR (1) | BR0111173A (de) |
CA (1) | CA2410880C (de) |
DE (1) | DE60134549D1 (de) |
DK (1) | DK1286962T3 (de) |
ES (1) | ES2309069T3 (de) |
IL (1) | IL152942A (de) |
MX (1) | MXPA02011820A (de) |
NZ (1) | NZ522909A (de) |
PT (1) | PT1286962E (de) |
WO (1) | WO2001092221A1 (de) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6392071B1 (en) * | 1997-03-17 | 2002-05-21 | Wisconsin Alumni: Research Foundation | 26,27-homologated-20-EPI-2-alkylidene-19-nor-vitamin D compounds |
DK1219599T3 (da) * | 1999-08-27 | 2010-05-25 | Hiroaki Takayama | Vitamin-D-derivater som har substituenter i 2-alfa-position |
US20030018017A1 (en) * | 2001-01-25 | 2003-01-23 | Deluca Hector F. | Method of treatment of type I diabetes |
WO2003084925A1 (en) * | 2002-03-29 | 2003-10-16 | Wisconsin Alumni Research Foundation | METHOD OF SYNTHESIZING 1α-HYDROXY-2-METHYLENE-19-NOR-HOMOPREGNACALCIFEROL |
US6846811B2 (en) * | 2002-04-22 | 2005-01-25 | Wisconsin Alumni Research Foundation | (20S) 1α-hydroxy-2α-methyl and 2β-methyl-19-nor-vitamin D3 and their uses |
WO2004033420A1 (ja) * | 2002-10-10 | 2004-04-22 | Chugai Pharmaceutical Co Ltd | 2,2−ジ置換−1α,25−ジヒドロキシ−19−ノルビタミンD誘導体 |
WO2004067504A1 (ja) * | 2003-01-31 | 2004-08-12 | Chugai Seiyaku Kabushiki Kaisha | 2位置換ビタミンd誘導体 |
EP1598360A4 (de) | 2003-02-25 | 2010-04-07 | Knc Lab Co Ltd | Neue zwischenprodukte für die synthese von vitamin-d-derivaten |
GB0305332D0 (en) * | 2003-03-10 | 2003-04-09 | Leuven K U Res & Dev | Biological evaluation of novel vitamin D analogues |
US20060293291A1 (en) * | 2003-04-10 | 2006-12-28 | Deluca Hector F | 2-Propylidene-19-nor-vitamin d compounds |
EP1641466B1 (de) * | 2003-07-03 | 2007-01-03 | Wisconsin Alumni Research Foundation | 2-methylen-19-nor-20(s)-25-methyl-1alpha-hydroxycalciferol und seine verwendungen |
ATE537834T1 (de) * | 2003-08-20 | 2012-01-15 | Wisconsin Alumni Res Found | 2-methylen-19-nor-vitamin d2-verbindungen |
NZ545632A (en) * | 2003-09-19 | 2009-09-25 | Wisconsin Alumni Res Found | 2-Alkylidene-19-nor-vitamin D derivatives for the treatment of frailty, muscle damage or sarcopenia |
WO2005027928A1 (en) * | 2003-09-19 | 2005-03-31 | Pfizer Products Inc. | 2-alkylidene-19-nor-vit amin d derivatives for the treatment of hypocalcemic tetany or hyproparathyroidism |
WO2005027917A1 (en) * | 2003-09-19 | 2005-03-31 | Pfizer Products Inc. | 2-alkylidene-19-nor-vitamin d derivatives for the treatment of osteopenia or male osteoporosis |
US7214670B2 (en) * | 2003-09-24 | 2007-05-08 | Wisconsin Alumni Research Foundation | Use of 2-methylene-19-nor-20(S)-1α,25-dihydroxyvitamin D3 to increase the life expectancy of human beings |
US7704980B2 (en) * | 2003-10-08 | 2010-04-27 | Wisconsin Alumni Research Foundation | Treatment of inflammatory bowel disease with 2-methylene-19-nor-vitamin D compounds |
US8404667B2 (en) * | 2006-12-29 | 2013-03-26 | Wisconsin Alumni Research Foundation | Compounds, compositions, kits and methods of use to orally and topically treat acne and other skin conditions by 19-Nor vitamin D analog |
US7713951B2 (en) * | 2004-04-09 | 2010-05-11 | Wisconsin Alumni Research Foundation | 2-alkylidene-18,19-dinor-vitamin D compounds |
WO2006051106A1 (en) | 2004-11-12 | 2006-05-18 | Bioxell Spa | Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer |
NZ555279A (en) * | 2004-11-22 | 2010-12-24 | Wisconsin Alumni Res Found | 2alpha-methyl-19-nor-1alpha-hydroxy-homopregnacalciferol and its uses |
NZ555282A (en) * | 2004-11-22 | 2010-12-24 | Wisconsin Alumni Res Found | 17,20(z)-dehydro vitamin D analogs and their uses |
MX2007006543A (es) * | 2004-11-22 | 2007-07-25 | Wisconsin Alumni Res Found | 2-metilen-19,26,27-trinor-(20s)-1a-hidroxivitamina d3 y sus usos. |
US7241751B2 (en) * | 2004-11-22 | 2007-07-10 | Wisconsin Alumi Research Foundation | 2α-methyl-19-nor-(20S)-1α-hydroxy-bishomopregnacalciferol and its uses |
JP2008520689A (ja) | 2004-11-22 | 2008-06-19 | ウィスコンシン・アルムニ・リサーチ・ファウンデーション | 19,26,27−トリノル−(20S)−1α−ヒドロキシビタミンD3の2α−メチルおよび2β−メチル類似体およびそれらの使用 |
WO2006119309A2 (en) * | 2005-05-03 | 2006-11-09 | Wisconsin Alumni Research Foundation | 19,26,27-TRINOR-1α,25-DIHYDROXYVITAMIN D3 COMPOUNDS |
US7528122B2 (en) * | 2006-02-02 | 2009-05-05 | Wisconsin Alumni Research Foundation | Vitamin D analog—NEL, methods and uses thereof |
US7803789B2 (en) * | 2006-02-02 | 2010-09-28 | Wisconsin Alumni Research Foundation | Vitamin D analog—RAK, methods and uses thereof |
US20090281340A1 (en) * | 2006-04-05 | 2009-11-12 | Deluca Hector F | 1alpha-hydroxy-2-(3'-hydroxypropylidene)-19-nor-vitamin d compounds and methods of making and treatment thereof |
NZ571896A (en) | 2006-04-05 | 2011-09-30 | Wisconsin Alumni Res Found | 1-Alpha.-hydroxy-2-(3'-hydroxypropylidene)-19-nor-vitamin D compounds and methods of making and use thereof |
JP2010505739A (ja) * | 2006-04-06 | 2010-02-25 | ウイスコンシン アラムニ リサーチ ファンデーション | 2−メチレン−1α,25−ジヒドロキシ−19,21−ジノルビタミンD3類縁体およびその使用 |
AU2007349772A1 (en) * | 2006-04-06 | 2008-10-23 | Wisconsin Alumni Research Foundation | 2-methylene-1alpha,25-dihydroxy-18,19,21-trinorvitamin D3 and uses thereof |
EP2021320A2 (de) * | 2006-04-06 | 2009-02-11 | Wisconsin Alumni Research Foundation | 2-substituierte 1-alpha-25-dihydroxy-19,26,27-trinor-vitamin-d-analoge und deren anwendungen |
MX2009003241A (es) * | 2006-09-28 | 2009-05-05 | Wisconsin Alumni Res Found | Analogos de 2-metilen-(20r,25s)-19,27-dinor-(22e)-vitamina d. |
WO2008039751A2 (en) * | 2006-09-28 | 2008-04-03 | Wisconsin Alumni Research Foundation | 2-methylene-(20s,25s)-19,27-dinor-(22e)-vitamin d analogs |
US7888339B2 (en) * | 2008-07-10 | 2011-02-15 | Wisconsin Alumni Research Foundation | 2-methylene-20(21)-dehydro-19-nor-vitamin D analogs |
US8222236B2 (en) * | 2008-07-10 | 2012-07-17 | Wisconsin Alumni Research Foundation | 2-methylene-(20E)-20(22)-dehydro-19-nor-vitamin D analogs |
US7893043B2 (en) * | 2008-07-10 | 2011-02-22 | Wisconsin Alumni Research Foundation | 2-methylene-(17Z)-17(20)-dehydro-19,21-dinor-vitamin D analogs |
WO2011119622A1 (en) * | 2010-03-23 | 2011-09-29 | Wisconsin Alumni Research Foundation | DIASTEREOMERS OF 2-METHYLENE-19-NOR-22-METHYL-1α,25- DIHYDROXYVITAMIN D3 |
US8664206B2 (en) | 2010-03-23 | 2014-03-04 | Wisconsin Alumni Research Foundation | Diastereomers of 2-methylene-19-nor-22-methyl-1α,25-dihydroxyvitamin D3 |
WO2011119610A2 (en) * | 2010-03-23 | 2011-09-29 | Wisconsin Alumni Research Foundation | (20S)-2-METHYLENE-19-NOR-22-DIMETHYL-1α,25- DIHYDROXYVITAMIN D3 AND (20R)-2-METHYLENE-19-NOR-22- DIMETHYL-1α,25-HYDROXYVITAMIN D3 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4666634A (en) | 1984-12-05 | 1987-05-19 | Chugai Seiyaku Kabushiki Kaisha | vitamin D3 derivatives having a substituent at 2-position |
CA1333616C (en) | 1989-03-09 | 1994-12-20 | Hector F. Deluca | 19-nor-vitamin d compounds |
NZ232734A (en) | 1989-03-09 | 1991-11-26 | Wisconsin Alumni Res Found | 19-nor vitamin d derivatives and pharmaceutical compositions |
US5246925A (en) | 1989-03-09 | 1993-09-21 | Wisconsin Alumni Research Foundation | 19-nor-vitamin D compounds for use in treating hyperparathyroidism |
DK0474517T3 (da) | 1990-09-07 | 1999-08-02 | Wisconsin Alumni Res Found | Hidtil ukendt anvendelse af 1alfa-hydroxyleret-19-nor-vitamin D- |
US5086191A (en) | 1991-05-28 | 1992-02-04 | Wisconsin Alumni Research Foundation | Intermediates for the synthesis of 19-nor vitamin D compounds |
AU650751B2 (en) | 1991-05-28 | 1994-06-30 | Wisconsin Alumni Research Foundation | Novel synthesis of 19-nor vitamin D compounds |
ZA924811B (en) | 1991-06-28 | 1993-12-29 | Endorecherche Inc | Controlled release systems and low dose androgens |
DE69400495T2 (de) | 1993-04-05 | 1997-04-30 | Wisconsin Alumni Res Found | 19-Nor-vitamin-D3-Verbindung mit einem Substituent an die 2. Stelle |
US5565589A (en) | 1993-11-03 | 1996-10-15 | Wisconsin Alumni Research Foundation | 17-formyl-5,6-trans-vitamin D compounds |
US5428029A (en) | 1993-11-24 | 1995-06-27 | Hoffmann-La Roche Inc. | Vitamin D3 fluorinated analogs |
WO1996001811A1 (en) | 1994-07-11 | 1996-01-25 | The Johns-Hopkins University | 2-substituted 1,25-dihydroxyvitamin d3 derivatives |
EP0793649B1 (de) | 1994-11-21 | 1999-02-03 | Wisconsin Alumni Research Foundation | 18,19-dinor-vitamin-d-derivate |
US5877168A (en) * | 1995-02-10 | 1999-03-02 | Chugai Seiyaku Kabushiki Kaisha | Vitamin D derivative with substituent at the 2β-position |
IL118156A (en) | 1995-05-09 | 2001-08-26 | Duphar Int Res | Vitamin d compounds, their preparation and pharmaceutical compositions containing them |
ATE289199T1 (de) | 1995-06-06 | 2005-03-15 | Merck & Co Inc | Formulierungen mit dem wasserfreien mononatriumsalz von alendronat und deren verwendung zur behandlung von knochenkrankheiten |
US5843928A (en) | 1997-03-17 | 1998-12-01 | Wisconsin Alumni Research Foundation | 2-alkylidene-19-nor-vitamin D compounds |
US5945410A (en) * | 1997-03-17 | 1999-08-31 | Wisconsin Alumni Research Foundation | 2-alkyl-19-nor-vitamin D compounds |
-
2001
- 2001-05-31 US US09/871,227 patent/US6806262B2/en not_active Expired - Lifetime
- 2001-05-31 EP EP01939792A patent/EP1286962B1/de not_active Expired - Lifetime
- 2001-05-31 IL IL152942A patent/IL152942A/en not_active IP Right Cessation
- 2001-05-31 WO PCT/US2001/017662 patent/WO2001092221A1/en active IP Right Grant
- 2001-05-31 AU AU2001265272A patent/AU2001265272B2/en not_active Ceased
- 2001-05-31 DK DK01939792T patent/DK1286962T3/da active
- 2001-05-31 CA CA002410880A patent/CA2410880C/en not_active Expired - Fee Related
- 2001-05-31 ES ES01939792T patent/ES2309069T3/es not_active Expired - Lifetime
- 2001-05-31 PT PT01939792T patent/PT1286962E/pt unknown
- 2001-05-31 MX MXPA02011820A patent/MXPA02011820A/es active IP Right Grant
- 2001-05-31 JP JP2002500836A patent/JP4022141B2/ja not_active Expired - Lifetime
- 2001-05-31 DE DE60134549T patent/DE60134549D1/de not_active Expired - Lifetime
- 2001-05-31 AU AU6527201A patent/AU6527201A/xx active Pending
- 2001-05-31 NZ NZ522909A patent/NZ522909A/en not_active IP Right Cessation
- 2001-05-31 AT AT01939792T patent/ATE399151T1/de active
- 2001-05-31 BR BR0111173-6A patent/BR0111173A/pt not_active Application Discontinuation
-
2004
- 2004-10-01 US US10/957,483 patent/US6992074B2/en not_active Expired - Lifetime
-
2005
- 2005-07-28 US US11/191,791 patent/US7141558B2/en not_active Expired - Lifetime
-
2006
- 2006-11-22 US US11/603,721 patent/US7300925B2/en not_active Expired - Lifetime
-
2007
- 2007-08-16 US US11/839,586 patent/US7468361B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
IL152942A0 (en) | 2003-06-24 |
BR0111173A (pt) | 2003-04-29 |
IL152942A (en) | 2007-09-20 |
US20070088008A1 (en) | 2007-04-19 |
AU2001265272B2 (en) | 2006-08-17 |
US7468361B2 (en) | 2008-12-23 |
CA2410880A1 (en) | 2001-12-06 |
US20080032956A1 (en) | 2008-02-07 |
US6806262B2 (en) | 2004-10-19 |
US6992074B2 (en) | 2006-01-31 |
MXPA02011820A (es) | 2003-04-10 |
CA2410880C (en) | 2009-03-03 |
EP1286962B1 (de) | 2008-06-25 |
JP4022141B2 (ja) | 2007-12-12 |
ATE399151T1 (de) | 2008-07-15 |
WO2001092221A1 (en) | 2001-12-06 |
JP2004501114A (ja) | 2004-01-15 |
US20030013691A1 (en) | 2003-01-16 |
EP1286962A1 (de) | 2003-03-05 |
US7300925B2 (en) | 2007-11-27 |
NZ522909A (en) | 2004-09-24 |
US7141558B2 (en) | 2006-11-28 |
AU6527201A (en) | 2001-12-11 |
ES2309069T3 (es) | 2008-12-16 |
US20050282789A1 (en) | 2005-12-22 |
US20050043281A1 (en) | 2005-02-24 |
DE60134549D1 (de) | 2008-08-07 |
PT1286962E (pt) | 2008-07-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1286962T3 (da) | 2-Ethyl og 2-ethyliden-19-nor-vitamin D-forbindelser | |
AR008853A1 (es) | Nuevos compuestos farmaceuticamente activos, su uso en la fabricacion de medicamentos, metodo de tratamiento, composicion farmaceutica, compuestosintermediarios y proceso para la fabricacion de dichos compuestos | |
ES2191192T3 (es) | Tienopirimidinas. | |
NZ514574A (en) | Novel method of treatment | |
CR7420A (es) | Composiciones farmaceuticas que comprenden uno o varios esteroides, uno o varios componentes de tetrahiidrofolatos y vitamina b12 | |
BR0012450A (pt) | Benzimidazóis substituìdos | |
AR039985A1 (es) | Compuesto de pirimidinona, composicion farmaceutica que lo comprende y su uso para la elaboracion de esta ultima | |
FI953515A0 (fi) | Fluoksetiinin farmaseuttiset formulaatiot | |
ATE219363T1 (de) | Lösliche prodrugs von paclitaxel | |
EA200400881A1 (ru) | Азаарилпиперазины | |
FI972744A0 (fi) | Aminohappokokoonpanoja ja niiden käyttö kliinisessä ravinnossa | |
ES2136673T3 (es) | Utilizacion del factor de crecimiento de los queratinocitos para la obtencion de medicamentos. | |
JPS55136229A (en) | Adjustment of bone metabolism in warm-blooded animal and drug for it | |
DE60015508D1 (de) | C-16 ungesätigte fp-selektive prostaglandin analoge | |
Fujita et al. | An experimental study on viability of the devascularized trachea | |
PT762883E (pt) | Piridilbisfosfonatos utilizaveis como agentes terapeuticos | |
EP1524264A3 (de) | 2-Ethyliden-19-Nor-Vitamin D-Verbindungen | |
MX9307079A (es) | Mejoras en composiciones farmaceuticas para el tratamiento de trastornos funcionales de las vias intestinales y mejoras en un procedimiento para la preparacion de dichas composiciones. | |
ATE198049T1 (de) | Behandlung von magen- und darmgeschwüren mit morphogenen | |
AU2001284657B2 (en) | Use of vitamin d derivatives as bone resorption inhibitors | |
WO2005056520A8 (en) | Somatostatin receptor subtype 1 (sstr1) active compounds and their use in therapy | |
DE60006379D1 (de) | Vitamin d-analogen und ihre pharmazeutische verwendung | |
MX9305152A (es) | Metodo para el tratamiento de enfermedades obstructivas y reversibles de las vias respiratorias. | |
RU2001131557A (ru) | Аналоги витамина D и их фармацевтическое использование | |
LV11524A (lv) | Benzidamina izmantosana TNF izsaukto patologisko stavoklu arstesana |