DK1283985T3 - Fremgangsmåde og apparat for patch-clamp målinger på celler - Google Patents

Fremgangsmåde og apparat for patch-clamp målinger på celler

Info

Publication number
DK1283985T3
DK1283985T3 DK01960595T DK01960595T DK1283985T3 DK 1283985 T3 DK1283985 T3 DK 1283985T3 DK 01960595 T DK01960595 T DK 01960595T DK 01960595 T DK01960595 T DK 01960595T DK 1283985 T3 DK1283985 T3 DK 1283985T3
Authority
DK
Denmark
Prior art keywords
capillary
cell
patch
cells
clamp measurements
Prior art date
Application number
DK01960595T
Other languages
Danish (da)
English (en)
Inventor
Albrecht Lepple-Wienhues
Original Assignee
Flyion Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flyion Gmbh filed Critical Flyion Gmbh
Application granted granted Critical
Publication of DK1283985T3 publication Critical patent/DK1283985T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48728—Investigating individual cells, e.g. by patch clamp, voltage clamp

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
DK01960595T 2000-07-31 2001-07-31 Fremgangsmåde og apparat for patch-clamp målinger på celler DK1283985T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00116515A EP1178315A1 (fr) 2000-07-31 2000-07-31 Dispositif et procédé pour examiner des cellules à l'aide de la méthode patch-clamp

Publications (1)

Publication Number Publication Date
DK1283985T3 true DK1283985T3 (da) 2006-10-09

Family

ID=8169404

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01960595T DK1283985T3 (da) 2000-07-31 2001-07-31 Fremgangsmåde og apparat for patch-clamp målinger på celler

Country Status (12)

Country Link
US (1) US7611861B2 (fr)
EP (2) EP1178315A1 (fr)
JP (1) JP2004518109A (fr)
CN (1) CN1327222C (fr)
AT (1) ATE329261T1 (fr)
AU (1) AU8204801A (fr)
CA (1) CA2417796A1 (fr)
DE (1) DE60120396T2 (fr)
DK (1) DK1283985T3 (fr)
ES (1) ES2266235T3 (fr)
HK (1) HK1061889A1 (fr)
WO (1) WO2002010747A2 (fr)

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AU2002365542A1 (en) * 2001-11-27 2003-06-10 Cellectricon Ab A method for combined parallel agent delivery and electroporation for cell structures and use thereof
WO2003068906A1 (fr) * 2002-02-12 2003-08-21 Cellectricon Ab Systemes et procedes de changement rapide de l'environnement liquide autour de capteurs
ES2208082B1 (es) * 2002-05-29 2005-09-16 Jose Luis Bardasano Rubio Dispositivo para la medida del potencial de la accion transmembrana en preparaciones celulares bajo la accion de campos electromagneticos de frecuencia e intensidad variables.
EP1546348A4 (fr) * 2002-08-21 2005-12-14 Cellectricon Ab Systeme et procede destines a obtenir et a maintenir des joints haute resistance dans des enregistrements de patch-clamp
US8232074B2 (en) 2002-10-16 2012-07-31 Cellectricon Ab Nanoelectrodes and nanotips for recording transmembrane currents in a plurality of cells
FR2866958B1 (fr) 2004-02-26 2006-08-04 Commissariat Energie Atomique Procede et dispositif de controle du positionnement d'un element biologique sur un support
US8058056B2 (en) * 2004-03-12 2011-11-15 The Regents Of The University Of California Method and apparatus for integrated cell handling and measurements
US20060134772A1 (en) * 2004-11-18 2006-06-22 The Regents Of The University Of California System for locating cells and for cellular analysis
WO2007108773A1 (fr) * 2006-03-23 2007-09-27 Agengy For Science, Technology And Research Dispositif d'analyse de l'état d'une particule
DE102006014513A1 (de) * 2006-03-23 2007-09-27 Flyion Gmbh Glaspipette oder Glaskapillare für Patch-Clamp-Experimente
US8293524B2 (en) * 2006-03-31 2012-10-23 Fluxion Biosciences Inc. Methods and apparatus for the manipulation of particle suspensions and testing thereof
US8361094B2 (en) 2006-06-30 2013-01-29 Atheromed, Inc. Atherectomy devices and methods
EP2037821B1 (fr) 2006-06-30 2022-06-22 Atheromed, Inc. Dispositifs d'athérectomie
US8920448B2 (en) 2006-06-30 2014-12-30 Atheromed, Inc. Atherectomy devices and methods
US20090018566A1 (en) 2006-06-30 2009-01-15 Artheromed, Inc. Atherectomy devices, systems, and methods
US8070762B2 (en) 2007-10-22 2011-12-06 Atheromed Inc. Atherectomy devices and methods
EP2302375B1 (fr) * 2009-09-29 2012-09-12 Karlsruher Institut für Technologie Procédé et dispositif de saisie de la courbe de tension de courant d'une cellule
CN102380357B (zh) * 2010-08-31 2014-07-02 北京大学 贴壁培养细胞层作为固定相的毛细管及其制备方法和用途
DE102014203280B4 (de) 2014-02-24 2015-12-17 Cytocentrics Bioscience Gmbh Vorrichtung zur Bestimmung von Messgrößen an Membranen
CN106033069B (zh) * 2015-03-10 2019-05-28 中国科学院生物物理研究所 单个囊泡融合和回收及其与钙离子通道耦合的膜片钳检测装置
US10167502B2 (en) 2015-04-03 2019-01-01 Fluxion Biosciences, Inc. Molecular characterization of single cells and cell populations for non-invasive diagnostics
US10830758B2 (en) * 2015-08-09 2020-11-10 Georgia Tech Research Corporation Systems and methods enabling patch-clamp re-use
CN108489867B (zh) * 2018-04-19 2020-01-31 中国科学院地球化学研究所 一种测定植物叶片细胞输运能力的方法
CN109374875A (zh) * 2018-11-20 2019-02-22 中国科学院生物物理研究所 低噪恒温重力灌流膜片钳装置
EP3884273A1 (fr) * 2018-11-20 2021-09-29 F. Hoffmann-La Roche AG Procédé d'ensemencement de cellules sur une surface de capteur
CN112345616B (zh) * 2020-09-14 2022-03-11 中国科学院生物物理研究所 一种适于单细胞及亚细胞水平生物活性物质检测的高精度电化学检测方法
CN112280667A (zh) * 2020-10-20 2021-01-29 深圳麦科田生物医疗技术有限公司 一种单个细胞提取方法
US11304723B1 (en) 2020-12-17 2022-04-19 Avantec Vascular Corporation Atherectomy devices that are self-driving with controlled deflection
CN113281441A (zh) * 2021-05-19 2021-08-20 中国科学技术大学 单细胞器质谱检测方法、检测装置
CN113406316B (zh) * 2021-06-17 2023-08-08 重庆医科大学附属儿童医院 一种电生理膜片钳灌流装置
EP4231011A1 (fr) * 2022-02-16 2023-08-23 Luigs & Neumann Feinmechanik und Elektrotechnik GmbH Dispositifs et procédés pour les techniques de mesure de type patch clamp

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EP0938674B1 (fr) * 1996-11-16 2005-06-01 NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen in Reutlingen Stiftung Bürgerlichen Rechts Systeme de microelements, procede de mise en contact de cellules situees dans un environnement liquide et procede permettant de realiser un systeme de microelements
DE19712309A1 (de) * 1996-11-16 1998-05-20 Nmi Univ Tuebingen Mikroelementenanordnung, Verfahren zum Kontaktieren von in einer flüssigen Umgebung befindlichen Zellen und Verfahren zum Herstellen einer Mikroelementenanordnung
DE19744649C2 (de) * 1997-10-09 2003-03-27 Fraunhofer Ges Forschung Verfahren zur Messung bioelektrischer Signale von Zellen nach der Patch-Clamp-Methode sowie Verwendung einer Vorrichtung hierzu
ATE205300T1 (de) * 1997-12-17 2001-09-15 Ecole Polytech Positionierung und elektrophysiologische charakterisierung einzelner zellen und rekonstituierter membransysteme auf mikrostrukturierten trägern
WO1999045985A1 (fr) * 1998-03-13 1999-09-16 Becton Dickinson And Company Procede d'assemblage et de conditionnement de dispositifs medicaux
JPH11299496A (ja) * 1998-04-24 1999-11-02 Hitachi Ltd 卵母細胞用容器およびそれを用いた計測装置
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DE19948473A1 (de) * 1999-10-08 2001-04-12 Nmi Univ Tuebingen Verfahren und Vorrichtung zum Messen an in einer flüssigen Umgebung befindlichen Zellen
GB9930719D0 (en) * 1999-12-24 2000-02-16 Central Research Lab Ltd Apparatus for and method of making electrical measurements on an object in a m edium

Also Published As

Publication number Publication date
EP1283985B1 (fr) 2006-06-07
CN1466681A (zh) 2004-01-07
EP1178315A1 (fr) 2002-02-06
CN1327222C (zh) 2007-07-18
ATE329261T1 (de) 2006-06-15
AU8204801A (en) 2002-02-13
HK1061889A1 (en) 2004-10-08
EP1283985A2 (fr) 2003-02-19
CA2417796A1 (fr) 2002-02-07
DE60120396T2 (de) 2007-06-06
DE60120396D1 (de) 2006-07-20
JP2004518109A (ja) 2004-06-17
US20030022268A1 (en) 2003-01-30
US7611861B2 (en) 2009-11-03
ES2266235T3 (es) 2007-03-01
WO2002010747A2 (fr) 2002-02-07
WO2002010747A3 (fr) 2002-04-18

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