DK1276878T3 - Reversibel immortalisering - Google Patents

Reversibel immortalisering

Info

Publication number
DK1276878T3
DK1276878T3 DK01915354.3T DK01915354T DK1276878T3 DK 1276878 T3 DK1276878 T3 DK 1276878T3 DK 01915354 T DK01915354 T DK 01915354T DK 1276878 T3 DK1276878 T3 DK 1276878T3
Authority
DK
Denmark
Prior art keywords
gene
cells
complex
region
immortalizing
Prior art date
Application number
DK01915354.3T
Other languages
English (en)
Inventor
Reinhard Kandolf
Anne Kuhn
Jan-Heiner Kuepper
Original Assignee
Medicyte Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicyte Gmbh filed Critical Medicyte Gmbh
Application granted granted Critical
Publication of DK1276878T3 publication Critical patent/DK1276878T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Prostheses (AREA)
DK01915354.3T 2000-04-17 2001-03-15 Reversibel immortalisering DK1276878T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10019195A DE10019195B4 (de) 2000-04-17 2000-04-17 Reversible Immortalisierung
PCT/EP2001/002967 WO2001078757A2 (de) 2000-04-17 2001-03-15 Reversible immortalisierung

Publications (1)

Publication Number Publication Date
DK1276878T3 true DK1276878T3 (da) 2011-03-28

Family

ID=7639184

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01915354.3T DK1276878T3 (da) 2000-04-17 2001-03-15 Reversibel immortalisering

Country Status (9)

Country Link
US (3) US20030161819A1 (da)
EP (1) EP1276878B1 (da)
JP (1) JP5313425B2 (da)
AT (1) ATE491033T1 (da)
AU (1) AU4247201A (da)
CA (1) CA2406171C (da)
DE (2) DE10019195B4 (da)
DK (1) DK1276878T3 (da)
WO (1) WO2001078757A2 (da)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2112673A1 (en) * 1991-07-01 1993-01-21 Raju Kucherlapati Interstitial deletion in chromosomal dna
DE4444949C1 (de) * 1994-12-16 1996-11-21 Deutsches Krebsforsch Vektoren und Viren zur Gentherapie
DE19757984A1 (de) * 1997-12-24 1999-07-01 Bayer Ag Regulatorische DNA-Sequenzen aus der 5'-Region vom Gen der humanen katalytischen Telomerase-Untereinheit udn deren diagnostische und therapeutische Verwendung
WO1999035245A2 (en) * 1998-01-12 1999-07-15 Board Of Regents, The University Of Texas System Methods for preparing and using immortalized human neuroendocrine cells
WO1999036562A1 (en) * 1998-01-14 1999-07-22 Human Gene Therapy Research Institute Nucleotide expression systems with reduced immunogenicity for use in gene therapy
CA2338487A1 (en) * 1998-07-28 2000-02-10 Advanced Tissue Sciences, Inc. Genetically engineered cells and tissues
AU6162199A (en) * 1998-09-25 2000-04-17 Harvard-Mit Division Of Health Science And Technology Reversibly immortalized hepatocytes and methods of use
US6630324B1 (en) * 1999-07-29 2003-10-07 Baylor College Of Medicine Aldehyde reductase bidirectional promoter and its use
US6399384B1 (en) * 1999-09-17 2002-06-04 Reneuron Limited Conditional immortalization of cells

Also Published As

Publication number Publication date
WO2001078757A2 (de) 2001-10-25
WO2001078757A3 (de) 2002-03-07
CA2406171A1 (en) 2002-10-11
AU4247201A (en) 2001-10-30
DE50115733D1 (de) 2011-01-20
CA2406171C (en) 2014-06-03
JP2003533984A (ja) 2003-11-18
US20030161819A1 (en) 2003-08-28
EP1276878A2 (de) 2003-01-22
ATE491033T1 (de) 2010-12-15
DE10019195A1 (de) 2001-10-25
DE10019195B4 (de) 2006-03-09
EP1276878B1 (de) 2010-12-08
US20100047218A1 (en) 2010-02-25
US20140087470A1 (en) 2014-03-27
JP5313425B2 (ja) 2013-10-09

Similar Documents

Publication Publication Date Title
ATE464372T1 (de) Expansion erneuerbarer stammzellpopulationen
DK1220893T3 (da) Medium til protein-fri og serum-fri dyrkning af celler
NO20061470L (no) Fremgangsmate for fremstilling av gamma-karboksylerte proteiner
AU2003208567A1 (en) Methods of inducing differentiation in stem cells, methods of generating tissue using scaffold matrices derived from micro-organs and stem cells, methods of producing adult stem cells and methods of continuously generating stem cells by implantation of micro-organs as sources of stem cells
SE9900519D0 (sv) A method for the preparation of UHMWPE doped with an antioxidant and an implant made thereof
EA200001129A2 (ru) Способ получения 4-карбоксиамино-2-замещенного-1,2,3,4-тетрагидрохинолина
NO20044882L (no) Acyl-4-karboksylfenylurinstoffderivater, deres fremstilling og anvendelse
GB0616672D0 (en) Timing synchronization and beacon generation for mesh points operating in a wirless mesh network
DK1208205T3 (da) Fremgangsmåder til frembringelse af L-aminosyrer ved hjælp af en forögelse af cellulært NADPH
MXPA05011522A (es) Derivados de 2-acilamino-4-feniltiazol, metodo para su preparacion y su aplicacion en terapeutica.
CY1106821T1 (el) Μεθοδος για την καλλιεργεια υποκαταστατου χονδρου και βιολογικη μητρα, παραγομενη συμφωνα με τη μεθοδο αυτη
RS20060250A (en) 1-amino-2-oxy-substituted tetrahydronaphtalene derivatives, method for the production thereof, and their use as antiphlogistics
BRPI0514074A (pt) aperfeiçoamentos em composições em bloco para lavatório
RU2013102427A (ru) Способ приготовления стабилизатора, ускорителя вулканизации или модифицированного посредством микроорганизма природного каучука
ATE518960T1 (de) Gentechnisch hergestellte zinkfingerproteine zur regulation der genexpression
MX2007002833A (es) Derivados de alquiliden-tetrahidronaftaleno, procedimiento para su preparacion y su uso como antiinflamatorios.
CY1111775T1 (el) Πνευμονικα κυτταρα βαμβακοαρουραιου για καλλιεργεια ιου
SV2006002188A (es) Derivados de cci - 779 y metodos para su preparacion ref. am-101759salvo
NO20050247L (no) Lavmolekylaert oversulfatert polysakkarid
AR030735A1 (es) Un procedimiento para la produccion de un extracto de champinon natural
DE50115733D1 (de) Reversible immortalisierung
ATE403005T1 (de) Rekombinantes mva und verfahren zur erzeugung davon
MXPA05006106A (es) 17.beta-(alpha-hidroxi)-esteres de androstanos como intermediarios para la preparacion de esteres androstanos 17.beta.-fluorinados.
BR112021020501A2 (pt) Meio de cultura celular para células eucarióticas
EA200400876A1 (ru) Способ получения производных толуола