DK1274429T3 - Topiske formuleringer til transdermal indgivelse af niacin-prolægemidler samt metoder til behandling af hyperlipidæmi - Google Patents

Topiske formuleringer til transdermal indgivelse af niacin-prolægemidler samt metoder til behandling af hyperlipidæmi

Info

Publication number
DK1274429T3
DK1274429T3 DK01930535T DK01930535T DK1274429T3 DK 1274429 T3 DK1274429 T3 DK 1274429T3 DK 01930535 T DK01930535 T DK 01930535T DK 01930535 T DK01930535 T DK 01930535T DK 1274429 T3 DK1274429 T3 DK 1274429T3
Authority
DK
Denmark
Prior art keywords
hyperlipidemia
treatment
methods
transdermal administration
topical formulations
Prior art date
Application number
DK01930535T
Other languages
Danish (da)
English (en)
Inventor
Myron K Jacobson
Hyuntae Kim
Moonsun Kim
Elaine L Jacobson
Jaber G Qasem
Original Assignee
Niadyne Corp
Univ Kentucky Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22730106&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1274429(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Niadyne Corp, Univ Kentucky Res Found filed Critical Niadyne Corp
Application granted granted Critical
Publication of DK1274429T3 publication Critical patent/DK1274429T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK01930535T 2000-04-14 2001-04-16 Topiske formuleringer til transdermal indgivelse af niacin-prolægemidler samt metoder til behandling af hyperlipidæmi DK1274429T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19762100P 2000-04-14 2000-04-14
PCT/US2001/012356 WO2001078727A1 (en) 2000-04-14 2001-04-16 Topical formulations for the transdermal delivery of niacin and methods of treating hyperlipidemia

Publications (1)

Publication Number Publication Date
DK1274429T3 true DK1274429T3 (da) 2008-08-25

Family

ID=22730106

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01930535T DK1274429T3 (da) 2000-04-14 2001-04-16 Topiske formuleringer til transdermal indgivelse af niacin-prolægemidler samt metoder til behandling af hyperlipidæmi

Country Status (14)

Country Link
US (1) US6677361B2 (de)
EP (1) EP1274429B1 (de)
JP (1) JP4156841B2 (de)
CN (1) CN1430513B (de)
AT (1) ATE395061T1 (de)
AU (2) AU2001257063B2 (de)
CA (1) CA2441461C (de)
DE (1) DE60134002D1 (de)
DK (1) DK1274429T3 (de)
ES (1) ES2302732T3 (de)
HK (1) HK1053607A1 (de)
MX (1) MXPA02010184A (de)
PT (1) PT1274429E (de)
WO (1) WO2001078727A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6464992B2 (en) * 2000-04-14 2002-10-15 University Of Kentucky Research Foundation Topical micronutrient delivery system and uses thereof
US20040081672A1 (en) * 2002-10-25 2004-04-29 Gupta Shyam K. Niacinamide, niacin, and niacin esters based delivery systems for treating topical disorders of skin and skin aging
US20040191278A1 (en) * 2003-03-31 2004-09-30 Christensen Flemming Kjaergaar Topical agent for application to the skin prior to luminous treatment
US20040254202A1 (en) * 2003-06-13 2004-12-16 The Procter & Gamble Company Method of promoting sleep using topical administration of vasoactive agents
US20050267091A1 (en) * 2004-05-25 2005-12-01 Roger Berlin Compositions containing policosanol and niacin and/or niacin derivatives and their pharmaceutical uses
JP5699414B2 (ja) * 2007-02-28 2015-04-08 ユニバーシティー オブ ケンタッキー リサーチ ファウンデイション レチノイン酸療法の効力を妨げることなくレチノイン酸療法の副作用を軽減する方法、および／又は、その効力を改善する方法
WO2008126088A2 (en) * 2007-04-15 2008-10-23 Oron Zachar Anti-pyretic vasodilators
CN102532114B (zh) * 2011-12-19 2016-08-03 中山大学 烟酸衍生物,其制备方法及其药物组合物
CA2947308A1 (en) 2013-05-09 2014-11-13 Zeenar Enterprises Pty Ltd Niacin formulation
RU2016149767A (ru) 2014-06-06 2018-07-16 Глэксосмитклайн Интеллекчуал Проперти (Но.2) Лимитед Аналоги никотинамидрибозида и фармацевтические композиции и их применение
WO2019046735A1 (en) * 2017-08-31 2019-03-07 Lonza Inc. HEALTH PROMOTING COMPOSITION AND METHODS OF USING COMPLEMENT-RELATED APPLICATIONS
CN111683649A (zh) * 2017-12-18 2020-09-18 荷兰联合利华有限公司 基于烟酰胺衍生物的局部组合物
CN111491612B (zh) 2017-12-18 2023-10-20 联合利华知识产权控股有限公司 局部组合物
CN112955115B (zh) 2018-11-02 2023-06-30 联合利华知识产权控股有限公司 生物能烟酸甘油酯、组合物和使用其的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1046055B (de) * 1956-06-18 1958-12-11 Ernst Schneider Dipl Chem Dr Verfahren zur Herstellung eines Esters mehrfach ungesaettigter hoehermolekularer Fettsaeuren
EP0182635B1 (de) * 1984-11-15 1989-05-31 Nitto Denko Corporation Zusammensetzung zur perkutanen Anwendung
GB2210789A (en) * 1987-10-10 1989-06-21 Morrison Dr Ian Donald Topical application for skin care
ATE87820T1 (de) * 1987-12-24 1993-04-15 Fujisawa Pharmaceutical Co Wirkstoff zur stimulierung des haarwuchses.
EP0643965B1 (de) * 1993-09-20 2013-05-08 Abbott Laboratories Nicotinsäure enthaltende Zusammensetzungen zur Behandlung der Hyperlipidämie
US5496827A (en) * 1994-07-15 1996-03-05 Patrick; Jay Compositions for the transdermal delivery of nutrients
EP0821587A4 (de) 1995-04-19 1999-05-19 Lipoprotein Technologies Inc Mittel, kits und verfahren zur verabreichung von antilipämischen und gegen die blutplättchen-aggregation wirkenden arzneistoffen
DK0823897T3 (da) * 1995-05-01 2004-12-06 Scarista Ltd Nicotinsyreestere og farmaceutiske præparater indeholdende disse
GB9610971D0 (en) * 1996-05-29 1996-07-31 Scotia Holdings Plc A diagnostic test for use in schizophrenia
AU7582398A (en) * 1997-05-19 1998-12-11 Rosemarie Scivoletto Composition for treating skin conditions
CA2352964C (en) * 1998-12-01 2006-10-17 University Of Kentucky Research Foundation A method for enhancing protective cellular responses to genotoxic stress in skin
US6464992B2 (en) * 2000-04-14 2002-10-15 University Of Kentucky Research Foundation Topical micronutrient delivery system and uses thereof

Also Published As

Publication number Publication date
CA2441461A1 (en) 2001-10-25
EP1274429A1 (de) 2003-01-15
US6677361B2 (en) 2004-01-13
JP4156841B2 (ja) 2008-09-24
EP1274429A4 (de) 2006-03-01
EP1274429B1 (de) 2008-05-14
WO2001078727A8 (en) 2003-11-27
US20010049382A1 (en) 2001-12-06
CN1430513A (zh) 2003-07-16
JP2004500428A (ja) 2004-01-08
HK1053607A1 (en) 2003-10-31
DE60134002D1 (de) 2008-06-26
AU5706301A (en) 2001-10-30
CN1430513B (zh) 2010-12-08
WO2001078727A1 (en) 2001-10-25
ES2302732T3 (es) 2008-08-01
MXPA02010184A (es) 2004-08-19
PT1274429E (pt) 2008-06-17
AU2001257063B2 (en) 2005-04-28
CA2441461C (en) 2007-07-10
ATE395061T1 (de) 2008-05-15

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