DK124826B - Analogifremgangsmåde til fremstilling af 1,2,4-oxadiazolforbindelser. - Google Patents

Analogifremgangsmåde til fremstilling af 1,2,4-oxadiazolforbindelser.

Info

Publication number
DK124826B
DK124826B DK139168AA DK139168A DK124826B DK 124826 B DK124826 B DK 124826B DK 139168A A DK139168A A DK 139168AA DK 139168 A DK139168 A DK 139168A DK 124826 B DK124826 B DK 124826B
Authority
DK
Denmark
Prior art keywords
preparation
oxadiazole compounds
analogous process
analogous
oxadiazole
Prior art date
Application number
DK139168AA
Other languages
Danish (da)
English (en)
Inventor
G Gregory
W Warburton
J Claisse
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of DK124826B publication Critical patent/DK124826B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
    • C07C259/14—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/24—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C07D271/07—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/28—Halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK139168AA 1967-03-31 1968-03-29 Analogifremgangsmåde til fremstilling af 1,2,4-oxadiazolforbindelser. DK124826B (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1496167 1967-03-31
US47306474A 1974-05-24 1974-05-24
US05/556,324 US4012377A (en) 1967-03-31 1975-03-07 Oxadiazole and oxadiazoline derivatives

Publications (1)

Publication Number Publication Date
DK124826B true DK124826B (da) 1972-11-27

Family

ID=27257195

Family Applications (1)

Application Number Title Priority Date Filing Date
DK139168AA DK124826B (da) 1967-03-31 1968-03-29 Analogifremgangsmåde til fremstilling af 1,2,4-oxadiazolforbindelser.

Country Status (7)

Country Link
US (1) US4012377A (de)
CH (1) CH502364A (de)
DE (1) DE1770092A1 (de)
DK (1) DK124826B (de)
FR (2) FR1579544A (de)
GB (1) GB1228142A (de)
NL (1) NL6804496A (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4212970A (en) * 1977-11-28 1980-07-15 Fuji Photo Film Co., Ltd. 2-Halomethyl-5-vinyl-1,3,4-oxadiazole compounds
DE3622296A1 (de) * 1986-07-03 1988-01-07 Basf Ag Verfahren zur herstellung von (beta)-halogenvinyl- und (beta),(beta)-dihalogenethylarylketonen
DE4041474A1 (de) * 1990-12-22 1992-06-25 Bayer Ag Verwendung von substituierten 1,2,4-oxadiazolderivaten zur bekaempfung von endoparasiten, neue substituierte 1,2,4-oxadiazolderivate und verfahren zu ihrer herstellung
DE4124151A1 (de) * 1991-07-20 1993-01-21 Bayer Ag Insektizide und akarizide pflanzenschutzmittel enthaltend substituierte 1,2,4-oxadiazolderivate
DE4232418A1 (de) * 1992-09-28 1994-03-31 Bayer Ag Verwendung von substituierten 1,2,4-Oxadiazolderivaten zur Bekämpfung von Endoparasiten, neue substituierte 1,2,4-Oxadiazolderivate und Verfahren zu ihrer Herstellung
FR2735473A1 (fr) * 1995-06-13 1996-12-20 Hoechst Schering Agrevo Sa Nouveaux derives de l'acide beta-methoxy acrylique, leur procede de preparation et leur application comme pesticides
US6043259A (en) * 1998-07-09 2000-03-28 Medicure Inc. Treatment of cardiovascular and related pathologies
EP1169322B8 (de) 1999-03-08 2006-09-13 Medicure Inc. Pyridoxal-analoge zur behandlung von störungen ausgelöst durch einen vitamin b6 mangel
AU5840200A (en) 1999-07-13 2001-01-30 Medicure Inc. Treatment of diabetes and related pathologies
EP1872797A3 (de) 1999-08-24 2008-04-02 Medicure International Inc. Behandlung kardiovaskulärer und verwandter Leiden
WO2001064692A1 (en) 2000-02-29 2001-09-07 Medicure International Inc. Cardioprotective phosphonates and malonates
US6586414B2 (en) 2000-03-28 2003-07-01 Medicure International Inc. Treatment of cerebrovascular disease
ATE364595T1 (de) 2000-07-07 2007-07-15 Medicure Int Inc Pyridoxin- und pyridoxalanaloga als cardiovasculäre therapeutika
US6897228B2 (en) 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses
US6548519B1 (en) 2001-07-06 2003-04-15 Medicure International Inc. Pyridoxine and pyridoxal analogues: novel uses
JP2008505126A (ja) * 2004-07-07 2008-02-21 メディキュア インターナショナル インコーポレイテッド 血小板凝集薬を用いる併用療法
US7459468B2 (en) * 2004-10-28 2008-12-02 Medicure International, Inc. Aryl sulfonic pyridoxines as antiplatelet agents
US20060094749A1 (en) * 2004-10-28 2006-05-04 Medicure International Inc. Substituted pyridoxines as anti-platelet agents
CA2585165A1 (en) * 2004-10-28 2006-05-18 Medicure International Inc. Dual antiplatelet/anticoagulant pyridoxine analogs
CA2632090A1 (en) * 2005-11-28 2007-05-31 Medicure International Inc. Selected dosage for the treatment of cardiovascular and related pathologies
AU2008214372A1 (en) * 2007-02-08 2008-08-14 Merck Sharp & Dohme Corp. Therapeutic agents
JP5209043B2 (ja) * 2007-05-07 2013-06-12 メルク・シャープ・アンド・ドーム・コーポレーション ガンマセクレターゼ調節剤
AU2009313524A1 (en) * 2008-11-06 2010-05-14 Merck Sharp & Dohme Corp. Gamma secretase modulators

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL291628A (de) * 1962-04-17
NL132134C (de) * 1963-03-22
US3574222A (en) * 1965-12-29 1971-04-06 Mallinckrodt Chemical Works Preparation of 5-amino-1,2,4-oxadiazoles
DE1670338A1 (de) * 1966-03-14 1972-08-10 Heyden Chem Fab Verfahren zur Herstellung von antimikrobiell wirksamen Nitrofuranderivaten
US3471621A (en) * 1966-05-02 1969-10-07 Gulf Research Development Co Method of combating nematodes with 3-cyclopropyl - 5 - dichloromethyl-1,2,4-oxadiazole
US3356684A (en) * 1966-07-28 1967-12-05 Lilly Co Eli Novel compositions for the treatment of helminthiasis
US3637707A (en) * 1970-11-24 1972-01-25 Pfizer 2-(substituted) 2-thiazolines for the control of rice blast

Also Published As

Publication number Publication date
FR8333M (de) 1970-12-14
FR1579544A (de) 1969-08-29
NL6804496A (de) 1968-10-01
US4012377A (en) 1977-03-15
GB1228142A (de) 1971-04-15
CH502364A (de) 1971-01-31
DE1770092A1 (de) 1972-01-05

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