DK124610B - Analogifremgangsmåde til fremstilling af 4,6-dichlor-Δ<4,6>-steroider af pregnanrækken. - Google Patents

Analogifremgangsmåde til fremstilling af 4,6-dichlor-Δ<4,6>-steroider af pregnanrækken.

Info

Publication number
DK124610B
DK124610B DK234568AA DK234568A DK124610B DK 124610 B DK124610 B DK 124610B DK 234568A A DK234568A A DK 234568AA DK 234568 A DK234568 A DK 234568A DK 124610 B DK124610 B DK 124610B
Authority
DK
Denmark
Prior art keywords
steroids
dichloro
preparation
analogous process
pregnane series
Prior art date
Application number
DK234568AA
Other languages
Danish (da)
English (en)
Inventor
R Wiechert
F Neumann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Priority to DK431370A priority Critical patent/DK141368B/da
Publication of DK124610B publication Critical patent/DK124610B/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK234568AA 1967-06-09 1968-05-21 Analogifremgangsmåde til fremstilling af 4,6-dichlor-Δ<4,6>-steroider af pregnanrækken. DK124610B (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK431370A DK141368B (da) 1967-06-09 1970-08-21 Analogifremgangsmåde til fremstilling af 4,6-dichlor-delta4,6-steroider af pregnanrækken.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1967SC040852 DE1643027B2 (de) 1967-06-09 1967-06-09 4,6-dichlor-delta hoch 4,6- steroide der pregnanreihe

Publications (1)

Publication Number Publication Date
DK124610B true DK124610B (da) 1972-11-06

Family

ID=7435899

Family Applications (2)

Application Number Title Priority Date Filing Date
DK234568AA DK124610B (da) 1967-06-09 1968-05-21 Analogifremgangsmåde til fremstilling af 4,6-dichlor-Δ<4,6>-steroider af pregnanrækken.
DK336171AA DK128189B (da) 1967-06-09 1971-07-08 Svangerskabsforebyggende middel på basis af 4,6-dichlor-3-oxo-Δ<4,6>-pregnadiener.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK336171AA DK128189B (da) 1967-06-09 1971-07-08 Svangerskabsforebyggende middel på basis af 4,6-dichlor-3-oxo-Δ<4,6>-pregnadiener.

Country Status (17)

Country Link
US (1) US3789087A (xx)
AT (1) AT280499B (xx)
BE (1) BE716258A (xx)
BR (1) BR6899582D0 (xx)
CH (1) CH560230A5 (xx)
CS (1) CS163723B2 (xx)
DE (1) DE1643027B2 (xx)
DK (2) DK124610B (xx)
ES (1) ES354795A1 (xx)
FI (1) FI45176C (xx)
FR (2) FR1588812A (xx)
GB (1) GB1240339A (xx)
NL (1) NL161768C (xx)
NO (1) NO129522B (xx)
PL (1) PL73566B1 (xx)
SE (1) SE341396B (xx)
YU (1) YU33977B (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2205897A1 (en) 1994-11-22 1996-05-30 Malcolm Cecil Pike Compositions and methods for contraception and for treatment of benign gynecological disorders

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB838773A (en) * 1955-07-20 1960-06-22 Farmaceutici Italia 4-substituted steroid compounds and preparation thereof
US3452058A (en) * 1958-11-13 1969-06-24 Syntex Corp 6-substituted-6-dehydro androstanes and pregnanes
GB1050218A (xx) * 1964-10-13
DE1593516C3 (de) * 1966-08-25 1975-05-15 Schering Ag, 1000 Berlin Und 4619 Bergkamen 4-Halogen-1,2 alpha; 6,7 betabismethylen-delta hoch 4-3-ketosteroide, Verfahren zu ihrer Herstellung sowie diese Steroide enthaltende Mittel
US3707537A (en) * 1969-01-08 1972-12-26 Hoffmann La Roche 4-chloro-4,6-diene-6-halo or lower alkyl steroids

Also Published As

Publication number Publication date
CS163723B2 (xx) 1975-11-07
NL161768B (nl) 1979-10-15
FI45176B (xx) 1971-12-31
YU33977B (en) 1978-09-08
FR8342M (xx) 1970-12-21
DE1643027C3 (xx) 1978-08-17
DE1643027B2 (de) 1977-12-08
NL161768C (nl) 1980-03-17
FI45176C (fi) 1972-04-10
AT280499B (de) 1970-04-10
BE716258A (xx) 1968-12-09
NL6808107A (xx) 1968-12-10
DE1643027A1 (de) 1971-04-15
DK128189B (da) 1974-03-18
PL73566B1 (xx) 1974-10-31
FR1588812A (xx) 1970-03-16
BR6899582D0 (pt) 1973-05-10
CH560230A5 (xx) 1975-03-27
US3789087A (en) 1974-01-29
YU127868A (en) 1978-02-28
NO129522B (xx) 1974-04-22
SE341396B (xx) 1971-12-27
GB1240339A (en) 1971-07-21
ES354795A1 (es) 1969-11-01

Similar Documents

Publication Publication Date Title
DK116205B (da) Analogifremgangsmåde til fremstilling af 17α-alkanoyloxy-9α-halogen-16β-methyl-11β,21-dihydroxy-Δ&lt;1,4&gt;-pregnadien-3,20-dioner.
DK121857B (da) Analogifremgangsmåde til fremstilling af 11β-alkyloxy-13β-alkylgona-1,3,5,(10)-trienderivater.
DK119878B (da) Analogifremgangsmåde til fremstilling af 2-methyl-3-carboxylsyreamido-quinoxalin-di-N-oxider-(1,4).
DK119557B (da) Analogifremgangsmåde til fremstilling af 17α-benzoyloxy-9α-fluor-16β-methyl-Δ&lt;1,4&gt;-pregnadien-11β, 21-diol-3,20-dion.
DK118877B (da) Analogifremgangsmåde til fremstilling af 3,1-benzoxazin-2-oner.
DK129234B (da) Fremgangsmåde til fremstilling af levo-1-n-butyl-2&#39;,6&#39;-pipecoloxylidid.
DK118288B (da) Analogifremgangsmåde til fremstilling af 2-halogenmethyl-3-carboxylsyreamido-quinoxalin-di-N-oxider-(1,4).
DK118246B (da) Analogifremgangsmåde til fremstilling af 2-isothiuroniummethyl-3-carboxylsyreamido-quinozalin-di-N-oxid-(1,4)-halogenider.
DK115547B (da) Fremgangsmåde til fremstilling af 17α-acyloxy-16-methyl-9α-flour-Δ&lt;1,4&gt;-pregnadien-3,20-dioner.
DK118557B (da) Fremgangsmåde til fremstilling af 17α-acyloxy-11β-hydroxy-Δ&lt;4&gt;-pregnen-3,20-dioner.
DK119166B (da) Fremgangsmåde til fremstilling af 1,4-bezodiazepinderivater.
DK124882B (da) Analogifremgangsmåde til fremstilling af 17α-acyloxy-11β-methyl-19-norpregn-4-en-3,20-dioner.
DK126936B (da) Fremgangsmåde til fremstilling af 3-oxo-13β-alkylgona-4,9,11-triener.
DK117420B (da) Analogifremgangsmåde til fremstilling af 12-oxygeneret-Δ&lt;3&gt;-A-norandrosten-2,17-dion.
DK129197B (da) Fremgangsmåde til fremstilling af 10-carbonhydridsubstituerede 5-hydroxy-13β-alkyl-Δ&lt;9(11)&gt;-gonener.
DK119976B (da) Analogifremgangsmåde til fremstilling af 18-methyl-19-nor-17α-hydroxyprogesteroner og -17-estere deraf.
DK124610B (da) Analogifremgangsmåde til fremstilling af 4,6-dichlor-Δ&lt;4,6&gt;-steroider af pregnanrækken.
DK117955B (da) Analogifremgangsmåde til fremstilling af N&lt;4&gt;-acrylerede 1-halogenbenzen-2,4-disulfonamider.
DK121372B (da) Analogifremgangsmåde til fremstilling af 17β-(1-alkoxycycloalkyloxy)-2α,3α-epithio-5α-androstaner.
DK125083B (da) Fremgangsmåde til fremstilling af 2,3-diklor-4-butyryl-fenoxyeddikesyre.
DK120994B (da) Analogifremgangsmåde til fremstilling af N,N-dimethylaminoætyl-14β-hydroksy-5β-pregn-20-en-21-karboksylater.
DK129842B (da) Fremgangsmåde til fremstilling af 3-imino-1,2-benzisothiazoliner.
DK116941B (da) Fremgangsmåde til fremstilling af 6-klor-Δ&lt;4,6&gt;-pregnadiener.
DK118402B (da) Analogifremgangsmåde til fremstilling af 11β-hydroxy-pregn-4-en-3,20-dion-[17α,16α-d]-oxazoliner.
DK122175B (da) Analogifremgangsmåde til fremstilling af 3-oxo-13β-alkyl-17α-allyl-17β-hydroxygona-4,9,11-triener.