DK123715B - Fremgangsmåde til fremstilling af 4'-demethylepipodophyllotoxin-β-D-alkylidenglucosider. - Google Patents
Fremgangsmåde til fremstilling af 4'-demethylepipodophyllotoxin-β-D-alkylidenglucosider.Info
- Publication number
- DK123715B DK123715B DK64169AA DK64169A DK123715B DK 123715 B DK123715 B DK 123715B DK 64169A A DK64169A A DK 64169AA DK 64169 A DK64169 A DK 64169A DK 123715 B DK123715 B DK 123715B
- Authority
- DK
- Denmark
- Prior art keywords
- demethylpipodophyllotoxin
- glucosides
- alkylidene
- preparation
- alkylidene glucosides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/54—Preparation of carboxylic acid anhydrides
- C07C51/56—Preparation of carboxylic acid anhydrides from organic acids, their salts, their esters or their halides, e.g. by carboxylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH284568A CH514578A (de) | 1968-02-27 | 1968-02-27 | Verfahren zur Herstellung von Glucosiden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK123715B true DK123715B (da) | 1972-07-24 |
Family
ID=4242875
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK64169AA DK123715B (da) | 1968-02-27 | 1969-02-06 | Fremgangsmåde til fremstilling af 4'-demethylepipodophyllotoxin-β-D-alkylidenglucosider. |
| DK266771AA DK128563B (da) | 1968-02-27 | 1971-06-01 | 4,6-0-Alkyliden-β-D-glucopyranoser til anvendelse som mellemprodukter ved fremstilling af terapeutisk værdifulde 4'-demethylepipodophyllotoxin-β-D-alkylidenglucosider og fremgangsmåde til fremstilling deraf. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK266771AA DK128563B (da) | 1968-02-27 | 1971-06-01 | 4,6-0-Alkyliden-β-D-glucopyranoser til anvendelse som mellemprodukter ved fremstilling af terapeutisk værdifulde 4'-demethylepipodophyllotoxin-β-D-alkylidenglucosider og fremgangsmåde til fremstilling deraf. |
Country Status (9)
| Country | Link |
|---|---|
| AT (2) | AT303270B (pt) |
| BR (1) | BR6906655D0 (pt) |
| CA (1) | CA956939A (pt) |
| CH (2) | CH514578A (pt) |
| CS (2) | CS153032B2 (pt) |
| DK (2) | DK123715B (pt) |
| FI (1) | FI48924C (pt) |
| NL (1) | NL166028C (pt) |
| SU (2) | SU406346A3 (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3374317D1 (en) * | 1982-11-26 | 1987-12-10 | Nippon Kayaku Kk | Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof |
| JPS61189230A (ja) * | 1985-02-19 | 1986-08-22 | Nippon Kayaku Co Ltd | エトポシド製剤 |
| IL77334A (en) * | 1985-12-16 | 1991-04-15 | Univ Bar Ilan | Synthesis of 9-epipodophyllotoxin glucoside derivatives and some novel intermediates therefor |
| US4904768A (en) * | 1987-08-04 | 1990-02-27 | Bristol-Myers Company | Epipodophyllotoxin glucoside 4'-phosphate derivatives |
| US4935504A (en) * | 1987-12-18 | 1990-06-19 | Bristol-Myers Company | Epipodophyllotoxin glucoside 4'-acyl derivatives |
| US5036055A (en) * | 1989-06-07 | 1991-07-30 | Bristol-Myers Company | Acylated derivatives of etoposide |
| US5066645A (en) * | 1989-09-01 | 1991-11-19 | Bristol-Myers Company | Epipodophyllotoxin altroside derivatives |
| US5463040A (en) * | 1994-06-28 | 1995-10-31 | Teva Pharmaceutical Industries, Ltd. | Method of preparing etoposide |
| US8173621B2 (en) | 2008-06-11 | 2012-05-08 | Gilead Pharmasset Llc | Nucleoside cyclicphosphates |
| NZ593648A (en) | 2008-12-23 | 2013-09-27 | Gilead Pharmasset Llc | Nucleoside phosphoramidates |
| CL2009002206A1 (es) | 2008-12-23 | 2011-08-26 | Gilead Pharmasset Llc | Compuestos derivados de pirrolo -(2-3-d]-pirimidin-7(6h)-tetrahidrofuran-2-il fosfonamidato, composicion farmaceutica; y su uso en el tratamiento de enfermedades virales. |
| EP2376514A2 (en) | 2008-12-23 | 2011-10-19 | Pharmasset, Inc. | Nucleoside analogs |
| KR101715981B1 (ko) | 2010-03-31 | 2017-03-13 | 길리애드 파마셋 엘엘씨 | 뉴클레오사이드 포스포르아미데이트 |
| MX2018011102A (es) | 2016-03-15 | 2019-01-10 | Oryzon Genomics Sa | Combinaciones de inhibidores de desmetilasa-1 especifica de lisina (lsd1) para uso en el tratamiento de tumores solidos. |
-
1968
- 1968-02-27 CH CH284568A patent/CH514578A/de not_active IP Right Cessation
-
1969
- 1969-01-31 NL NL6901619.A patent/NL166028C/xx not_active IP Right Cessation
- 1969-02-06 DK DK64169AA patent/DK123715B/da not_active IP Right Cessation
- 1969-02-06 FI FI690368A patent/FI48924C/fi active
- 1969-02-25 CA CA043,890A patent/CA956939A/en not_active Expired
- 1969-02-25 CS CS132569A patent/CS153032B2/cs unknown
- 1969-02-25 SU SU1306929A patent/SU406346A3/ru active
- 1969-02-25 AT AT188969A patent/AT303270B/de not_active IP Right Cessation
- 1969-02-25 SU SU1832411A patent/SU447886A3/ru active
- 1969-02-25 CS CS526269*A patent/CS153033B2/cs unknown
- 1969-02-25 AT AT128571A patent/AT319971B/de not_active IP Right Cessation
- 1969-02-26 BR BR206655/69A patent/BR6906655D0/pt unknown
-
1970
- 1970-10-08 CH CH1489370A patent/CH518927A/de not_active IP Right Cessation
-
1971
- 1971-06-01 DK DK266771AA patent/DK128563B/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL166028C (nl) | 1981-06-15 |
| AT303270B (de) | 1972-11-27 |
| AT319971B (de) | 1975-01-27 |
| CS153033B2 (pt) | 1974-02-22 |
| BR6906655D0 (pt) | 1973-01-09 |
| CA956939A (en) | 1974-10-29 |
| SU406346A3 (pt) | 1973-11-05 |
| NL166028B (nl) | 1981-01-15 |
| CH514578A (de) | 1971-10-31 |
| FI48924C (fi) | 1975-02-10 |
| SU447886A3 (ru) | 1974-10-25 |
| CH518927A (de) | 1972-02-15 |
| FI48924B (pt) | 1974-10-31 |
| DK128563B (da) | 1974-05-27 |
| NL6901619A (pt) | 1969-08-29 |
| CS153032B2 (pt) | 1974-02-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |