DK123104B - Analogifremgangsmåde til fremstilling af 7-(α-amino-α-phenylacetamido)-3-methyl-3-cephem-4-carboxylsyreforbindelser eller salte deraf. - Google Patents
Analogifremgangsmåde til fremstilling af 7-(α-amino-α-phenylacetamido)-3-methyl-3-cephem-4-carboxylsyreforbindelser eller salte deraf.Info
- Publication number
- DK123104B DK123104B DK160567AA DK160567A DK123104B DK 123104 B DK123104 B DK 123104B DK 160567A A DK160567A A DK 160567AA DK 160567 A DK160567 A DK 160567A DK 123104 B DK123104 B DK 123104B
- Authority
- DK
- Denmark
- Prior art keywords
- phenylacetamido
- cephem
- salts
- amino
- methyl
- Prior art date
Links
- ZAIPMKNFIOOWCQ-QKFMDRJYSA-N (6r)-7-[(2-amino-2-phenylacetyl)amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical class C1([C@@H]2N(C1=O)C(=C(CS2)C)C(O)=O)NC(=O)C(N)C1=CC=CC=C1 ZAIPMKNFIOOWCQ-QKFMDRJYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57922266A | 1966-09-14 | 1966-09-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK123104B true DK123104B (da) | 1972-05-15 |
Family
ID=24316060
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK160567AA DK123104B (da) | 1966-09-14 | 1967-03-28 | Analogifremgangsmåde til fremstilling af 7-(α-amino-α-phenylacetamido)-3-methyl-3-cephem-4-carboxylsyreforbindelser eller salte deraf. |
Country Status (11)
Country | Link |
---|---|
US (1) | US3507861A (da) |
JP (1) | JPS4921155B1 (da) |
BE (1) | BE696026A (da) |
CH (1) | CH501011A (da) |
DE (1) | DE1670625C3 (da) |
DK (1) | DK123104B (da) |
ES (1) | ES338498A1 (da) |
FR (1) | FR6294M (da) |
NL (1) | NL141515B (da) |
NO (1) | NO133804C (da) |
SE (1) | SE359841B (da) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE29164E (en) * | 1967-09-05 | 1977-03-29 | Bristol-Myers Company | 7-Amino-cephalosporanic and decephalosporanic acid derivatives |
US3852282A (en) * | 1969-04-01 | 1974-12-03 | Squibb & Sons Inc | Certain 2-substituted cephalosporins |
GB1332306A (en) * | 1969-12-23 | 1973-10-03 | Glaxo Lab Ltd | Antibiotics |
US4000129A (en) * | 1970-02-18 | 1976-12-28 | Koninklijke Nederlandsche Gist-En Spiritusfabriek N.V. | 6-aminopenicillanic acid sulfoxide silyl esters |
US3668201A (en) * | 1970-02-24 | 1972-06-06 | Lilly Co Eli | Cepham compounds |
US3668202A (en) * | 1970-02-24 | 1972-06-06 | Lilly Co Eli | Process for preparing cepham compounds |
US3676434A (en) * | 1970-07-29 | 1972-07-11 | Lilly Co Eli | Cephalosporin salts |
US3714146A (en) * | 1970-10-05 | 1973-01-30 | Bristol Myers Co | Novel syntheses of cephalexin and intermediates therefor |
CA972362A (en) * | 1970-10-12 | 1975-08-05 | Hirotomo Masuya | Penicillins and cephalosporins |
US4175125A (en) * | 1971-12-27 | 1979-11-20 | Eli Lilly And Company | Method for treating methicillin resistant staphylococcus aureus |
JPS551272B2 (da) * | 1972-04-14 | 1980-01-12 | ||
US3923795A (en) * | 1972-06-19 | 1975-12-02 | Lilly Co Eli | 2-Alkoxycephalosporins |
US4056676A (en) * | 1973-03-14 | 1977-11-01 | Eli Lilly And Company | Halogenated phenylthioacetamido cephalosporins |
AR205537A1 (es) * | 1973-05-10 | 1976-05-14 | Fujisawa Pharmaceutical Co | Procedimiento para la preparacion de derivados de acido 7-substituido fenilglicinamido - 3 - substituido - 3 - cefem - 4 - carboxilicos |
DE2355078A1 (de) * | 1973-11-03 | 1975-05-07 | Bayer Ag | Verfahren zur herstellung von 7-amino-delta hoch 3-cephem-derivaten |
US4063019A (en) | 1976-03-30 | 1977-12-13 | E. R. Squibb & Sons, Inc. | [[[(2,4-Dioxo-1-imidazolidinyl)amino]carbonyl]amino]-acetylcephalosporin derivatives |
US4946838A (en) * | 1981-07-13 | 1990-08-07 | E. R. Squibb & Sons, Inc. | Crystalline anhydrous aztreonam |
ZA84584B (en) * | 1983-01-28 | 1984-09-26 | Bristol Myers Co | Substituted vinyl cephalosporins |
US4520022A (en) * | 1983-01-28 | 1985-05-28 | Bristol-Myers Company | Substituted vinyl cephalosporins |
US4600773A (en) * | 1983-12-01 | 1986-07-15 | Eli Lilly And Company | Crystalline cephalexin hydrochloride monohydrate |
US4775751A (en) * | 1985-06-03 | 1988-10-04 | Eli Lilly & Company | Process for cephalexin hydrochloride alcoholates |
US5908929A (en) * | 1996-12-05 | 1999-06-01 | Vitara Chemicals Limited | Process for the manufacture of the antibiotic 7-(D-α-amino-α-phenylacetamido)-3-methyl-3-cephem-4-carboxylic acid (cephalexin) and pharmaceutically acceptable salts thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3131184A (en) * | 1961-12-27 | 1964-04-28 | Smith Kline French Lab | Derivatives of 7-aminocephalosporanic acid |
US3167550A (en) * | 1962-11-13 | 1965-01-26 | Smith Kline French Lab | Derivatives of 7-aminocephalosporanic acid |
US3324118A (en) * | 1965-12-27 | 1967-06-06 | Lilly Co Eli | Phenalkylmercaptomethyl cephalosporins |
-
1966
- 1966-09-14 US US579222A patent/US3507861A/en not_active Expired - Lifetime
-
1967
- 1967-03-10 NO NO167231A patent/NO133804C/no unknown
- 1967-03-22 SE SE03992/67A patent/SE359841B/xx unknown
- 1967-03-23 BE BE696026D patent/BE696026A/xx not_active IP Right Cessation
- 1967-03-23 FR FR99908A patent/FR6294M/fr not_active Expired
- 1967-03-23 NL NL676704294A patent/NL141515B/xx not_active IP Right Cessation
- 1967-03-27 ES ES338498A patent/ES338498A1/es not_active Expired
- 1967-03-28 DE DE1670625A patent/DE1670625C3/de not_active Expired
- 1967-03-28 DK DK160567AA patent/DK123104B/da not_active IP Right Cessation
- 1967-03-28 CH CH428767A patent/CH501011A/de not_active IP Right Cessation
-
1971
- 1971-03-27 JP JP46018322A patent/JPS4921155B1/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
NL6704294A (da) | 1968-03-15 |
NO133804C (da) | 1976-06-30 |
NO133804B (da) | 1976-03-22 |
BE696026A (da) | 1967-09-25 |
CH501011A (de) | 1970-12-31 |
NL141515B (nl) | 1974-03-15 |
DE1670625B2 (de) | 1974-10-24 |
JPS4921155B1 (da) | 1974-05-30 |
DE1670625A1 (de) | 1970-08-06 |
SE359841B (da) | 1973-09-10 |
ES338498A1 (es) | 1968-04-01 |
FR6294M (da) | 1968-09-09 |
US3507861A (en) | 1970-04-21 |
DE1670625C3 (de) | 1975-05-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUP | Patent expired |