DK123094B - Fremgangsmåde til fremstilling af N<α(A1)>,N<ɛ(B29)>-bis-(tert.butyloxycarbonyl)-insulin. - Google Patents

Fremgangsmåde til fremstilling af N<α(A1)>,N<ɛ(B29)>-bis-(tert.butyloxycarbonyl)-insulin.

Info

Publication number
DK123094B
DK123094B DK511369AA DK511369A DK123094B DK 123094 B DK123094 B DK 123094B DK 511369A A DK511369A A DK 511369AA DK 511369 A DK511369 A DK 511369A DK 123094 B DK123094 B DK 123094B
Authority
DK
Denmark
Prior art keywords
butyloxycarbonyl
insulin
tert
bis
preparation
Prior art date
Application number
DK511369AA
Other languages
English (en)
Inventor
A Mager
A Baender
H Schoene
R Geiger
W Pfaff
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK123094B publication Critical patent/DK123094B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK511369AA 1968-09-28 1969-09-25 Fremgangsmåde til fremstilling af N<α(A1)>,N<ɛ(B29)>-bis-(tert.butyloxycarbonyl)-insulin. DK123094B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1793517A DE1793517C3 (de) 1968-09-28 1968-09-28 N(Al),N(B29>Bis-(tert.-butyloxycarbonyl)-insulin und Verfahren zu seiner Herstellung

Publications (1)

Publication Number Publication Date
DK123094B true DK123094B (da) 1972-05-15

Family

ID=5707736

Family Applications (1)

Application Number Title Priority Date Filing Date
DK511369AA DK123094B (da) 1968-09-28 1969-09-25 Fremgangsmåde til fremstilling af N<α(A1)>,N<ɛ(B29)>-bis-(tert.butyloxycarbonyl)-insulin.

Country Status (10)

Country Link
US (1) US3684791A (da)
AT (1) AT290032B (da)
BE (1) BE739511A (da)
CH (1) CH530207A (da)
DE (1) DE1793517C3 (da)
DK (1) DK123094B (da)
FR (1) FR2019135A1 (da)
GB (1) GB1223350A (da)
NL (1) NL159089B (da)
SE (1) SE362872B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3934008A (en) * 1968-08-23 1976-01-20 Ciba-Geigy Corporation N-acyl and desamino human calcitonin and analogs thereof
GB1381274A (en) * 1971-01-28 1975-01-22 Nat Res Dev Insulin derivatives
GB1381273A (en) * 1971-01-28 1975-01-22 Nat Res Dev Insulin derivatives
US3864325A (en) * 1971-11-18 1975-02-04 Nat Res Dev (N{HU Al{b , N{HU Bl{b , N{HU B29{B , carbamoyl)-(O{HU A14{B , O{HU B16{B , O{HU B26{B aryl) insulin derivatives
SV1998000125A (es) 1997-10-24 1999-05-24 Lilly Co Eli Composiciones de insulina insoluble ref. x-11232
US6531448B1 (en) 1997-12-23 2003-03-11 Eli Lilly And Company Insoluble compositions for controlling blood glucose
US7040519B2 (en) * 2003-06-12 2006-05-09 Jere F. Irwin Thermoformable web support apparatus and support device for a heated plastic sheet
US9050370B2 (en) 2009-01-28 2015-06-09 Smartcells, Inc. Conjugate based systems for controlled drug delivery
WO2010088268A1 (en) 2009-01-28 2010-08-05 Smartcells, Inc. Exogenously triggered controlled release materials and uses thereof
BRPI1007466A2 (pt) 2009-01-28 2018-06-12 Smartcells Inc conjugado de insulina cristalina, formulação de liberação prolongada, e, sistema de distribuição de bomba
US8940690B2 (en) 2009-01-28 2015-01-27 National Institutes Of Health (Nih) Synthetic conjugates and uses thereof
EP2408470A4 (en) 2009-03-20 2012-08-29 Smartcells Inc SOLUBLE NONDEPOT INSULIN CONJUGATE AND ITS USE
WO2010107519A1 (en) 2009-03-20 2010-09-23 Smartcells, Inc. Terminally-functionalized conjugates and uses thereof
AU2011282977A1 (en) 2010-07-28 2013-02-21 Smartcells, Inc. Drug-ligand conjugates, synthesis thereof, and intermediates thereto
WO2012015692A2 (en) 2010-07-28 2012-02-02 Smartcells, Inc. Recombinantly expressed insulin polypeptides and uses thereof
CA2805902A1 (en) 2010-07-28 2012-02-02 Smartcells, Inc. Recombinant lectins, binding-site modified lectins and uses thereof
US9884125B2 (en) 2013-10-04 2018-02-06 Merck Sharp & Dohme Corp. Glucose-responsive insulin conjugates
FR3120445B1 (fr) 2021-03-08 2023-02-10 Aryballe Procédé de caractérisation d’un analyte présent dans un échantillon gazeux contenant au moins une espèce chimique parasite

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3528960A (en) * 1968-10-07 1970-09-15 Lilly Co Eli N-carboxyaroyl insulins

Also Published As

Publication number Publication date
NL159089B (nl) 1979-01-15
US3684791A (en) 1972-08-15
DE1793517A1 (de) 1972-03-02
SE362872B (da) 1973-12-27
NL6914400A (da) 1970-04-01
GB1223350A (en) 1971-02-24
AT290032B (de) 1971-05-10
CH530207A (de) 1972-11-15
DE1793517C3 (de) 1974-12-05
DE1793517B2 (de) 1974-05-09
FR2019135A1 (da) 1970-06-26
BE739511A (da) 1970-03-31

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