DK121369B - Fremgangsmåde til fremstilling af 3-oxo-Δ<4>-steroider, 3-oxo-Δ<5(10)>-steroider eller enolethere deraf. - Google Patents

Fremgangsmåde til fremstilling af 3-oxo-Δ<4>-steroider, 3-oxo-Δ<5(10)>-steroider eller enolethere deraf.

Info

Publication number
DK121369B
DK121369B DK375361AA DK375361A DK121369B DK 121369 B DK121369 B DK 121369B DK 375361A A DK375361A A DK 375361AA DK 375361 A DK375361 A DK 375361A DK 121369 B DK121369 B DK 121369B
Authority
DK
Denmark
Prior art keywords
steroids
oxo
preparation
enol ethers
enol
Prior art date
Application number
DK375361AA
Other languages
Danish (da)
English (en)
Inventor
G Hughes
H Smith
Original Assignee
H Smith
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Smith filed Critical H Smith
Publication of DK121369B publication Critical patent/DK121369B/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J63/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • C07J1/0088Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096Alkynyl derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005Ketals
    • C07J21/008Ketals at position 17
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J3/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DK375361AA 1960-09-22 1961-09-21 Fremgangsmåde til fremstilling af 3-oxo-Δ<4>-steroider, 3-oxo-Δ<5(10)>-steroider eller enolethere deraf. DK121369B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB32670/60A GB1010053A (en) 1960-09-22 1960-09-22 13-alkyl 5,10-ethylenic steroid 3-ketones and their enol ethers

Publications (1)

Publication Number Publication Date
DK121369B true DK121369B (da) 1971-10-11

Family

ID=10342246

Family Applications (2)

Application Number Title Priority Date Filing Date
DK375361AA DK121369B (da) 1960-09-22 1961-09-21 Fremgangsmåde til fremstilling af 3-oxo-Δ<4>-steroider, 3-oxo-Δ<5(10)>-steroider eller enolethere deraf.
DK283471AA DK125991B (da) 1960-09-22 1971-06-10 Enolethere af 3-oxo-Δ<4>- eller 3-oxo-Δ<5(10)>- steroider til anvendelse som mellemprodukter ved syntesen af 3-oxo-Δ<4>- eller 3-oxo-Δ<5(10)>-steroider.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK283471AA DK125991B (da) 1960-09-22 1971-06-10 Enolethere af 3-oxo-Δ<4>- eller 3-oxo-Δ<5(10)>- steroider til anvendelse som mellemprodukter ved syntesen af 3-oxo-Δ<4>- eller 3-oxo-Δ<5(10)>-steroider.

Country Status (8)

Country Link
AT (2) AT282083B (de)
CH (3) CH421096A (de)
DE (2) DE1443124A1 (de)
DK (2) DK121369B (de)
FR (1) FR1393968A (de)
GB (1) GB1010053A (de)
IT (1) IT1061739B (de)
SE (3) SE354064B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012110947A1 (en) 2011-02-17 2012-08-23 Lupin Limited An improved process for preparation of levonorgestrel

Also Published As

Publication number Publication date
FR1393968A (fr) 1965-04-02
DE1793659A1 (de) 1972-01-13
DE1443124A1 (de) 1968-10-24
SE307787B (de) 1969-01-20
AT282083B (de) 1970-06-10
DE1793659B2 (de) 1974-08-15
CH430706A (de) 1967-02-28
SE334878B (de) 1971-05-10
IT1061739B (it) 1983-04-30
DE1793659C3 (de) 1975-03-27
DK125991B (da) 1973-05-28
GB1010053A (en) 1965-11-17
SE354064B (de) 1973-02-26
AT268544B (de) 1969-02-10
CH427785A (de) 1967-01-15
CH421096A (de) 1966-09-30

Similar Documents

Publication Publication Date Title
DK105157C (da) Fremgangsmåde til fremstilling af Δ&lt;1,4&gt;-16-α-metylsteroider.
DK104566C (da) Fremgangsmåde til fremstilling af 3-enolætere af 3-okso-Δ&lt;4&gt;-6-aminometylsteroider.
DK120701B (da) Analogifremgangsmåde til fremstilling af terapeutisk virksomme 17β-tetrahydropyranylethere af Δ&lt;1,3,5(10)&gt;-østratrien-3-ol-eller 3-ethere eller 3-estere deraf.
DK121369B (da) Fremgangsmåde til fremstilling af 3-oxo-Δ&lt;4&gt;-steroider, 3-oxo-Δ&lt;5(10)&gt;-steroider eller enolethere deraf.
DK104346C (da) Fremgangsmåde til fremstilling af 6-metylen-3-oxo-Δ&lt;4&gt;-steroider.
DK105065C (da) Fremgangsmåde til fremstilling af 16α,17α-acetaler eller -ketaler af 3-oxo-16α,17α-dihydroxy-19-nor-4-pregnener eller 3-oxo-16α,17α-dihydroxy-19-nor-5(10)-pregnener.
DK102858C (da) Fremgangsmåde til fremstilling af 3-oxo-17β-hydroxy-10β-allyl-Δ&lt;4,9(11)&gt;-estradien eller dets estere.
DK100229C (da) Fremgangsmåde til fremstilling af 3-keto-Δ&lt;4&gt;-6α-trifluormethyl-pregnener eller disses 3-enolethere.
DK104786C (da) Fremgangsmåde til fremstilling af 6-methyl-3-oxo-Δ&lt;4,6&gt;-steroider.
DK100421C (da) Fremgangsmåde til fremstilling af 3,11,20-triketo-6-fluor-16α-methyl-21-hydroxy-Δ&lt;4&gt;-pregnen eller 21-estere deraf.
DK100227C (da) Fremgangsmåde til fremstilling af 3-enolætere af 6-hydroxymetyl-3-oxo-Δ&lt;4&gt;-steroider.
DK101239C (da) Fremgangsmåde til fremstilling af 3-enolætere af 6-formyl-3-okso-Δ&lt;4&gt;-steroider.
DK113921B (da) Fremgangsmåde til fremstilling af Δ&lt;1,3,5,(10),8,14&gt;-17-hydroxy-steroid- eller -D-homosteroid-forbindelser eller 17-estere deraf.
DK119159B (da) Fremgangsmåde til fremstilling af Δ&lt;1,3,5&gt;-steroid-forbindelser.
DK99307C (da) Fremgangsmåde til fremstilling af 3-oxo-10β-methyl-13β-n-propyl-Δ&lt;4,9(11)&gt;-steroider.
DK105529C (da) Fremgangsmåde til fremstilling af 3-hydroxy-, 3-alkoxy- eller 3-acyloxy-Δ&lt;1,3,5(10)&gt;-steroid- eller -D-homosteroidforbindelser.
DK114827B (da) Fremgangsmåde til fremstilling af 5-keto-11-hydroxy-17β-acyloxy-Δ&lt;9&gt;-des-A-estren eller 5,11-diketo-17β-acyloxy-Δ&lt;9&gt;-des-A-estren.
DK114620B (da) Fremgangsmåde til fremstilling af 6-chlor-16α-methyl-Δ&lt;4,6&gt;-pregnadien-17α-ol-3,20-dion eller dens 17-estere.
DK104170C (da) Fremgangsmåde til fremstilling af 3-alkoxy- eller 3-aralkoxy-16-amino-Δ&lt;3,5&gt;-pregnadien-17α-ol-20-oner, eller 16-amino-Δ&lt;4&gt;-pregnen-17α-ol-3,20-dioner.
DK104623C (da) Fremgangsmåde til fremstilling af 3-keto-17β-hydroxy-19-nor-Δ&lt;4&gt;-9β,10α-androstener eller estere eller ethere deraf.
DK100944C (da) Fremgangsmåde til fremstilling af 4-flour-3-oxo-Δ&lt;4&gt;-eller -Δ&lt;1,4&gt;-steroider.
DK100109C (da) Fremgangsmåde til fremstilling af 3-keto-Δ&lt;4,9(10)&gt;-19-nor-steroider.
DK98005C (da) Fremgangsmåde til fremstilling af 3α,11β-dihydroxy-20,20-bis-(nitratomethyl)-5β-pregnan eller dets 3α-estere.
DK99632C (da) Fremgangsmåde til fremstilling af 3,20-dioxo-16α-methyl-9-α-fluor-11β,21-dihydroxy-Δ&lt;1,4&gt;-pregnadien eller estere heraf.
DK99457C (da) Fremgangsmåde til fremstilling af 20,21-dihydroxy-3,11-dioxo-20-hydroxymethyl-Δ&lt;4&gt;-pregnen eller estere deraf.