DK1212410T3 - DNA kodende for den humane serinprotease EOS - Google Patents

DNA kodende for den humane serinprotease EOS

Info

Publication number
DK1212410T3
DK1212410T3 DK00957639T DK00957639T DK1212410T3 DK 1212410 T3 DK1212410 T3 DK 1212410T3 DK 00957639 T DK00957639 T DK 00957639T DK 00957639 T DK00957639 T DK 00957639T DK 1212410 T3 DK1212410 T3 DK 1212410T3
Authority
DK
Denmark
Prior art keywords
protease
protease eos
serine protease
eos
platelets
Prior art date
Application number
DK00957639T
Other languages
Danish (da)
English (en)
Inventor
Andrew L Darrow
Patricia Andrade-Gordon
Cailin Chen
Jensen Qi
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of DK1212410T3 publication Critical patent/DK1212410T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/04—Fusion polypeptide containing a localisation/targetting motif containing an ER retention signal such as a C-terminal HDEL motif
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C07K2319/42—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a HA(hemagglutinin)-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Dermatology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)
DK00957639T 1999-08-31 2000-08-18 DNA kodende for den humane serinprotease EOS DK1212410T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/387,375 US6485957B1 (en) 1999-04-30 1999-08-31 DNA encoding the human serine protease EOS

Publications (1)

Publication Number Publication Date
DK1212410T3 true DK1212410T3 (da) 2006-09-04

Family

ID=23529600

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00957639T DK1212410T3 (da) 1999-08-31 2000-08-18 DNA kodende for den humane serinprotease EOS

Country Status (10)

Country Link
US (6) US6485957B1 (ja)
EP (1) EP1212410B1 (ja)
JP (1) JP2003529329A (ja)
AT (1) ATE327323T1 (ja)
AU (1) AU781420B2 (ja)
CA (1) CA2383601A1 (ja)
DE (1) DE60028216T2 (ja)
DK (1) DK1212410T3 (ja)
ES (1) ES2264938T3 (ja)
WO (1) WO2001016290A2 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6485957B1 (en) * 1999-04-30 2002-11-26 Ortho-Mcneil Pharmaceutical, Inc. DNA encoding the human serine protease EOS
ATE317399T1 (de) * 2000-06-23 2006-02-15 Regulierung der menschlichen prostasin-änhlichen serine protease
JP4159878B2 (ja) * 2001-02-01 2008-10-01 エフ．ホフマン−ラ ロシュ アーゲー 組換えトリプシンの製造方法
US7666627B2 (en) * 2002-08-08 2010-02-23 Targetex Kft. Folded recombinant catalytic fragments of multidomain serine proteases, preparation and uses thereof
AU2002951912A0 (en) * 2002-10-08 2002-10-24 Unisearch Limited Tryptase polypeptide and uses thereof
WO2006063462A1 (en) * 2004-12-13 2006-06-22 Alethia Biotherapeutics Inc. Polynucleotides and polypeptide sequences involved in the process of bone remodeling
KR20090121753A (ko) * 2008-05-23 2009-11-26 주식회사 한국번디 석션파이프 어셈블리 및 그의 제조방법
JP2022524103A (ja) 2019-03-08 2022-04-27 メビオン・メディカル・システムズ・インコーポレーテッド カラム別の放射線の照射およびそのための治療計画の生成
AU2020272127B2 (en) 2019-04-12 2022-12-08 Ecolab Usa Inc. Antimicrobial multi-purpose cleaner and methods of making and using the same
US12094740B2 (en) 2021-03-25 2024-09-17 Applied Materials, Inc. Automated dry-in dry-out dual side polishing of silicon substrates with integrated spin rinse dry and metrology

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US94955A (en) 1869-09-21 Improved compound for emery-wheels and oil-stones
US5763257A (en) * 1984-05-29 1998-06-09 Genencor International, Inc. Modified subtilisins having amino acid alterations
PT86864B (pt) 1987-02-27 1992-05-29 Gist Brocades Nv Processo para clonagem molecular e expressao de genes que codificam para enzimas proteoliticas
US5278062A (en) 1987-04-03 1994-01-11 Amgen Proteolytic enzymes
US5200340A (en) 1987-05-22 1993-04-06 Zymogenetics, Inc. Thrombin-activated tissue plasminogen activators
US5270178A (en) 1990-02-23 1993-12-14 Eli Lilly And Company Vectors and compounds for expression of zymogen forms of human protein C
US5326700A (en) 1990-11-06 1994-07-05 Eli Lilly And Company DNA sequences encoding t-PA derivatives with cleavable sites
CA2153254C (en) 1993-01-15 2002-05-21 Edward R. Lavallie Cloning of enterokinase and method of use
DK72593D0 (da) * 1993-06-18 1993-06-18 Symbicom Ab Rekombinant protein
DE59711957D1 (de) 1996-06-11 2004-10-28 Roche Diagnostics Gmbh Rekombinante blutgerinnungsproteasen
WO1998036054A1 (en) * 1997-02-13 1998-08-20 Amrad Operations Pty. Ltd. Novel molecules
US6165771A (en) * 1997-06-10 2000-12-26 Smithkline Beecham, P.L.C. Compounds
CA2303834A1 (en) * 1997-09-17 1999-03-25 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US6485957B1 (en) 1999-04-30 2002-11-26 Ortho-Mcneil Pharmaceutical, Inc. DNA encoding the human serine protease EOS
CA2385703A1 (en) * 1999-10-07 2001-04-12 Human Genome Sciences, Inc. Plasminogen-like polynucleotides, polypeptides, and antibodies
ATE317399T1 (de) * 2000-06-23 2006-02-15 Regulierung der menschlichen prostasin-änhlichen serine protease

Also Published As

Publication number Publication date
US20020110895A1 (en) 2002-08-15
AU781420B2 (en) 2005-05-19
US6485957B1 (en) 2002-11-26
US20070218026A1 (en) 2007-09-20
DE60028216T2 (de) 2007-05-10
ES2264938T3 (es) 2007-02-01
EP1212410A4 (en) 2004-03-17
EP1212410B1 (en) 2006-05-24
US20040170973A1 (en) 2004-09-02
CA2383601A1 (en) 2001-03-08
US6747134B2 (en) 2004-06-08
AU6922800A (en) 2001-03-26
US20020142446A1 (en) 2002-10-03
WO2001016290A3 (en) 2002-01-24
DE60028216D1 (de) 2006-06-29
US6846920B2 (en) 2005-01-25
US6806059B2 (en) 2004-10-19
EP1212410A2 (en) 2002-06-12
US20020142447A1 (en) 2002-10-03
WO2001016290A2 (en) 2001-03-08
JP2003529329A (ja) 2003-10-07
ATE327323T1 (de) 2006-06-15

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