DK120770B - Fremgangsmåde til fremstilling af gentamycin og BA-3 fraktion A og B eller salte, reaktionsprodukter med bisulfitadditionsforbindelser af aldehyder eller ketoner, N-acylderivater, O-acylderivater eller Schiffske baser heraf. - Google Patents

Fremgangsmåde til fremstilling af gentamycin og BA-3 fraktion A og B eller salte, reaktionsprodukter med bisulfitadditionsforbindelser af aldehyder eller ketoner, N-acylderivater, O-acylderivater eller Schiffske baser heraf.

Info

Publication number
DK120770B
DK120770B DK487662AA DK487662A DK120770B DK 120770 B DK120770 B DK 120770B DK 487662A A DK487662A A DK 487662AA DK 487662 A DK487662 A DK 487662A DK 120770 B DK120770 B DK 120770B
Authority
DK
Denmark
Prior art keywords
acyl derivatives
gentamycin
aldehydes
ketones
fractions
Prior art date
Application number
DK487662AA
Other languages
English (en)
Inventor
G Luedemann
M Weinstein
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US211153A external-priority patent/US3091572A/en
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of DK120770B publication Critical patent/DK120770B/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C07H15/236Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/46Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
    • C12P19/48Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin
    • C12P19/485Having two saccharide radicals bound through only oxygen to non-adjacent ring carbons of the cyclohexyl radical, e.g. gentamycin, kanamycin, sisomycin, verdamycin, mutamycin, tobramycin, nebramycin, antibiotics 66-40B, 66-40D, XK-62-2, 66-40, G-418, G-52
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/29Micromonospora

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK487662AA 1961-11-14 1962-11-13 Fremgangsmåde til fremstilling af gentamycin og BA-3 fraktion A og B eller salte, reaktionsprodukter med bisulfitadditionsforbindelser af aldehyder eller ketoner, N-acylderivater, O-acylderivater eller Schiffske baser heraf. DK120770B (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15226261A 1961-11-14 1961-11-14
US19841462A 1962-05-23 1962-05-23
US211153A US3091572A (en) 1962-07-16 1962-07-16 Gentamycin and method of production

Publications (1)

Publication Number Publication Date
DK120770B true DK120770B (da) 1971-07-12

Family

ID=27387225

Family Applications (1)

Application Number Title Priority Date Filing Date
DK487662AA DK120770B (da) 1961-11-14 1962-11-13 Fremgangsmåde til fremstilling af gentamycin og BA-3 fraktion A og B eller salte, reaktionsprodukter med bisulfitadditionsforbindelser af aldehyder eller ketoner, N-acylderivater, O-acylderivater eller Schiffske baser heraf.

Country Status (9)

Country Link
AT (1) AT246917B (da)
BE (1) BE624816A (da)
CA (2) CA922250A (da)
CH (1) CH428098A (da)
CY (1) CY357A (da)
DE (1) DE1218660B (da)
DK (1) DK120770B (da)
GB (1) GB1021401A (da)
NO (1) NO118368B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR128F (da) * 1962-04-02

Also Published As

Publication number Publication date
CA933153A (en) 1973-09-04
CA922250A (en) 1973-03-06
CH428098A (de) 1967-01-15
BE624816A (da) 1963-05-14
GB1021401A (en) 1966-03-02
NO118368B (da) 1969-12-22
AT246917B (de) 1966-05-10
DE1218660B (de) 1966-06-08
CY357A (en) 1966-12-30

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