DK119086A - Fremgangsmaade til fremstilling af oligonucleotider - Google Patents

Fremgangsmaade til fremstilling af oligonucleotider Download PDF

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Publication number
DK119086A
DK119086A DK119086A DK119086A DK119086A DK 119086 A DK119086 A DK 119086A DK 119086 A DK119086 A DK 119086A DK 119086 A DK119086 A DK 119086A DK 119086 A DK119086 A DK 119086A
Authority
DK
Denmark
Prior art keywords
oligonucleotides
procedure
preparation
Prior art date
Application number
DK119086A
Other languages
English (en)
Other versions
DK119086D0 (da
Inventor
Nanibhushan Dattagupta
William Knowles
Original Assignee
Molecular Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/712,481 external-priority patent/US4808520A/en
Application filed by Molecular Diagnostics Inc filed Critical Molecular Diagnostics Inc
Publication of DK119086D0 publication Critical patent/DK119086D0/da
Publication of DK119086A publication Critical patent/DK119086A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • C07H19/10Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK119086A 1985-03-15 1986-03-14 Fremgangsmaade til fremstilling af oligonucleotider DK119086A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/712,481 US4808520A (en) 1985-03-15 1985-03-15 Labelling of oligonucleotides
US80887185A 1985-12-18 1985-12-18

Publications (2)

Publication Number Publication Date
DK119086D0 DK119086D0 (da) 1986-03-14
DK119086A true DK119086A (da) 1986-09-16

Family

ID=27108843

Family Applications (1)

Application Number Title Priority Date Filing Date
DK119086A DK119086A (da) 1985-03-15 1986-03-14 Fremgangsmaade til fremstilling af oligonucleotider

Country Status (10)

Country Link
EP (1) EP0194545B1 (da)
AU (1) AU592777B2 (da)
CA (1) CA1278755C (da)
DE (1) DE3667292D1 (da)
DK (1) DK119086A (da)
ES (1) ES8705920A1 (da)
FI (1) FI861039A (da)
IL (1) IL78123A (da)
NO (1) NO860710L (da)
NZ (1) NZ215453A (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1284931C (en) * 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
US5604099A (en) * 1986-03-13 1997-02-18 Hoffmann-La Roche Inc. Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
AU622104B2 (en) * 1987-03-11 1992-04-02 Sangtec Molecular Diagnostics Ab Method of assaying of nucleic acids, a reagent combination and kit therefore
US4994368A (en) * 1987-07-23 1991-02-19 Syntex (U.S.A.) Inc. Amplification method for polynucleotide assays
US5273879A (en) * 1987-07-23 1993-12-28 Syntex (U.S.A.) Inc. Amplification method for polynucleotide assays
CA1325761C (en) * 1987-12-25 1994-01-04 Takanori Oka Method of detecting an intended nucleic acid in a sample
US5047523A (en) * 1988-08-02 1991-09-10 Ortho Diagnostic Systems Inc. Nucleic acid probe for detection of neisseria gonorrhoea
US4879214A (en) * 1988-11-15 1989-11-07 E. I. Du Pont De Nemours And Company Differentiation of nucleic acid segments on the basis of nucleotide differences
US5324829A (en) * 1988-12-16 1994-06-28 Ortho Diagnostic Systems, Inc. High specific activity nucleic acid probes having target recognition and signal generating moieties
GR1000347B (el) * 1988-12-21 1992-06-25 Ortho Diagnostic Systems Inc Μεθοδος παραγωγης νουκλεοτιδικων ανιχνευτων χρησιμοποιωντας ενα συμπληρωμα γεφυρωσεως.
JPH03123500A (ja) * 1989-10-06 1991-05-27 Canon Inc 核酸の分別方法
CA2080305A1 (en) 1991-10-11 1993-04-12 Linda M. Western Method for producing a polynucleotide for use in single primer amplification and phosphorothioate-containing oligonucleotides as primers in nucleic acid amplification
US5612199A (en) * 1991-10-11 1997-03-18 Behringwerke Ag Method for producing a polynucleotide for use in single primer amplification
GB9201073D0 (en) * 1992-01-18 1992-03-11 Cytocell Ltd Chromosome hybridisation methods
DK0652973T3 (da) * 1992-07-31 1997-09-15 Behringwerke Ag Fremgangsmåde til indføring af definerede sekvenser ved 3-enden af polynukleotider
US6294323B1 (en) 1993-04-14 2001-09-25 Behringwerke Ag Self initiating single primer amplification of nucleic acids

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1254525A (en) * 1983-04-13 1989-05-23 Christine L. Brakel Kit for terminally chemically labeling dna
DE3441369A1 (de) * 1984-11-13 1986-05-22 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von hydroxymethylen-alkoxyessigsaeureestern
US4734363A (en) * 1984-11-27 1988-03-29 Molecular Diagnostics, Inc. Large scale production of DNA probes
CA1272443A (en) * 1985-02-22 1990-08-07 Nanibhushan Dattagupta Solution-phase dual hybridization assay for detecting polynucleotide sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
DK171161B1 (da) * 1985-03-28 1996-07-08 Hoffmann La Roche Fremgangsmåde til påvisning af forekomst eller fravær af mindst én specifik nukleinsyresekvens i en prøve eller til skelnen mellem to forskellige nukleinsyresekvenser i denne prøve

Also Published As

Publication number Publication date
EP0194545A3 (en) 1988-01-13
NO860710L (no) 1986-09-16
ES8705920A1 (es) 1987-05-16
EP0194545B1 (en) 1989-12-06
ES553034A0 (es) 1987-05-16
AU592777B2 (en) 1990-01-25
DK119086D0 (da) 1986-03-14
EP0194545A2 (en) 1986-09-17
FI861039A (fi) 1986-09-16
IL78123A0 (en) 1986-07-31
IL78123A (en) 1990-02-09
NZ215453A (en) 1989-06-28
AU5443186A (en) 1986-09-18
DE3667292D1 (de) 1990-01-11
CA1278755C (en) 1991-01-08
FI861039A0 (fi) 1986-03-13

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