DK118611B - 3,4-cis-4-Aryl-isoflavaner og syreadditionssalte deraf til anvendelse i antifertilitetsmidler. - Google Patents

3,4-cis-4-Aryl-isoflavaner og syreadditionssalte deraf til anvendelse i antifertilitetsmidler.

Info

Publication number
DK118611B
DK118611B DK80167AA DK80167A DK118611B DK 118611 B DK118611 B DK 118611B DK 80167A A DK80167A A DK 80167AA DK 80167 A DK80167 A DK 80167A DK 118611 B DK118611 B DK 118611B
Authority
DK
Denmark
Prior art keywords
isoflavanes
cis
aryl
acid addition
addition salts
Prior art date
Application number
DK80167AA
Other languages
Danish (da)
English (en)
Inventor
E Ag Merck
Original Assignee
E Ag Merck
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E Ag Merck filed Critical E Ag Merck
Publication of DK118611B publication Critical patent/DK118611B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK80167AA 1966-02-16 1967-02-14 3,4-cis-4-Aryl-isoflavaner og syreadditionssalte deraf til anvendelse i antifertilitetsmidler. DK118611B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEM0068414 1966-02-16

Publications (1)

Publication Number Publication Date
DK118611B true DK118611B (da) 1970-09-14

Family

ID=7312594

Family Applications (1)

Application Number Title Priority Date Filing Date
DK80167AA DK118611B (da) 1966-02-16 1967-02-14 3,4-cis-4-Aryl-isoflavaner og syreadditionssalte deraf til anvendelse i antifertilitetsmidler.

Country Status (11)

Country Link
US (1) US3535344A (enExample)
BE (1) BE694025A (enExample)
CH (1) CH494222A (enExample)
DE (1) DE1543749A1 (enExample)
DK (1) DK118611B (enExample)
ES (1) ES336869A1 (enExample)
FR (1) FR6192M (enExample)
GB (1) GB1103094A (enExample)
IL (1) IL27321A (enExample)
NL (1) NL6702140A (enExample)
SE (1) SE328301B (enExample)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053626A (en) * 1973-03-13 1977-10-11 Merck Patent Gesellschaft Mit Beschrankter Haftung Cholesterol level-lowering phenoxyacetic acids
EP1477178A3 (en) * 1992-05-19 2005-02-16 KELLY, Graham Edmund Health supplements containing phyto-oestrogens, analogues or metabolites thereof
US5446061A (en) * 1993-11-05 1995-08-29 Eli Lilly And Company Methods for lowering serum cholesterol
US5407955A (en) * 1994-02-18 1995-04-18 Eli Lilly And Company Methods for lowering serum cholesterol and inhibiting smooth muscle cell proliferation, restenosis, endometriosis, and uterine fibroid disease
US5446071A (en) * 1994-11-18 1995-08-29 Eli Lilly And Company Methods for lowering serum cholesterol
HUP9800521A3 (en) * 1995-01-13 1999-12-28 Novo Nordisk As Use of 3,4-diphenyl chromans for the manufacture of a pharmaceutical composition for the treatment or propylaxis of hyperlipoproteinaemia, hypertriglyceridaemia, hyperlipidaemia or hypercholesterolaemia or arteriosclerosis
BE1010487A6 (nl) 1996-06-11 1998-10-06 Unilin Beheer Bv Vloerbekleding bestaande uit harde vloerpanelen en werkwijze voor het vervaardigen van dergelijke vloerpanelen.
AUPO203996A0 (en) * 1996-08-30 1996-09-26 Novogen Research Pty Ltd Therapeutic uses
US5985306A (en) * 1996-10-28 1999-11-16 Novo Nordisk A/S (+)-enantiomers of cis-3,4-chroman derivatives useful in prevention or treatment of estrogen diseases or syndromes
IL129616A0 (en) * 1996-10-28 2000-02-29 Novo Nordisk As Novel CIS-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
ZA979648B (en) * 1996-10-28 1998-04-28 Novo Nordisk As Heterocyclic compounds, compositions and uses.
AU4772297A (en) * 1996-10-28 1998-05-22 Novo Nordisk A/S Novel (cis)-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
CA2269936A1 (en) * 1996-10-28 1998-05-07 Lise Brown Christiansen Novel trans-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
AU4699997A (en) * 1996-10-28 1998-05-22 Novo Nordisk A/S Novel (cis)-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
US5958967A (en) * 1996-10-28 1999-09-28 Novo Nordisk A/S Cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
EP0937058A1 (en) * 1996-10-28 1999-08-25 Novo Nordisk A/S NOVEL $i(CIS)-3,4-CHROMAN DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES
ZA979644B (en) * 1996-10-28 1998-04-28 Novo Nordisk As Heterocyclic compounds, compositions and uses.
ZA979650B (en) * 1996-10-28 1998-04-28 Novo Nordisk As Heterocyclic compounds, compositions and uses.
WO1998018771A1 (en) * 1996-10-28 1998-05-07 Novo Nordisk A/S Novel (-)-enantiomers of cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
US5919817A (en) * 1996-10-28 1999-07-06 Novo Nordisk A/S Cis-3, 4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
US5994390A (en) * 1996-10-28 1999-11-30 Novo Nordisk Trans-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
US6043269A (en) * 1996-10-28 2000-03-28 Novo Nordisk A/S cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
US6316494B1 (en) 1996-10-28 2001-11-13 Novo Nordisk A/S cis3, 4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
US6146668A (en) 1997-04-28 2000-11-14 Novogen, Inc. Preparation of isoflavones from legumes
CA2287965C (en) * 1997-05-01 2009-10-20 Graham Edmund Kelly Treatment or prevention of menopausal symptoms and osteoporosis
AUPP112497A0 (en) * 1997-12-24 1998-01-22 Novogen Research Pty Ltd Compositions and method for protecting skin from UV induced immunosupression and skin damage
AUPP260798A0 (en) 1998-03-26 1998-04-23 Novogen Research Pty Ltd Treatment of medical related conditions with isoflavone containing extracts of clover
KR20000001793A (ko) * 1998-06-13 2000-01-15 이경하 신규한 벤조피란 또는 티오벤조피란 유도체
AUPP868599A0 (en) * 1999-02-15 1999-03-11 Novogen Research Pty Ltd Production of isoflavone derivatives
US20090233999A1 (en) * 1999-09-06 2009-09-17 Novogen Research Pty Ltd Compositions and therapeutic methods involving isoflavones and analogues thereof
AUPQ266199A0 (en) * 1999-09-06 1999-09-30 Novogen Research Pty Ltd Compositions and therapeutic methods involving isoflavones and analogues thereof
AUPQ520300A0 (en) * 2000-01-21 2000-02-17 Novogen Research Pty Ltd Food product and process
JP4896335B2 (ja) * 2000-03-01 2012-03-14 ナームローゼ・フエンノートチヤツプ・オルガノン エストロゲン化合物としてのクロマン誘導体
AUPR363301A0 (en) * 2001-03-08 2001-04-05 Novogen Research Pty Ltd Dimeric isoflavones
US20050119301A1 (en) * 2001-03-16 2005-06-02 Alan Husband Treatment of restenosis
CN1902213B (zh) * 2003-11-18 2010-06-23 诺沃根研究股份有限公司 异黄酮类前药、其组合物和涉及它们的治疗方法
AU2004290613B2 (en) * 2003-11-18 2010-03-25 Novogen Research Pty Ltd Isoflavonoid prodrugs, compositions thereof and therapeutic methods involving same
US8080675B2 (en) 2004-09-21 2011-12-20 Marshall Edwards, Inc. Chroman derivatives, medicaments and use in therapy
NZ553834A (en) * 2004-09-21 2010-03-26 Novogen Res Pty Ltd 7-hydroxy-3,4-diphenyl-chroman and chromene derivatives
ES2773732T3 (es) 2010-11-01 2020-07-14 Mei Pharma Inc Composiciones de isoflavonoides y procedimientos para el tratamiento del cáncer
HUE054998T2 (hu) 2015-02-02 2021-10-28 Mei Pharma Inc Kombinációs terápiák emlõrák kezelésében való alkalmazásra

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3340276A (en) * 1964-04-01 1967-09-05 Ciba Geigy Corp 3, 4-diphenyl-chromans
CH471113A (de) * 1965-01-29 1969-04-15 Merck Ag E Verfahren zur Herstellung von wasserlöslichen Flavanoidderivaten
US3436393A (en) * 1965-12-27 1969-04-01 Parke Davis & Co 4'-methoxy-2,2,4-trialkyl-delta**3-isoflavan compounds

Also Published As

Publication number Publication date
CH494222A (de) 1970-07-31
SE328301B (enExample) 1970-09-14
FR6192M (enExample) 1968-07-22
IL27321A (en) 1970-09-17
BE694025A (enExample) 1967-08-14
NL6702140A (enExample) 1967-08-17
GB1103094A (en) 1968-02-14
DE1543749A1 (de) 1969-12-11
ES336869A1 (es) 1968-05-01
US3535344A (en) 1970-10-20

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