DK1183035T3 - BONE MARROW TRANSPLANT TREATMENT stroke - Google Patents

BONE MARROW TRANSPLANT TREATMENT stroke Download PDF

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Publication number
DK1183035T3
DK1183035T3 DK00935910T DK00935910T DK1183035T3 DK 1183035 T3 DK1183035 T3 DK 1183035T3 DK 00935910 T DK00935910 T DK 00935910T DK 00935910 T DK00935910 T DK 00935910T DK 1183035 T3 DK1183035 T3 DK 1183035T3
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DK
Denmark
Prior art keywords
cells
bone marrow
mscs
transplantation
brain
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Application number
DK00935910T
Other languages
Danish (da)
English (en)
Inventor
Yi Li
Michael Chopp
Original Assignee
Ford Henry Health System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Ford Henry Health System filed Critical Ford Henry Health System
Application granted granted Critical
Publication of DK1183035T3 publication Critical patent/DK1183035T3/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
DK00935910T 1999-05-14 2000-05-11 BONE MARROW TRANSPLANT TREATMENT stroke DK1183035T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13434499P 1999-05-14 1999-05-14
PCT/US2000/012875 WO2000069448A1 (en) 1999-05-14 2000-05-11 Bone marrow transplantation for treatment of stroke

Publications (1)

Publication Number Publication Date
DK1183035T3 true DK1183035T3 (en) 2015-03-09

Family

ID=22462927

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00935910T DK1183035T3 (en) 1999-05-14 2000-05-11 BONE MARROW TRANSPLANT TREATMENT stroke

Country Status (9)

Country Link
US (1) US20090162327A1 (https=)
EP (1) EP1183035B1 (https=)
JP (1) JP2002544234A (https=)
AU (1) AU780994B2 (https=)
CA (1) CA2373808C (https=)
DK (1) DK1183035T3 (https=)
ES (1) ES2531592T3 (https=)
PT (1) PT1183035E (https=)
WO (1) WO2000069448A1 (https=)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6653134B2 (en) * 1995-03-28 2003-11-25 Cp Hahnemann University Isolated stromal cells for use in the treatment of diseases of the central nervous system
US20050169896A1 (en) * 1999-05-14 2005-08-04 Henry Ford Health System Bone marrow transplantation for treatment of stroke
US8017112B2 (en) 1999-05-14 2011-09-13 Henry Ford Health System Transplantation of bone marrow stromal cells for treatment of neurodegenerative diseases
IL148175A0 (en) * 1999-08-18 2002-09-12 Gen Hospital Corp Methods, compositions and kits for promoting recovery from damage to the central nervous system
US6749850B1 (en) 1999-08-18 2004-06-15 The General Hospital Corporation Methods, compositions and kits for promoting recovery from damage to the central nervous system
WO2001075094A1 (en) * 2000-04-04 2001-10-11 Thomas Jefferson University Application of myeloid-origin cells to the nervous system
EP1302534A4 (en) 2000-06-26 2004-06-16 Renomedix Inst Inc CELL FRACTION WITH CELLS WHICH ARE ABLE TO DIFFERENTIATE IN NERVOUS CELLS
ES2180433B1 (es) * 2001-05-28 2004-05-16 Universidad Miguel Hernandez De Elche. Empleo de celulas madre hematopoyeticas en la generacion de celulas madre neurales.
US9969980B2 (en) 2001-09-21 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
WO2003038075A1 (en) * 2001-10-30 2003-05-08 Renomedix Institute Inc. Method of inducing differentiation of mesodermal stem cells, es cells or immortalized cells into nervous system cells
EP1469852A4 (en) * 2002-01-04 2009-12-02 Ford Henry Health System NITROGEN DONORS FOR THE TREATMENT OF DISEASE AND INJURY
AU2003202988A1 (en) 2002-01-14 2003-07-30 The Board Of Trustees Of The University Of Illinois Use of modified pyrimidine compounds to promote stem cell migration and proliferation
US9969977B2 (en) 2002-09-20 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
WO2005007176A1 (ja) * 2003-06-27 2005-01-27 Renomedix Institute Inc. 間葉系細胞を有効成分とする体内投与用脳神経疾患治療薬
US20060210544A1 (en) 2003-06-27 2006-09-21 Renomedix Institute, Inc. Internally administered therapeutic agents for cranial nerve diseases comprising mesenchymal cells as an active ingredient
RU2283121C2 (ru) * 2004-11-29 2006-09-10 Государственное учреждение Научно-исследовательский институт клинической иммунологии СО РАМН Способ лечения инсульта
US20080107632A1 (en) * 2006-09-06 2008-05-08 Henrich Cheng Fibrin glue composition for repairing nerve damage and methods thereof
EP2171043B1 (en) 2007-06-15 2015-03-18 Garnet BioTherapeutics, Inc Treatment of diseases and disorders using self-renewing colony forming cells cultured and expanded in vitro
JP5276816B2 (ja) * 2007-09-10 2013-08-28 肇 井上 神経機能改善剤
WO2009108632A1 (en) * 2008-02-28 2009-09-03 Henry Ford Health System Compositions and methods for using stromal cells to enhance treatment of central nervous system injuries
EP2953473B1 (en) 2013-02-06 2018-11-28 Nc Medical Research Inc. Method of producing a heterogeneous subpopulation of bone marrow cells suitable for the treatement of neurodegeneration cased by ischemic stroke
CA2926575C (en) * 2013-10-14 2023-01-31 Hadasit Medical Research Services & Development Limited Method of obtaining terminally differentiated neuronal lineages and uses thereof
WO2015174087A1 (ja) * 2014-05-16 2015-11-19 公益財団法人先端医療振興財団 脳梗塞の予防及び/又は治療の為の医薬
RU2612981C1 (ru) * 2015-12-21 2017-03-14 Алексей Сергеевич Бывальцев Способ лечения ишемического инсульта
US11464804B1 (en) 2017-11-15 2022-10-11 Enrico Stazzone Intrathecal multifactorial infusion of heterogeneous autologous cell therapy

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4666828A (en) * 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4801531A (en) * 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
US5272057A (en) * 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5192659A (en) * 1989-08-25 1993-03-09 Genetype Ag Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
US5612211A (en) * 1990-06-08 1997-03-18 New York University Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors
US5851832A (en) * 1991-07-08 1998-12-22 Neurospheres, Ltd. In vitro growth and proliferation of multipotent neural stem cells and their progeny
US5750376A (en) * 1991-07-08 1998-05-12 Neurospheres Holdings Ltd. In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny
PT696205E (pt) * 1993-04-13 2002-07-31 Us Gov Health & Human Serv Utilizacao de linhas celulares fetais nauro-derivadas para terapia de transplantacao
US6653134B2 (en) * 1995-03-28 2003-11-25 Cp Hahnemann University Isolated stromal cells for use in the treatment of diseases of the central nervous system
AU3888699A (en) * 1998-05-07 1999-11-23 University Of South Florida Bone marrow cells as a source of neurons for brain and spinal cord repair
GB9904281D0 (en) * 1999-02-24 1999-04-21 Reneuron Ltd Transplantation

Also Published As

Publication number Publication date
EP1183035B1 (en) 2014-12-03
CA2373808C (en) 2011-04-19
AU780994B2 (en) 2005-04-28
WO2000069448A1 (en) 2000-11-23
EP1183035A1 (en) 2002-03-06
CA2373808A1 (en) 2000-11-23
AU5130000A (en) 2000-12-05
US20090162327A1 (en) 2009-06-25
JP2002544234A (ja) 2002-12-24
ES2531592T3 (es) 2015-03-17
PT1183035E (pt) 2015-03-04
EP1183035A4 (en) 2003-05-07

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