DK1179014T3 - Derivater af Z-domænet fra staphylococcalt protein A (SPA), som interagerer med mindst ét domæne fra human faktor VIII - Google Patents

Derivater af Z-domænet fra staphylococcalt protein A (SPA), som interagerer med mindst ét domæne fra human faktor VIII

Info

Publication number
DK1179014T3
DK1179014T3 DK00921293T DK00921293T DK1179014T3 DK 1179014 T3 DK1179014 T3 DK 1179014T3 DK 00921293 T DK00921293 T DK 00921293T DK 00921293 T DK00921293 T DK 00921293T DK 1179014 T3 DK1179014 T3 DK 1179014T3
Authority
DK
Denmark
Prior art keywords
domain
spa
derivatives
factor viii
human factor
Prior art date
Application number
DK00921293T
Other languages
English (en)
Inventor
Per-Ake Nygren
Mathias Uhlen
Charlotta Ljungqvist
Karin Nord
Original Assignee
Biovitrum Ab Publ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biovitrum Ab Publ filed Critical Biovitrum Ab Publ
Application granted granted Critical
Publication of DK1179014T3 publication Critical patent/DK1179014T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK00921293T 1999-04-19 2000-04-17 Derivater af Z-domænet fra staphylococcalt protein A (SPA), som interagerer med mindst ét domæne fra human faktor VIII DK1179014T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9901379A SE9901379D0 (sv) 1999-04-19 1999-04-19 Receptor structures
PCT/SE2000/000732 WO2000063243A1 (en) 1999-04-19 2000-04-17 Derivatives of the b or z domain from staphylococcal protein a (spa) interacting with at least one domain of human factor viii

Publications (1)

Publication Number Publication Date
DK1179014T3 true DK1179014T3 (da) 2009-04-06

Family

ID=20415254

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00921293T DK1179014T3 (da) 1999-04-19 2000-04-17 Derivater af Z-domænet fra staphylococcalt protein A (SPA), som interagerer med mindst ét domæne fra human faktor VIII

Country Status (8)

Country Link
EP (1) EP1179014B1 (da)
JP (1) JP4578690B2 (da)
AT (1) ATE417058T1 (da)
AU (1) AU4162400A (da)
DE (1) DE60041052D1 (da)
DK (1) DK1179014T3 (da)
SE (1) SE9901379D0 (da)
WO (1) WO2000063243A1 (da)

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JP2005504261A (ja) * 2001-01-12 2005-02-10 アフィボディ・アーベー 検出方法
JP4554356B2 (ja) * 2002-04-29 2010-09-29 アフィボディ・アーベー サンドイッチアッセイおよびキット
ATE328906T1 (de) * 2002-06-28 2006-06-15 Domantis Ltd Dual-specifische liganden mit erhöhter halbwertszeit
US9321832B2 (en) 2002-06-28 2016-04-26 Domantis Limited Ligand
TWI353991B (en) 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
SE0301936D0 (sv) * 2003-06-30 2003-06-30 Affibody Ab New polypeptide
JP4871126B2 (ja) * 2003-07-04 2012-02-08 アフィボディ・アーベー Ｈｅｒ２に対する結合親和性を有するポリペプチド
SE0301987D0 (sv) * 2003-07-04 2003-07-04 Affibody Ab New polypeptide
GB0524788D0 (en) 2005-12-05 2006-01-11 Affibody Ab Polypeptides
WO2008127457A2 (en) 2006-12-06 2008-10-23 Repligen Corporation Nucleic acids encoding recombinant protein a
US7989216B2 (en) 2006-12-08 2011-08-02 General Electric Company Two helix binders
US7977118B2 (en) 2006-12-08 2011-07-12 General Electric Company Two helix binders
US7981691B2 (en) 2006-12-08 2011-07-19 General Electric Company Two helix binders
US8198043B2 (en) 2006-12-08 2012-06-12 General Electric Company Two helix binders
NZ579594A (en) 2007-03-12 2012-03-30 Esbatech Alcon Biomed Res Unit Sequence based engineering and optimization of single chain antibodies
WO2009000099A2 (en) 2007-06-25 2008-12-31 Esbatech Ag Methods of modifying antibodies, and modified antibodies with improved functional properties
EP2164961B1 (en) 2007-06-25 2015-01-07 ESBATech, an Alcon Biomedical Research Unit LLC Sequence based engineering and optimization of single chain antibodies
WO2009019117A1 (en) * 2007-08-03 2009-02-12 Affibody Ab Igf-1r binding polypeptides and their use
GB2453589A (en) 2007-10-12 2009-04-15 King S College London Protease inhibition
DK3241843T3 (da) 2008-06-25 2021-09-06 Novartis Ag Opløselighedsoptimering af immunbindere
US8592555B2 (en) 2008-08-11 2013-11-26 Emd Millipore Corporation Immunoglobulin-binding proteins with improved specificity
MX2011001583A (es) 2008-08-11 2011-04-04 Nektar Therapeutics Conjugados de alcanoato polimericos de multiples brazos.
EP2323695B1 (en) 2008-08-19 2018-12-05 Nektar Therapeutics Complexes of small-interfering nucleic acids
SG162687A1 (en) 2008-12-24 2010-07-29 Millipore Corp Caustic stable chromatography ligands
JP5917417B2 (ja) 2010-03-05 2016-05-11 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 抗体の選択的強化
AU2011274423B2 (en) 2010-07-09 2016-02-11 Bioverativ Therapeutics Inc. Chimeric clotting factors
WO2012088422A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of taxane-based compounds
WO2012088445A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
US20140088021A1 (en) 2011-05-27 2014-03-27 Nektar Therapeutics Water-Soluble Polymer-Linked Binding Moiety and Drug Compounds
SG10201604554WA (en) 2011-06-08 2016-07-28 Emd Millipore Corp Chromatography matrices including novel staphylococcus aureus protein a based ligands
EP3939613A1 (en) 2011-08-11 2022-01-19 ONO Pharmaceutical Co., Ltd. Therapeutic agent for autoimmune diseases comprising pd-1 agonist
NZ626620A (en) 2012-01-10 2016-07-29 Biogen Ma Inc Enhancement of transport of therapeutic molecules across the blood brain barrier
WO2013175276A1 (en) 2012-05-23 2013-11-28 Argen-X B.V Il-6 binding molecules
EP3489396B1 (en) 2012-12-27 2021-03-03 National Institute of Advanced Industrial Science and Technology Molecule library constructed on the basis of backbone structure of microprotein
EP3019520B1 (en) * 2013-07-10 2019-12-11 GE Healthcare BioProcess R&D AB Mutated immunoglobulin-binding polypeptides
JP7138411B2 (ja) * 2013-08-28 2022-09-16 アフィボディ・アーベー 変異した骨格を有する結合ポリペプチド
WO2021006199A1 (ja) 2019-07-05 2021-01-14 小野薬品工業株式会社 Ｐｄ－１／ｃｄ３二重特異性タンパク質による血液がん治療
WO2021025140A1 (ja) 2019-08-08 2021-02-11 小野薬品工業株式会社 二重特異性タンパク質
US20230399375A1 (en) 2022-04-15 2023-12-14 Kyverna Therapeutics, Inc. Methods and compositions for treating autoimmune disease
WO2023212704A2 (en) * 2022-04-29 2023-11-02 Tezcat Biosciences, Inc. Macropinocytosis selective non-binding protein-drug conjugates
WO2023217904A1 (en) 2022-05-10 2023-11-16 Institut National de la Santé et de la Recherche Médicale Syncitin-1 fusion proteins and uses thereof for cargo delivery into target cells

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Publication number Priority date Publication date Assignee Title
FI86885C (fi) 1984-04-20 1992-10-26 Genentech Inc Foerfarande foer framstaellning av human rekombinantfaktor viii och nukleinsyrasekvenser och vektorer anvaend daertill
SE8501050D0 (sv) 1985-03-05 1985-03-05 Kabivitrum Ab Biologically active fragments of human antihemophilic factor and method for preparation thereof
SE465222C5 (sv) 1989-12-15 1998-02-10 Pharmacia & Upjohn Ab Ett rekombinant, humant faktor VIII-derivat och förfarande för dess framställning
SE468050C (sv) 1991-03-15 1998-04-27 Pharmacia & Upjohn Ab Rekombinant derivat av human faktor VIII
SE9400088D0 (sv) * 1994-01-14 1994-01-14 Kabi Pharmacia Ab Bacterial receptor structures

Also Published As

Publication number Publication date
JP4578690B2 (ja) 2010-11-10
AU4162400A (en) 2000-11-02
WO2000063243A1 (en) 2000-10-26
EP1179014A1 (en) 2002-02-13
ATE417058T1 (de) 2008-12-15
JP2002542259A (ja) 2002-12-10
EP1179014B1 (en) 2008-12-10
DE60041052D1 (de) 2009-01-22
SE9901379D0 (sv) 1999-04-19

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