DK1175420T3 - Fremgangsmåde til fremstilling af N6-substituerede deaza-adenosinderivater - Google Patents

Fremgangsmåde til fremstilling af N6-substituerede deaza-adenosinderivater

Info

Publication number
DK1175420T3
DK1175420T3 DK99966215T DK99966215T DK1175420T3 DK 1175420 T3 DK1175420 T3 DK 1175420T3 DK 99966215 T DK99966215 T DK 99966215T DK 99966215 T DK99966215 T DK 99966215T DK 1175420 T3 DK1175420 T3 DK 1175420T3
Authority
DK
Denmark
Prior art keywords
preparation
adenosine derivatives
deaza
substituted
substituted deaza
Prior art date
Application number
DK99966215T
Other languages
Danish (da)
English (en)
Inventor
Walter Rodriguez
James P Sherbine
Rick G Woodward
Adam W Sledeski
Matthew R Powers
Michael K O'brien
Diane C Salazar
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Application granted granted Critical
Publication of DK1175420T3 publication Critical patent/DK1175420T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK99966215T 1998-12-21 1999-12-14 Fremgangsmåde til fremstilling af N6-substituerede deaza-adenosinderivater DK1175420T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11307798P 1998-12-21 1998-12-21
PCT/US1999/029643 WO2000037469A2 (en) 1998-12-21 1999-12-14 Process for preparing n6-substituted deaza-adenosine derivatives

Publications (1)

Publication Number Publication Date
DK1175420T3 true DK1175420T3 (da) 2003-07-07

Family

ID=22347487

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99966215T DK1175420T3 (da) 1998-12-21 1999-12-14 Fremgangsmåde til fremstilling af N6-substituerede deaza-adenosinderivater

Country Status (28)

Country Link
US (1) US6184382B1 (de)
EP (1) EP1175420B1 (de)
JP (1) JP2002533343A (de)
KR (1) KR20010087425A (de)
CN (1) CN1122667C (de)
AP (1) AP1336A (de)
AT (1) ATE235493T1 (de)
AU (1) AU774155B2 (de)
BG (1) BG105624A (de)
BR (1) BR9917088A (de)
CA (1) CA2357760A1 (de)
CZ (1) CZ20012283A3 (de)
DE (1) DE69906392T2 (de)
DK (1) DK1175420T3 (de)
EA (1) EA003645B1 (de)
EE (1) EE200100333A (de)
ES (1) ES2191489T3 (de)
HK (1) HK1041607A1 (de)
HU (1) HUP0105224A3 (de)
ID (1) ID30118A (de)
IL (1) IL143843A0 (de)
NO (1) NO319789B1 (de)
NZ (1) NZ512500A (de)
PL (1) PL349154A1 (de)
PT (1) PT1175420E (de)
SK (1) SK284767B6 (de)
WO (1) WO2000037469A2 (de)
YU (1) YU51401A (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE301120T1 (de) * 1996-12-11 2005-08-15 Aventis Pharma Inc Herstellung von (1s-(1a,2b,3b,4(s*)))-4-(7-((1-(3-chlor-2-thien l)methyl)propyl)amino)-3h-imidazo(4,5-b)pyridin 3-yl)-n-ethyl-2,3- dihydroxycyclopentancarboxamid
KR100446669B1 (ko) * 2002-04-04 2004-09-04 (주) 비엔씨바이오팜 2-(헤테로사이클릭-알킬아미노)피리딘 유도체, 그제조방법 및 이를 포함하는 항바이러스용 약학적 조성물
US7291603B2 (en) * 2002-07-24 2007-11-06 Ptc Therapeutics, Inc. Nucleoside compounds and their use for treating cancer and diseases associated with somatic mutations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5652366A (en) * 1990-09-25 1997-07-29 Rhone-Poulenc Rorer Pharmaceuticals Inc. DI (1R)-(-)camphosulfonic acid) salt, preparation thereof and use thereof
AU654507B2 (en) * 1990-09-25 1994-11-10 Rhone-Poulenc Rorer International (Holdings) Inc. Compounds having antihypertensive and anti-ischemic properties
US5561134A (en) * 1990-09-25 1996-10-01 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties

Also Published As

Publication number Publication date
JP2002533343A (ja) 2002-10-08
ES2191489T3 (es) 2003-09-01
YU51401A (sh) 2003-12-31
AP2001002200A0 (en) 2001-09-30
HUP0105224A2 (en) 2002-06-29
AP1336A (en) 2004-11-30
NO319789B1 (no) 2005-09-12
PT1175420E (pt) 2003-08-29
BR9917088A (pt) 2006-01-31
BG105624A (en) 2002-01-31
EP1175420B1 (de) 2003-03-26
ATE235493T1 (de) 2003-04-15
CA2357760A1 (en) 2000-06-29
WO2000037469A2 (en) 2000-06-29
US6184382B1 (en) 2001-02-06
EP1175420A2 (de) 2002-01-30
NO20013044D0 (no) 2001-06-19
SK284767B6 (sk) 2005-11-03
NZ512500A (en) 2003-01-31
EA003645B1 (ru) 2003-08-28
HK1041607A1 (zh) 2002-07-12
EE200100333A (et) 2002-08-15
WO2000037469B1 (en) 2000-11-02
CZ20012283A3 (cs) 2001-10-17
NO20013044L (no) 2001-08-20
CN1333773A (zh) 2002-01-30
IL143843A0 (en) 2002-04-21
AU2181400A (en) 2000-07-12
CN1122667C (zh) 2003-10-01
KR20010087425A (ko) 2001-09-15
ID30118A (id) 2001-11-08
HUP0105224A3 (en) 2003-01-28
PL349154A1 (en) 2002-07-01
AU774155B2 (en) 2004-06-17
DE69906392T2 (de) 2004-02-05
WO2000037469A3 (en) 2000-09-14
EA200100697A1 (ru) 2001-12-24
DE69906392D1 (de) 2003-04-30
SK9072001A3 (en) 2001-12-03

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DK1175420T3 (da) Fremgangsmåde til fremstilling af N6-substituerede deaza-adenosinderivater
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