DK117225B - Fremgangsmåde til fremstilling af mono- eller di-N-bis-(β-klor- eller bromætyl)-karbamidsyreestere af østran-, androstan- eller pregnanforbindelser. - Google Patents

Fremgangsmåde til fremstilling af mono- eller di-N-bis-(β-klor- eller bromætyl)-karbamidsyreestere af østran-, androstan- eller pregnanforbindelser.

Info

Publication number
DK117225B
DK117225B DK173064AA DK173064A DK117225B DK 117225 B DK117225 B DK 117225B DK 173064A A DK173064A A DK 173064AA DK 173064 A DK173064 A DK 173064A DK 117225 B DK117225 B DK 117225B
Authority
DK
Denmark
Prior art keywords
estrane
androstane
bromoethyl
chloro
mono
Prior art date
Application number
DK173064AA
Other languages
Danish (da)
English (en)
Inventor
K Hoegberg
H Fex
I Koenyves
P Kneip
Original Assignee
Leo Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB14160/63A external-priority patent/GB1016959A/en
Application filed by Leo Ab filed Critical Leo Ab
Publication of DK117225B publication Critical patent/DK117225B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C19/00—Apparatus specially adapted for applying particulate materials to surfaces
    • B05C19/02—Apparatus specially adapted for applying particulate materials to surfaces using fluidised-bed techniques
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Paints Or Removers (AREA)
  • Glass Compositions (AREA)
DK173064AA 1963-04-09 1964-04-08 Fremgangsmåde til fremstilling af mono- eller di-N-bis-(β-klor- eller bromætyl)-karbamidsyreestere af østran-, androstan- eller pregnanforbindelser. DK117225B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB14160/63A GB1016959A (en) 1963-04-09 1963-04-09 Substituted steroid hormones

Publications (1)

Publication Number Publication Date
DK117225B true DK117225B (da) 1970-03-31

Family

ID=10036092

Family Applications (1)

Application Number Title Priority Date Filing Date
DK173064AA DK117225B (da) 1963-04-09 1964-04-08 Fremgangsmåde til fremstilling af mono- eller di-N-bis-(β-klor- eller bromætyl)-karbamidsyreestere af østran-, androstan- eller pregnanforbindelser.

Country Status (10)

Country Link
US (2) US3299104A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE646319A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR6458190D0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH452514A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK117225B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES298429A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI41742B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR3331M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO123943B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE314977B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3499158A (en) * 1964-04-24 1970-03-03 Raytheon Co Circuits utilizing the threshold properties of recombination radiation semiconductor devices
GB1523035A (en) 1976-03-10 1978-08-31 Leo Ab Derivatives of estradiol - 17 - dihydrogen phosphates
EP0105404A1 (en) * 1982-09-30 1984-04-18 Merck & Co. Inc. Derivatives of steroid compounds linked to cyotoxic agents and process for their preparation
SE8802402D0 (sv) * 1988-06-28 1988-06-28 Pharmacia Ab Novel esters
US5041434A (en) * 1991-08-17 1991-08-20 Virginia Lubkin Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application
JP2554005B2 (ja) * 1993-02-18 1996-11-13 株式会社パーマケム・アジア エストラムスチンフォスフェート又はその塩類の精製方法
US6500669B1 (en) * 1994-05-04 2002-12-31 Massachusetts Institute Of Technology Programmable genotoxic agents and uses therefor
US5882941A (en) * 1994-05-04 1999-03-16 Massachusette Institute Of Technology Programmable genotoxic agents and uses therefor
GB9419153D0 (en) * 1994-09-22 1994-11-09 Erba Carlo Spa Estramustine formulations with improved pharmaceutical properties
US20040072889A1 (en) * 1997-04-21 2004-04-15 Pharmacia Corporation Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
WO2014168986A1 (en) 2013-04-08 2014-10-16 Brown Dennis M Therapeutic benefit of suboptimally administered chemical compounds
WO2015117146A1 (en) 2014-02-03 2015-08-06 Quadriga Biosciences, Inc. Beta-substituted gamma-amino acids and analogs as chemotherapeutic agents
DK3102195T3 (da) 2014-02-03 2021-12-20 Quadriga Biosciences Inc Beta-substituerede beta-aminosyrer og analoger som kemoterapeutiske midler
CN108026026B (zh) 2015-08-03 2021-02-09 夸德里加生物科学公司 作为化疗剂的β-取代的β-氨基酸和类似物及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2885413A (en) * 1956-12-17 1959-05-05 Upjohn Co 11-oxygenated estradiol compounds and derivatives
US3081298A (en) * 1959-08-28 1963-03-12 Ciba Geigy Corp New cyclohemiacetals and cyclohemiacetal esters of the pregnane series and a processfor their manufacture

Also Published As

Publication number Publication date
ES298429A1 (es) 1964-10-16
US3299104A (en) 1967-01-17
USRE29199E (en) 1977-05-03
NO123943B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1972-02-07
BE646319A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1964-07-31
FR3331M (fr) 1965-05-24
SE314977B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1969-09-22
CH452514A (de) 1968-03-15
FI41742B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1969-10-31
BR6458190D0 (pt) 1973-12-26

Similar Documents

Publication Publication Date Title
DK117225B (da) Fremgangsmåde til fremstilling af mono- eller di-N-bis-(β-klor- eller bromætyl)-karbamidsyreestere af østran-, androstan- eller pregnanforbindelser.
DK105157C (da) Fremgangsmåde til fremstilling af Δ<1,4>-16-α-metylsteroider.
DK125086B (da) Fremgangsmåde til fremstilling af 11β,17α-dihydroxysteroider af pregnanrækken eller 17α-carboxylsyreestere deraf.
DK104346C (da) Fremgangsmåde til fremstilling af 6-metylen-3-oxo-Δ<4>-steroider.
DK120540B (da) Fremgangsmåde til fremstilling af 17α-alkynyl-17β-acyloxysteroider af androstan- eller estranrækken.
DK114060B (da) Fremgangsmåde til fremstilling af terapeutisk virksomme 1,2β-metylensteroider af androstan- eller 9-norandrostanrækken.
DK119156B (da) Fremgangsmåde til fremstilling af 6α-methyl-16-methylen-steroider af pregnanrækken.
DK103396C (da) Fremgangsmåde til fremstilling af estere af 17α-ethynyl-5(10)-estren-3β,17β-diol.
DK119657B (da) Fremgangsmåde til fremstilling af 17α-acyloxy-21-hydroxy-steroider af pregnanrækken.
DK112380B (da) Fremgangsmåde til fremstilling af 6-methyl-3-oxo-Δ<4,7>-steroider af pregnanrækken.
DK132226B (da) Fremgangsmåde til fremstilling af 16alfa, 17alfa-dialkylsteroider af pregnanrækken.
DK104674C (da) Fremgangsmåde til fremstilling af 19-nor-steroidforbindelser af androstan- eller pregnanrækken.
DK114686B (da) Fremgangsmåde til fremstilling af allencarboxylsyreestere.
DK111615B (da) Fremgangsmåde til fremstilling af 6α,9α-difluor-16α-metyl-Δ<1,4>-pregnadien-11β,21-diol-3,20-dion eller estere deraf.
DK104786C (da) Fremgangsmåde til fremstilling af 6-methyl-3-oxo-Δ<4,6>-steroider.
DK121297B (da) Fremgangsmåde til fremstilling af 19-hydroxyandrost-4-en-3,17-dion.
DK101117C (da) Fremgangsmåde til fremstilling af Δ<3,5>-steroider af pregnan-, androstan- eller østranrækken.
DK100167C (da) Fremgangsmåde til fremstilling af 16α,17α-dihydroxyforbindelser af pregnanrækken.
DK116732B (da) Fremgangsmåde til fremstilling af 19-nor-3-hydroxy-1,3,5,(10)-trien-steroider.
DK114898B (da) Fremgangsmåde til fremstilling af 20-halogen-3-keto-steroider af pregnanrækken eller 17-halogen-3-ketosteroider af androstanrækken.
DK112381B (da) Fremgangsmåde til fremstilling af 16-fluormethylen-17α-hydroxy-20-keto-steroider af pregnan-, 19-nor-pregnan- eller iso-pregnanrækken eller 17α-estere deraf.
DK102292C (da) Fremgangsmåde til fremstilling af 17α-hydroxy-20-keto-16β-methyl-steroider.
DK115179B (da) Fremgangsmåde til fremstilling af retrosteroider af androstanrækken.
DK100613C (da) Fremgangsmåde til fremstilling af 17α-halogenethinylsteroider af androstan- eller 19-nor-androstandrækken.
DK100294C (da) Fremgangsmåde til fremstilling af 4-hydroxy-3-keto-Δ<4>-steroider af androstan- eller 19-nor-androstanrækken.