DK115846B - Fremgangsmåde til fremstilling af (3,5-diamino-6-halogenpyrazinoyl)guanidin- eller (3,5-diamino-6-halogenpyrazinamido)guanidin-forbindelser eller syreadditionssalte deraf. - Google Patents
Fremgangsmåde til fremstilling af (3,5-diamino-6-halogenpyrazinoyl)guanidin- eller (3,5-diamino-6-halogenpyrazinamido)guanidin-forbindelser eller syreadditionssalte deraf.Info
- Publication number
- DK115846B DK115846B DK286567A DK286567A DK115846B DK 115846 B DK115846 B DK 115846B DK 286567 A DK286567 A DK 286567A DK 286567 A DK286567 A DK 286567A DK 115846 B DK115846 B DK 115846B
- Authority
- DK
- Denmark
- Prior art keywords
- diamino
- guanidine
- halopyrazinoyl
- halopyrazinamido
- preparation
- Prior art date
Links
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 title 2
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 title 1
- 150000002357 guanidines Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57491066A | 1966-08-25 | 1966-08-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK115846B true DK115846B (da) | 1969-11-17 |
Family
ID=24298148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK286567A DK115846B (da) | 1966-08-25 | 1967-06-01 | Fremgangsmåde til fremstilling af (3,5-diamino-6-halogenpyrazinoyl)guanidin- eller (3,5-diamino-6-halogenpyrazinamido)guanidin-forbindelser eller syreadditionssalte deraf. |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE699436A (enrdf_load_stackoverflow) |
| CH (1) | CH487167A (enrdf_load_stackoverflow) |
| DK (1) | DK115846B (enrdf_load_stackoverflow) |
| ES (1) | ES341322A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1158399A (enrdf_load_stackoverflow) |
| NL (1) | NL6707564A (enrdf_load_stackoverflow) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4224447A (en) * | 1979-03-27 | 1980-09-23 | Merck & Co., Inc. | Novel pyrazinecarboxamides and processes for preparing same |
| US4246406A (en) * | 1979-03-27 | 1981-01-20 | Merck & Co., Inc. | Heterocyclic substituted pyrazinoylguanidines |
| US6858615B2 (en) | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenyl guanidine sodium channel blockers |
| MX2010006421A (es) | 2007-12-10 | 2010-06-25 | Novartis Ag | Compuestos organicos. |
| AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
| RU2018138195A (ru) | 2012-12-17 | 2018-12-18 | Пэрион Сайенсиз, Инк. | Соединения 3,5-диамино-6-хлор-n-(n-(4- фенилбутил)карбамимидоил)пиразин-2-карбоксамида |
| JP6392242B2 (ja) | 2012-12-17 | 2018-09-19 | パリオン・サイエンシィズ・インコーポレーテッド | 粘膜への水分付与が不十分であることが好都合である疾患の治療に有用なクロロ−ピラジンカルボキサミド誘導体 |
| US9102633B2 (en) | 2013-12-13 | 2015-08-11 | Parion Sciences, Inc. | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds |
-
1967
- 1967-05-31 NL NL6707564A patent/NL6707564A/xx unknown
- 1967-06-01 DK DK286567A patent/DK115846B/da unknown
- 1967-06-02 BE BE699436D patent/BE699436A/xx unknown
- 1967-06-02 ES ES341322A patent/ES341322A1/es not_active Expired
- 1967-06-07 CH CH803567A patent/CH487167A/de not_active IP Right Cessation
- 1967-06-07 GB GB2621167A patent/GB1158399A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES341322A1 (es) | 1968-10-01 |
| BE699436A (enrdf_load_stackoverflow) | 1967-12-04 |
| GB1158399A (en) | 1969-07-16 |
| NL6707564A (enrdf_load_stackoverflow) | 1968-02-26 |
| CH487167A (de) | 1970-03-15 |
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