ES341322A1 - Un procedimiento para la preparacion de pirazinoilguanidi- nas y pirazinamidoguanidinas. - Google Patents
Un procedimiento para la preparacion de pirazinoilguanidi- nas y pirazinamidoguanidinas.Info
- Publication number
- ES341322A1 ES341322A1 ES341322A ES341322A ES341322A1 ES 341322 A1 ES341322 A1 ES 341322A1 ES 341322 A ES341322 A ES 341322A ES 341322 A ES341322 A ES 341322A ES 341322 A1 ES341322 A1 ES 341322A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- hydrogen
- phenyl
- pyrazinamido
- pyrazinoyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- USVSPZQIBAJOIQ-UHFFFAOYSA-N n-(diaminomethylideneamino)pyrazine-2-carboxamide Chemical class NC(=N)NNC(=O)C1=CN=CC=N1 USVSPZQIBAJOIQ-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 13
- 239000001257 hydrogen Substances 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 4
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000004122 cyclic group Chemical group 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000005036 alkoxyphenyl group Chemical group 0.000 abstract 1
- 125000005037 alkyl phenyl group Chemical group 0.000 abstract 1
- HAMNKKUPIHEESI-UHFFFAOYSA-N aminoguanidine Chemical compound NNC(N)=N HAMNKKUPIHEESI-UHFFFAOYSA-N 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Chemical group 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000005059 halophenyl group Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57491066A | 1966-08-25 | 1966-08-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES341322A1 true ES341322A1 (es) | 1968-10-01 |
Family
ID=24298148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES341322A Expired ES341322A1 (es) | 1966-08-25 | 1967-06-02 | Un procedimiento para la preparacion de pirazinoilguanidi- nas y pirazinamidoguanidinas. |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE699436A (enrdf_load_stackoverflow) |
| CH (1) | CH487167A (enrdf_load_stackoverflow) |
| DK (1) | DK115846B (enrdf_load_stackoverflow) |
| ES (1) | ES341322A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1158399A (enrdf_load_stackoverflow) |
| NL (1) | NL6707564A (enrdf_load_stackoverflow) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4224447A (en) * | 1979-03-27 | 1980-09-23 | Merck & Co., Inc. | Novel pyrazinecarboxamides and processes for preparing same |
| US4246406A (en) * | 1979-03-27 | 1981-01-20 | Merck & Co., Inc. | Heterocyclic substituted pyrazinoylguanidines |
| US6858615B2 (en) | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenyl guanidine sodium channel blockers |
| MX2010006421A (es) | 2007-12-10 | 2010-06-25 | Novartis Ag | Compuestos organicos. |
| AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
| RU2018138195A (ru) | 2012-12-17 | 2018-12-18 | Пэрион Сайенсиз, Инк. | Соединения 3,5-диамино-6-хлор-n-(n-(4- фенилбутил)карбамимидоил)пиразин-2-карбоксамида |
| JP6392242B2 (ja) | 2012-12-17 | 2018-09-19 | パリオン・サイエンシィズ・インコーポレーテッド | 粘膜への水分付与が不十分であることが好都合である疾患の治療に有用なクロロ−ピラジンカルボキサミド誘導体 |
| US9102633B2 (en) | 2013-12-13 | 2015-08-11 | Parion Sciences, Inc. | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds |
-
1967
- 1967-05-31 NL NL6707564A patent/NL6707564A/xx unknown
- 1967-06-01 DK DK286567A patent/DK115846B/da unknown
- 1967-06-02 BE BE699436D patent/BE699436A/xx unknown
- 1967-06-02 ES ES341322A patent/ES341322A1/es not_active Expired
- 1967-06-07 CH CH803567A patent/CH487167A/de not_active IP Right Cessation
- 1967-06-07 GB GB2621167A patent/GB1158399A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK115846B (da) | 1969-11-17 |
| BE699436A (enrdf_load_stackoverflow) | 1967-12-04 |
| GB1158399A (en) | 1969-07-16 |
| NL6707564A (enrdf_load_stackoverflow) | 1968-02-26 |
| CH487167A (de) | 1970-03-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES431056A1 (es) | Procedimiento para la preparacion de nuevos n- (metoximetil-furilmetil)-6, 7-benzomorfanos y -morfinanos. | |
| ES431775A1 (es) | Procedimiento para la preparacion de derivados de 1-fenil-2-aminoguanidina. | |
| ES341322A1 (es) | Un procedimiento para la preparacion de pirazinoilguanidi- nas y pirazinamidoguanidinas. | |
| ES439927A1 (es) | Procedimiento para la obtencion de 7-metoxi-6-tiatetracicli-nas. | |
| IE41503L (en) | Pipeazinyl-benzimidazoles | |
| GB937723A (en) | Pyrazolo-pyrimidines and process for their manufacture | |
| ES422906A1 (es) | Un procedimiento para preparar nuevos derivados de 2-amino-indano. | |
| ES433816A1 (es) | Procedimiento para preparar derivados de amidoxina. | |
| ES425374A1 (es) | Procedimiento para la produccion de pirazolonas-(5). | |
| ES341324A1 (es) | Un procedimiento para la preparacion de pirazinoilguanidi- nas y pirazinamidoguanidinas. | |
| ES341321A1 (es) | Un procedimiento para la preparacion de pirazinoilguanidi- nas y pirazinamidoguanidinas. | |
| GB984022A (en) | D-homoandrost-9(11)-ene-18-nitrile derivatives and their preparation | |
| ES422922A1 (es) | Procedimiento de preparacion de nuevos derivados dienicos de la serie del androstano. | |
| GB1272337A (en) | New basic carbamates and preparation thereof | |
| GB1110792A (en) | Novel 5(10)-dehydro-steroids | |
| ES301365A1 (es) | Un método para la preparación de un compuesto diurético | |
| ES325827A1 (es) | Procedimiento para producir compuestos de 2-fenoxi-2-fenilacetamida. | |
| ES401174A1 (es) | Procedimiento para la preparacion de nuevos esteres alcohi-licos del acido tiolcarbamidico basicamente sustituidos. | |
| GB1042205A (en) | Manufacture of benzo[a]quinolizines | |
| ES437041A1 (es) | Un procedimiento para preparar derivados de 1-ftalazona. | |
| GB910262A (en) | New nicotinic acid esters and methods of producing them | |
| ES397454A1 (es) | Un procedimiento para la preparacion de derivados de tetra-hidro-isoquinolina. | |
| ES415477A1 (es) | Un procedimiento para preparar benzocicloheptaisoquinolei- nas. | |
| GB1416248A (en) | Anthraquinone derivatives | |
| ES390087A1 (es) | Procedimiento para la obtencion de nuevos 3-guanidinoalquil-tiofenos. |