DK1157004T3 - Sammensætning omfattende MX-DTPA og dets anvendelse til fremstilling af et radiomærket MX-DTPA - Google Patents

Sammensætning omfattende MX-DTPA og dets anvendelse til fremstilling af et radiomærket MX-DTPA

Info

Publication number
DK1157004T3
DK1157004T3 DK00913703T DK00913703T DK1157004T3 DK 1157004 T3 DK1157004 T3 DK 1157004T3 DK 00913703 T DK00913703 T DK 00913703T DK 00913703 T DK00913703 T DK 00913703T DK 1157004 T3 DK1157004 T3 DK 1157004T3
Authority
DK
Denmark
Prior art keywords
dtpa
radiolabelled
manufacture
composition
provides
Prior art date
Application number
DK00913703T
Other languages
English (en)
Inventor
Paul Chinn
Albert Gyorkos
Michael J Labarre
Steve Ruhl
Thomas Ryskamp
Original Assignee
Biogen Idec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Idec Inc filed Critical Biogen Idec Inc
Application granted granted Critical
Publication of DK1157004T3 publication Critical patent/DK1157004T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00—Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/16—Isothiocyanates
    • C07C331/28—Isothiocyanates having isothiocyanate groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Catalysts (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Detergent Compositions (AREA)
  • Cosmetics (AREA)
DK00913703T 1999-03-03 2000-03-02 Sammensætning omfattende MX-DTPA og dets anvendelse til fremstilling af et radiomærket MX-DTPA DK1157004T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/261,207 US6207858B1 (en) 1999-03-03 1999-03-03 Regioselective synthesis of DTPA derivatives
PCT/US2000/005433 WO2000051976A1 (en) 1999-03-03 2000-03-02 Regioselective synthesis of dtpa derivatives

Publications (1)

Publication Number Publication Date
DK1157004T3 true DK1157004T3 (da) 2008-09-15

Family

ID=22992340

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00913703T DK1157004T3 (da) 1999-03-03 2000-03-02 Sammensætning omfattende MX-DTPA og dets anvendelse til fremstilling af et radiomærket MX-DTPA

Country Status (20)

Country Link
US (1) US6207858B1 (da)
EP (1) EP1157004B1 (da)
JP (2) JP5357368B2 (da)
CN (2) CN1290830C (da)
AT (1) ATE396175T1 (da)
AU (1) AU778816B2 (da)
BR (1) BR0008693A (da)
CA (1) CA2364960C (da)
CY (1) CY1108271T1 (da)
DE (1) DE60038953D1 (da)
DK (1) DK1157004T3 (da)
ES (1) ES2304944T3 (da)
HK (1) HK1069380A1 (da)
MX (1) MXPA01008784A (da)
NO (1) NO328049B1 (da)
PL (1) PL211510B1 (da)
PT (1) PT1157004E (da)
RU (1) RU2312852C2 (da)
WO (1) WO2000051976A1 (da)
ZA (1) ZA200106750B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207858B1 (en) * 1999-03-03 2001-03-27 Idec Pharmaceuticals Corporation Regioselective synthesis of DTPA derivatives
TWI284539B (en) * 2001-07-30 2007-08-01 Epix Pharm Inc A method for making a magnetic resonance (MR) imaging agent, a MR imaging contrast agent, a method for altering stability of a peptide and a modified peptide
US7563433B2 (en) * 2007-01-11 2009-07-21 Immunomedics, Inc. Methods and compositions for F-18 labeling of proteins, peptides and other molecules
US7597876B2 (en) * 2007-01-11 2009-10-06 Immunomedics, Inc. Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules
US7993626B2 (en) 2007-01-11 2011-08-09 Immunomedics, Inc. Methods and compositions for F-18 labeling of proteins, peptides and other molecules
US20040208828A1 (en) * 2003-02-04 2004-10-21 Lutz Lehmann Enantiomer-pure (4S,8S)- and (4R,8R)-4-p-nitrobenzyl-8-methyl-3,6,9-triaza-3N,6N,9N-tricarboxymethyl-1,11-undecanedioic acid and derivatives thereof, process for their production and use for the production of pharmaceutical agents
DE10305463A1 (de) * 2003-02-04 2004-08-12 Schering Ag Enantiomerenreines (4S,8S)- und (4R,8R)-4-p-Nitrobenzyl-8-methyl-3,6,9-triza-3N,6N,9N-tricarboxymethyl-1,11-undecandisäure und deren Abkömmlinge, Verfahren zu deren Herstellung und Verwendung zur Herstellung pharmazeutischer Mittel
DE10305462A1 (de) * 2003-02-04 2004-08-12 Schering Ag Konjugate enantiomerenreiner (4S,8S)- und (4R,8R)-4-p-Benzyl-8-methyl-3,6,9-triaza-3N, 6N, 9N-tricarboxymethyl-1,11-undecandisäure mit Biomolekülen, Verfahren zu deren Herstellung und Verwendung zur Herstellung
JP2008501638A (ja) * 2004-04-23 2008-01-24 ドイツ連邦共和国 ＩＣＯＳ陽性細胞のｉｎｖｉｖｏ枯渇によるＴ細胞介在病態の治療方法
JP2009508090A (ja) * 2005-08-31 2009-02-26 イムノメディクス， インコーポレイテッド 予め標的化されたポジトロン放出断層撮影画像化のためのｆ−１８ペプチド
US8288530B2 (en) 2006-11-06 2012-10-16 The United States Of America, As Represented By The Department Of Health And Human Services Method of preparing macromolecular contrast agents and uses thereof
US8545809B2 (en) 2007-01-11 2013-10-01 Immunomedics, Inc. Methods and compositions for improved 18F labeling of proteins, peptides and other molecules
US8153100B2 (en) * 2007-01-11 2012-04-10 Immunomedics, Inc. Methods and compositions for F-18 labeling of proteins, peptides and other molecules
US8202509B2 (en) * 2007-01-11 2012-06-19 Immunomedics, Inc. Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules
US8398956B2 (en) 2007-01-11 2013-03-19 Immunomedics, Inc. In vivo copper-free click chemistry for delivery of therapeutic and/or diagnostic agents
US8889100B2 (en) 2007-01-11 2014-11-18 Immunomedics, Inc. Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules
US8709382B2 (en) 2007-01-11 2014-04-29 Immunomedics, Inc. Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules
WO2010011367A2 (en) * 2008-02-22 2010-01-28 Illinois Institute Of Technology Bimodal ligands with macrocyclic and acyclic binding moieties, complexes and compositions thereof, and methods of using
US9446995B2 (en) 2012-05-21 2016-09-20 Illinois Institute Of Technology Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions
US10189803B2 (en) 2008-02-22 2019-01-29 Illinois Institute Of Technology Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions
US10556873B2 (en) 2008-02-22 2020-02-11 Illinois Institute Of Technology Bimodal ligands with macrocyclic and acyclic binding moieties, complexes and compositions thereof, and methods of using
CN102773078A (zh) * 2012-07-16 2012-11-14 武汉纺织大学 同时吸附阳、阴离子的固体配位萃取剂及其制备和应用
US10441669B2 (en) 2013-10-04 2019-10-15 Illinois Institute Of Technology Multifunctional chelators, complexes, and compositions thereof, and methods of using same
CN103601648B (zh) * 2013-11-19 2015-03-25 宜兴市丰泽化工有限公司 一种dtpa五钠盐的脱盐提纯方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5246692A (en) * 1986-09-05 1993-09-21 The United States Of America As Represented By The Secretary Of Health And Human Services Backbone polysubstituted chelates for forming a metal chelate-protein conjugate
US5099069A (en) * 1986-09-05 1992-03-24 Gansow Otto A Backbone polysubstituted chelates for forming a metal chelate-protein conjugate
EP0529645B1 (en) * 1986-09-05 1996-10-23 GANSOW, Otto A. Process for the preparation of backbone polysubstituted chelates
US4831175A (en) * 1986-09-05 1989-05-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Backbone polysubstituted chelates for forming a metal chelate-protein conjugate
AU638757B2 (en) * 1989-05-26 1993-07-08 Akzo N.V. Chelating agents for attaching metal ions to proteins
US5124471A (en) * 1990-03-26 1992-06-23 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Bifunctional dtpa-type ligand
CA2149329C (en) * 1992-11-13 2008-07-15 Darrell R. Anderson Therapeutic application of chimeric and radiolabeled antibodies to human b lymphocyte restricted differentiation antigen for treatment of b cell lymphoma
CA2180662A1 (en) * 1994-01-07 1995-07-13 Ramaswamy Subramanian New polyaminocarboxylate chelators
US20020102208A1 (en) * 1999-03-01 2002-08-01 Paul Chinn Radiolabeling kit and binding assay
US6207858B1 (en) * 1999-03-03 2001-03-27 Idec Pharmaceuticals Corporation Regioselective synthesis of DTPA derivatives

Also Published As

Publication number Publication date
WO2000051976A1 (en) 2000-09-08
NO20014194D0 (no) 2001-08-29
CA2364960A1 (en) 2000-09-08
NO20014194L (no) 2001-10-26
PL211510B1 (pl) 2012-05-31
PL350903A1 (en) 2003-02-10
JP5357368B2 (ja) 2013-12-04
US6207858B1 (en) 2001-03-27
EP1157004A1 (en) 2001-11-28
CN1290830C (zh) 2006-12-20
HK1069380A1 (en) 2005-05-20
AU3509900A (en) 2000-09-21
CN1342141A (zh) 2002-03-27
BR0008693A (pt) 2001-12-26
MXPA01008784A (es) 2002-04-24
AU778816B2 (en) 2004-12-23
RU2312852C2 (ru) 2007-12-20
ZA200106750B (en) 2002-11-15
CN1548419A (zh) 2004-11-24
NO328049B1 (no) 2009-11-16
ES2304944T3 (es) 2008-11-01
JP2002538137A (ja) 2002-11-12
JP2013144705A (ja) 2013-07-25
CA2364960C (en) 2010-05-11
PT1157004E (pt) 2008-08-29
CY1108271T1 (el) 2014-02-12
EP1157004B1 (en) 2008-05-21
ATE396175T1 (de) 2008-06-15
DE60038953D1 (de) 2008-07-03

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