DK115376A - Kinolonderivater - Google Patents
KinolonderivaterInfo
- Publication number
- DK115376A DK115376A DK115376A DK115376A DK115376A DK 115376 A DK115376 A DK 115376A DK 115376 A DK115376 A DK 115376A DK 115376 A DK115376 A DK 115376A DK 115376 A DK115376 A DK 115376A
- Authority
- DK
- Denmark
- Prior art keywords
- kinolon
- derivatives
- kinolon derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB11644/75A GB1502312A (en) | 1975-03-20 | 1975-03-20 | Quinolone derivatives |
| GB4204375 | 1975-10-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK115376A true DK115376A (da) | 1976-09-21 |
Family
ID=26248416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK115376A DK115376A (da) | 1975-03-20 | 1976-03-17 | Kinolonderivater |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4066651A (mo) |
| JP (1) | JPS51118773A (mo) |
| AU (1) | AU1147676A (mo) |
| CS (1) | CS188273B2 (mo) |
| DD (1) | DD124117A5 (mo) |
| DE (1) | DE2611824A1 (mo) |
| DK (1) | DK115376A (mo) |
| ES (1) | ES446234A1 (mo) |
| FI (1) | FI760729A7 (mo) |
| FR (1) | FR2304342A1 (mo) |
| HU (1) | HU172032B (mo) |
| IE (1) | IE43079B1 (mo) |
| IL (1) | IL49126A0 (mo) |
| LU (1) | LU74594A1 (mo) |
| NL (1) | NL7602834A (mo) |
| NO (1) | NO760993L (mo) |
| PT (1) | PT64921B (mo) |
| SE (1) | SE434394B (mo) |
| SU (1) | SU648090A3 (mo) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE47592B1 (en) * | 1977-12-29 | 1984-05-02 | Ici Ltd | Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture |
| DK0382185T3 (da) * | 1989-02-10 | 1994-07-04 | Otsuka Pharma Co Ltd | Carbostyrilderivater |
| US5225402A (en) * | 1989-02-10 | 1993-07-06 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| EP0549729B1 (en) * | 1990-09-07 | 1997-12-17 | Schering Corporation | Antiviral compounds and antihypertensive compounds |
| TW198715B (mo) * | 1991-04-19 | 1993-01-21 | Dtsuka Seiyaku Kk | |
| EP0543018B1 (en) * | 1991-06-07 | 1996-01-10 | Otsuka Pharmaceutical Co., Ltd. | Antidiabetic agent |
| DE19839499A1 (de) * | 1998-08-29 | 2000-03-02 | Merck Patent Gmbh | 2-Oxo-2H-chinolinderivate |
| CN1391576A (zh) * | 1999-08-27 | 2003-01-15 | 利甘德药品公司 | 雄激素受体调节剂化合物及方法 |
| JP2003508397A (ja) | 1999-08-27 | 2003-03-04 | リガンド・ファーマシューティカルズ・インコーポレイテッド | アンドロゲンレセプターモジュレーターとしての８−置換−６−トリフルオロメチル−９−ピリド［３，２−ｇ］キノリン化合物 |
| US6566372B1 (en) * | 1999-08-27 | 2003-05-20 | Ligand Pharmaceuticals Incorporated | Bicyclic androgen and progesterone receptor modulator compounds and methods |
| PE20010647A1 (es) | 1999-09-14 | 2001-06-23 | Lilly Co Eli | Moduladores de receptores de retinoide x (rxr) con perfil farmacologico mejorado |
| FR2811912B1 (fr) * | 2000-07-21 | 2003-02-07 | Gattefosse Ets Sa | Procede d'enrobage de particules solides par un agent thermofusible, et particules solides ainsi enrobees |
| AU2004266160A1 (en) * | 2003-08-22 | 2005-03-03 | Ligand Pharmaceuticals Incorporated | 6-cycloamino-2-quinolinone derivatives as androgen receptor modulator compounds |
| GB0420722D0 (en) * | 2004-09-17 | 2004-10-20 | Addex Pharmaceuticals Sa | Novel allosteric modulators |
| AR059898A1 (es) | 2006-03-15 | 2008-05-07 | Janssen Pharmaceutica Nv | Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2 |
| TW200845978A (en) * | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
| TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
| WO2009033703A1 (en) * | 2007-09-14 | 2009-03-19 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | 1,3-disubstituted-4-phenyl-1 h-pyridin-2-ones |
| BRPI0816767B8 (pt) | 2007-09-14 | 2021-05-25 | Addex Pharmaceuticals Sa | composto 4-fenil-3,4,5,6-tetra-hidro-2h,1'h-[1,4']bipiridi¬nil-2'-onas 1',3'-dissubstituídas, composição farmacêutica e uso dos mesmos |
| ES2365966T3 (es) | 2007-09-14 | 2011-10-14 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | 4-(aril-x-fenil)-1h-piridin-2-onas 1,3-disustituidas. |
| ES2637794T3 (es) * | 2007-11-14 | 2017-10-17 | Janssen Pharmaceuticals, Inc. | Derivados de imidazo[1,2-A]piridina y su uso como moduladores alostéricos positivos de receptores MGLUR2 |
| WO2009062309A1 (en) * | 2007-11-15 | 2009-05-22 | Universite Laval | Methods for the regulation of the prostaglandin f synthase (pgfs) activity of akr1b1 and uses thereof |
| JP5547194B2 (ja) | 2008-09-02 | 2014-07-09 | ジャンセン ファーマシューティカルズ， インコーポレイテッド． | 代謝型グルタミン酸受容体の調節因子としての３−アザビシクロ［３．１．０］ヘキシル誘導体 |
| BRPI0920354A2 (pt) | 2008-10-16 | 2017-06-27 | Addex Pharmaceuticals Sa | derivados de indol e benzomorfolina como moduladores de receptores de glutamato metabotrópicos |
| CN102232074B (zh) | 2008-11-28 | 2014-12-03 | 奥梅-杨森制药有限公司 | 作为代谢性谷氨酸盐受体调节剂的吲哚和苯并噁嗪衍生物 |
| SG176021A1 (en) | 2009-05-12 | 2011-12-29 | Janssen Pharmaceuticals Inc | 1,2,4-triazolo [4,3-a] pyridine derivatives and their use for the treatment or prevention of neurological and psychiatric disorders |
| MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| BRPI1010831A2 (pt) | 2009-05-12 | 2016-04-05 | Addex Pharmaceuticals Sa | derivados de 1,2,4-triazolo[4,3-a]piridina e seu como moduladores alostéricos positivos de receptores de mglur2 |
| CN103261195B (zh) | 2010-11-08 | 2015-09-02 | 杨森制药公司 | 1,2,4-三唑并[4,3-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途 |
| AU2011328203B2 (en) | 2010-11-08 | 2015-03-19 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
| PT2649069E (pt) | 2010-11-08 | 2015-11-20 | Janssen Pharmaceuticals Inc | Derivados de 1,2,4-triazolo[4,3-a]piridina e sua utilização como moduladores alostéricos positivos de recetores mglur2 |
| JO3368B1 (ar) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
| JO3367B1 (ar) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2 |
| HUE045610T2 (hu) | 2014-01-21 | 2020-01-28 | Janssen Pharmaceutica Nv | 2-es altípusú metabotróp glutamáterg receptor pozitív allosztérikus modulátorait vagy ortosztérikus agonistáit tartalmazó kombinációk és alkalmazásuk |
| PH12021552653A1 (en) | 2014-01-21 | 2023-07-17 | Janssen Pharmaceutica Nv | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3772301A (en) * | 1971-11-22 | 1973-11-13 | Warner Lambert Co | (4-substituted)4-(methylsulfinyl)methylcarbostyrils |
-
1976
- 1976-02-23 IE IE352/76A patent/IE43079B1/en unknown
- 1976-02-25 SE SE7602339A patent/SE434394B/xx not_active IP Right Cessation
- 1976-02-27 AU AU11476/76A patent/AU1147676A/en not_active Expired
- 1976-03-01 US US05/662,685 patent/US4066651A/en not_active Expired - Lifetime
- 1976-03-01 IL IL49126A patent/IL49126A0/xx unknown
- 1976-03-17 DK DK115376A patent/DK115376A/da unknown
- 1976-03-18 DD DD191915A patent/DD124117A5/xx unknown
- 1976-03-18 FI FI760729A patent/FI760729A7/fi not_active Application Discontinuation
- 1976-03-18 LU LU74594A patent/LU74594A1/xx unknown
- 1976-03-18 NL NL7602834A patent/NL7602834A/xx not_active Application Discontinuation
- 1976-03-19 DE DE19762611824 patent/DE2611824A1/de active Granted
- 1976-03-19 SU SU762337250A patent/SU648090A3/ru active
- 1976-03-19 HU HU76IE00000737A patent/HU172032B/hu unknown
- 1976-03-19 FR FR7608061A patent/FR2304342A1/fr active Granted
- 1976-03-19 PT PT64921A patent/PT64921B/pt unknown
- 1976-03-19 NO NO760993A patent/NO760993L/no unknown
- 1976-03-19 CS CS761804A patent/CS188273B2/cs unknown
- 1976-03-20 ES ES446234A patent/ES446234A1/es not_active Expired
- 1976-03-22 JP JP51031184A patent/JPS51118773A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| SU648090A3 (ru) | 1979-02-15 |
| NO760993L (mo) | 1976-09-21 |
| IL49126A0 (en) | 1976-05-31 |
| CS188273B2 (en) | 1979-02-28 |
| DE2611824C2 (mo) | 1987-06-19 |
| FR2304342B1 (mo) | 1979-09-21 |
| IE43079B1 (en) | 1980-12-17 |
| FR2304342A1 (fr) | 1976-10-15 |
| DE2611824A1 (de) | 1976-09-30 |
| FI760729A7 (mo) | 1976-09-21 |
| US4066651A (en) | 1978-01-03 |
| IE43079L (en) | 1976-09-20 |
| SE7602339L (sv) | 1976-09-21 |
| PT64921A (en) | 1976-04-01 |
| HU172032B (hu) | 1978-05-28 |
| NL7602834A (nl) | 1976-09-22 |
| ES446234A1 (es) | 1977-10-01 |
| PT64921B (en) | 1977-08-24 |
| SE434394B (sv) | 1984-07-23 |
| JPH0122267B2 (mo) | 1989-04-25 |
| DD124117A5 (mo) | 1977-02-02 |
| LU74594A1 (mo) | 1977-05-06 |
| JPS51118773A (en) | 1976-10-18 |
| AU1147676A (en) | 1977-09-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK115376A (da) | Kinolonderivater | |
| BE844737A (fr) | Derives benzylideniques | |
| SE7601274L (sv) | Isoxazolylbensamid-derivat | |
| SE7611261L (sv) | Blockerade kolekalciferolderivat | |
| HU171396B (hu) | Sposob poluchenija proizvodnykh rifamicina | |
| ATA273676A (de) | Ablenkjoch | |
| ATA302176A (de) | Mikroskopokular | |
| ATA444276A (de) | Skiroller | |
| ATA59376A (de) | Schmiegeegge | |
| SE7613797L (sv) | Cyproheptadinderivat | |
| DK100076A (da) | Thioamider | |
| SE7601209L (sv) | Triazolobenzocykloalkyltiadiazinderivat | |
| ATA567176A (de) | Mikroskopokular | |
| ATA423676A (de) | Siliermittel | |
| ATA305976A (de) | Skistock | |
| SE7608519L (sv) | Morfantridin-derivat | |
| ATA155876A (de) | Rostmatte | |
| JPS51104845A (ja) | Ekishoserunoseizoho | |
| DD122967A1 (de) | Hylamin-derivate | |
| SE7613998L (sv) | Azetidinonderivat | |
| SE7602068L (sv) | Kvartera xantinylakylnortropinderivat | |
| DK187076A (da) | Benzobicyklononenderivater | |
| DK41976A (da) | Cyclohexadienderivater | |
| SE7605619L (sv) | 3-nitropyrazol-derivat | |
| SE7601208L (sv) | Triazolocykloalkylhydrotiadiazin-derivat |