DK112387D0 - Rensning af alfa-1-antiprotease - Google Patents

Rensning af alfa-1-antiprotease

Info

Publication number
DK112387D0
DK112387D0 DK112387A DK112387A DK112387D0 DK 112387 D0 DK112387 D0 DK 112387D0 DK 112387 A DK112387 A DK 112387A DK 112387 A DK112387 A DK 112387A DK 112387 D0 DK112387 D0 DK 112387D0
Authority
DK
Denmark
Prior art keywords
antiprotease
alfa
purification
Prior art date
Application number
DK112387A
Other languages
English (en)
Other versions
DK112387A (da
Inventor
Alex Joseph Bollen
Paul Chuchana
Marc Hoylaerts
Original Assignee
Smith Kline Rit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline Rit filed Critical Smith Kline Rit
Publication of DK112387D0 publication Critical patent/DK112387D0/da
Publication of DK112387A publication Critical patent/DK112387A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8125—Alpha-1-antitrypsin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/815—Enzyme separation or purification by sorption

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
DK112387A 1986-03-07 1987-03-04 Rensning af alfa-1-antiprotease DK112387A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/836,868 US4629567A (en) 1986-03-07 1986-03-07 Alpha-1-antiprotease purification

Publications (2)

Publication Number Publication Date
DK112387D0 true DK112387D0 (da) 1987-03-04
DK112387A DK112387A (da) 1987-09-08

Family

ID=25272922

Family Applications (1)

Application Number Title Priority Date Filing Date
DK112387A DK112387A (da) 1986-03-07 1987-03-04 Rensning af alfa-1-antiprotease

Country Status (7)

Country Link
US (1) US4629567A (da)
EP (1) EP0237515A3 (da)
JP (1) JPS62223197A (da)
AU (1) AU589337B2 (da)
DK (1) DK112387A (da)
PT (1) PT84415B (da)
ZA (1) ZA871634B (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4697003A (en) * 1985-11-01 1987-09-29 Miles Laboratories, Inc. Method of preparing alpha-1-proteinase inhibitor
IL80477A0 (en) * 1985-11-08 1987-02-27 Smithkline Beckman Corp Mutant coding sequence
US5059329A (en) * 1989-09-19 1991-10-22 Thymax Corporation Method for isolating dithiochrome, an insulin-binding molecule with glucose metabolism-related pharmaceutical utility
JP2832848B2 (ja) * 1989-10-21 1998-12-09 株式会社林原生物化学研究所 結晶２―Ｏ―α―Ｄ―グルコピラノシル―Ｌ―アスコルビン酸とその製造方法並びに用途
FR2711371B1 (fr) * 1993-10-18 1995-12-29 Aetsrn Procédé de préparation d'un concentré d'inter-alpha-trypsine inhibiteur à usage thérapeutique et concentré obtenu.
US6284874B1 (en) * 1994-06-17 2001-09-04 Alpha Therapeutic Corporation Process for separating α1-proteinase inhibitor from cohn fraction IV1 and IV4 paste
US5610285A (en) 1994-08-24 1997-03-11 Bayer Corporation Purification of α-1 proteinase inhibitor using novel chromatographic separation conditions
AU6884396A (en) 1995-09-07 1997-03-27 Ppl Therapeutics (Scotland) Ltd Purification of alpha-1 proteinase inhibitor
US5616693A (en) * 1996-07-01 1997-04-01 Alpha Therapeutic Corporation Process for seperating alpha-1-proteinase inhibitor from COHN IV1 +1V4 paste
US6849605B1 (en) * 1999-03-05 2005-02-01 The Trustees Of University Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of viral infections
US6489308B1 (en) 1999-03-05 2002-12-03 Trustees Of University Of Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of nitric-oxide-induced clinical conditions
WO2000051625A1 (en) * 1999-03-05 2000-09-08 The Trustees Of University Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of herpes viruses
WO2000051624A2 (en) * 1999-03-05 2000-09-08 The Trustees Of University Technology Corporation Methods and compositions useful in inhibiting apoptosis
US6462180B1 (en) 1999-11-24 2002-10-08 Bayer Corporation Method of preparing α-1 proteinase inhibitor
PT1343809E (pt) 2000-12-14 2015-09-22 Grifols Therapeutics Inc Método de preparação de inibidor de proteinase alfa-1
US7777006B2 (en) 2002-12-31 2010-08-17 Csl Behring L.L.C. Method for purification of alpha-1-antitrypsin
AU2015200572B2 (en) * 2002-12-31 2016-06-02 Csl Behring L.L.C. Method for purification of alpha-1-antitrypsin
US20050042772A1 (en) * 2003-02-07 2005-02-24 Beyond Genomics Removal of proteins from a sample
US20040220242A1 (en) * 2003-05-02 2004-11-04 Leland Shapiro Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide induced clinical conditions
EP1654284B1 (en) * 2003-08-12 2009-04-15 Octapharma AG Process for preparing an alpha-1-antitrypsin solution
CA2536918A1 (en) 2003-08-26 2005-03-03 Leland Shapiro Compositions of, and methods for, alpha-1 antitrypsin fc fusion molecules
WO2005027821A2 (en) * 2003-09-22 2005-03-31 Kamada Ltd. Large scale preparation of alpha-1 proteinase inhibitor and use thereof
US7807435B2 (en) * 2005-08-11 2010-10-05 Baxter International Inc. Method for the purification of alpha-1 proteinase inhibitor (a1PI)
GB0524432D0 (en) * 2005-11-30 2006-01-11 Nhs Blood & Transplant Method
US20080124303A1 (en) * 2005-12-12 2008-05-29 Cavit Sciences, Inc Methods and compositions for treatment of viral infections
ES2395667T3 (es) * 2006-03-30 2013-02-14 Baxter International Inc. Proceso para la purificación de alfa-1-antitripsina recombinante que implica un paso de cromatografía de intercambio aniónico
CN103408658A (zh) 2007-08-17 2013-11-27 Csl百灵有限公司 α-1-抗胰蛋白酶和载脂蛋白A-I的纯化方法
US9938353B2 (en) 2011-06-24 2018-04-10 The Regents Of The University Of Colorado, A Body Corporate Compositions, methods and uses for alpha-1 antitrypsin fusion molecules
EP2802653A4 (en) 2012-01-10 2015-09-02 Univ Colorado Regents ALPHA-1 ANTITRYPSIN FUSION MOLECULE COMPOSITIONS, METHODS AND USES THEREOF
WO2014160768A1 (en) 2013-03-29 2014-10-02 The Regents Of The University Of Colorado Compositions and methods for preparing a subject for organ or non-organ implantation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3808124A (en) * 1972-04-14 1974-04-30 American Cyanamid Co Purification of human plasminogen
US4264449A (en) * 1977-09-21 1981-04-28 American National Red Cross Antibody-specific solid phase immunoadsorbent, preparation thereof, and antibody purification therewith
US4205130A (en) * 1979-03-12 1980-05-27 Pirkko Vihko Method of purification of human prostatic acid phosphatase
SE8302483L (sv) * 1983-05-02 1984-11-03 Pharmacia Ind Forfarande vid rening av biologiskt aktiva substanser
US4525465A (en) * 1983-10-07 1985-06-25 Nippon Kayaku Kabushiki Kaisha Water-insoluble biospecific absorbent containing argininal derivative
US4697003A (en) * 1985-11-01 1987-09-29 Miles Laboratories, Inc. Method of preparing alpha-1-proteinase inhibitor
US4656254A (en) * 1985-12-02 1987-04-07 Miles Laboratories, Inc. Method of preparing alpha-1-proteinase inhibitor and antithrombin III

Also Published As

Publication number Publication date
ZA871634B (en) 1988-01-27
AU589337B2 (en) 1989-10-05
DK112387A (da) 1987-09-08
EP0237515A3 (fr) 1989-03-01
PT84415B (pt) 1989-10-04
AU6974187A (en) 1987-09-10
EP0237515A2 (fr) 1987-09-16
JPS62223197A (ja) 1987-10-01
US4629567A (en) 1986-12-16
PT84415A (en) 1987-04-01

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment