DK1108060T3 - Molekylære forskelle mellem arter af M. tuberculosis-komplekset - Google Patents

Molekylære forskelle mellem arter af M. tuberculosis-komplekset

Info

Publication number
DK1108060T3
DK1108060T3 DK99939702.9T DK99939702T DK1108060T3 DK 1108060 T3 DK1108060 T3 DK 1108060T3 DK 99939702 T DK99939702 T DK 99939702T DK 1108060 T3 DK1108060 T3 DK 1108060T3
Authority
DK
Denmark
Prior art keywords
deletions
bcg
isolates
tuberculosis
species
Prior art date
Application number
DK99939702.9T
Other languages
English (en)
Inventor
Michael A Wilson
Marcel Behr
Peter Small
Gary Schoolnik
Original Assignee
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leland Stanford Junior filed Critical Univ Leland Stanford Junior
Application granted granted Critical
Publication of DK1108060T3 publication Critical patent/DK1108060T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Door And Window Frames Mounted To Openings (AREA)
  • Special Wing (AREA)
  • Multicomponent Fibers (AREA)
  • Data Exchanges In Wide-Area Networks (AREA)
  • Load-Bearing And Curtain Walls (AREA)
DK99939702.9T 1998-08-25 1999-08-10 Molekylære forskelle mellem arter af M. tuberculosis-komplekset DK1108060T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9793698P 1998-08-25 1998-08-25
US09/318,191 US6291190B1 (en) 1998-08-25 1999-05-25 Molecular differences between species of the M. tuberculosis complex
PCT/US1999/017939 WO2000011214A1 (en) 1998-08-25 1999-08-10 Molecular differences between species of the m. tuberculosis complex

Publications (1)

Publication Number Publication Date
DK1108060T3 true DK1108060T3 (da) 2010-08-16

Family

ID=26793800

Family Applications (3)

Application Number Title Priority Date Filing Date
DK08015511.2T DK2006395T3 (da) 1998-08-25 1999-08-10 M. tuberculosis åben læseramme RV2660c og anvendelser deraf
DK08017907.0T DK2031075T3 (da) 1998-08-25 1999-08-10 M.tb åben læseramme Rv2659c og anvendelser deraf
DK99939702.9T DK1108060T3 (da) 1998-08-25 1999-08-10 Molekylære forskelle mellem arter af M. tuberculosis-komplekset

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK08015511.2T DK2006395T3 (da) 1998-08-25 1999-08-10 M. tuberculosis åben læseramme RV2660c og anvendelser deraf
DK08017907.0T DK2031075T3 (da) 1998-08-25 1999-08-10 M.tb åben læseramme Rv2659c og anvendelser deraf

Country Status (9)

Country Link
US (6) US6291190B1 (da)
EP (3) EP1108060B1 (da)
AT (3) ATE507308T1 (da)
AU (1) AU5394699A (da)
DE (3) DE69942569D1 (da)
DK (3) DK2006395T3 (da)
ES (1) ES2343927T3 (da)
PT (2) PT1108060E (da)
WO (1) WO2000011214A1 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040018574A1 (en) * 1998-08-25 2004-01-29 Marcel Behr Molecular differences between species of the M. tuberculosis complex
US6291190B1 (en) 1998-08-25 2001-09-18 The Board Of Trustees Of The Leland Stanford Junior University Molecular differences between species of the M. tuberculosis complex
FR2791067B1 (fr) * 1999-03-16 2003-01-31 Pasteur Institut Sequence deletees chez m.bovis bcg/m.ou m.tuberculosis, procede de detection des mycobacteries utilisant ces sequences et vaccins
EP1214088B1 (en) 1999-05-04 2009-04-22 The University of Medicine and Dentistry of New Jersey Proteins expressed by mycobacterium tuberculosis and not by bcg and their use as diagnostic reagents and vaccines
AU2002308128A1 (en) * 2001-04-10 2002-10-28 Nmi Naturwissenschaftliches Und Medizinisches Institut An Der Universitat Tubingen In Reutlingen Sti Method for determining analyte molecules in a sample
US7758874B2 (en) * 2002-02-19 2010-07-20 Albert Einstein College Of Medicine Of Yeshiva University Attenuated Mycobacterium tuberculosis vaccines
WO2003070164A2 (en) * 2002-02-19 2003-08-28 Albert Einstein College Of Medicine Of Yeshiva University Attenuated mycobacterium tuberculosis vaccines
EP1338657B9 (en) * 2002-02-25 2007-10-10 Institut Pasteur Sequences specifcally deleted from Mycobacterium tuberculosis genome and their use in diagnosistics and as vaccines
US7611720B2 (en) 2002-04-16 2009-11-03 Jun Liu Tuberculosis vaccines including recombinant BCG strains expressing alanine dehydrogenase, serine dehydratase and/or glutamine synthetase
WO2003093307A2 (en) * 2002-04-27 2003-11-13 The Secretary Of State For Environment, Food And Rural Affairs Mycobacterial antigens and uses thereof
WO2004097048A1 (en) * 2003-04-28 2004-11-11 Canon Kabushiki Kaisha Process for assay of nucleic acid by competitive hybridization using a dna microarray
ITRM20030411A1 (it) * 2003-08-29 2005-02-28 Consiglio Nazionale Ricerche Uso di sequenze geniche specifiche di mycobacterium tubercolosis ecorrispondenti proteine per la diagnosi e la prevenzione di infezione tubercolare.
US7608277B2 (en) * 2004-12-01 2009-10-27 Gene Therapy Systems, Inc. Tuberculosis nucleic acids, polypeptides and immunogenic compositions
EP1904848A2 (en) * 2005-04-29 2008-04-02 Fusion Antibodies Limited Assays for diagnosis of tuberculosis and uses thereof
WO2007014304A2 (en) 2005-07-26 2007-02-01 University Of Medicine And Dentistry Of New Jersey Antibody profiles characteristic of tuberculosis state
PT1922415E (pt) * 2005-09-05 2014-02-25 Bio Rad Innovations Uso de rd9 e is6110 como ácidos nucleicos-alvo para o diagnóstico da tuberculose, e fornecimento de alvos is6110 e rd9 compatíveis com uma utilização multiplex
US20090148870A1 (en) * 2006-05-18 2009-06-11 Ericson Daniel G Rapid Detection of Mycobacterium Tuberculosis and Antimicrobial Drug Resistance
BRPI0604958B1 (pt) * 2006-11-23 2022-05-17 Fundação Oswaldo Cruz Kit para distinção de mycobacterium tuberculosis, m. bovis, m. bovis bcg em uma amostra, e, método para distinguir mycobacterium tuberculosis, m. bovis, m. bovis bcg
CN101661044B (zh) * 2008-08-27 2013-10-16 复旦大学附属华山医院 一种结核病诊断试剂及试剂盒
CN102149822A (zh) * 2008-09-12 2011-08-10 株式会社Lg生命科学 用于检测结核分枝杆菌复合群或分枝杆菌属的组合物和使用所述组合物通过多重实时pcr来同时检测结核分枝杆菌复合群和分枝杆菌属的方法
GB0903168D0 (en) 2009-02-25 2009-04-08 Fusion Antibodies Ltd Diagnostic method and kit
US8961989B2 (en) 2009-11-20 2015-02-24 Oregon Health & Science University Methods for producing an immune response to tuberculosis
KR101158647B1 (ko) * 2010-05-27 2012-06-26 울산대학교 산학협력단 이중 실시간 중합효소연쇄반응법과 융해곡선분석을 이용하는 결핵균과 항산성비결핵균의 검출 방법
US9663758B2 (en) * 2013-03-12 2017-05-30 Wisconsin Alumni Research Foundation Global gene regulators (GGR) as vaccine candidates against paratuberculosis
WO2018068064A2 (en) * 2016-09-22 2018-04-12 Nguyen Hiep Hoa T Mycobacterium tuberculosis proteins in diagnostic assays and devices for tuberculosis detection and diagnosis
KR102247643B1 (ko) * 2019-11-01 2021-05-03 바이오파크진단 주식회사 결핵균 및 비결핵항산균을 검출하기 위한 2단계 진단방법 및 키트

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0681026A1 (en) * 1987-03-02 1995-11-08 Whitehead Institute For Biomedical Research Recombinant mycobacterial vaccine
US5591632A (en) 1987-03-02 1997-01-07 Beth Israel Hospital Recombinant BCG
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
PH27357A (en) * 1989-09-22 1993-06-21 Fujisawa Pharmaceutical Co Pyrazole derivatives and pharmaceutical compositions comprising the same
EP0499003A1 (en) * 1991-02-14 1992-08-19 N.V. Innogenetics S.A. Polypeptides and peptides, particularly recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnosis of tuberculosis
DK79793D0 (da) * 1993-07-02 1993-07-02 Statens Seruminstitut Diagnostic test
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US5700683A (en) 1995-02-17 1997-12-23 Pathogenesis Corporation Virulence-attenuating genetic deletions deleted from mycobacterium BCG
AU4996796A (en) 1995-02-28 1996-09-18 Joel R.L. Ehrenkranz Rapid, self-performing tsh immunoassay
US5686597A (en) 1995-06-06 1997-11-11 Incyte Pharmaceuticals, Inc. Thrombin receptor homolog
CA2276491C (en) * 1996-12-31 2008-01-22 New York University Early detection of mycobacterial disease
US20040013685A1 (en) * 1997-11-10 2004-01-22 Peter Andersen Nucleic acid fragments and polypeptide fragments derived from M. tuberculosis
US6291190B1 (en) * 1998-08-25 2001-09-18 The Board Of Trustees Of The Leland Stanford Junior University Molecular differences between species of the M. tuberculosis complex
EP1200466A2 (en) * 1999-07-13 2002-05-02 Statens Serum Institut Tuberculosis vaccine and diagnostics based on the mycobacterium tuberculosisesat-6 gene family

Also Published As

Publication number Publication date
US20080254052A1 (en) 2008-10-16
ES2343927T3 (es) 2010-08-12
DE69942569D1 (de) 2010-08-19
WO2000011214A1 (en) 2000-03-02
DK2006395T3 (da) 2011-07-18
EP2006395A1 (en) 2008-12-24
ATE466100T1 (de) 2010-05-15
EP2031075A1 (en) 2009-03-04
PT2006395E (pt) 2011-07-13
US6686166B2 (en) 2004-02-03
US20110206715A1 (en) 2011-08-25
ATE507308T1 (de) 2011-05-15
US20060002953A1 (en) 2006-01-05
EP1108060A1 (en) 2001-06-20
EP2031075B1 (en) 2010-07-07
EP1108060B1 (en) 2010-04-28
US6291190B1 (en) 2001-09-18
EP2006395B1 (en) 2011-04-27
DK2031075T3 (da) 2010-10-18
US20020176873A1 (en) 2002-11-28
AU5394699A (en) 2000-03-14
US7364740B2 (en) 2008-04-29
DE69942310D1 (de) 2010-06-10
US20040063923A1 (en) 2004-04-01
ATE473299T1 (de) 2010-07-15
WO2000011214B1 (en) 2000-04-13
US7700118B2 (en) 2010-04-20
PT1108060E (pt) 2010-08-04
DE69943401D1 (de) 2011-06-09

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