DK1104297T3 - Sammensætninger til behandling af kronisk lymfocytisk leukæmi - Google Patents

Sammensætninger til behandling af kronisk lymfocytisk leukæmi

Info

Publication number
DK1104297T3
DK1104297T3 DK99937222T DK99937222T DK1104297T3 DK 1104297 T3 DK1104297 T3 DK 1104297T3 DK 99937222 T DK99937222 T DK 99937222T DK 99937222 T DK99937222 T DK 99937222T DK 1104297 T3 DK1104297 T3 DK 1104297T3
Authority
DK
Denmark
Prior art keywords
lymphocytic leukemia
chronic lymphocytic
compositions
treatment
compounds
Prior art date
Application number
DK99937222T
Other languages
Danish (da)
English (en)
Inventor
Francis A Nardella
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc filed Critical Cephalon Inc
Application granted granted Critical
Publication of DK1104297T3 publication Critical patent/DK1104297T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
DK99937222T 1998-07-09 1999-07-08 Sammensætninger til behandling af kronisk lymfocytisk leukæmi DK1104297T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9246698P 1998-07-09 1998-07-09
US9487898P 1998-07-29 1998-07-29

Publications (1)

Publication Number Publication Date
DK1104297T3 true DK1104297T3 (da) 2006-05-29

Family

ID=26785713

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99937222T DK1104297T3 (da) 1998-07-09 1999-07-08 Sammensætninger til behandling af kronisk lymfocytisk leukæmi

Country Status (12)

Country Link
US (3) US6573292B1 (fr)
EP (1) EP1104297B8 (fr)
JP (1) JP2002520282A (fr)
AT (1) ATE315392T1 (fr)
AU (1) AU767586B2 (fr)
CA (1) CA2336932A1 (fr)
DE (1) DE69929440T2 (fr)
DK (1) DK1104297T3 (fr)
ES (1) ES2255287T3 (fr)
NZ (1) NZ509376A (fr)
PT (1) PT1104297E (fr)
WO (1) WO2000002555A1 (fr)

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CA2336932A1 (fr) * 1998-07-09 2000-01-20 Francis A. Nardella Procedes et compositions pour le traitement de la leucemie lymphocitaire chronique
US7105560B1 (en) 1999-07-23 2006-09-12 The Regents Of The University Of California Use of etodolac in the treatment of multiple myeloma
US7129262B2 (en) 1999-07-23 2006-10-31 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US7361680B2 (en) 1999-07-23 2008-04-22 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US6545034B1 (en) 1999-07-23 2003-04-08 The Regents Of The University Of California Use of etodolac for the treatment of chronic lymphocytic leukemia
US7151100B1 (en) 1999-07-23 2006-12-19 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US7211599B2 (en) 2002-09-19 2007-05-01 The Regents Of The University Of California Use of etodolac to treat hyperplasia
WO2005033113A2 (fr) * 2003-10-02 2005-04-14 Cephalon, Inc Derives indoles
US7638331B2 (en) 2004-01-02 2009-12-29 The Administration of the Tulane Rducation Fund Directed apoptosis in COX-2 overexpressing cancer cells through expression targeted gene delivery
AU2005317047A1 (en) * 2004-11-05 2006-06-22 Cephalon, Inc. Cancer treatments
US8436190B2 (en) 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
RU2474612C2 (ru) * 2008-05-20 2013-02-10 Инкурон ЛЛК Индуцирование гибели клеток путем ингибирования адаптивного теплового шокового ответа
CN102164579B (zh) * 2008-09-25 2014-10-15 赛福伦公司 苯达莫司汀的液体配制品
US8076366B2 (en) * 2009-01-15 2011-12-13 Cephalon, Inc. Forms of bendamustine free base
JP2013537552A (ja) 2010-08-18 2013-10-03 デル マー ファーマスーティカルズ ジアンヒドロガラクチトール及びジアセチルジアンヒドロガラクチトール等の置換ヘキシトールを含む準最適に投与された化合物の治療的有効性を改良するための組成物及び方法
AU2012389562A1 (en) 2011-08-17 2014-07-24 Dennis Brown Compositions and methods to improve the therapeutic benefit of subotimally administered chemical compounds including substituted hexitols such as dibromodulcitol
AU2013209394A1 (en) 2012-01-20 2014-08-28 Dennis Brown Use of substituted hexitols including dianhydrogalactitol and analogs to treat neoplastic disease and cancer stem cells including glioblastoma multforme and medulloblastoma
WO2013142817A2 (fr) 2012-03-23 2013-09-26 Dennis Brown Compositions et procédés d'amélioration du bénéfice thérapeutique de l'indirubine et de ses analogues y compris du mésoindigo
WO2013169600A1 (fr) 2012-05-09 2013-11-14 Delmar Pharmaceuticals Utilisation vétérinaire du dianhydrogalactitol, du diacétyldianhydrogalactitol, et du dibromodulcitol pour traiter des malignités
EP2872161B1 (fr) 2012-06-26 2020-12-16 Del Mar Pharmaceuticals Dianhydrogalactitol pour utilisation dans le traitement de malignités résistantes à un inhibiteur de tyrosine kinase chez des patients ayant des polymorphismes génétiques ou des dérégulations ou des mutations d'ahi1
KR102359214B1 (ko) 2014-04-04 2022-02-07 델 마 파마슈티컬스 폐의 비소세포 암종 및 난소암을 치료하기 위한 디안하이드로갈락티톨 및 이의 유사체 또는 유도체
US10434086B2 (en) 2014-04-06 2019-10-08 Incuron, Inc. Combination therapies with curaxins

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US7105560B1 (en) 1999-07-23 2006-09-12 The Regents Of The University Of California Use of etodolac in the treatment of multiple myeloma
US6545034B1 (en) * 1999-07-23 2003-04-08 The Regents Of The University Of California Use of etodolac for the treatment of chronic lymphocytic leukemia
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Also Published As

Publication number Publication date
ES2255287T3 (es) 2006-06-16
AU767586B2 (en) 2003-11-20
AU5209899A (en) 2000-02-01
EP1104297A1 (fr) 2001-06-06
US20050261356A1 (en) 2005-11-24
ATE315392T1 (de) 2006-02-15
NZ509376A (en) 2003-10-31
CA2336932A1 (fr) 2000-01-20
EP1104297A4 (fr) 2003-01-02
WO2000002555A1 (fr) 2000-01-20
US20030232874A1 (en) 2003-12-18
US6573292B1 (en) 2003-06-03
DE69929440D1 (de) 2006-04-06
US6921772B2 (en) 2005-07-26
PT1104297E (pt) 2006-05-31
EP1104297B8 (fr) 2006-05-03
JP2002520282A (ja) 2002-07-09
EP1104297B1 (fr) 2006-01-11
DE69929440T2 (de) 2006-08-17

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