DK1046395T3 - Plaster indeholdende heparin og diclofenac til topisk anvendelse - Google Patents
Plaster indeholdende heparin og diclofenac til topisk anvendelseInfo
- Publication number
- DK1046395T3 DK1046395T3 DK00107835T DK00107835T DK1046395T3 DK 1046395 T3 DK1046395 T3 DK 1046395T3 DK 00107835 T DK00107835 T DK 00107835T DK 00107835 T DK00107835 T DK 00107835T DK 1046395 T3 DK1046395 T3 DK 1046395T3
- Authority
- DK
- Denmark
- Prior art keywords
- topical use
- diclofenac
- containing heparin
- patches containing
- heparin
- Prior art date
Links
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 title abstract 2
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 title abstract 2
- 229920000669 heparin Polymers 0.000 title abstract 2
- 229960002897 heparin Drugs 0.000 title abstract 2
- 230000000699 topical effect Effects 0.000 title abstract 2
- 229960001259 diclofenac Drugs 0.000 title 1
- 206010018852 Haematoma Diseases 0.000 abstract 2
- 229920001499 Heparinoid Polymers 0.000 abstract 1
- 239000012790 adhesive layer Substances 0.000 abstract 1
- 230000036592 analgesia Effects 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000002554 heparinoid Substances 0.000 abstract 1
- 239000000017 hydrogel Substances 0.000 abstract 1
- 239000010410 layer Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/402—Anaestetics, analgesics, e.g. lidocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
- A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Materials Engineering (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1999MI000834A IT1312088B1 (it) | 1999-04-21 | 1999-04-21 | Cerotto per uso topico contenente eparina e diclofenac. |
EP00107835A EP1046395B1 (en) | 1999-04-21 | 2000-04-12 | Plaster for topical use containing heparin and diclofenac |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1046395T3 true DK1046395T3 (da) | 2005-10-03 |
Family
ID=11382783
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00107835T DK1046395T3 (da) | 1999-04-21 | 2000-04-12 | Plaster indeholdende heparin og diclofenac til topisk anvendelse |
Country Status (9)
Country | Link |
---|---|
US (3) | US6592891B1 (da) |
EP (1) | EP1046395B1 (da) |
AT (1) | ATE297717T1 (da) |
CA (1) | CA2306214C (da) |
DE (1) | DE60020768T2 (da) |
DK (1) | DK1046395T3 (da) |
ES (1) | ES2244373T3 (da) |
IT (1) | IT1312088B1 (da) |
PT (1) | PT1046395E (da) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE310539T1 (de) | 2001-12-21 | 2005-12-15 | Coloplast As | Artikel zur wundbehandlung |
WO2004039358A1 (en) * | 2002-10-30 | 2004-05-13 | Showa Denko K.K. | Adhesive composition for dermal patch and production process thereof |
JP2004168764A (ja) * | 2002-10-30 | 2004-06-17 | Showa Denko Kk | 貼付剤用粘着剤組成物およびその製造方法 |
EP1691746B1 (en) * | 2003-12-08 | 2015-05-27 | Gel-Del Technologies, Inc. | Mucoadhesive drug delivery devices and methods of making and using thereof |
EP1785131A4 (en) * | 2004-08-31 | 2009-03-11 | Aspion Co Ltd | EXTERNAL PREPARATION OF TYPE S / O |
WO2006112533A1 (en) * | 2005-04-18 | 2006-10-26 | Showa Denko K.K. | Water-containing gel form and production method thereof |
US20100323323A1 (en) * | 2005-06-24 | 2010-12-23 | Cao Group, Inc. | Pliable gingival isolation material |
US20090238763A1 (en) * | 2006-07-09 | 2009-09-24 | Chongxi Yu | High penetration compositions and uses thereof |
US20090221703A1 (en) | 2006-07-09 | 2009-09-03 | Chongxi Yu | High penetration composition and uses thereof |
EP2756843A3 (en) | 2006-07-25 | 2014-08-20 | Techfields Biochem Co. Ltd | Positively charged water-soluble prodrugs of diclofenac with very fast skin penetration rate |
BRPI0721709B1 (pt) | 2007-06-04 | 2024-03-12 | Techfields Inc. | PRÓ-FÁRMACOS DE NSAIAs, PROCESSO PARA PREPARAÇÃO DOS MESMOS, SEU USO, SISTEMAS TERAPÊUTICOS DE APLICAÇÃO TRANSDÉRMICA E COMPOSIÇÃO QUE OS COMPREENDE |
US7943668B2 (en) | 2008-03-03 | 2011-05-17 | Altergon S.A. | Process for preparing a pharmaceutical composition with anti-inflammatory and analgesic activity for administration via a patch for external use, and composition thus obtained |
WO2009109214A1 (en) * | 2008-03-03 | 2009-09-11 | Altergon S.A. | Process for preparing a pharmaceutical composition with anti-inflammatory and analgesic activity for administration via a patch for external use, and composition thus obtained |
CN104173321B (zh) * | 2008-03-03 | 2017-10-31 | 阿尔特根有限公司 | 制备通过外用贴剂给药的、具有消炎镇痛活性的药物组合物的方法,及以此获得的组合物 |
TWI383802B (zh) | 2008-12-04 | 2013-02-01 | Chongxi Yu | 高滲透性組合物及其應用 |
CN103357059B (zh) * | 2012-03-27 | 2016-08-03 | 上海卫生材料厂有限公司 | 几丁质凝胶创可贴 |
US10905669B2 (en) | 2015-02-20 | 2021-02-02 | Altergon S.A. | Effects of heparin on topical use of plasters containing a non-steroidal anti-inflammatory drug |
EP3173066A1 (en) * | 2015-11-25 | 2017-05-31 | Krzysztof Kubica | Plaster comprising antiedematous substances for the treatment of bruising and injury |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4855142A (en) * | 1987-02-27 | 1989-08-08 | Ciba-Geigy Corporation | Pharmaceutical plaster |
US4879282A (en) * | 1987-03-17 | 1989-11-07 | Saliba Jr Michael J | Medical application for heparin and related molecules |
US5041430A (en) * | 1989-09-18 | 1991-08-20 | Du Pont Mereck Pharmaceutical Company | Oral anticoagulant/platelet inhibitor low dose formulation |
US5217954A (en) * | 1990-04-04 | 1993-06-08 | Scios Nova Inc. | Formulations for stabilizing fibroblast growth factor |
JP2849937B2 (ja) * | 1990-04-18 | 1999-01-27 | 日東電工株式会社 | 医療用貼付剤 |
US5260066A (en) * | 1992-01-16 | 1993-11-09 | Srchem Incorporated | Cryogel bandage containing therapeutic agent |
IL101387A (en) * | 1992-03-26 | 1999-11-30 | Pharmos Ltd | Emulsion with enhanced topical and/or transdermal systemic effect utilizing submicron oil droplets |
JP3526887B2 (ja) * | 1993-04-23 | 2004-05-17 | 帝國製薬株式会社 | 消炎鎮痛外用貼付剤 |
US5668119A (en) * | 1996-02-22 | 1997-09-16 | Medenica; Rajko D. | Topical pharmaceutical containing heparin and method of treatment |
AU2953497A (en) * | 1996-05-13 | 1997-12-05 | Novartis Consumer Health S.A. | Topical composition |
GB2320431B (en) * | 1996-12-20 | 2000-08-30 | Johnson & Johnson Medical | Compositions for the treatment of chronic wounds |
-
1999
- 1999-04-21 IT IT1999MI000834A patent/IT1312088B1/it active
-
2000
- 2000-04-12 PT PT00107835T patent/PT1046395E/pt unknown
- 2000-04-12 ES ES00107835T patent/ES2244373T3/es not_active Expired - Lifetime
- 2000-04-12 AT AT00107835T patent/ATE297717T1/de active
- 2000-04-12 EP EP00107835A patent/EP1046395B1/en not_active Expired - Lifetime
- 2000-04-12 DK DK00107835T patent/DK1046395T3/da active
- 2000-04-12 DE DE60020768T patent/DE60020768T2/de not_active Expired - Lifetime
- 2000-04-14 US US09/549,254 patent/US6592891B1/en not_active Expired - Lifetime
- 2000-04-19 CA CA002306214A patent/CA2306214C/en not_active Expired - Lifetime
-
2003
- 2003-05-29 US US10/448,492 patent/US20030203017A1/en not_active Abandoned
-
2004
- 2004-10-04 US US10/957,031 patent/US7799338B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1046395A1 (en) | 2000-10-25 |
EP1046395B1 (en) | 2005-06-15 |
ES2244373T3 (es) | 2005-12-16 |
US20030203017A1 (en) | 2003-10-30 |
PT1046395E (pt) | 2005-10-31 |
CA2306214C (en) | 2009-10-20 |
IT1312088B1 (it) | 2002-04-04 |
CA2306214A1 (en) | 2000-10-21 |
DE60020768D1 (de) | 2005-07-21 |
US6592891B1 (en) | 2003-07-15 |
ITMI990834A1 (it) | 2000-10-21 |
ATE297717T1 (de) | 2005-07-15 |
US7799338B2 (en) | 2010-09-21 |
DE60020768T2 (de) | 2006-05-18 |
US20050048101A1 (en) | 2005-03-03 |
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