ATE297717T1 - Heparin und diclofenac enthaltendes topisches pflaster - Google Patents
Heparin und diclofenac enthaltendes topisches pflasterInfo
- Publication number
- ATE297717T1 ATE297717T1 AT00107835T AT00107835T ATE297717T1 AT E297717 T1 ATE297717 T1 AT E297717T1 AT 00107835 T AT00107835 T AT 00107835T AT 00107835 T AT00107835 T AT 00107835T AT E297717 T1 ATE297717 T1 AT E297717T1
- Authority
- AT
- Austria
- Prior art keywords
- diclofenac
- patch containing
- containing heparin
- topical patch
- heparin
- Prior art date
Links
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 title abstract 2
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 title abstract 2
- 229920000669 heparin Polymers 0.000 title abstract 2
- 229960002897 heparin Drugs 0.000 title abstract 2
- 230000000699 topical effect Effects 0.000 title abstract 2
- 229960001259 diclofenac Drugs 0.000 title 1
- 206010018852 Haematoma Diseases 0.000 abstract 2
- 229920001499 Heparinoid Polymers 0.000 abstract 1
- 239000012790 adhesive layer Substances 0.000 abstract 1
- 230000036592 analgesia Effects 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000002554 heparinoid Substances 0.000 abstract 1
- 239000000017 hydrogel Substances 0.000 abstract 1
- 239000010410 layer Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/402—Anaestetics, analgesics, e.g. lidocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
- A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Materials Engineering (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1999MI000834A IT1312088B1 (it) | 1999-04-21 | 1999-04-21 | Cerotto per uso topico contenente eparina e diclofenac. |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE297717T1 true ATE297717T1 (de) | 2005-07-15 |
Family
ID=11382783
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00107835T ATE297717T1 (de) | 1999-04-21 | 2000-04-12 | Heparin und diclofenac enthaltendes topisches pflaster |
Country Status (9)
Country | Link |
---|---|
US (3) | US6592891B1 (de) |
EP (1) | EP1046395B1 (de) |
AT (1) | ATE297717T1 (de) |
CA (1) | CA2306214C (de) |
DE (1) | DE60020768T2 (de) |
DK (1) | DK1046395T3 (de) |
ES (1) | ES2244373T3 (de) |
IT (1) | IT1312088B1 (de) |
PT (1) | PT1046395E (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0215068A (pt) | 2001-12-21 | 2004-11-09 | Coloplast As | Dispositivo para cuidar de feridas |
AU2003276707A1 (en) * | 2002-10-30 | 2004-05-25 | Showa Denko K.K. | Adhesive composition for dermal patch and production process thereof |
JP2004168764A (ja) * | 2002-10-30 | 2004-06-17 | Showa Denko Kk | 貼付剤用粘着剤組成物およびその製造方法 |
WO2005055945A2 (en) * | 2003-12-08 | 2005-06-23 | Gel-Del Technologies, Inc. | Mucoadhesive drug delivery devices and methods of making and using thereof |
EP1785131A4 (de) * | 2004-08-31 | 2009-03-11 | Aspion Co Ltd | Externe zubereitung vom s/o-typ |
WO2006112533A1 (en) * | 2005-04-18 | 2006-10-26 | Showa Denko K.K. | Water-containing gel form and production method thereof |
US20100323323A1 (en) * | 2005-06-24 | 2010-12-23 | Cao Group, Inc. | Pliable gingival isolation material |
US20090238763A1 (en) | 2006-07-09 | 2009-09-24 | Chongxi Yu | High penetration compositions and uses thereof |
US20090221703A1 (en) | 2006-07-09 | 2009-09-03 | Chongxi Yu | High penetration composition and uses thereof |
AU2006346759B2 (en) | 2006-07-25 | 2013-07-18 | Techfields Biochem Co. Ltd | Positively charged water-soluble prodrugs of diclofenac with very fast skin penetration rate |
CN101687792B (zh) | 2007-06-04 | 2016-03-02 | 于崇曦 | 具有快速皮肤和生物膜穿透速度的非甾体抗炎药的前药及其医药用途 |
US7943668B2 (en) | 2008-03-03 | 2011-05-17 | Altergon S.A. | Process for preparing a pharmaceutical composition with anti-inflammatory and analgesic activity for administration via a patch for external use, and composition thus obtained |
CN104173321B (zh) * | 2008-03-03 | 2017-10-31 | 阿尔特根有限公司 | 制备通过外用贴剂给药的、具有消炎镇痛活性的药物组合物的方法,及以此获得的组合物 |
ES2485491T3 (es) * | 2008-03-03 | 2014-08-13 | Altergon S.A. | Proceso para la preparación de una composición farmacéutica con actividad antiinflamatoria y analgésica para la administración mediante un parche para uso externo, y composición así obtenida |
CN108191846B (zh) | 2008-12-04 | 2021-08-20 | 于崇曦 | 高穿透性组合物及其应用 |
CN103357059B (zh) * | 2012-03-27 | 2016-08-03 | 上海卫生材料厂有限公司 | 几丁质凝胶创可贴 |
US10905669B2 (en) | 2015-02-20 | 2021-02-02 | Altergon S.A. | Effects of heparin on topical use of plasters containing a non-steroidal anti-inflammatory drug |
EP3173066A1 (de) * | 2015-11-25 | 2017-05-31 | Krzysztof Kubica | Pflaster mit antiödematösen substanzen zur behandlung von prellung und verletzung |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4855142A (en) * | 1987-02-27 | 1989-08-08 | Ciba-Geigy Corporation | Pharmaceutical plaster |
US4879282A (en) * | 1987-03-17 | 1989-11-07 | Saliba Jr Michael J | Medical application for heparin and related molecules |
US5041430A (en) * | 1989-09-18 | 1991-08-20 | Du Pont Mereck Pharmaceutical Company | Oral anticoagulant/platelet inhibitor low dose formulation |
US5217954A (en) * | 1990-04-04 | 1993-06-08 | Scios Nova Inc. | Formulations for stabilizing fibroblast growth factor |
JP2849937B2 (ja) * | 1990-04-18 | 1999-01-27 | 日東電工株式会社 | 医療用貼付剤 |
US5260066A (en) * | 1992-01-16 | 1993-11-09 | Srchem Incorporated | Cryogel bandage containing therapeutic agent |
IL101387A (en) * | 1992-03-26 | 1999-11-30 | Pharmos Ltd | Emulsion with enhanced topical and/or transdermal systemic effect utilizing submicron oil droplets |
JP3526887B2 (ja) * | 1993-04-23 | 2004-05-17 | 帝國製薬株式会社 | 消炎鎮痛外用貼付剤 |
US5668119A (en) * | 1996-02-22 | 1997-09-16 | Medenica; Rajko D. | Topical pharmaceutical containing heparin and method of treatment |
WO1997042944A1 (en) * | 1996-05-13 | 1997-11-20 | Novartis Consumer Health S.A. | Topical composition |
GB2320431B (en) * | 1996-12-20 | 2000-08-30 | Johnson & Johnson Medical | Compositions for the treatment of chronic wounds |
-
1999
- 1999-04-21 IT IT1999MI000834A patent/IT1312088B1/it active
-
2000
- 2000-04-12 EP EP00107835A patent/EP1046395B1/de not_active Expired - Lifetime
- 2000-04-12 AT AT00107835T patent/ATE297717T1/de active
- 2000-04-12 PT PT00107835T patent/PT1046395E/pt unknown
- 2000-04-12 ES ES00107835T patent/ES2244373T3/es not_active Expired - Lifetime
- 2000-04-12 DE DE60020768T patent/DE60020768T2/de not_active Expired - Lifetime
- 2000-04-12 DK DK00107835T patent/DK1046395T3/da active
- 2000-04-14 US US09/549,254 patent/US6592891B1/en not_active Expired - Lifetime
- 2000-04-19 CA CA002306214A patent/CA2306214C/en not_active Expired - Lifetime
-
2003
- 2003-05-29 US US10/448,492 patent/US20030203017A1/en not_active Abandoned
-
2004
- 2004-10-04 US US10/957,031 patent/US7799338B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2306214A1 (en) | 2000-10-21 |
ES2244373T3 (es) | 2005-12-16 |
ITMI990834A1 (it) | 2000-10-21 |
PT1046395E (pt) | 2005-10-31 |
US20050048101A1 (en) | 2005-03-03 |
DK1046395T3 (da) | 2005-10-03 |
DE60020768D1 (de) | 2005-07-21 |
CA2306214C (en) | 2009-10-20 |
DE60020768T2 (de) | 2006-05-18 |
US20030203017A1 (en) | 2003-10-30 |
IT1312088B1 (it) | 2002-04-04 |
US7799338B2 (en) | 2010-09-21 |
EP1046395B1 (de) | 2005-06-15 |
US6592891B1 (en) | 2003-07-15 |
EP1046395A1 (de) | 2000-10-25 |
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Legal Events
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UEP | Publication of translation of european patent specification |
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