DK1028117T3 - Hidtil ukendte protein:prenyltransferase-inhibitorer - Google Patents

Hidtil ukendte protein:prenyltransferase-inhibitorer

Info

Publication number
DK1028117T3
DK1028117T3 DK00200372T DK00200372T DK1028117T3 DK 1028117 T3 DK1028117 T3 DK 1028117T3 DK 00200372 T DK00200372 T DK 00200372T DK 00200372 T DK00200372 T DK 00200372T DK 1028117 T3 DK1028117 T3 DK 1028117T3
Authority
DK
Denmark
Prior art keywords
hydrogen
alkyl
optionally substituted
new protein
prenyltransferase inhibitors
Prior art date
Application number
DK00200372T
Other languages
English (en)
Inventor
Herman Steven Overkleeft
Steven Hendrik Leonar Verhelst
Nicolaas Johannes Meeuwenoord
Elsbet Jantine Pieterman
Louis Hartog Cohen
Mark Overhand
Der Marel Gijsbert Arie Van
Boom Jocobus Hubertus Van
Original Assignee
Tno
Univ Leiden
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno, Univ Leiden filed Critical Tno
Application granted granted Critical
Publication of DK1028117T3 publication Critical patent/DK1028117T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pyrane Compounds (AREA)
DK00200372T 1999-02-03 2000-02-03 Hidtil ukendte protein:prenyltransferase-inhibitorer DK1028117T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99200316 1999-02-03

Publications (1)

Publication Number Publication Date
DK1028117T3 true DK1028117T3 (da) 2002-09-16

Family

ID=8239861

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00200372T DK1028117T3 (da) 1999-02-03 2000-02-03 Hidtil ukendte protein:prenyltransferase-inhibitorer

Country Status (7)

Country Link
US (1) US6376468B1 (da)
EP (1) EP1028117B1 (da)
JP (1) JP2000226383A (da)
AT (1) ATE219072T1 (da)
DE (1) DE60000203T2 (da)
DK (1) DK1028117T3 (da)
ES (1) ES2174794T3 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8013014B2 (en) * 2002-07-05 2011-09-06 Georgia Tech Research Corporation Aza-peptide epoxides
US7056947B2 (en) * 2002-07-05 2006-06-06 Georgia Tech Research Corp. Aza-peptide epoxides
US7482379B2 (en) * 2004-02-18 2009-01-27 Georgia Tech Research Corporation Propenoyl hydrazides
US20060014939A1 (en) * 2004-07-15 2006-01-19 Chakraborty Tushar K Novel C6-substituted furanoid sugar amino acids and improved process for preparing the same
US20090183503A1 (en) * 2008-01-18 2009-07-23 Alberto Verdesi Exhaust apparatus
WO2009148709A1 (en) * 2008-04-16 2009-12-10 University Of Utah Research Foundation Pharmacological targeting of vascular malformations

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6673927B2 (en) * 1996-02-16 2004-01-06 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Farnesyl transferase inhibitors

Also Published As

Publication number Publication date
US6376468B1 (en) 2002-04-23
ATE219072T1 (de) 2002-06-15
EP1028117B1 (en) 2002-06-12
JP2000226383A (ja) 2000-08-15
EP1028117A3 (en) 2000-08-23
EP1028117A2 (en) 2000-08-16
DE60000203D1 (de) 2002-07-18
ES2174794T3 (es) 2002-11-16
DE60000203T2 (de) 2003-02-06

Similar Documents

Publication Publication Date Title
CO5570660A2 (es) Indazolilpirrolotriazinas c-6 modificadas
EA200200299A1 (ru) НОВЫЕ α-АМИНОКИСЛОТНЫЕ СУЛЬФОНИЛЬНЫЕ СОЕДИНЕНИЯ, СПОСОБ ИХ ПОЛУЧЕНИЯ И ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ ИХ СОДЕРЖАЩИЕ
ATE530614T1 (de) Neues hydrogelbildendes mittel auf lipid- tripeptid-basis und hydrogel
DK1265606T3 (da) Celleadhæsionsinhibitorer
HUP0002942A2 (hu) Szerin proteáz inhibitor hatású peptidek, ezeket hatóanyagként tartalmazó gyógyászati készítmények és alkalmazásuk
EP1052254A4 (en) NITROGENIC HETEROCYCLIC DERIVATIVES AND DRUGS PRODUCED FROM SUCH DERIVATIVES
CO5700773A2 (es) Derivados de bencimidazol
HK1050324A1 (en) Stabilized pharmaceutical composition containing the calcium channel blocker azelnidipine
AR024364A1 (es) Una composicion cosmetica para el adelgazamiento a base l-arginina, de un analogo de l-arginina, o de uno de sus derivados, que se administra por viatopica
AR029145A1 (es) Compuesto de hidroxamato pirrolidina sustituida, inhibidores de metaloproteasa, composicion farmaceutica que lo comprende y uso para elaborar una composicion farmaceutica
ATE297945T1 (de) Glutathionderivate und dazugehörige dosisformen
DK1028117T3 (da) Hidtil ukendte protein:prenyltransferase-inhibitorer
NZ242108A (en) Azadecalin amides and thioamides, and pharmaceutical compositions
HK1051712A1 (en) Acidic treatment liquid and method of treating copper surfaces.
RU2008151775A (ru) Способы сайт-специфического пегилирования
WO2004026896A3 (en) Hcv ns-3 serine protease inhibitors
ATE380172T1 (de) Benzylaminanalogen
BG105123A (en) Tetrahydroquinaline derivatives as glycine antagonists
DE69415314D1 (de) Neue bisoxadiazolidinderivate
DE69940551D1 (de) Mercaptane und disulfide
DK1140942T3 (da) Prenyltransferaseinhibitorer
ATE356112T1 (de) Thio-derivate als würzende bestandteile
BR0107204A (pt) Inibidores da angiogênese de hidrazida e alcoxiamida
DK1144421T3 (da) Phosphiniske pseudopeptider, som er inhibitorer af matrix-metalloproteaser
WO1998046276A8 (en) Chelating agents