DK0999849T3 - Anvendelse af LBP til sepsisbehandling - Google Patents

Anvendelse af LBP til sepsisbehandling

Info

Publication number
DK0999849T3
DK0999849T3 DK98928139T DK98928139T DK0999849T3 DK 0999849 T3 DK0999849 T3 DK 0999849T3 DK 98928139 T DK98928139 T DK 98928139T DK 98928139 T DK98928139 T DK 98928139T DK 0999849 T3 DK0999849 T3 DK 0999849T3
Authority
DK
Denmark
Prior art keywords
lbp
therapeutic agent
sepsis treatment
treatment
septicemia
Prior art date
Application number
DK98928139T
Other languages
Danish (da)
English (en)
Inventor
Ralf Reiner Schumann
Norbert Lamping
Original Assignee
Max Delbrueck Centrum
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Delbrueck Centrum filed Critical Max Delbrueck Centrum
Application granted granted Critical
Publication of DK0999849T3 publication Critical patent/DK0999849T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1751—Bactericidal/permeability-increasing protein [BPI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
DK98928139T 1997-07-11 1998-04-04 Anvendelse af LBP til sepsisbehandling DK0999849T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19729810A DE19729810C2 (de) 1997-07-11 1997-07-11 Mittel zur Sepsistherapie, seine Herstellung und seine Verwendung
PCT/DE1998/000964 WO1999002178A1 (fr) 1997-07-11 1998-04-04 Agent therapeutique pour le traitement de la septicemie, sa preparation et son utilisation

Publications (1)

Publication Number Publication Date
DK0999849T3 true DK0999849T3 (da) 2003-01-06

Family

ID=7835437

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98928139T DK0999849T3 (da) 1997-07-11 1998-04-04 Anvendelse af LBP til sepsisbehandling

Country Status (9)

Country Link
US (1) US6949512B1 (fr)
EP (1) EP0999849B1 (fr)
JP (1) JP2001509488A (fr)
AT (1) ATE223227T1 (fr)
DE (2) DE19729810C2 (fr)
DK (1) DK0999849T3 (fr)
ES (1) ES2183376T3 (fr)
PT (1) PT999849E (fr)
WO (1) WO1999002178A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2108372A1 (fr) * 2008-04-09 2009-10-14 Forschungszentrum Borstel Leibniz-Zentrum für Medizin und Biowissenschaften Nouveaux peptides antimicrobiens

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2161971A1 (fr) * 1993-04-30 1994-11-10 Randal W. Scott Proteines recombinantes a base de bpi et de lbp; molecules d'acide nucleique codant ces proteines; methodes de preparation et utilisations
WO1995005393A2 (fr) * 1993-08-18 1995-02-23 Morphosys Gesellschaft Für Proteinoptimierung Mbh Peptides liant et neturalisant les lipopolysaccharides
WO1995008560A1 (fr) * 1993-09-24 1995-03-30 Centocor, Inc. Nouveaux peptides destines a inhiber la liaison de lipopolysaccharides (lps) par une proteine de liaison de lipopolysaccharides (lbp)
US5837810A (en) * 1994-03-15 1998-11-17 The Scripps Research Institute Polypeptides of lipopolysaccharide binding protein
US5990082A (en) * 1997-10-22 1999-11-23 Xoma Corporation Uses of lipopolysaccharide binding protein

Also Published As

Publication number Publication date
WO1999002178A1 (fr) 1999-01-21
DE19729810A1 (de) 1999-01-14
US6949512B1 (en) 2005-09-27
EP0999849A1 (fr) 2000-05-17
JP2001509488A (ja) 2001-07-24
DE59805440D1 (de) 2002-10-10
EP0999849B1 (fr) 2002-09-04
ES2183376T3 (es) 2003-03-16
ATE223227T1 (de) 2002-09-15
PT999849E (pt) 2003-01-31
DE19729810C2 (de) 2000-01-13

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