DK0967862T3 - Fremgangsmåde og præparater til fremstilling af tørrede, lagringsstabile blodplader - Google Patents

Fremgangsmåde og præparater til fremstilling af tørrede, lagringsstabile blodplader

Info

Publication number
DK0967862T3
DK0967862T3 DK98904260T DK98904260T DK0967862T3 DK 0967862 T3 DK0967862 T3 DK 0967862T3 DK 98904260 T DK98904260 T DK 98904260T DK 98904260 T DK98904260 T DK 98904260T DK 0967862 T3 DK0967862 T3 DK 0967862T3
Authority
DK
Denmark
Prior art keywords
compositions
methods
storage
preparing dried
platelets
Prior art date
Application number
DK98904260T
Other languages
English (en)
Inventor
Diana Johanna Phipps
Bruce Joseph Roser
Valentine Charlton Menys
Lynda Mary Grandage
Original Assignee
Elan Drug Delivery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Drug Delivery Ltd filed Critical Elan Drug Delivery Ltd
Application granted granted Critical
Publication of DK0967862T3 publication Critical patent/DK0967862T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331—Preservative, buffer, anticoagulant or diluent

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK98904260T 1997-02-07 1998-02-06 Fremgangsmåde og præparater til fremstilling af tørrede, lagringsstabile blodplader DK0967862T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3749397P 1997-02-07 1997-02-07
PCT/GB1998/000375 WO1998034478A1 (en) 1997-02-07 1998-02-06 Methods and compositions for producing dried, storage-stable platelets

Publications (1)

Publication Number Publication Date
DK0967862T3 true DK0967862T3 (da) 2003-05-12

Family

ID=21894636

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98904260T DK0967862T3 (da) 1997-02-07 1998-02-06 Fremgangsmåde og præparater til fremstilling af tørrede, lagringsstabile blodplader

Country Status (12)

Country Link
US (1) US6221575B1 (da)
EP (1) EP0967862B1 (da)
JP (1) JP2001511174A (da)
CN (1) CN1246778A (da)
AT (1) ATE230923T1 (da)
AU (1) AU732274B2 (da)
CA (1) CA2279376A1 (da)
DE (1) DE69810755T2 (da)
DK (1) DK0967862T3 (da)
ES (1) ES2190063T3 (da)
WO (1) WO1998034478A1 (da)
ZA (1) ZA981031B (da)

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GB9914412D0 (en) * 1999-06-22 1999-08-18 Worrall Eric E Method for the preservation of viruses,bacteria and biomolecules
US6833236B1 (en) 1999-11-12 2004-12-21 Quadrant Drug Delivery Ltd. Platelet stabilization
DE19964109A1 (de) 1999-12-29 2001-07-05 Dade Behring Marburg Gmbh Gebrauchsfertiges langzeitstabiles Ristocetin Cofaktor Testreagenz
AU2001234978A1 (en) * 2000-02-10 2001-08-20 The Regents Of The University Of California Therapeutic platelets and methods
DE10010959A1 (de) * 2000-03-06 2001-09-20 Eppendorf Geraetebau Netheler Verfahren zum Übertragen von Material in einem Zellsystem
US6653062B1 (en) * 2000-07-26 2003-11-25 Wisconsin Alumni Research Foundation Preservation and storage medium for biological materials
US7011852B2 (en) * 2001-05-07 2006-03-14 Hemogenesis, Llc Separation of platelets from whole blood for use as a healant
US8101077B2 (en) * 2001-05-07 2012-01-24 Sivaprasad Sukavaneshvar Device for separating platelets from fluid suspensions
WO2004011616A2 (en) * 2002-07-26 2004-02-05 The General Hospital Corporation Systems and methods for cell preservation
WO2005002499A2 (en) * 2002-11-29 2005-01-13 The Regents Of The University Of California A method and therapeutic platelets
EP1758937B1 (en) * 2004-05-24 2009-09-02 Genvault Corporation Stable protein storage and stable nucleic acid storage in recoverable form
US20060035383A1 (en) * 2004-08-12 2006-02-16 David Ho Dry platelet preparations for use in diagnostics
US7811558B2 (en) * 2004-08-12 2010-10-12 Cellphire, Inc. Use of stabilized platelets as hemostatic agent
AU2005272821B2 (en) * 2004-08-12 2010-09-09 Cellphire, Inc Methods for preparing freeze-dried platelets, compositions comprising freeze-dried platelets, and methods of use
EP1954252B1 (en) * 2005-12-02 2016-02-03 GlaxoSmithKline Biologicals SA Nanoparticles for use in immunogenic compositions
US8097403B2 (en) * 2006-12-14 2012-01-17 Cellphire, Inc. Freeze-dried platelets, method of making and method of use as a diagnostic agent
US20090081785A1 (en) * 2007-09-24 2009-03-26 Hememics Biotechnologies, Inc. Desiccated Biologics And Methods Of Preparing The Same
US20090090022A1 (en) * 2007-10-09 2009-04-09 Hememics Biotechnologies, Inc. Desiccation Chamber and Methods for Drying Biological Materials
US20100209957A1 (en) * 2008-06-20 2010-08-19 Genvault Corporation Biosample storage devices and methods of use thereof
CN102177237B (zh) * 2008-09-12 2013-10-30 金沃特公司 用于贮存和稳定生物分子的基质和介质
US8734854B2 (en) * 2009-07-09 2014-05-27 Orogen Biosciences Inc. Process for removing growth factors from platelets
US20110183311A1 (en) * 2010-01-27 2011-07-28 David Ho Dry platelet preparations for use in diagnostics
US9943075B2 (en) * 2010-02-17 2018-04-17 Hememics Biotechnologies, Inc. Preservation solutions for biologics and methods related thereto
WO2011124280A1 (en) * 2010-04-08 2011-10-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Zeodration method for the preservation of blood platelets
CN101957364A (zh) * 2010-09-19 2011-01-26 李勇 冻干型血小板抗原谱细胞的制备方法
CN102327288B (zh) * 2011-10-17 2012-11-14 济南环肽医药科技有限公司 一种注射用血小板冻干粉制剂及其制备方法
JP6659591B2 (ja) 2014-06-09 2020-03-04 テルモ ビーシーティー、インコーポレーテッド 凍結乾燥
CN104964909B (zh) * 2015-05-28 2018-04-24 上海市血液中心 一种血小板跨膜电位检测方法
US10448631B2 (en) 2015-09-22 2019-10-22 East Carolina University Cryopreservation using sucralose
US10793327B2 (en) 2017-10-09 2020-10-06 Terumo Bct Biotechnologies, Llc Lyophilization container and method of using same
EP3887404A4 (en) 2018-11-30 2022-11-02 Cellphire, Inc. SLIDES LOADED WITH ANTI-CANCER AGENTS
EP3886879A4 (en) 2018-11-30 2022-12-07 Cellphire Inc. PLATES AS DELIVERY AGENTS
CA3130700A1 (en) 2019-03-14 2020-09-17 Terumo Bct Biotechnologies, Llc Lyophilization container fill fixture, system and method of use
SG11202112054WA (en) 2019-05-03 2021-11-29 Cellphire Inc Materials and methods for producing blood products
EP4013432A4 (en) * 2019-08-16 2023-10-18 Cellphire Inc. THROMBOSOMES AS AN ANTICOAGULANT REVERSAL AGENT
BR112022002892A2 (pt) * 2019-08-16 2022-05-24 Cellphire Inc Trombossomos como um agente de reversão de agente antiplaqueta
WO2021158622A1 (en) 2020-02-04 2021-08-12 Cellphire, Inc. Anti-fibrinolytic loaded platelets

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4251995A (en) * 1979-04-25 1981-02-24 Hedbergska Stiftelsen Method of freezing human blood platelets in glycerol-glucose using a statically controlled cooling rate device
CH660634A5 (de) 1983-08-30 1987-05-15 Dimitrios Giannitsis Verfahren zur herstellung von natuerlichem immunoadsorbens.
WO1987000196A1 (en) 1985-07-09 1987-01-15 Quadrant Bioresources Limited Protection of proteins and the like
JPS62501631A (ja) * 1985-01-11 1987-07-02 ザ・リ−ジェンツ・オブ・ジ・ユニバ−シィティ・オブ・カリフォルニア リポソ−ムの保持法
GB8604983D0 (en) * 1986-02-28 1986-04-09 Biocompatibles Ltd Protein preservation
GB8715238D0 (en) 1987-06-29 1987-08-05 Quadrant Bioresources Ltd Food process
GB8801338D0 (en) 1988-01-21 1988-02-17 Quadrant Bioresources Ltd Preservation of viruses
US5045446A (en) 1988-08-26 1991-09-03 Cryopharm Corporation Lyophilization of cells
US5958670A (en) * 1988-05-18 1999-09-28 Cobe Laboratories, Inc. Method of freezing cells and cell-like materials
US5059518A (en) * 1988-10-20 1991-10-22 Coulter Corporation Stabilized lyophilized mammalian cells and method of making same
US5332578A (en) 1989-04-14 1994-07-26 Prp, Inc. Platelet membrane microparticles
US5428008A (en) 1989-04-14 1995-06-27 Prp, Inc. Therapeutic composition of micellar structures capable of promoting hemotasis
US5242792A (en) 1991-02-25 1993-09-07 The United States Of America As Represented By The Secretary Of The Navy Method for the preservation of red blood cells by lyophilization using glycerol or inositol with disaccharides
GB9114202D0 (en) 1991-07-01 1991-08-21 Quadrant Holdings Cambridge Blood products
WO1993014191A1 (en) 1992-01-21 1993-07-22 Cryopharm Corporation Method of freezing cells and cell-like materials
EP0642301B1 (en) * 1992-05-29 2003-03-12 The University Of North Carolina At Chapel Hill Pharmaceutically acceptable fixed-dried human blood platelets
JPH06154318A (ja) 1992-11-25 1994-06-03 Fukuda Sangyo Kaihatsu Center Kk 点滴用輸液量測定装置
US5656498A (en) 1994-02-22 1997-08-12 Nippon Telegraph And Telephone Corporation Freeze-dried blood cells, stem cells and platelets, and manufacturing method for the same
JPH0920687A (ja) 1995-07-03 1997-01-21 Nippon Telegr & Teleph Corp <Ntt> 凍結乾燥血液の戻し液
US5827741A (en) * 1996-11-19 1998-10-27 The Regents Of The University Of California Cryopreservation of human adult and fetal pancreatic cells and human platelets

Also Published As

Publication number Publication date
DE69810755D1 (de) 2003-02-20
ZA981031B (en) 1998-08-11
EP0967862B1 (en) 2003-01-15
WO1998034478A1 (en) 1998-08-13
DE69810755T2 (de) 2003-08-07
AU732274B2 (en) 2001-04-12
US6221575B1 (en) 2001-04-24
ES2190063T3 (es) 2003-07-16
CN1246778A (zh) 2000-03-08
AU6220898A (en) 1998-08-26
EP0967862A1 (en) 2000-01-05
JP2001511174A (ja) 2001-08-07
ATE230923T1 (de) 2003-02-15
CA2279376A1 (en) 1998-08-13

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