DK0950100T3 - Keratinocytvækstfaktor-2- (KGF-2- eller fibroblastvækstfaktor-12-, FGF-12-) mutanter - Google Patents
Keratinocytvækstfaktor-2- (KGF-2- eller fibroblastvækstfaktor-12-, FGF-12-) mutanterInfo
- Publication number
- DK0950100T3 DK0950100T3 DK97937200T DK97937200T DK0950100T3 DK 0950100 T3 DK0950100 T3 DK 0950100T3 DK 97937200 T DK97937200 T DK 97937200T DK 97937200 T DK97937200 T DK 97937200T DK 0950100 T3 DK0950100 T3 DK 0950100T3
- Authority
- DK
- Denmark
- Prior art keywords
- growth factor
- kgf
- polynucleotides
- polypeptides
- fgf
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factors [FGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2385296P | 1996-08-13 | 1996-08-13 | |
US3904597P | 1997-02-28 | 1997-02-28 | |
PCT/US1997/014112 WO1998006844A1 (en) | 1996-08-13 | 1997-08-13 | Keratinocyte growth factor-2 (kgf-2 or fibroblast growth factor-12, kgf-12) |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0950100T3 true DK0950100T3 (da) | 2004-06-07 |
Family
ID=26697695
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97937200T DK0950100T3 (da) | 1996-08-13 | 1997-08-13 | Keratinocytvækstfaktor-2- (KGF-2- eller fibroblastvækstfaktor-12-, FGF-12-) mutanter |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0950100B1 (da) |
JP (1) | JP2000517174A (da) |
KR (1) | KR20000029986A (da) |
CN (1) | CN1234071A (da) |
AT (1) | ATE259420T1 (da) |
AU (1) | AU739773B2 (da) |
CA (1) | CA2263143A1 (da) |
DE (1) | DE69727589T2 (da) |
DK (1) | DK0950100T3 (da) |
ES (1) | ES2212121T3 (da) |
NZ (1) | NZ333725A (da) |
PT (1) | PT950100E (da) |
WO (1) | WO1998006844A1 (da) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5932540A (en) | 1994-03-08 | 1999-08-03 | Human Genome Sciences, Inc. | Vascular endothelial growth factor 2 |
US6040157A (en) * | 1994-03-08 | 2000-03-21 | Human Genome Sciences, Inc. | Vascular endothelial growth factor 2 |
US7109308B1 (en) | 1994-03-08 | 2006-09-19 | Human Genome Sciences, Inc. | Antibodies to human vascular endothelial growth factor 2 |
US6608182B1 (en) | 1994-03-08 | 2003-08-19 | Human Genome Sciences, Inc. | Human vascular endothelial growth factor 2 |
WO1995024473A1 (en) | 1994-03-08 | 1995-09-14 | Human Genome Sciences, Inc. | Vascular endothelial growth factor 2 |
US6734285B2 (en) | 1994-03-08 | 2004-05-11 | Human Genome Sciences, Inc. | Vascular endothelial growth factor 2 proteins and compositions |
US7153827B1 (en) | 1994-03-08 | 2006-12-26 | Human Genome Sciences, Inc. | Vascular endothelial growth factor 2 and methods of use |
US7186688B1 (en) | 1994-03-08 | 2007-03-06 | Human Genome Sciences, Inc. | Methods of stimulating angiogenesis in a patient by administering vascular endothelial growth factor 2 |
US7232667B2 (en) | 1995-02-14 | 2007-06-19 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 polynucleotides |
US6077692A (en) | 1995-02-14 | 2000-06-20 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 |
US6693077B1 (en) | 1995-02-14 | 2004-02-17 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 |
AU775027C (en) * | 1996-10-15 | 2005-12-08 | Biovitrum Ab (Publ) | Keratinocyte growth factor-2 products |
CA2269077C (en) * | 1996-10-15 | 2004-04-06 | Amgen Inc. | Keratinocyte growth factor-2 products |
US6743422B1 (en) | 1996-10-15 | 2004-06-01 | Amgen, Inc. | Keratinocyte growth factor-2 products |
EP1473366A1 (en) * | 1996-10-15 | 2004-11-03 | Amgen Inc. | Keratinocyte growth factor-2 products |
EP1041996A4 (en) * | 1997-12-22 | 2003-05-14 | Human Genome Sciences Inc | KERATINOCYTE GROWTH FACTOR-2 FORMULATIONS |
US6869927B1 (en) | 1997-12-22 | 2005-03-22 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 formulations |
CA2320515A1 (en) * | 1998-02-13 | 1999-08-19 | Human Genome Sciences, Inc. | Therapeutic uses of keratinocyte growth factor-2 |
JP2002505873A (ja) * | 1998-03-13 | 2002-02-26 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | 血管内皮増殖因子2 |
US7223724B1 (en) | 1999-02-08 | 2007-05-29 | Human Genome Sciences, Inc. | Use of vascular endothelial growth factor to treat photoreceptor cells |
JP2003524402A (ja) * | 1999-05-14 | 2003-08-19 | キュラジェン コーポレイション | 新規のポリヌクレオチドおよびそれによりコードされるポリペプチド |
EP1196187A4 (en) * | 1999-06-02 | 2003-02-05 | Human Genome Sciences Inc | KERATINOCYTARY 2 GROWTH FECTOR FORMULATIONS |
US7273751B2 (en) | 2000-08-04 | 2007-09-25 | Human Genome Science, Inc. | Vascular endothelial growth factor-2 |
AU2002309473A1 (en) * | 2001-01-08 | 2002-10-08 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 |
ATE470676T1 (de) | 2001-04-13 | 2010-06-15 | Human Genome Sciences Inc | Anti-vegf-2 antikörper |
US7402312B2 (en) | 2001-04-13 | 2008-07-22 | Human Genome Sciences, Inc. | Antibodies to vascular endothelial growth factor 2 (VEGF-2) |
US8871709B2 (en) * | 2003-02-05 | 2014-10-28 | Queensland University of Technolgy | Synthetic chimeric proteins comprising epidermal growth factor and vitronectin |
CN107041948A (zh) * | 2009-01-21 | 2017-08-15 | 北京三有利科技发展有限公司 | 细胞生长因子治疗溃疡性疾病和肺纤维化疾病的应用 |
ES2626327T3 (es) | 2009-02-06 | 2017-07-24 | The Regents Of The University Of California | Agentes enlazantes de calcio que inducen crecimiento del cabello y/o crecimiento de las uñas |
CN102727890A (zh) * | 2012-07-05 | 2012-10-17 | 吉林农业大学 | 抗重组人角质细胞生长因子-2抗体的应用 |
JP2016535770A (ja) | 2013-11-01 | 2016-11-17 | スフェリウム バイオメッド エス.エル. | 治療用及び美容用物質を経皮送達するための封入体 |
CN104474533A (zh) * | 2014-11-24 | 2015-04-01 | 华南理工大学 | 一种可用于创面修复的复合微球的制备方法 |
CN104593320B (zh) * | 2015-01-04 | 2017-05-17 | 许永安 | 一种汗腺分化诱导培养基及其应用 |
US9597274B2 (en) * | 2015-06-17 | 2017-03-21 | Avon Products, Inc. | Peptides and their use in the treatment of skin |
CN109402130A (zh) * | 2018-11-23 | 2019-03-01 | 成都中医药大学附属医院 | 一种重组人角质细胞生长因子-1及其制备方法和用途 |
CN111588837B (zh) * | 2020-05-14 | 2023-06-06 | 中南大学湘雅三医院 | 一种蛋白-纳米银复合物的制备方法及制备的复合物和用途 |
KR102440312B1 (ko) * | 2020-08-28 | 2022-09-05 | 한국해양과학기술원 | 온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도 |
CN112675294B (zh) * | 2021-03-12 | 2021-05-14 | 诺赛联合(北京)生物医学科技有限公司 | 一种成纤维细胞的制备及在整形外科修复中的应用 |
WO2022204331A1 (en) * | 2021-03-24 | 2022-09-29 | Combangio, Inc. | Compositions comprising branched kgf-2 derived peptides and methods for use in ocular treatment |
EP4183796A1 (en) | 2021-11-19 | 2023-05-24 | Enantis s.r.o. | Thermostable fgf10 polypeptide or fragment thereof use thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1323824A3 (en) * | 1995-02-14 | 2004-01-21 | Human Genome Sciences, Inc. | Use of human keratinocyte growth factor-2 for the preparation of pharmaceutical compositions |
CA2269077C (en) * | 1996-10-15 | 2004-04-06 | Amgen Inc. | Keratinocyte growth factor-2 products |
-
1997
- 1997-08-13 WO PCT/US1997/014112 patent/WO1998006844A1/en not_active Application Discontinuation
- 1997-08-13 CA CA002263143A patent/CA2263143A1/en not_active Abandoned
- 1997-08-13 CN CN97197264A patent/CN1234071A/zh active Pending
- 1997-08-13 JP JP10509953A patent/JP2000517174A/ja not_active Withdrawn
- 1997-08-13 PT PT97937200T patent/PT950100E/pt unknown
- 1997-08-13 KR KR1019997001249A patent/KR20000029986A/ko not_active Application Discontinuation
- 1997-08-13 AU AU39770/97A patent/AU739773B2/en not_active Ceased
- 1997-08-13 DK DK97937200T patent/DK0950100T3/da active
- 1997-08-13 DE DE69727589T patent/DE69727589T2/de not_active Revoked
- 1997-08-13 ES ES97937200T patent/ES2212121T3/es not_active Expired - Lifetime
- 1997-08-13 AT AT97937200T patent/ATE259420T1/de not_active IP Right Cessation
- 1997-08-13 NZ NZ333725A patent/NZ333725A/xx unknown
- 1997-08-13 EP EP97937200A patent/EP0950100B1/en not_active Revoked
Also Published As
Publication number | Publication date |
---|---|
ES2212121T3 (es) | 2004-07-16 |
EP0950100B1 (en) | 2004-02-11 |
AU3977097A (en) | 1998-03-06 |
NZ333725A (en) | 2000-10-27 |
DE69727589T2 (de) | 2004-08-05 |
AU739773B2 (en) | 2001-10-18 |
CN1234071A (zh) | 1999-11-03 |
ATE259420T1 (de) | 2004-02-15 |
PT950100E (pt) | 2004-06-30 |
WO1998006844A1 (en) | 1998-02-19 |
EP0950100A1 (en) | 1999-10-20 |
DE69727589D1 (de) | 2004-03-18 |
CA2263143A1 (en) | 1998-02-19 |
JP2000517174A (ja) | 2000-12-26 |
KR20000029986A (ko) | 2000-05-25 |
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