DK0941219T3 - Mellemprodukt til anvendelse ved docetaxelsyntese og fremstillingsmetode derfor - Google Patents

Mellemprodukt til anvendelse ved docetaxelsyntese og fremstillingsmetode derfor

Info

Publication number
DK0941219T3
DK0941219T3 DK97906792T DK97906792T DK0941219T3 DK 0941219 T3 DK0941219 T3 DK 0941219T3 DK 97906792 T DK97906792 T DK 97906792T DK 97906792 T DK97906792 T DK 97906792T DK 0941219 T3 DK0941219 T3 DK 0941219T3
Authority
DK
Denmark
Prior art keywords
baccatin iii
deacetyl baccatin
manufacturing
intermediate product
docetaxel
Prior art date
Application number
DK97906792T
Other languages
Danish (da)
English (en)
Inventor
Charles S Swindell
Nicholas J Sisti
Madhavi C Chander
Original Assignee
Napro Biotherapeutics Inc
Bryn Mawr College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27085951&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0941219(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Napro Biotherapeutics Inc, Bryn Mawr College filed Critical Napro Biotherapeutics Inc
Application granted granted Critical
Publication of DK0941219T3 publication Critical patent/DK0941219T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK97906792T 1996-02-29 1997-02-27 Mellemprodukt til anvendelse ved docetaxelsyntese og fremstillingsmetode derfor DK0941219T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60908396A 1996-02-29 1996-02-29
US08/616,466 US6107497A (en) 1996-02-29 1996-03-19 Intermediate for use in docetaxel synthesis and production method therefor
PCT/US1997/003120 WO1997031911A1 (en) 1996-02-29 1997-02-27 Intermediate for use in docetaxel synthesis and production method therefor

Publications (1)

Publication Number Publication Date
DK0941219T3 true DK0941219T3 (da) 2002-12-16

Family

ID=27085951

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97906792T DK0941219T3 (da) 1996-02-29 1997-02-27 Mellemprodukt til anvendelse ved docetaxelsyntese og fremstillingsmetode derfor

Country Status (14)

Country Link
US (1) US6107497A (de)
EP (1) EP0941219B1 (de)
JP (1) JP2001526626A (de)
AT (1) ATE222247T1 (de)
AU (1) AU723968B2 (de)
CA (1) CA2246541C (de)
DE (1) DE69714761T2 (de)
DK (1) DK0941219T3 (de)
EA (2) EA001385B1 (de)
ES (1) ES2180943T3 (de)
GE (1) GEP20002270B (de)
PL (1) PL328578A1 (de)
PT (1) PT941219E (de)
WO (1) WO1997031911A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1082316E (pt) * 1998-05-01 2004-11-30 Napro Biotherapeutics Inc Processos e intermediarios uteis para a sintese de paclitaxel a partir de c-7,c-10-di-cbz-bacatina iii
US6358996B1 (en) 2000-06-09 2002-03-19 Napro Biotherapeutics, Inc. Stable isotope labeling of paclitaxel
WO2002076448A1 (en) * 2001-03-23 2002-10-03 Napro Biotherapeutics, Inc. Molecular conjugates for use in treatment of cancer
US6653501B2 (en) 2001-06-27 2003-11-25 Napro Biotherapeutics, Inc. Chiral resolution method for producing compounds useful in the synthesis of taxanes
CN1268619C (zh) * 2003-05-08 2006-08-09 上海迪赛诺化学制药有限公司 多烯紫杉醇三水化合物的制备方法
US7202370B2 (en) * 2003-10-27 2007-04-10 Conor Medsystems, Inc. Semi-synthesis of taxane intermediates from 9-dihydro-13-acetylbaccatin III
JP2005202893A (ja) * 2004-01-19 2005-07-28 Hitachi Ltd 記憶デバイス制御装置、ストレージシステム、プログラムを記録した記録媒体、情報処理装置、及びストレージシステムの制御方法
US20090156828A1 (en) * 2005-12-21 2009-06-18 Tapestry Pharmaceuticals, Inc. Novel Compounds and Methods for Forming Taxanes and Using the Same
RU2008142363A (ru) * 2006-03-27 2010-05-10 Тэпистри Фармасьютикалз, Инк. (Us) Конвергентный способ синтеза таксановых производных

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US34277A (en) * 1862-01-28 Improvement in lamps
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2629819B1 (fr) * 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
USRE34277E (en) 1988-04-06 1993-06-08 Centre National De La Recherche Scientifique Process for preparing taxol
US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5015744A (en) * 1989-11-14 1991-05-14 Florida State University Method for preparation of taxol using an oxazinone
US5136060A (en) * 1989-11-14 1992-08-04 Florida State University Method for preparation of taxol using an oxazinone
FR2680506B1 (fr) * 1991-08-19 1994-09-02 Rhone Poulenc Rorer Sa Procede de preparation de derives de la beta-phenylisoserine et leur utilisation.
US5399726A (en) * 1993-01-29 1995-03-21 Florida State University Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups
FR2687151B1 (fr) * 1992-02-07 1994-03-25 Rhone Poulenc Rorer Sa Nouveaux derives de la baccatine iii et de la desacetyl-10 baccatine iii, leur preparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
EA199800780A1 (ru) 1999-02-25
EP0941219A1 (de) 1999-09-15
DE69714761D1 (de) 2002-09-19
PT941219E (pt) 2002-12-31
EA001385B1 (ru) 2001-02-26
ES2180943T3 (es) 2003-02-16
US6107497A (en) 2000-08-22
AU2139397A (en) 1997-09-16
CA2246541A1 (en) 1997-09-04
EP0941219B1 (de) 2002-08-14
WO1997031911A1 (en) 1997-09-04
GEP20002270B (en) 2000-10-25
EA199801068A1 (ru) 2000-06-26
DE69714761T2 (de) 2003-01-02
AU723968B2 (en) 2000-09-07
JP2001526626A (ja) 2001-12-18
EP0941219A4 (de) 1999-10-27
EA001405B1 (ru) 2001-02-26
ATE222247T1 (de) 2002-08-15
CA2246541C (en) 2005-05-24
PL328578A1 (en) 1999-02-01

Similar Documents

Publication Publication Date Title
Sakaitani et al. Selective transformation of Nt-butoxycarbonyl group into n-alkoxy-carbonyl group via n-carboxylate ion equivalent
US5614645A (en) Methods for making 2-debenzoyl and -2-acyl taxol derivatives
DK0941219T3 (da) Mellemprodukt til anvendelse ved docetaxelsyntese og fremstillingsmetode derfor
Arenz et al. Synthesis and biochemical investigation of scyphostatin analogues as inhibitors of neutral sphingomyelinase
Shen et al. Synthesis of 1, 2, 3, 4‐Bisiminofullerene and 1, 2, 3, 4‐Bis (triazolino) fullerene—on the Mechanism of the Addition Reactions of Organic Azides to [60] Fullerene
Andrés et al. Stereoselective cyanation of chiral α-amino aldehydes by reaction with Nagata's reagent: a route to enantiopure β-amino-α-hydroxy acids
Benedek et al. Efficient Synthesis of Hydroxy‐Substituted Cispentacin Derivatives
Bhat et al. Utility of tetrathiomolybdate and tetraselenotungstate: efficient synthesis of cystine, selenocystine, and their higher homologues
BR9710234A (pt) Processo de acilação de 10-desacetilbacatina iii e itermediário para a produção de bacatina iii.
Guerrero et al. Oxidative radical cyclization on enamide systems using n-Bu3SnH and dilauroyl peroxide
Chen et al. Sc (OTf) 3-catalyzed three-component cascade reaction: One-pot synthesis of substituted 3-oxoisoindoline-1-carbonitrile derivatives
Aghapoor et al. The different, but interesting behaviors of benzyl systems in the Willgerodt-Kindler reaction under solvent-free conditions
Seki et al. 2-Thiazolidinone: a novel thiol protective surrogate of complete atom efficiency, a practical synthesis of (+)-biotin
Nemoto et al. Highly diastereoselective nucleophilic addition reactions of masked acyl cyanide reagents to tert-butanesulfiminides
Dietz et al. Asymmetric synthesis of all stereoisomers of α-methylthreonine using an organocatalytic Steglich rearrangement reaction as a key step
Abbiati et al. [2+ 2] Cycloaddition reactions of 1-benzyl-2, 4-diphenyl-1, 3-diazabuta-1, 3-diene with chiral ketenes
Akimura et al. Synthesis of Tetracyclic Molecules Containing Medium-Sized Heterocycles: Scope Expansion of Cascade Nicholas and Pauson–Khand Methodology
ATE223394T1 (de) Verahren zur selektiven acylierung von 10- deacetylbaccatin-iii in der c-10 position
de Meijere et al. Synthesis and biological activity of simplified belactosin C analogues
Stademann et al. NO3● Induced Self-Terminating Radical Oxygenations: Diastereoselective Synthesis of Anellated Pyrrolidines
Xu et al. An efficient and practical synthesis of mandelic acid by combination of complex phase transfer catalyst and ultrasonic irradiation
Szakonyi et al. Synthesis of 3‐and 4‐Hydroxy‐2‐aminocyclohexanecarboxylic Acids by Iodocyclization
Satheesh et al. Synthesis and characterization of impurities of Apixaban drug substance—An anticoagulant
Sharma et al. Oxa-Michael Addition Reactions of 3-hydroxy-2-azetidinones: Synthesis of 1, 3, 4-Trisubstituted-2-Azetidinones
Hillier et al. Synthesis of hydantoins and dihydrouracils via thermally-promoted cyclization of ureidoacetamides