DK0934261T3 - Fremgangsmåde til fremstilling af dithiobis-alkansulfonater og -phosphonater - Google Patents
Fremgangsmåde til fremstilling af dithiobis-alkansulfonater og -phosphonaterInfo
- Publication number
- DK0934261T3 DK0934261T3 DK97942102T DK97942102T DK0934261T3 DK 0934261 T3 DK0934261 T3 DK 0934261T3 DK 97942102 T DK97942102 T DK 97942102T DK 97942102 T DK97942102 T DK 97942102T DK 0934261 T3 DK0934261 T3 DK 0934261T3
- Authority
- DK
- Denmark
- Prior art keywords
- disulfides
- alkanesulfonates
- dithiobis
- phosphonates
- preparation
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical class OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 title 1
- 150000002019 disulfides Chemical class 0.000 abstract 3
- BWGNESOTFCXPMA-UHFFFAOYSA-N Dihydrogen disulfide Chemical compound SS BWGNESOTFCXPMA-UHFFFAOYSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- -1 alkenyl sulfonate salt Chemical class 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229940044683 chemotherapy drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000000116 mitigating effect Effects 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 150000003057 platinum Chemical class 0.000 abstract 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
- 229940126585 therapeutic drug Drugs 0.000 abstract 1
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/22—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
- C07C319/24—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides by reactions involving the formation of sulfur-to-sulfur bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/02—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
- C07C319/04—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols by addition of hydrogen sulfide or its salts to unsaturated compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/16—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by addition of hydrogen sulfide or its salts to unsaturated compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2821296P | 1996-10-01 | 1996-10-01 | |
| PCT/GB1997/002576 WO1998014426A1 (en) | 1996-10-01 | 1997-09-23 | Process for producing mercaptoalkanesulfonates and phosphonates and derivatives thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0934261T3 true DK0934261T3 (da) | 2001-11-19 |
Family
ID=21842177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97942102T DK0934261T3 (da) | 1996-10-01 | 1997-09-23 | Fremgangsmåde til fremstilling af dithiobis-alkansulfonater og -phosphonater |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US5808140A (da) |
| EP (1) | EP0934261B1 (da) |
| JP (1) | JP4104662B2 (da) |
| CN (1) | CN1082047C (da) |
| AT (1) | ATE207892T1 (da) |
| AU (1) | AU718575B2 (da) |
| CA (1) | CA2263204C (da) |
| DE (1) | DE69707911T2 (da) |
| DK (1) | DK0934261T3 (da) |
| ES (1) | ES2163197T3 (da) |
| PT (1) | PT934261E (da) |
| WO (1) | WO1998014426A1 (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6160167A (en) * | 1998-04-21 | 2000-12-12 | Bionumerik Pharmaceuticals, Inc. | Mercaptans and disulfides |
| US6031006A (en) * | 1999-10-21 | 2000-02-29 | Bionumerik Pharmaceuticals, Inc. | Method of treating diabetic nephropathy |
| FR2811987A1 (fr) * | 2000-07-18 | 2002-01-25 | Expansia Sa | Procede de preparation du 2,2'-dithiobis(ethanesulfonate) de disodium |
| US7572436B1 (en) | 2000-09-11 | 2009-08-11 | Therapro Technologies, Inc. | Thionin as an antineoplastic and immunostimulant |
| US7034054B2 (en) * | 2000-12-15 | 2006-04-25 | Galileo Pharmaceuticals, Inc. | Methods for the prevention and treatment of cerebral ischemia using non-alpha tocopherols |
| US8710095B2 (en) | 2002-04-30 | 2014-04-29 | Bionumerik Pharmaceuticals, Inc. | Drugs for prophylaxis or mitigation of taxane-induced neurotoxicity |
| US6504049B1 (en) * | 2002-04-30 | 2003-01-07 | Bionumerik Pharmaceuticals, Inc. | Process for synthesizing pharmaceutically active disulfide salts |
| US6765148B2 (en) | 2002-04-30 | 2004-07-20 | Illinois Tool Works Inc. | C-shaped grommet |
| EP1694637A4 (en) * | 2003-12-17 | 2007-09-26 | Bionumerik Pharmaceuticals Inc | PROCESS FOR SYNTHESIS OF DISULFIDENE |
| US20050256055A1 (en) * | 2004-05-12 | 2005-11-17 | Hausheer Frederick H | Compounds and methods for reducing undesired toxicity of chemotherapeutic agents |
| US7282602B2 (en) * | 2004-09-21 | 2007-10-16 | Bionumerik Pharmaceuticals, Inc. | Medicinal disulfide salts |
| US20060063742A1 (en) * | 2004-09-21 | 2006-03-23 | Hausheer Frederick H | Method of treatment for or protection against lymphedema |
| JP5109081B2 (ja) * | 2006-04-26 | 2012-12-26 | 東洋紡株式会社 | アルケンスルホン酸塩を用いたチオカルボアルキルアルカンスルホン酸塩、メルカプトアルカンスルホン酸塩およびジチオビス（アルカンスルホン酸）塩の製造方法 |
| DE602008005459D1 (de) * | 2007-08-03 | 2011-04-21 | Ucb Pharma Sa | Sulfanylderivate und ihre verwendung als synthetische zwischenprodukte |
| CN102014891B (zh) | 2008-03-14 | 2013-12-18 | 比奥纽默里克药物公司 | 增加癌症患者存活时间的化合物的组合物和使用方法 |
| US7924143B2 (en) * | 2008-06-09 | 2011-04-12 | Research In Motion Limited | System and method for providing tactile feedback to a user of an electronic device |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2517934A (en) * | 1946-11-18 | 1950-08-08 | Phillips Petroleum Co | Production of alkyl disulfide |
| BE617176A (da) * | 1960-10-28 | |||
| US3978137A (en) * | 1975-03-14 | 1976-08-31 | Universal Oil Products Company | Oxidation of sulfur-containing compounds |
| US3994979A (en) * | 1975-05-01 | 1976-11-30 | Phillips Petroleum Company | Disulfide process |
| US4670602A (en) * | 1980-08-12 | 1987-06-02 | Phillips Petroleum Co. | Method of making disulfides using a combination reaction vessel and aspirator-mixer |
| DE4127821A1 (de) * | 1991-08-23 | 1993-02-25 | Basf Ag | Disulfide, verfahren zu deren herstellung und deren verwendung |
-
1997
- 1997-09-23 DE DE69707911T patent/DE69707911T2/de not_active Expired - Lifetime
- 1997-09-23 CN CN97198276A patent/CN1082047C/zh not_active Expired - Lifetime
- 1997-09-23 ES ES97942102T patent/ES2163197T3/es not_active Expired - Lifetime
- 1997-09-23 WO PCT/GB1997/002576 patent/WO1998014426A1/en active IP Right Grant
- 1997-09-23 CA CA002263204A patent/CA2263204C/en not_active Expired - Fee Related
- 1997-09-23 PT PT97942102T patent/PT934261E/pt unknown
- 1997-09-23 DK DK97942102T patent/DK0934261T3/da active
- 1997-09-23 AT AT97942102T patent/ATE207892T1/de active
- 1997-09-23 AU AU43902/97A patent/AU718575B2/en not_active Ceased
- 1997-09-23 JP JP51630298A patent/JP4104662B2/ja not_active Expired - Lifetime
- 1997-09-23 EP EP97942102A patent/EP0934261B1/en not_active Expired - Lifetime
- 1997-09-24 US US08/935,463 patent/US5808140A/en not_active Expired - Lifetime
-
1998
- 1998-06-30 US US09/108,168 patent/US5922902A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CN1231658A (zh) | 1999-10-13 |
| EP0934261A1 (en) | 1999-08-11 |
| US5922902A (en) | 1999-07-13 |
| ATE207892T1 (de) | 2001-11-15 |
| ES2163197T3 (es) | 2002-01-16 |
| AU718575B2 (en) | 2000-04-13 |
| WO1998014426A1 (en) | 1998-04-09 |
| CA2263204A1 (en) | 1998-04-09 |
| DE69707911D1 (de) | 2001-12-06 |
| PT934261E (pt) | 2002-04-29 |
| US5808140A (en) | 1998-09-15 |
| JP4104662B2 (ja) | 2008-06-18 |
| DE69707911T2 (de) | 2002-04-04 |
| CN1082047C (zh) | 2002-04-03 |
| AU4390297A (en) | 1998-04-24 |
| CA2263204C (en) | 2005-06-07 |
| JP2001501219A (ja) | 2001-01-30 |
| EP0934261B1 (en) | 2001-10-31 |
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