DK0925373T3 - Fremgangsmåde til påvisning af nukleinsyrer ved fastlæggelse af massen - Google Patents

Fremgangsmåde til påvisning af nukleinsyrer ved fastlæggelse af massen

Info

Publication number
DK0925373T3
DK0925373T3 DK97938922T DK97938922T DK0925373T3 DK 0925373 T3 DK0925373 T3 DK 0925373T3 DK 97938922 T DK97938922 T DK 97938922T DK 97938922 T DK97938922 T DK 97938922T DK 0925373 T3 DK0925373 T3 DK 0925373T3
Authority
DK
Denmark
Prior art keywords
nucleic acid
mass
nucleic acids
determination
detecting nucleic
Prior art date
Application number
DK97938922T
Other languages
English (en)
Inventor
Frank Bergmann
Rupert Herrmann
Uwe Kobold
Original Assignee
Pna Diagnostics As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pna Diagnostics As filed Critical Pna Diagnostics As
Application granted granted Critical
Publication of DK0925373T3 publication Critical patent/DK0925373T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6872—Methods for sequencing involving mass spectrometry
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK97938922T 1996-08-20 1997-08-18 Fremgangsmåde til påvisning af nukleinsyrer ved fastlæggelse af massen DK0925373T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19633436A DE19633436A1 (de) 1996-08-20 1996-08-20 Verfahren zum Nachweis von Nukleinsäuren unter Ermittlung der Masse
PCT/EP1997/004494 WO1998007885A1 (de) 1996-08-20 1997-08-18 Verfahren zum nachweis von nukleinsäuren unter ermittlung der masse

Publications (1)

Publication Number Publication Date
DK0925373T3 true DK0925373T3 (da) 2003-12-08

Family

ID=7803052

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97938922T DK0925373T3 (da) 1996-08-20 1997-08-18 Fremgangsmåde til påvisning af nukleinsyrer ved fastlæggelse af massen

Country Status (9)

Country Link
US (1) US6235476B1 (da)
EP (1) EP0925373B1 (da)
JP (1) JP2001505045A (da)
AT (1) ATE252647T1 (da)
AU (1) AU732167B2 (da)
CA (1) CA2263847A1 (da)
DE (2) DE19633436A1 (da)
DK (1) DK0925373T3 (da)
WO (1) WO1998007885A1 (da)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7718354B2 (en) 2001-03-02 2010-05-18 Ibis Biosciences, Inc. Methods for rapid identification of pathogens in humans and animals
US20040121314A1 (en) * 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents in containers
US7666588B2 (en) 2001-03-02 2010-02-23 Ibis Biosciences, Inc. Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
US7226739B2 (en) 2001-03-02 2007-06-05 Isis Pharmaceuticals, Inc Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations
US20030027135A1 (en) 2001-03-02 2003-02-06 Ecker David J. Method for rapid detection and identification of bioagents
US20040121311A1 (en) 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents in livestock
US7217510B2 (en) 2001-06-26 2007-05-15 Isis Pharmaceuticals, Inc. Methods for providing bacterial bioagent characterizing information
US8073627B2 (en) 2001-06-26 2011-12-06 Ibis Biosciences, Inc. System for indentification of pathogens
JPWO2003027673A1 (ja) * 2001-07-31 2005-01-13 オリンパス株式会社 遺伝子検査装置およびそれを用いた標的核酸検出方法
DE10159904A1 (de) * 2001-12-06 2003-07-03 Adnagen Ag Oligonukleotidanordnung, Verfahren zum Nukleotidnachweis sowie Vorrichtung hierfür
CA2508726A1 (en) 2002-12-06 2004-07-22 Isis Pharmaceuticals, Inc. Methods for rapid identification of pathogens in humans and animals
US7648678B2 (en) 2002-12-20 2010-01-19 Dako Denmark A/S Method and system for pretreatment of tissue slides
US8046171B2 (en) * 2003-04-18 2011-10-25 Ibis Biosciences, Inc. Methods and apparatus for genetic evaluation
US8057993B2 (en) 2003-04-26 2011-11-15 Ibis Biosciences, Inc. Methods for identification of coronaviruses
US7964343B2 (en) 2003-05-13 2011-06-21 Ibis Biosciences, Inc. Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US8158354B2 (en) 2003-05-13 2012-04-17 Ibis Biosciences, Inc. Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US20100035239A1 (en) * 2003-09-11 2010-02-11 Isis Pharmaceuticals, Inc. Compositions for use in identification of bacteria
US8097416B2 (en) 2003-09-11 2012-01-17 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US20120122102A1 (en) 2003-09-11 2012-05-17 Rangarajan Sampath Compositions for use in identification of bacteria
US8546082B2 (en) 2003-09-11 2013-10-01 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US7666592B2 (en) * 2004-02-18 2010-02-23 Ibis Biosciences, Inc. Methods for concurrent identification and quantification of an unknown bioagent
US8119336B2 (en) * 2004-03-03 2012-02-21 Ibis Biosciences, Inc. Compositions for use in identification of alphaviruses
US7714275B2 (en) 2004-05-24 2010-05-11 Ibis Biosciences, Inc. Mass spectrometry with selective ion filtration by digital thresholding
US20050266411A1 (en) 2004-05-25 2005-12-01 Hofstadler Steven A Methods for rapid forensic analysis of mitochondrial DNA
US7811753B2 (en) 2004-07-14 2010-10-12 Ibis Biosciences, Inc. Methods for repairing degraded DNA
WO2006135400A2 (en) 2004-08-24 2006-12-21 Isis Pharmaceuticals, Inc. Methods for rapid identification of recombinant organisms
EP1869180B1 (en) 2005-03-03 2013-02-20 Ibis Biosciences, Inc. Compositions for use in identification of polyoma viruses
US8084207B2 (en) 2005-03-03 2011-12-27 Ibis Bioscience, Inc. Compositions for use in identification of papillomavirus
US20090305237A1 (en) * 2005-05-26 2009-12-10 Trustees Of Boston University Quantification of nucleic acids and proteins using oligonucleotide mass tags
JP2009502137A (ja) 2005-07-21 2009-01-29 アイシス ファーマシューティカルズ インコーポレイティッド 核酸変種の迅速な同定および定量のための方法
US9149473B2 (en) 2006-09-14 2015-10-06 Ibis Biosciences, Inc. Targeted whole genome amplification method for identification of pathogens
WO2008104002A2 (en) 2007-02-23 2008-08-28 Ibis Biosciences, Inc. Methods for rapid forensic dna analysis
US9598724B2 (en) 2007-06-01 2017-03-21 Ibis Biosciences, Inc. Methods and compositions for multiple displacement amplification of nucleic acids
WO2010033627A2 (en) 2008-09-16 2010-03-25 Ibis Biosciences, Inc. Sample processing units, systems, and related methods
US8550694B2 (en) 2008-09-16 2013-10-08 Ibis Biosciences, Inc. Mixing cartridges, mixing stations, and related kits, systems, and methods
WO2010033625A1 (en) 2008-09-16 2010-03-25 Ibis Biosciences, Inc. Microplate handling systems and related computer program products and methods
EP2396803A4 (en) 2009-02-12 2016-10-26 Ibis Biosciences Inc IONIZATION PROBE ASSEMBLIES
WO2011008972A1 (en) 2009-07-17 2011-01-20 Ibis Biosciences, Inc. Systems for bioagent identification
US8950604B2 (en) 2009-07-17 2015-02-10 Ibis Biosciences, Inc. Lift and mount apparatus
ES2628739T3 (es) 2009-10-15 2017-08-03 Ibis Biosciences, Inc. Amplificación por desplazamiento múltiple
JP6841609B2 (ja) 2015-07-10 2021-03-10 ３スキャン インコーポレイテッド 組織学的染色の空間的多重化
EP4095254A3 (en) * 2021-05-27 2022-12-14 New England Biolabs, Inc. Fragmentation of dna

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288644A (en) 1990-04-04 1994-02-22 The Rockefeller University Instrument and method for the sequencing of genome
US5605798A (en) * 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
GB2285445A (en) 1993-12-06 1995-07-12 Pna Diagnostics As Protecting nucleic acids and methods of analysis
US5780232A (en) * 1996-05-28 1998-07-14 Atom Sciences, Inc. DNA sequencing, mapping, and diagnostic processes using hybridization and stable isotope labels of DNA

Also Published As

Publication number Publication date
JP2001505045A (ja) 2001-04-17
EP0925373B1 (de) 2003-10-22
DE59710900D1 (de) 2003-11-27
AU732167B2 (en) 2001-04-12
CA2263847A1 (en) 1998-02-26
ATE252647T1 (de) 2003-11-15
EP0925373A1 (de) 1999-06-30
AU4119497A (en) 1998-03-06
DE19633436A1 (de) 1998-02-26
WO1998007885A1 (de) 1998-02-26
US6235476B1 (en) 2001-05-22

Similar Documents

Publication Publication Date Title
DK0925373T3 (da) Fremgangsmåde til påvisning af nukleinsyrer ved fastlæggelse af massen
DK463089A (da) Fremgangsmaade og reagenssaet til detektion af en specifik nucleinsyresekvens i en proeve indeholdende en nucleinsyre
HUP9901321A2 (hu) Eljárások és készítmények nukleinsav-molekulák szekvenciájának maghatározására
GB8827160D0 (en) Detection & quantitative determination of rna & dna
DE69820111D1 (de) Massenspektroskopische verfahren zur sequenzierung von nukleinsäuren
DE68918657T2 (de) Verfahren zum Nachweis spezifischer Nukleinsäuresequenzen.
DE69033850D1 (de) Nukleinsäuresonden zum Nachweis von HPV-Transkripts
DE60041355D1 (de) Verfahren zur detektion von erkrankungen
DE69619247D1 (de) Verfahren zur sequenzierung von nukleinsäuren
DE69520330D1 (de) Verfahren zum Nachweis von spezifischen Nukleinsäuresequenzen
ATE230801T1 (de) Verfahren zur detektion von zielnukleinsäure, verfahren zu ihrer quantifizierung und pyrylium- verbindungen zur chemilumineszenz-analyse
ATE125947T1 (de) Bestimmungsmethode unter verwendung von polynucleotidsequenzen.
DE68915202T2 (de) Verfahren zur Vermehrung und zum Nachweis von Nukleinsäuresequenzen.
ATE224458T1 (de) Techniken zu detektion von fehlpaarungen
ES539560A0 (es) Perfeccionamientos en las disposiciones para la deteccion desecuencias determinadas de nucleotidos, procedimiento de deteccion y de caracterizacion de una secuencia o de un fragmento de acido nucleico determinado y sonda clonad
DE69003104T2 (de) Verfahren zum nachweis von spezifischen sequenzen von nukleinsäuren und ihre verwendungen.
DK0407789T3 (da) Fremgangsmåde til detektering af nukleinsyrer
WO1999055913A3 (en) Reduced complexity nucleic acid targets and methods of using same
AU4663997A (en) Detection and identification of non-polio enteroviruses
DE69717001D1 (de) Verfahren zur Bestimmung des Endpunktes von enzymatischen Nachweisverfahren
DE69907667D1 (de) Verfahren zur frühzeitigen erkennung von reaktorverschmutzung bei der gasphasenpolymerisation
ATE269417T1 (de) Verfahren zur erkennung und messung von gespleisten nukleinsäuren
WO1999007886A3 (de) Nucleinsäuremolekül-satz für salmonella-nachweis, nucleinsäuren, kit und verwendung
NO880010D0 (no) Analytisk metode for detektering og maaling av spesifikke nuklein syresekvenser.
MX9709074A (es) Metodo para reducir los inhibidores de hibridizacion del acido nucleico.