DK0925364T3 - Et regulerbart ekspressionssystem til brug i mælkesyrebakterier - Google Patents

Et regulerbart ekspressionssystem til brug i mælkesyrebakterier

Info

Publication number
DK0925364T3
DK0925364T3 DK97936612T DK97936612T DK0925364T3 DK 0925364 T3 DK0925364 T3 DK 0925364T3 DK 97936612 T DK97936612 T DK 97936612T DK 97936612 T DK97936612 T DK 97936612T DK 0925364 T3 DK0925364 T3 DK 0925364T3
Authority
DK
Denmark
Prior art keywords
pct
sequence
lactic acid
orientation
gene
Prior art date
Application number
DK97936612T
Other languages
English (en)
Inventor
Soeren Michael Madsen
Astrid Vrang
Jose Arnau
Peter Ravn
Johnsen Mads Groenvald
Hans Israelsen
Original Assignee
Bioteknologisk Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioteknologisk Inst filed Critical Bioteknologisk Inst
Application granted granted Critical
Publication of DK0925364T3 publication Critical patent/DK0925364T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fodder In General (AREA)
DK97936612T 1996-09-06 1997-08-22 Et regulerbart ekspressionssystem til brug i mælkesyrebakterier DK0925364T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71143496A 1996-09-06 1996-09-06
PCT/DK1997/000341 WO1998010079A1 (en) 1996-09-06 1997-08-22 A lactic acid bacterial regulatable expression system

Publications (1)

Publication Number Publication Date
DK0925364T3 true DK0925364T3 (da) 2003-02-24

Family

ID=24858080

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97936612T DK0925364T3 (da) 1996-09-06 1997-08-22 Et regulerbart ekspressionssystem til brug i mælkesyrebakterier

Country Status (10)

Country Link
US (1) US6133023A (da)
EP (1) EP0925364B1 (da)
AT (1) ATE226637T1 (da)
CA (1) CA2264495C (da)
DE (1) DE69716622T2 (da)
DK (1) DK0925364T3 (da)
ES (1) ES2185972T3 (da)
NZ (1) NZ334521A (da)
PT (1) PT925364E (da)
WO (1) WO1998010079A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6436694B1 (en) 1998-01-09 2002-08-20 Cubist Pharmaceuticals, Inc. Regulable gene expression in gram-positive bacteria
DE60033037T2 (de) 1999-08-06 2007-07-19 Bioneer A/S Signalpeptide aus lactococcus lactis
US7009042B1 (en) * 1999-10-07 2006-03-07 Corixa Corporation Methods of using a Mycobacterium tuberculosis coding sequence to facilitate stable and high yield expression of the heterologous proteins
AU779846B2 (en) * 1999-10-07 2005-02-17 Corixa Corporation Methods of using a mycobacterium tuberculosis coding sequence to facilitate stable and high yield expression of heterologous proteins
DK1248536T3 (da) * 2000-01-21 2007-02-26 Hansens Lab Porphyrinholdige mælkesyrebakterieceller og anvendelse deraf
AU2002210402A1 (en) * 2000-10-20 2002-04-29 Bioteknologisk Institut Regulation of promoter activity using a polypeptide isolated from lactococcus lactis
AU2002210401B2 (en) * 2000-10-20 2006-07-20 Bioneer A/S Fermentation method for production of heterologous gene products in lactic acid bacteria
EP1239032A1 (en) * 2001-03-02 2002-09-11 Société des Produits Nestlé S.A. Lactic acid bacteria as agents for treating and preventing allergy
KR20020090546A (ko) * 2001-05-28 2002-12-05 주식회사 알엔에이 유산균 염색체 ｄｎａ로의 삽입을 위한 삽입 벡터
CA2619943A1 (en) * 2005-08-26 2007-03-01 Cerenis Therapeutics Holding Sa Compositions and methods for producing apolipoprotein gene products in lactic acid bacteria
NZ766918A (en) 2012-01-12 2023-03-31 Auxilium Int Holdings Inc Clostridium histolyticum enzymes and methods for the use thereof
SG10201901828TA (en) * 2019-02-28 2020-09-29 Nat Univ Singapore Recombinant bacteria and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7232087A (en) * 1986-03-26 1987-10-20 Genexpress Aps Biological containment
GB9006400D0 (en) * 1990-03-22 1990-05-23 Ciba Geigy Ag Bacterial vectors
WO1992004451A1 (en) * 1990-08-30 1992-03-19 Genesit Oy Promoter probe vectors, able to replicate in e.coli, b.subtilis, lactococci and lactobacillus as well as uses thereof
ES2235159T5 (es) * 1992-12-30 2010-05-11 Bioneer A/S Bacteria lactico recombinante que contiene un promotor insertado.
US5837509A (en) * 1992-12-30 1998-11-17 Bioteknologisk Institut Recombinant lactic acid bacterium containing an inserted promoter and method of constructing same
WO1995031563A1 (en) * 1994-05-12 1995-11-23 Quest International B.V. Complex inducible promoter system derivable from a phage of a lactic acid bacterium (lab), and its use in a lab for production of a desired protein
DE69527126T2 (de) * 1994-11-18 2002-12-12 Stichting Nederlands Instituut Voor Zuivelonderzoek, Ede Verfahren zur Kontrolle der Genexpression in Milchsäurebakterien

Also Published As

Publication number Publication date
PT925364E (pt) 2003-03-31
ATE226637T1 (de) 2002-11-15
NZ334521A (en) 2000-03-27
ES2185972T3 (es) 2003-05-01
DE69716622D1 (de) 2002-11-28
EP0925364B1 (en) 2002-10-23
WO1998010079A1 (en) 1998-03-12
DE69716622T2 (de) 2003-07-10
CA2264495A1 (en) 1998-03-12
US6133023A (en) 2000-10-17
CA2264495C (en) 2007-04-17
EP0925364A1 (en) 1999-06-30

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