DK0925290T3 - Fremgangsmåde til selektiv alkylering af epoxy-alkoholer - Google Patents

Fremgangsmåde til selektiv alkylering af epoxy-alkoholer

Info

Publication number
DK0925290T3
DK0925290T3 DK97930006T DK97930006T DK0925290T3 DK 0925290 T3 DK0925290 T3 DK 0925290T3 DK 97930006 T DK97930006 T DK 97930006T DK 97930006 T DK97930006 T DK 97930006T DK 0925290 T3 DK0925290 T3 DK 0925290T3
Authority
DK
Denmark
Prior art keywords
selective alkylation
epoxy alcohols
alcohols
epoxy
alkylation
Prior art date
Application number
DK97930006T
Other languages
English (en)
Inventor
Xiu C Wang
Luping Liu
Ashok V Bhatia
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK0925290T3 publication Critical patent/DK0925290T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D301/00Preparation of oxiranes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/04Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reaction of ammonia or amines with olefin oxides or halohydrins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
DK97930006T 1996-06-19 1997-06-18 Fremgangsmåde til selektiv alkylering af epoxy-alkoholer DK0925290T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/667,038 US5942633A (en) 1996-06-19 1996-06-19 Process for the selective alkylation of betaxolol intermediates
PCT/US1997/010337 WO1997048690A1 (en) 1996-06-19 1997-06-18 Process for the selective alkylation of epoxy-alcohols

Publications (1)

Publication Number Publication Date
DK0925290T3 true DK0925290T3 (da) 2004-03-29

Family

ID=24676556

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97930006T DK0925290T3 (da) 1996-06-19 1997-06-18 Fremgangsmåde til selektiv alkylering af epoxy-alkoholer

Country Status (9)

Country Link
US (1) US5942633A (da)
EP (1) EP0925290B1 (da)
JP (1) JP2000512999A (da)
AT (1) ATE254610T1 (da)
DE (1) DE69726293T2 (da)
DK (1) DK0925290T3 (da)
ES (1) ES2212113T3 (da)
PT (1) PT925290E (da)
WO (1) WO1997048690A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7019172B2 (en) * 2004-06-30 2006-03-28 Council Of Scientific And Industrial Research Process for preparation of S-(-)-betaxolol and salts thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3541130A (en) * 1967-02-06 1970-11-17 Boehringer Sohn Ingelheim 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes
GB1285038A (en) * 1969-02-21 1972-08-09 Ici Ltd Alkanolamine derivatives
US4018778A (en) * 1972-05-24 1977-04-19 Cassella Farbwerke Mainkur Aktiengesellschaft Derivatives of 1-phenoxy-3-amino-propane-2-ol and process for their production
FR2330383A1 (fr) * 1975-11-06 1977-06-03 Synthelabo Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment
CA1265523A (en) * 1984-08-21 1990-02-06 Stephen Vigmond Preparation of phenol ethers using cyclic intermediates
ES8609190A1 (es) * 1985-02-07 1986-07-16 Pharma Investi S A Un procedimiento para preparar eteres fenolicos
SE8801518D0 (sv) * 1988-04-22 1988-04-22 Astra Pharma Prod A novel process
US5208352A (en) * 1992-04-02 1993-05-04 Sandoz Ltd. Process for preparing the R- and S-isomers of 2-hydroxy-methyl-2-octadecyloxymethyl-tetrahydrofuran and their use in preparing stereoisomers of pharmacologically active compounds

Also Published As

Publication number Publication date
EP0925290A1 (en) 1999-06-30
JP2000512999A (ja) 2000-10-03
ATE254610T1 (de) 2003-12-15
US5942633A (en) 1999-08-24
WO1997048690A1 (en) 1997-12-24
DE69726293D1 (de) 2003-12-24
PT925290E (pt) 2004-04-30
ES2212113T3 (es) 2004-07-16
DE69726293T2 (de) 2004-09-23
EP0925290B1 (en) 2003-11-19

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