DK0914043T3 - Implanterbare agarose-kollagen-korn, som indeholder celler, der dannet et diffunderbart produkt, og anvendelser heraf - Google Patents

Implanterbare agarose-kollagen-korn, som indeholder celler, der dannet et diffunderbart produkt, og anvendelser heraf

Info

Publication number
DK0914043T3
DK0914043T3 DK97915180T DK97915180T DK0914043T3 DK 0914043 T3 DK0914043 T3 DK 0914043T3 DK 97915180 T DK97915180 T DK 97915180T DK 97915180 T DK97915180 T DK 97915180T DK 0914043 T3 DK0914043 T3 DK 0914043T3
Authority
DK
Denmark
Prior art keywords
containing cells
grains containing
agarose
diffusible product
implantable
Prior art date
Application number
DK97915180T
Other languages
Danish (da)
English (en)
Inventor
Kanti Jain
Albert L Rubin
Shirin Asina
Barry Smith
Kurt Stenzel
Original Assignee
Rogosin Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/745,063 external-priority patent/US5888497A/en
Application filed by Rogosin Inst filed Critical Rogosin Inst
Application granted granted Critical
Publication of DK0914043T3 publication Critical patent/DK0914043T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/22Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0693Tumour cells; Cancer cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/126Immunoprotecting barriers, e.g. jackets, diffusion chambers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Developmental Biology & Embryology (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
DK97915180T 1996-04-03 1997-03-21 Implanterbare agarose-kollagen-korn, som indeholder celler, der dannet et diffunderbart produkt, og anvendelser heraf DK0914043T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62559596A 1996-04-03 1996-04-03
US08/745,063 US5888497A (en) 1996-04-03 1996-11-07 Agarose coated agarose beads containing cancer cells that produce material which suppresses cancer cell proliferation
PCT/US1997/004548 WO1997036495A1 (en) 1996-04-03 1997-03-21 Implantable agarose-collagen beads containing cells which produce a diffusible biological product, and uses thereof

Publications (1)

Publication Number Publication Date
DK0914043T3 true DK0914043T3 (da) 2004-02-09

Family

ID=27089961

Family Applications (2)

Application Number Title Priority Date Filing Date
DK03018701T DK1382346T3 (da) 1996-04-03 1997-03-21 Konditioneret medium og diffunderbare biologiske produkter fremstillet ved inkubering af indesluttede celler
DK97915180T DK0914043T3 (da) 1996-04-03 1997-03-21 Implanterbare agarose-kollagen-korn, som indeholder celler, der dannet et diffunderbart produkt, og anvendelser heraf

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK03018701T DK1382346T3 (da) 1996-04-03 1997-03-21 Konditioneret medium og diffunderbare biologiske produkter fremstillet ved inkubering af indesluttede celler

Country Status (16)

Country Link
EP (2) EP1382346B1 (de)
JP (2) JP3765039B2 (de)
CN (2) CN1119080C (de)
AT (2) ATE250858T1 (de)
AU (1) AU722109C (de)
CA (1) CA2250880C (de)
DE (2) DE69725317T2 (de)
DK (2) DK1382346T3 (de)
ES (2) ES2290390T3 (de)
FI (1) FI120332B (de)
HK (2) HK1019037A1 (de)
IL (1) IL126442A0 (de)
NO (1) NO320334B1 (de)
NZ (2) NZ331960A (de)
PT (1) PT914043E (de)
WO (1) WO1997036495A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6224912B1 (en) * 1996-04-03 2001-05-01 The Rogo Institute Cancer-cell proliferation-suppressing material produced by cancer cells restricted by entrapment
US6303151B1 (en) * 1996-04-03 2001-10-16 The Rogosin Institute Cancer-cell proliferation-suppressing material produced by cancer cells restricted by entrapment
US7297331B2 (en) 1996-04-03 2007-11-20 The Rogosin Institute Beads containing restricted cancer cells producing material suppressing cancer cell proliferation
NO983911D0 (no) 1998-08-26 1998-08-26 Norsk Hydro As Alginatkapsler til bruk ved behandling av hjernesvulst
AU2003264652B2 (en) * 1998-11-09 2006-09-14 The Rogosin Institute Compositions of restricted cells capable of rapid growth which produce proliferation suppressive materials, and uses thereof
US8257715B1 (en) 2004-08-26 2012-09-04 University Of Notre Dame Tissue vaccines and uses thereof
US8778360B2 (en) * 2005-10-27 2014-07-15 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US8778362B2 (en) 2005-10-27 2014-07-15 University Of Notre Dame Anti-tumor/cancer heterologous acellular collagenous preparations and uses thereof
US8802113B2 (en) 2005-10-27 2014-08-12 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US9308252B2 (en) 2005-10-27 2016-04-12 Cook Biotech, Inc. Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins
US9283266B2 (en) 2008-02-28 2016-03-15 University Of Notre Dame Metastasis inhibition preparations and methods
US8846059B2 (en) 2009-12-08 2014-09-30 University Of Notre Dame Extracellular matrix adjuvant and methods for prevention and/or inhibition of ovarian tumors and ovarian cancer
NZ624195A (en) * 2012-01-31 2015-07-31 Rogosin Inst Improved method for manufacture of macrobeads
US12038432B2 (en) 2018-02-02 2024-07-16 Wake Forest University Health Sciences Organoids related to immunotherapy and methods of preparing and using the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE441009B (sv) * 1982-03-08 1985-09-02 Kjell Nilsson Sett att immobilisera levande biomaterial i perlformiga polymerer
US4798786A (en) * 1982-05-06 1989-01-17 Stolle Research And Development Corporation Living cells encapsulated in crosslinked protein
CA1196862A (en) * 1983-06-01 1985-11-19 Anthony M.F. Sun Microencapsulation of living tissue and cells
US4663286A (en) * 1984-02-13 1987-05-05 Damon Biotech, Inc. Encapsulation of materials
SE8604684L (sv) * 1986-11-03 1988-05-04 Excorim Kommanditbolag Sett att belegga fasta partiklar med en hydrofil gel samt genom settet belagda partiklar
JP2691557B2 (ja) * 1988-04-15 1997-12-17 興研株式会社 人の悪性腫瘍細胞増殖抑制剤
US5053332A (en) * 1989-07-24 1991-10-01 Cook Richard B Agarose beads, preferably incorporating biological materials
US5241051A (en) * 1992-04-24 1993-08-31 Research Development Foundation Oncoinhibin
RU2177503C2 (ru) * 1994-01-13 2001-12-27 Рогозин Институт Макрогранула с секреторными клетками, способ ее получения и способ лечения заболеваний, вызванных нарушением функционирования секреторных клеток
US5651980A (en) * 1994-04-15 1997-07-29 Biohybrid Technologies, Inc. Methods of use of uncoated gel particles

Also Published As

Publication number Publication date
CA2250880C (en) 2008-01-15
NO984627L (no) 1998-11-30
HK1066026A1 (en) 2005-03-11
CN1296477C (zh) 2007-01-24
CN1215309A (zh) 1999-04-28
NZ337109A (en) 2004-12-24
DE69738170T2 (de) 2008-01-24
EP0914043B1 (de) 2003-10-01
AU2218897A (en) 1997-10-22
CN1119080C (zh) 2003-08-27
DE69725317T2 (de) 2004-07-29
ES2290390T3 (es) 2008-02-16
DE69725317D1 (de) 2003-11-06
JP2005104987A (ja) 2005-04-21
ATE250858T1 (de) 2003-10-15
EP1382346B1 (de) 2007-09-26
ES2206696T3 (es) 2004-05-16
CN1495253A (zh) 2004-05-12
DE69738170D1 (de) 2007-11-08
FI981957A0 (fi) 1998-09-11
NZ331960A (en) 1999-10-28
CA2250880A1 (en) 1997-10-09
PT914043E (pt) 2004-02-27
NO320334B1 (no) 2005-11-21
DK1382346T3 (da) 2008-01-28
JP3765039B2 (ja) 2006-04-12
JP4480152B2 (ja) 2010-06-16
FI981957A (fi) 1998-12-02
AU722109B2 (en) 2000-07-20
FI120332B (fi) 2009-09-30
WO1997036495A1 (en) 1997-10-09
HK1019037A1 (en) 2000-01-21
IL126442A0 (en) 1999-08-17
AU722109C (en) 2001-07-19
EP1382346A1 (de) 2004-01-21
EP0914043A4 (de) 2001-08-29
ATE374034T1 (de) 2007-10-15
JP2001503380A (ja) 2001-03-13
EP0914043A1 (de) 1999-05-12
NO984627D0 (no) 1998-10-02

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