DK0900569T3 - Terapeutisk middel til behandling af herniaramt intervertebral diskus - Google Patents
Terapeutisk middel til behandling af herniaramt intervertebral diskusInfo
- Publication number
- DK0900569T3 DK0900569T3 DK98306691T DK98306691T DK0900569T3 DK 0900569 T3 DK0900569 T3 DK 0900569T3 DK 98306691 T DK98306691 T DK 98306691T DK 98306691 T DK98306691 T DK 98306691T DK 0900569 T3 DK0900569 T3 DK 0900569T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- intervertebral disc
- herniaric
- therapeutic agent
- epidurally
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
- 102000037716 Chondroitin-sulfate-ABC endolyases Human genes 0.000 abstract 1
- 108090000819 Chondroitin-sulfate-ABC endolyases Proteins 0.000 abstract 1
- 102000011413 Chondroitinases and Chondroitin Lyases Human genes 0.000 abstract 1
- 108010023736 Chondroitinases and Chondroitin Lyases Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 229920002683 Glycosaminoglycan Polymers 0.000 abstract 1
- 230000000593 degrading effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/51—Lyases (4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22687297 | 1997-08-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0900569T3 true DK0900569T3 (da) | 2003-01-27 |
Family
ID=16851905
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98306691T DK0900569T3 (da) | 1997-08-22 | 1998-08-20 | Terapeutisk middel til behandling af herniaramt intervertebral diskus |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6063378A (de) |
| EP (1) | EP0900569B1 (de) |
| AT (1) | ATE225184T1 (de) |
| AU (1) | AU735216B2 (de) |
| CA (1) | CA2246033C (de) |
| DE (1) | DE69808402T2 (de) |
| DK (1) | DK0900569T3 (de) |
| ES (1) | ES2185117T3 (de) |
| RU (1) | RU2209080C2 (de) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU770725B2 (en) * | 1998-10-06 | 2004-02-26 | Howard An | Method of chemonucleolysis |
| US6783546B2 (en) | 1999-09-13 | 2004-08-31 | Keraplast Technologies, Ltd. | Implantable prosthetic or tissue expanding device |
| US6371984B1 (en) * | 1999-09-13 | 2002-04-16 | Keraplast Technologies, Ltd. | Implantable prosthetic or tissue expanding device |
| US6592625B2 (en) | 1999-10-20 | 2003-07-15 | Anulex Technologies, Inc. | Spinal disc annulus reconstruction method and spinal disc annulus stent |
| US8632590B2 (en) | 1999-10-20 | 2014-01-21 | Anulex Technologies, Inc. | Apparatus and methods for the treatment of the intervertebral disc |
| US7052516B2 (en) | 1999-10-20 | 2006-05-30 | Anulex Technologies, Inc. | Spinal disc annulus reconstruction method and deformable spinal disc annulus stent |
| US7935147B2 (en) | 1999-10-20 | 2011-05-03 | Anulex Technologies, Inc. | Method and apparatus for enhanced delivery of treatment device to the intervertebral disc annulus |
| US7951201B2 (en) | 1999-10-20 | 2011-05-31 | Anulex Technologies, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
| US8128698B2 (en) | 1999-10-20 | 2012-03-06 | Anulex Technologies, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
| US7615076B2 (en) | 1999-10-20 | 2009-11-10 | Anulex Technologies, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
| US7004970B2 (en) | 1999-10-20 | 2006-02-28 | Anulex Technologies, Inc. | Methods and devices for spinal disc annulus reconstruction and repair |
| US6805695B2 (en) | 2000-04-04 | 2004-10-19 | Spinalabs, Llc | Devices and methods for annular repair of intervertebral discs |
| US20030069639A1 (en) * | 2001-04-14 | 2003-04-10 | Tom Sander | Methods and compositions for repair or replacement of joints and soft tissues |
| WO2003037166A2 (en) * | 2001-11-01 | 2003-05-08 | Boyd Lawrence M | Devices and methods for the restoration of a spinal disc |
| WO2003037165A2 (en) * | 2001-11-01 | 2003-05-08 | Boyd Lawrence M | System and method for the pretreatment of the endplates of an intervertebral disc |
| EP1575548B1 (de) | 2002-05-04 | 2011-03-09 | Acorda Therapeutics, Inc. | Zusammensetzungen und verfahren zur förderung des neuronalen wachstums |
| WO2003102160A2 (en) * | 2002-06-03 | 2003-12-11 | Massachusetts Institute Of Technology | Rationally designed polysaccharide lyases derived from chondroitinase b |
| US7163545B2 (en) * | 2002-07-29 | 2007-01-16 | Mayo Foundation For Medical Education And Research | Spinal cord surgical implant |
| DE60337009D1 (de) * | 2002-08-15 | 2011-06-16 | Acorda Therapeutics Inc | Chimärisches protein |
| US20070134227A1 (en) * | 2003-03-31 | 2007-06-14 | Seikagaku Corporation | Catalyst for cleaving sugar chain |
| AU2004241088B2 (en) * | 2003-05-16 | 2010-08-05 | Acorda Therapeutics, Inc. | Compositions and methods for the treatment of CNS injuries |
| ES2887949T3 (es) | 2003-05-16 | 2021-12-29 | Acorda Therapeutics Inc | Mutantes degradantes de proteoglicanos para el tratamiento del SNC |
| US7959914B2 (en) | 2003-05-16 | 2011-06-14 | Acorda Therapeutics, Inc. | Methods of reducing extravasation of inflammatory cells |
| US7169405B2 (en) * | 2003-08-06 | 2007-01-30 | Warsaw Orthopedic, Inc. | Methods and devices for the treatment of intervertebral discs |
| EP1729672A2 (de) * | 2004-01-08 | 2006-12-13 | Spine Wave, Inc. | Vorrichtung und verfahren zum injizieren von fliessendem material an einer auseinandergezogenen gewebestelle |
| EP1750757B1 (de) * | 2004-05-18 | 2013-03-13 | Acorda Therapeutics, Inc. | Verfahren zur reinigung von chondroitinase und stabile formulierungen daraus |
| EP1768617A4 (de) * | 2004-06-29 | 2011-08-10 | Spine Wave Inc | Verfahren zur behandlung von defekten und verletzungen der bandscheibe |
| US9968120B2 (en) * | 2006-05-17 | 2018-05-15 | Dsm Nutritional Products Ag | Homogenized formulations containing microcapsules and methods of making and using thereof |
| EP1928490B8 (de) | 2005-09-26 | 2012-10-03 | Acorda Therapeutics, Inc. | Zusammensetzungen und verfahren zur verwendung von chondroitinase-abci-mutanten |
| US8642060B2 (en) * | 2006-04-24 | 2014-02-04 | Warsaw Orthopedic, Inc. | Controlled release systems and methods for osteal growth |
| US7879027B2 (en) * | 2006-04-24 | 2011-02-01 | Warsaw Orthopedic, Inc. | Controlled release devices for fusion of osteal structures |
| US8642059B2 (en) | 2006-04-24 | 2014-02-04 | Warsaw Orthopedic, Inc. | Controlled release systems and methods for intervertebral discs |
| US7771414B2 (en) * | 2006-04-24 | 2010-08-10 | Warsaw Orthopedic, Inc. | Controlled release devices for therapeutic treatments of spinal discs |
| EP2450442B1 (de) | 2006-10-10 | 2017-07-19 | Acorda Therapeutics, Inc. | Zusammensetzungen und verfahren zur verwendung von chondroitinase-abci-mutanten |
| US8163022B2 (en) | 2008-10-14 | 2012-04-24 | Anulex Technologies, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
| US8460319B2 (en) | 2010-01-11 | 2013-06-11 | Anulex Technologies, Inc. | Intervertebral disc annulus repair system and method |
| KR20140005842A (ko) | 2010-06-25 | 2014-01-15 | 샤이어 휴먼 지네틱 테라피즈 인크. | 헤파란 n-설파타제의 cns 전달을 위한 방법들 및 조성물들 |
| UA115648C2 (uk) | 2010-06-25 | 2017-12-11 | Шае Хюмен Дженетік Терапіс, Інк. | Доставка терапевтичних агентів до цнс |
| RU2660348C2 (ru) * | 2010-06-25 | 2018-07-05 | Шир Хьюман Дженетик Терапис, Инк. | Способы и композиции для доставки в цнс идуронат-2-сульфатазы |
| KR102537084B1 (ko) | 2010-06-25 | 2023-05-26 | 샤이어 휴먼 지네틱 테라피즈 인크. | 아릴설파타제 a의 cns 전달을 위한 방법들 및 조성물들 |
| SI3626258T1 (sl) | 2010-06-25 | 2021-11-30 | Shire Human Genetic Therapies, Inc. | Postopki in sestavki za dovajanje idunorat-2-sulfataze v cžs |
| TWI488641B (zh) * | 2010-12-13 | 2015-06-21 | 生化學工業股份有限公司 | 椎間盤突出治療劑 |
| EP2793922B1 (de) | 2011-12-23 | 2019-10-30 | Shire Human Genetic Therapies, Inc. | Stabile formulierungen zur verabreichung von arylsulfatase a in das zns |
| EP2948068A4 (de) | 2013-01-28 | 2016-09-28 | Cartiva Inc | Systeme und verfahren für orthopädischen reparaturen |
| US9737294B2 (en) | 2013-01-28 | 2017-08-22 | Cartiva, Inc. | Method and system for orthopedic repair |
| HUE046209T2 (hu) * | 2014-03-20 | 2020-02-28 | Stayble Therapeutics Ab | Kompozíció porckoronggal összefüggõ fájdalom kezelésében történõ alkalmazásra |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4696816A (en) * | 1985-11-07 | 1987-09-29 | Brown Mark D | Method for treating intervertebral disc displacement with enzymes |
| RU2021812C1 (ru) * | 1992-04-13 | 1994-10-30 | Всесоюзный научно-исследовательский институт технологии кровезаменителей и гормональных препаратов | Средство для лечения артрологических заболеваний |
| US5496718A (en) * | 1992-06-26 | 1996-03-05 | Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) | Chondroitinase ABC isolated from proteus vulgaris ATCC 6896 |
| JP3419811B2 (ja) * | 1993-02-24 | 2003-06-23 | マルハ株式会社 | コンドロイチナーゼ遺伝子 |
| US6228998B1 (en) * | 1994-07-22 | 2001-05-08 | Seikagaku Kogyo Kabushiki Kaisha | Amino spacered glycosaminoglycan derivatives and their use in copolymerization with acrylamide |
| DE69829605T2 (de) * | 1997-05-02 | 2006-02-09 | Seikagaku Corp. | Chondroitinase enthaltende Zusammensetzungen |
-
1998
- 1998-08-20 EP EP98306691A patent/EP0900569B1/de not_active Expired - Lifetime
- 1998-08-20 AT AT98306691T patent/ATE225184T1/de active
- 1998-08-20 DK DK98306691T patent/DK0900569T3/da active
- 1998-08-20 AU AU80826/98A patent/AU735216B2/en not_active Ceased
- 1998-08-20 US US09/137,197 patent/US6063378A/en not_active Expired - Lifetime
- 1998-08-20 DE DE69808402T patent/DE69808402T2/de not_active Expired - Lifetime
- 1998-08-20 ES ES98306691T patent/ES2185117T3/es not_active Expired - Lifetime
- 1998-08-21 CA CA2246033A patent/CA2246033C/en not_active Expired - Fee Related
- 1998-08-21 RU RU98116128/14A patent/RU2209080C2/ru not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69808402T2 (de) | 2003-07-03 |
| AU8082698A (en) | 1999-03-04 |
| ATE225184T1 (de) | 2002-10-15 |
| DE69808402D1 (de) | 2002-11-07 |
| ES2185117T3 (es) | 2003-04-16 |
| AU735216B2 (en) | 2001-07-05 |
| US6063378A (en) | 2000-05-16 |
| RU2209080C2 (ru) | 2003-07-27 |
| CA2246033C (en) | 2012-12-04 |
| EP0900569A3 (de) | 1999-04-07 |
| EP0900569A2 (de) | 1999-03-10 |
| EP0900569B1 (de) | 2002-10-02 |
| CA2246033A1 (en) | 1999-02-22 |
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