DK0900569T3 - Terapeutisk middel til behandling af herniaramt intervertebral diskus - Google Patents

Terapeutisk middel til behandling af herniaramt intervertebral diskus

Info

Publication number
DK0900569T3
DK0900569T3 DK98306691T DK98306691T DK0900569T3 DK 0900569 T3 DK0900569 T3 DK 0900569T3 DK 98306691 T DK98306691 T DK 98306691T DK 98306691 T DK98306691 T DK 98306691T DK 0900569 T3 DK0900569 T3 DK 0900569T3
Authority
DK
Denmark
Prior art keywords
treatment
intervertebral disc
herniaric
therapeutic agent
epidurally
Prior art date
Application number
DK98306691T
Other languages
Danish (da)
English (en)
Inventor
Yutaka Nohara
Hiroki Ishikawa
Original Assignee
Seikagaku Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Kogyo Co Ltd filed Critical Seikagaku Kogyo Co Ltd
Application granted granted Critical
Publication of DK0900569T3 publication Critical patent/DK0900569T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51—Lyases (4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK98306691T 1997-08-22 1998-08-20 Terapeutisk middel til behandling af herniaramt intervertebral diskus DK0900569T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22687297 1997-08-22

Publications (1)

Publication Number Publication Date
DK0900569T3 true DK0900569T3 (da) 2003-01-27

Family

ID=16851905

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98306691T DK0900569T3 (da) 1997-08-22 1998-08-20 Terapeutisk middel til behandling af herniaramt intervertebral diskus

Country Status (9)

Country Link
US (1) US6063378A (de)
EP (1) EP0900569B1 (de)
AT (1) ATE225184T1 (de)
AU (1) AU735216B2 (de)
CA (1) CA2246033C (de)
DE (1) DE69808402T2 (de)
DK (1) DK0900569T3 (de)
ES (1) ES2185117T3 (de)
RU (1) RU2209080C2 (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69933686T2 (de) * 1998-10-06 2007-08-23 Rush University Medical Center, Chicago Zusammensetzung zur verwendung in der chemonukleolyse
US6783546B2 (en) 1999-09-13 2004-08-31 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device
US6371984B1 (en) 1999-09-13 2002-04-16 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device
US7935147B2 (en) 1999-10-20 2011-05-03 Anulex Technologies, Inc. Method and apparatus for enhanced delivery of treatment device to the intervertebral disc annulus
US8632590B2 (en) 1999-10-20 2014-01-21 Anulex Technologies, Inc. Apparatus and methods for the treatment of the intervertebral disc
US7004970B2 (en) 1999-10-20 2006-02-28 Anulex Technologies, Inc. Methods and devices for spinal disc annulus reconstruction and repair
US7615076B2 (en) 1999-10-20 2009-11-10 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US6592625B2 (en) 1999-10-20 2003-07-15 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and spinal disc annulus stent
US8128698B2 (en) 1999-10-20 2012-03-06 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US7951201B2 (en) 1999-10-20 2011-05-31 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US7052516B2 (en) 1999-10-20 2006-05-30 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and deformable spinal disc annulus stent
US6805695B2 (en) 2000-04-04 2004-10-19 Spinalabs, Llc Devices and methods for annular repair of intervertebral discs
US20030069639A1 (en) * 2001-04-14 2003-04-10 Tom Sander Methods and compositions for repair or replacement of joints and soft tissues
JP3993855B2 (ja) * 2001-11-01 2007-10-17 スパイン・ウェイブ・インコーポレーテッド 脊椎椎間板の回復のための装置
JP4125234B2 (ja) 2001-11-01 2008-07-30 スパイン・ウェイブ・インコーポレーテッド 椎間板間の終板の前処理のための装置及び方法
EP1575548B1 (de) * 2002-05-04 2011-03-09 Acorda Therapeutics, Inc. Zusammensetzungen und verfahren zur förderung des neuronalen wachstums
CA2493509C (en) * 2002-06-03 2010-03-09 Massachusetts Institute Of Technology Rationally designed polysaccharide lyases derived from chondroitinase b
US7163545B2 (en) * 2002-07-29 2007-01-16 Mayo Foundation For Medical Education And Research Spinal cord surgical implant
EP1530643B1 (de) * 2002-08-15 2011-05-04 Acorda Therapeutics, Inc. Chimärisches protein
US20070134227A1 (en) * 2003-03-31 2007-06-14 Seikagaku Corporation Catalyst for cleaving sugar chain
MXPA05012305A (es) * 2003-05-16 2006-04-18 Acorda Therapeutics Inc Composiciones y metodos para el tratamiento de lesiones del snc.
US7959914B2 (en) 2003-05-16 2011-06-14 Acorda Therapeutics, Inc. Methods of reducing extravasation of inflammatory cells
US7429375B2 (en) 2003-05-16 2008-09-30 Acorda Therapeutics, Inc. Proteoglycan degrading mutants for the treatment of CNS
US7169405B2 (en) * 2003-08-06 2007-01-30 Warsaw Orthopedic, Inc. Methods and devices for the treatment of intervertebral discs
EP1729672A2 (de) 2004-01-08 2006-12-13 Spine Wave, Inc. Vorrichtung und verfahren zum injizieren von fliessendem material an einer auseinandergezogenen gewebestelle
ES2411504T3 (es) * 2004-05-18 2013-07-05 Acorda Therapeutics, Inc. Métodos de purificación de condroitinasa y formulaciones estables de la misma
US8337557B2 (en) * 2004-06-29 2012-12-25 Spine Wave, Inc. Apparatus and kit for injecting a curable biomaterial into an intervertebral space
US9968120B2 (en) * 2006-05-17 2018-05-15 Dsm Nutritional Products Ag Homogenized formulations containing microcapsules and methods of making and using thereof
WO2007038548A2 (en) * 2005-09-26 2007-04-05 Acorda Therapeutics, Inc. Compositions and methods of using chondroitinase abci mutants
US7879027B2 (en) * 2006-04-24 2011-02-01 Warsaw Orthopedic, Inc. Controlled release devices for fusion of osteal structures
US7771414B2 (en) * 2006-04-24 2010-08-10 Warsaw Orthopedic, Inc. Controlled release devices for therapeutic treatments of spinal discs
US8642059B2 (en) 2006-04-24 2014-02-04 Warsaw Orthopedic, Inc. Controlled release systems and methods for intervertebral discs
US8642060B2 (en) * 2006-04-24 2014-02-04 Warsaw Orthopedic, Inc. Controlled release systems and methods for osteal growth
EP2450442B1 (de) 2006-10-10 2017-07-19 Acorda Therapeutics, Inc. Zusammensetzungen und verfahren zur verwendung von chondroitinase-abci-mutanten
US8163022B2 (en) 2008-10-14 2012-04-24 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US8460319B2 (en) 2010-01-11 2013-06-11 Anulex Technologies, Inc. Intervertebral disc annulus repair system and method
ES2896060T3 (es) 2010-06-25 2022-02-23 Shire Human Genetic Therapies Métodos y composiciones para la administración al SNC de arilsulfatasa A
CA2805413A1 (en) 2010-06-25 2011-12-29 Shire Human Genetic Therapies, Inc. Methods and compositions for cns delivery of heparan n-sulfatase
EP2588130B1 (de) 2010-06-25 2016-08-17 Shire Human Genetic Therapies, Inc. Abgabe therapeutischer mittel in das zns
AU2011270670B2 (en) * 2010-06-25 2017-01-12 Takeda Pharmaceutical Company Limited Methods and compositions for CNS delivery of arylsulfatase A
UA115649C2 (uk) * 2010-06-25 2017-12-11 Шае Хюмен Дженетік Терапіс, Інк. Способи та композиції для доставки до цнс ідуронат-2-сульфатази
CN111420040A (zh) 2010-12-13 2020-07-17 生化学工业株式会社 椎间盘突出治疗剂
WO2013096899A2 (en) 2011-12-23 2013-06-27 Shire Human Genetic Therapies, Inc. Stable formulations for cns delivery of arylsulfatase a
US9737294B2 (en) 2013-01-28 2017-08-22 Cartiva, Inc. Method and system for orthopedic repair
WO2014117107A1 (en) 2013-01-28 2014-07-31 Cartiva, Inc. Systems and methods for orthopedic repair
PL3119386T3 (pl) * 2014-03-20 2019-12-31 Stayble Therapeutics Ab Kompozycja do zastosowania w leczeniu bólu związanego z krążkami międzykręgowymi

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4696816A (en) * 1985-11-07 1987-09-29 Brown Mark D Method for treating intervertebral disc displacement with enzymes
RU2021812C1 (ru) * 1992-04-13 1994-10-30 Всесоюзный научно-исследовательский институт технологии кровезаменителей и гормональных препаратов Средство для лечения артрологических заболеваний
US5496718A (en) * 1992-06-26 1996-03-05 Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) Chondroitinase ABC isolated from proteus vulgaris ATCC 6896
JP3419811B2 (ja) * 1993-02-24 2003-06-23 マルハ株式会社 コンドロイチナーゼ遺伝子
US6228998B1 (en) * 1994-07-22 2001-05-08 Seikagaku Kogyo Kabushiki Kaisha Amino spacered glycosaminoglycan derivatives and their use in copolymerization with acrylamide
EP0875253B1 (de) * 1997-05-02 2005-04-06 Seikagaku Corporation Chondroitinase enthaltende Zusammensetzungen

Also Published As

Publication number Publication date
AU8082698A (en) 1999-03-04
ES2185117T3 (es) 2003-04-16
DE69808402T2 (de) 2003-07-03
AU735216B2 (en) 2001-07-05
EP0900569A3 (de) 1999-04-07
DE69808402D1 (de) 2002-11-07
CA2246033A1 (en) 1999-02-22
EP0900569A2 (de) 1999-03-10
CA2246033C (en) 2012-12-04
RU2209080C2 (ru) 2003-07-27
EP0900569B1 (de) 2002-10-02
US6063378A (en) 2000-05-16
ATE225184T1 (de) 2002-10-15

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