DK0900569T3 - Terapeutisk middel til behandling af herniaramt intervertebral diskus - Google Patents

Terapeutisk middel til behandling af herniaramt intervertebral diskus

Info

Publication number
DK0900569T3
DK0900569T3 DK98306691T DK98306691T DK0900569T3 DK 0900569 T3 DK0900569 T3 DK 0900569T3 DK 98306691 T DK98306691 T DK 98306691T DK 98306691 T DK98306691 T DK 98306691T DK 0900569 T3 DK0900569 T3 DK 0900569T3
Authority
DK
Denmark
Prior art keywords
treatment
intervertebral disc
herniaric
therapeutic agent
epidurally
Prior art date
Application number
DK98306691T
Other languages
English (en)
Inventor
Yutaka Nohara
Hiroki Ishikawa
Original Assignee
Seikagaku Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Kogyo Co Ltd filed Critical Seikagaku Kogyo Co Ltd
Application granted granted Critical
Publication of DK0900569T3 publication Critical patent/DK0900569T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51—Lyases (4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK98306691T 1997-08-22 1998-08-20 Terapeutisk middel til behandling af herniaramt intervertebral diskus DK0900569T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22687297 1997-08-22

Publications (1)

Publication Number Publication Date
DK0900569T3 true DK0900569T3 (da) 2003-01-27

Family

ID=16851905

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98306691T DK0900569T3 (da) 1997-08-22 1998-08-20 Terapeutisk middel til behandling af herniaramt intervertebral diskus

Country Status (9)

Country Link
US (1) US6063378A (da)
EP (1) EP0900569B1 (da)
AT (1) ATE225184T1 (da)
AU (1) AU735216B2 (da)
CA (1) CA2246033C (da)
DE (1) DE69808402T2 (da)
DK (1) DK0900569T3 (da)
ES (1) ES2185117T3 (da)
RU (1) RU2209080C2 (da)

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EP2374870B1 (en) * 1998-10-06 2014-04-23 Stryker Corporation Composition comprising an osteogenic protein selected from the group consisting of OP-2, OP-3, BMP-2, BMP-3, BMP-4, BMP-5, BMP-6, BMP-9, BMP-10, BMP-11, BMP-15, BMP-3B, DPP, Vg-1, Vgr-1, 60A protein, GDF-1, GDF-2, GDF-3, GDF-6, GDF-7, GDF-8, GDF-9, GDF-10, and GDF-11 for use in repairing a defect locus in nonarticular cartilage
US6371984B1 (en) * 1999-09-13 2002-04-16 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device
US6783546B2 (en) 1999-09-13 2004-08-31 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device
US6592625B2 (en) 1999-10-20 2003-07-15 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and spinal disc annulus stent
US7935147B2 (en) 1999-10-20 2011-05-03 Anulex Technologies, Inc. Method and apparatus for enhanced delivery of treatment device to the intervertebral disc annulus
US7052516B2 (en) 1999-10-20 2006-05-30 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and deformable spinal disc annulus stent
US8632590B2 (en) 1999-10-20 2014-01-21 Anulex Technologies, Inc. Apparatus and methods for the treatment of the intervertebral disc
US8128698B2 (en) 1999-10-20 2012-03-06 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US7951201B2 (en) 1999-10-20 2011-05-31 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US7615076B2 (en) 1999-10-20 2009-11-10 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US7004970B2 (en) 1999-10-20 2006-02-28 Anulex Technologies, Inc. Methods and devices for spinal disc annulus reconstruction and repair
US6805695B2 (en) 2000-04-04 2004-10-19 Spinalabs, Llc Devices and methods for annular repair of intervertebral discs
US20030069639A1 (en) * 2001-04-14 2003-04-10 Tom Sander Methods and compositions for repair or replacement of joints and soft tissues
WO2003037166A2 (en) * 2001-11-01 2003-05-08 Boyd Lawrence M Devices and methods for the restoration of a spinal disc
AU2002350026A1 (en) 2001-11-01 2003-05-12 Lawrence M. Boyd System and method for the pretreatment of the endplates of an intervertebral disc
ATE500842T1 (de) * 2002-05-04 2011-03-15 Acorda Therapeutics Inc Zusammensetzungen und verfahren zur förderung des neuronalen wachstums
AU2003243396A1 (en) * 2002-06-03 2003-12-19 Massachusetts Institute Of Technology Rationally designed polysaccharide lyases derived from chondroitinase b
US7163545B2 (en) * 2002-07-29 2007-01-16 Mayo Foundation For Medical Education And Research Spinal cord surgical implant
EP1530643B1 (en) * 2002-08-15 2011-05-04 Acorda Therapeutics, Inc. Chimeric protein
EP1616955A4 (en) * 2003-03-31 2006-08-30 Seikagaku Kogyo Co Ltd CATALYST FOR CUTTING OF SUGAR CHAINS
CA2525804C (en) * 2003-05-16 2017-04-25 Acorda Therapeutics, Inc. Use of chondroitinase abc enzyme for the treatment of cns injuries
EP3211084B1 (en) 2003-05-16 2019-03-27 Acorda Therapeutics, Inc. Proteoglycan degrading mutants for treatment of cns
US7959914B2 (en) 2003-05-16 2011-06-14 Acorda Therapeutics, Inc. Methods of reducing extravasation of inflammatory cells
US7169405B2 (en) * 2003-08-06 2007-01-30 Warsaw Orthopedic, Inc. Methods and devices for the treatment of intervertebral discs
JP4440939B2 (ja) 2004-01-08 2010-03-24 スパイン・ウェイブ・インコーポレーテッド 伸延した組織部位に流動性材料を注入する装置及び方法
US8226941B2 (en) * 2004-05-18 2012-07-24 Acorda Therapeutics, Inc. Methods of purifying chondroitinase and stable formulations thereof
US7740660B2 (en) * 2004-06-29 2010-06-22 Spine Wave, Inc. Methods for treating defects and injuries of an intervertebral disc
US9968120B2 (en) * 2006-05-17 2018-05-15 Dsm Nutritional Products Ag Homogenized formulations containing microcapsules and methods of making and using thereof
WO2007038548A2 (en) 2005-09-26 2007-04-05 Acorda Therapeutics, Inc. Compositions and methods of using chondroitinase abci mutants
US8642059B2 (en) 2006-04-24 2014-02-04 Warsaw Orthopedic, Inc. Controlled release systems and methods for intervertebral discs
US7771414B2 (en) * 2006-04-24 2010-08-10 Warsaw Orthopedic, Inc. Controlled release devices for therapeutic treatments of spinal discs
US8642060B2 (en) * 2006-04-24 2014-02-04 Warsaw Orthopedic, Inc. Controlled release systems and methods for osteal growth
US7879027B2 (en) * 2006-04-24 2011-02-01 Warsaw Orthopedic, Inc. Controlled release devices for fusion of osteal structures
CA3009034C (en) * 2006-10-10 2020-08-18 Acorda Therapeutics, Inc. Compositions and methods of using chondroitinase abci mutants
US8163022B2 (en) 2008-10-14 2012-04-24 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US8652153B2 (en) 2010-01-11 2014-02-18 Anulex Technologies, Inc. Intervertebral disc annulus repair system and bone anchor delivery tool
UA115649C2 (uk) * 2010-06-25 2017-12-11 Шае Хюмен Дженетік Терапіс, Інк. Способи та композиції для доставки до цнс ідуронат-2-сульфатази
SMT201600385T1 (it) 2010-06-25 2017-03-08 Shire Human Genetic Therapies Trasporto di agenti terapeutici all’snc
PT2588130T (pt) 2010-06-25 2016-11-25 Shire Human Genetic Therapies Entrega de agentes terapêuticos no cns
KR102720061B1 (ko) * 2010-06-25 2024-10-22 다케다 파머수티컬 컴패니 리미티드 아릴설파타제 a의 cns 전달을 위한 방법들 및 조성물들
BR112012033197A2 (pt) 2010-06-25 2017-06-06 Shire Human Genetic Therapies métodos e composições para liberação de cns de n-sulfatase de heparano.
KR20170004032A (ko) * 2010-12-13 2017-01-10 세이가가쿠 고교 가부시키가이샤 추간판 헤르니아 치료제
EP2793922B1 (en) 2011-12-23 2019-10-30 Shire Human Genetic Therapies, Inc. Stable formulations for cns delivery of arylsulfatase a
US9737294B2 (en) 2013-01-28 2017-08-22 Cartiva, Inc. Method and system for orthopedic repair
EP2948068A4 (en) 2013-01-28 2016-09-28 Cartiva Inc SYSTEMS AND METHOD FOR ORTHOPEDIC REPAIRS
RU2682675C2 (ru) * 2014-03-20 2019-03-20 Стайбле Терапеутикс Аб Композиция для применения при лечении боли, связанной с межпозвоночным диском

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4696816A (en) * 1985-11-07 1987-09-29 Brown Mark D Method for treating intervertebral disc displacement with enzymes
RU2021812C1 (ru) * 1992-04-13 1994-10-30 Всесоюзный научно-исследовательский институт технологии кровезаменителей и гормональных препаратов Средство для лечения артрологических заболеваний
US5496718A (en) * 1992-06-26 1996-03-05 Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) Chondroitinase ABC isolated from proteus vulgaris ATCC 6896
JP3419811B2 (ja) * 1993-02-24 2003-06-23 マルハ株式会社 コンドロイチナーゼ遺伝子
US6228998B1 (en) * 1994-07-22 2001-05-08 Seikagaku Kogyo Kabushiki Kaisha Amino spacered glycosaminoglycan derivatives and their use in copolymerization with acrylamide
EP0875253B1 (en) * 1997-05-02 2005-04-06 Seikagaku Corporation Chondroitinase compositions

Also Published As

Publication number Publication date
CA2246033A1 (en) 1999-02-22
EP0900569A2 (en) 1999-03-10
ES2185117T3 (es) 2003-04-16
EP0900569B1 (en) 2002-10-02
DE69808402T2 (de) 2003-07-03
EP0900569A3 (en) 1999-04-07
AU735216B2 (en) 2001-07-05
CA2246033C (en) 2012-12-04
ATE225184T1 (de) 2002-10-15
AU8082698A (en) 1999-03-04
US6063378A (en) 2000-05-16
DE69808402D1 (de) 2002-11-07
RU2209080C2 (ru) 2003-07-27

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