DK0892802T3 - Spiro[cyclopent[b]indol-piperidiner] og N-phenyl-hydrazon-mellemprodukter til deres fremstilling, begge som acetylcholinesterase- og mao-inhibitorer - Google Patents
Spiro[cyclopent[b]indol-piperidiner] og N-phenyl-hydrazon-mellemprodukter til deres fremstilling, begge som acetylcholinesterase- og mao-inhibitorerInfo
- Publication number
- DK0892802T3 DK0892802T3 DK97908068T DK97908068T DK0892802T3 DK 0892802 T3 DK0892802 T3 DK 0892802T3 DK 97908068 T DK97908068 T DK 97908068T DK 97908068 T DK97908068 T DK 97908068T DK 0892802 T3 DK0892802 T3 DK 0892802T3
- Authority
- DK
- Denmark
- Prior art keywords
- cyclopent
- acetylcholinesterase
- piperidines
- spiro
- indole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Psychiatry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63064196A | 1996-04-10 | 1996-04-10 | |
| PCT/US1997/003864 WO1997037992A2 (en) | 1996-04-10 | 1997-03-10 | Spiro[cyclopent[b]indole-piperidines] and n-phenyl-hydrazon intermediates for their preparation, both being acetylcholinesterase and mao inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0892802T3 true DK0892802T3 (da) | 2003-12-01 |
Family
ID=24527997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97908068T DK0892802T3 (da) | 1996-04-10 | 1997-03-10 | Spiro[cyclopent[b]indol-piperidiner] og N-phenyl-hydrazon-mellemprodukter til deres fremstilling, begge som acetylcholinesterase- og mao-inhibitorer |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0892802B1 (de) |
| JP (1) | JP3615225B2 (de) |
| KR (1) | KR100270145B1 (de) |
| CN (1) | CN1233249A (de) |
| AR (1) | AR006553A1 (de) |
| AT (1) | ATE252581T1 (de) |
| AU (1) | AU708124B2 (de) |
| BR (1) | BR9708563A (de) |
| CA (1) | CA2251545C (de) |
| DE (1) | DE69725713T2 (de) |
| DK (1) | DK0892802T3 (de) |
| ES (1) | ES2207718T3 (de) |
| HU (1) | HUP9902755A3 (de) |
| IL (1) | IL126003A0 (de) |
| NO (1) | NO984739L (de) |
| PT (1) | PT892802E (de) |
| WO (1) | WO1997037992A2 (de) |
| ZA (1) | ZA972984B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100639543B1 (ko) | 1998-09-30 | 2006-10-31 | 다케다 야쿠힌 고교 가부시키가이샤 | 방광 배출력 개선제 |
| CN102762554A (zh) | 2010-02-16 | 2012-10-31 | 辉瑞大药厂 | 5-ht4受体的部分激动剂(r)-4-((4-((4-(四氢呋喃-3-基氧基)苯并[d]异*唑-3-基氧基)甲基)哌啶-1-基)甲基)四氢-2h-吡喃-4-醇 |
| US10562857B2 (en) | 2015-11-12 | 2020-02-18 | Afasci, Inc. | Ion channel inhibitory compounds, pharmaceutical formulations, and uses |
| WO2020048827A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Aktiengesellschaft | 1, 3, 9-triazaspiro[5.5] undecan-2-one compounds |
| TW202024083A (zh) | 2018-09-03 | 2020-07-01 | 德商拜耳廠股份有限公司 | 3,9-二氮雜螺[5.5]十一烷化合物 |
| WO2020048828A1 (en) | 2018-09-03 | 2020-03-12 | Bayer Pharma Aktiengesellschaft | 5-heteroaryl-3,9-diazaspiro[5.5]undecane compounds |
-
1997
- 1997-03-01 IL IL12600397A patent/IL126003A0/xx unknown
- 1997-03-10 AU AU19909/97A patent/AU708124B2/en not_active Ceased
- 1997-03-10 ES ES97908068T patent/ES2207718T3/es not_active Expired - Lifetime
- 1997-03-10 WO PCT/US1997/003864 patent/WO1997037992A2/en active IP Right Grant
- 1997-03-10 PT PT97908068T patent/PT892802E/pt unknown
- 1997-03-10 DE DE69725713T patent/DE69725713T2/de not_active Expired - Fee Related
- 1997-03-10 HU HU9902755A patent/HUP9902755A3/hu unknown
- 1997-03-10 AT AT97908068T patent/ATE252581T1/de not_active IP Right Cessation
- 1997-03-10 DK DK97908068T patent/DK0892802T3/da active
- 1997-03-10 BR BR9708563A patent/BR9708563A/pt not_active IP Right Cessation
- 1997-03-10 KR KR1019980708047A patent/KR100270145B1/ko not_active IP Right Cessation
- 1997-03-10 JP JP53619797A patent/JP3615225B2/ja not_active Expired - Fee Related
- 1997-03-10 CN CN97193690A patent/CN1233249A/zh active Pending
- 1997-03-10 CA CA002251545A patent/CA2251545C/en not_active Expired - Fee Related
- 1997-03-10 EP EP97908068A patent/EP0892802B1/de not_active Expired - Lifetime
- 1997-04-08 ZA ZA9702984A patent/ZA972984B/xx unknown
- 1997-04-08 AR ARP970101376A patent/AR006553A1/es not_active Application Discontinuation
-
1998
- 1998-10-09 NO NO984739A patent/NO984739L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR100270145B1 (ko) | 2000-11-01 |
| HUP9902755A3 (en) | 2000-05-29 |
| ES2207718T3 (es) | 2004-06-01 |
| AU1990997A (en) | 1997-10-29 |
| IL126003A0 (en) | 1999-04-11 |
| CA2251545A1 (en) | 1997-10-16 |
| PT892802E (pt) | 2004-03-31 |
| CN1233249A (zh) | 1999-10-27 |
| BR9708563A (pt) | 1999-08-03 |
| DE69725713D1 (de) | 2003-11-27 |
| KR20000005328A (ko) | 2000-01-25 |
| EP0892802A1 (de) | 1999-01-27 |
| AR006553A1 (es) | 1999-09-08 |
| ZA972984B (en) | 1997-11-03 |
| NO984739D0 (no) | 1998-10-09 |
| NO984739L (no) | 1998-12-09 |
| CA2251545C (en) | 2002-01-08 |
| EP0892802B1 (de) | 2003-10-22 |
| WO1997037992A2 (en) | 1997-10-16 |
| ATE252581T1 (de) | 2003-11-15 |
| HUP9902755A2 (hu) | 2000-03-28 |
| AU708124B2 (en) | 1999-07-29 |
| JP3615225B2 (ja) | 2005-02-02 |
| DE69725713T2 (de) | 2004-05-13 |
| JP2002509520A (ja) | 2002-03-26 |
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