DK0888372T3 - Oligonukleotid-anthracyclin- og oligonukleotid-anthracyclinon-konjugater - Google Patents
Oligonukleotid-anthracyclin- og oligonukleotid-anthracyclinon-konjugaterInfo
- Publication number
- DK0888372T3 DK0888372T3 DK97914227T DK97914227T DK0888372T3 DK 0888372 T3 DK0888372 T3 DK 0888372T3 DK 97914227 T DK97914227 T DK 97914227T DK 97914227 T DK97914227 T DK 97914227T DK 0888372 T3 DK0888372 T3 DK 0888372T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- oligonucleotide
- conjugates
- anthracyclinone
- anthracycline
- Prior art date
Links
- 229940045799 anthracyclines and related substance Drugs 0.000 title abstract 2
- TWCMVXMQHSVIOJ-UHFFFAOYSA-N Aglycone of yadanzioside D Natural products COC(=O)C12OCC34C(CC5C(=CC(O)C(O)C5(C)C3C(O)C1O)C)OC(=O)C(OC(=O)C)C24 TWCMVXMQHSVIOJ-UHFFFAOYSA-N 0.000 abstract 1
- PLMKQQMDOMTZGG-UHFFFAOYSA-N Astrantiagenin E-methylester Natural products CC12CCC(O)C(C)(CO)C1CCC1(C)C2CC=C2C3CC(C)(C)CCC3(C(=O)OC)CCC21C PLMKQQMDOMTZGG-UHFFFAOYSA-N 0.000 abstract 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- PFOARMALXZGCHY-UHFFFAOYSA-N homoegonol Natural products C1=C(OC)C(OC)=CC=C1C1=CC2=CC(CCCO)=CC(OC)=C2O1 PFOARMALXZGCHY-UHFFFAOYSA-N 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000035897 transcription Effects 0.000 abstract 1
- 238000013518 transcription Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catching Or Destruction (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT96FI000044A IT1286567B1 (it) | 1996-03-13 | 1996-03-13 | Coniugati oligonucleotide-antraciclina o oligonucleotide- antraciclinone |
| PCT/EP1997/001246 WO1997033897A1 (en) | 1996-03-13 | 1997-03-12 | Oligonucleotide-anthracycline and oligonucleotide-anthracyclinone conjugates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0888372T3 true DK0888372T3 (da) | 2001-11-05 |
Family
ID=11351526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97914227T DK0888372T3 (da) | 1996-03-13 | 1997-03-12 | Oligonukleotid-anthracyclin- og oligonukleotid-anthracyclinon-konjugater |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6160102A (enExample) |
| EP (1) | EP0888372B1 (enExample) |
| AT (1) | ATE204289T1 (enExample) |
| AU (1) | AU2155497A (enExample) |
| CA (1) | CA2248900A1 (enExample) |
| DE (1) | DE69706150T2 (enExample) |
| DK (1) | DK0888372T3 (enExample) |
| ES (1) | ES2162267T3 (enExample) |
| IT (1) | IT1286567B1 (enExample) |
| PT (1) | PT888372E (enExample) |
| WO (1) | WO1997033897A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000052210A2 (en) * | 1999-03-01 | 2000-09-08 | Variagenics, Inc. | Methods for targeting rna molecules |
-
1996
- 1996-03-13 IT IT96FI000044A patent/IT1286567B1/it active IP Right Grant
-
1997
- 1997-03-12 AU AU21554/97A patent/AU2155497A/en not_active Abandoned
- 1997-03-12 EP EP97914227A patent/EP0888372B1/en not_active Expired - Lifetime
- 1997-03-12 DK DK97914227T patent/DK0888372T3/da active
- 1997-03-12 WO PCT/EP1997/001246 patent/WO1997033897A1/en not_active Ceased
- 1997-03-12 AT AT97914227T patent/ATE204289T1/de not_active IP Right Cessation
- 1997-03-12 ES ES97914227T patent/ES2162267T3/es not_active Expired - Lifetime
- 1997-03-12 DE DE69706150T patent/DE69706150T2/de not_active Expired - Fee Related
- 1997-03-12 CA CA002248900A patent/CA2248900A1/en not_active Abandoned
- 1997-03-12 PT PT97914227T patent/PT888372E/pt unknown
- 1997-03-12 US US09/142,521 patent/US6160102A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69706150D1 (de) | 2001-09-20 |
| ITFI960044A1 (it) | 1996-06-13 |
| ITFI960044A0 (enExample) | 1996-03-13 |
| CA2248900A1 (en) | 1997-09-18 |
| EP0888372A1 (en) | 1999-01-07 |
| DE69706150T2 (de) | 2002-04-11 |
| WO1997033897A1 (en) | 1997-09-18 |
| IT1286567B1 (it) | 1998-07-15 |
| ATE204289T1 (de) | 2001-09-15 |
| PT888372E (pt) | 2002-01-30 |
| EP0888372B1 (en) | 2001-08-16 |
| ES2162267T3 (es) | 2001-12-16 |
| AU2155497A (en) | 1997-10-01 |
| US6160102A (en) | 2000-12-12 |
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