CA2248900A1 - Oligonucleotide-anthracycline and oligonucleotide-anthracyclinone conjugates - Google Patents
Oligonucleotide-anthracycline and oligonucleotide-anthracyclinone conjugates Download PDFInfo
- Publication number
- CA2248900A1 CA2248900A1 CA002248900A CA2248900A CA2248900A1 CA 2248900 A1 CA2248900 A1 CA 2248900A1 CA 002248900 A CA002248900 A CA 002248900A CA 2248900 A CA2248900 A CA 2248900A CA 2248900 A1 CA2248900 A1 CA 2248900A1
- Authority
- CA
- Canada
- Prior art keywords
- oligonucleotide
- anthracycline
- conjugates according
- conjugates
- aglycone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Catching Or Destruction (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT96FI000044A IT1286567B1 (it) | 1996-03-13 | 1996-03-13 | Coniugati oligonucleotide-antraciclina o oligonucleotide- antraciclinone |
| ITF196A000044 | 1996-03-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2248900A1 true CA2248900A1 (en) | 1997-09-18 |
Family
ID=11351526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002248900A Abandoned CA2248900A1 (en) | 1996-03-13 | 1997-03-12 | Oligonucleotide-anthracycline and oligonucleotide-anthracyclinone conjugates |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6160102A (enExample) |
| EP (1) | EP0888372B1 (enExample) |
| AT (1) | ATE204289T1 (enExample) |
| AU (1) | AU2155497A (enExample) |
| CA (1) | CA2248900A1 (enExample) |
| DE (1) | DE69706150T2 (enExample) |
| DK (1) | DK0888372T3 (enExample) |
| ES (1) | ES2162267T3 (enExample) |
| IT (1) | IT1286567B1 (enExample) |
| PT (1) | PT888372E (enExample) |
| WO (1) | WO1997033897A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2363077A1 (en) | 1999-03-01 | 2000-09-08 | Variagenics, Inc. | Methods for targeting rna molecules |
-
1996
- 1996-03-13 IT IT96FI000044A patent/IT1286567B1/it active IP Right Grant
-
1997
- 1997-03-12 AT AT97914227T patent/ATE204289T1/de not_active IP Right Cessation
- 1997-03-12 DE DE69706150T patent/DE69706150T2/de not_active Expired - Fee Related
- 1997-03-12 WO PCT/EP1997/001246 patent/WO1997033897A1/en not_active Ceased
- 1997-03-12 ES ES97914227T patent/ES2162267T3/es not_active Expired - Lifetime
- 1997-03-12 CA CA002248900A patent/CA2248900A1/en not_active Abandoned
- 1997-03-12 US US09/142,521 patent/US6160102A/en not_active Expired - Fee Related
- 1997-03-12 PT PT97914227T patent/PT888372E/pt unknown
- 1997-03-12 AU AU21554/97A patent/AU2155497A/en not_active Abandoned
- 1997-03-12 DK DK97914227T patent/DK0888372T3/da active
- 1997-03-12 EP EP97914227A patent/EP0888372B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU2155497A (en) | 1997-10-01 |
| IT1286567B1 (it) | 1998-07-15 |
| DK0888372T3 (da) | 2001-11-05 |
| EP0888372A1 (en) | 1999-01-07 |
| ITFI960044A0 (enExample) | 1996-03-13 |
| US6160102A (en) | 2000-12-12 |
| DE69706150D1 (de) | 2001-09-20 |
| ES2162267T3 (es) | 2001-12-16 |
| PT888372E (pt) | 2002-01-30 |
| ITFI960044A1 (it) | 1996-06-13 |
| ATE204289T1 (de) | 2001-09-15 |
| EP0888372B1 (en) | 2001-08-16 |
| DE69706150T2 (de) | 2002-04-11 |
| WO1997033897A1 (en) | 1997-09-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Letsinger et al. | Use of a stilbenedicarboxamide bridge in stabilizing, monitoring, and photochemically altering folded conformations of oligonucleotides | |
| Sage et al. | Conformation of poly (dG-dC). poly (dG-dC) modified by the carcinogens N-acetoxy-N-acetyl-2-aminofluorene and N-hydroxy-N-2-aminofluorene. | |
| Mergny et al. | Fluorescence energy transfer as a probe for nucleic acid structures and sequences | |
| AU702309B2 (en) | Cationic oligonucleotides, and related methods of synthesis and use | |
| ES2399363T3 (es) | Compuestos y métodos para la síntesis y purificación de oligonucleótidos | |
| WO1997046568A1 (en) | Nucleic acid mediated electron transfer | |
| Garbesi et al. | Synthesis and binding properties of conjugates between oligodeoxynucleotides and daunorubicin derivatives | |
| Adinolfi et al. | Solid phase synthesis of oligonucleotides tethered to oligo-glucose phosphate tails | |
| EP1669464B1 (en) | Dna detection method using molecular beacon with the use of monomer fluorescence/excimer fluorescence switching of fluorescent molecule | |
| EP0888372B1 (en) | Oligonucleotide-anthracycline and oligonucleotide-anthracyclinone conjugates | |
| EP2475674B1 (en) | Probes comprising fluorescent artificial nucleobases and use thereof for detection of single base alteration | |
| Adinolfi et al. | Modulating the activity of oligonucleotides by carbohydrate conjugation: solid phase synthesis of sucrose-oligonucleotide hybrids | |
| Smith et al. | Adriamycin analogs. 2. Synthesis of 13-deoxyanthracyclines | |
| JP2000511160A (ja) | 多環芳香族基が結合した新規ヌクレオシドアナログ、その合成方法および使用 | |
| EP0358657A1 (en) | POLYDEOXYRIBONUCLEOTIDES, PHARMACEUTICAL COMPOSITIONS, USE AND PRODUCTION OF POLYDEOXYRIBONUCLEOTIDES. | |
| Meyer et al. | Phthalimide–Oxy Derivatives for 3′‐or 5′‐Conjugation of Oligonucleotides by Oxime Ligation and Circularization of DNA by “Bis‐or Tris‐Click” Oxime Ligation | |
| EP0372002A1 (en) | A covalent oligonucleotide-horseradish peroxidase conjugate | |
| JPH10505353A (ja) | オリゴヌクレオチド複合体、構成成分及びリボ核酸の分解方法 | |
| AU2024306089A1 (en) | Nucleic acid conjugates as well as preparation method therefor and use thereof | |
| Saha et al. | Diisopropylsilyl-linked oligonucleotide analogs: Solid-phase synthesis and physicochemical properties | |
| JP2001527515A (ja) | ３―置換された又は３，８―置換された１，１０―フェナントロリン及び電子移動又はエネルギー移動過程におけるその使用 | |
| US5650399A (en) | Reactive anthraquinone derivatives and conjugates thereof | |
| KR20020007379A (ko) | 신규 ８ａ 및 ９ａ-15-원 락탐 | |
| De Napoli et al. | Synthesis and characterization of new 3′-3′ linked oligodeoxyribonucleotides for alternate strand triple helix formation | |
| AU4317989A (en) | Phosphorothioate and normal oligodeoxynucleotides with 5'-linked acridine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |