DK0855391T3 - Hidtil ukendte isoquinolinderivater - Google Patents
Hidtil ukendte isoquinolinderivaterInfo
- Publication number
- DK0855391T3 DK0855391T3 DK97934731T DK97934731T DK0855391T3 DK 0855391 T3 DK0855391 T3 DK 0855391T3 DK 97934731 T DK97934731 T DK 97934731T DK 97934731 T DK97934731 T DK 97934731T DK 0855391 T3 DK0855391 T3 DK 0855391T3
- Authority
- DK
- Denmark
- Prior art keywords
- disease
- cell death
- isoquinoline derivatives
- compounds
- diseases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22327196 | 1996-08-07 | ||
| JP20842597A JP3243733B2 (ja) | 1996-08-07 | 1997-07-18 | 新規イソキノリン誘導体 |
| PCT/JP1997/002765 WO1998005648A1 (fr) | 1996-08-07 | 1997-08-07 | Derives d'isoquinoleine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0855391T3 true DK0855391T3 (da) | 2004-02-16 |
Family
ID=26516823
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97934731T DK0855391T3 (da) | 1996-08-07 | 1997-08-07 | Hidtil ukendte isoquinolinderivater |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5959107A (da) |
| EP (1) | EP0855391B1 (da) |
| JP (1) | JP3243733B2 (da) |
| AT (1) | ATE252082T1 (da) |
| AU (1) | AU734322B2 (da) |
| CA (1) | CA2234051C (da) |
| DE (1) | DE69725549T2 (da) |
| DK (1) | DK0855391T3 (da) |
| ES (1) | ES2206739T3 (da) |
| NZ (1) | NZ330117A (da) |
| WO (1) | WO1998005648A1 (da) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2751649B1 (fr) * | 1996-07-26 | 1998-08-28 | Adir | Nouveaux derives de benzimidazole, de benzoxazole et de benzothiazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US6583157B2 (en) | 1998-01-29 | 2003-06-24 | Tularik Inc. | Quinolinyl and benzothiazolyl modulators |
| WO1999038845A1 (en) | 1998-01-29 | 1999-08-05 | Tularik Inc. | Ppar-gamma modulators |
| AU779730B2 (en) * | 1999-06-30 | 2005-02-10 | Amgen, Inc. | Compounds for the modulation of PPARgamma activity |
| NZ530833A (en) * | 1999-06-30 | 2005-08-26 | Tularik Inc | Compounds for the modulation of PPARgamma activity |
| US7041691B1 (en) | 1999-06-30 | 2006-05-09 | Amgen Inc. | Compounds for the modulation of PPARγ activity |
| WO2001076592A1 (en) * | 2000-04-06 | 2001-10-18 | Acorda Therapeutics, Inc. | Compositions and methods for promoting neural regeneration |
| US6653332B2 (en) | 2000-05-03 | 2003-11-25 | Tularik Inc. | Combination therapeutic compositions and method of use |
| US20030171399A1 (en) | 2000-06-28 | 2003-09-11 | Tularik Inc. | Quinolinyl and benzothiazolyl modulators |
| ATE364382T1 (de) * | 2001-08-13 | 2007-07-15 | Max Planck Gesellschaft | Hemmer der aggregation von polyq |
| US6583284B1 (en) * | 2002-08-07 | 2003-06-24 | Optiva, Inc. | Anisotropic films based on sulfoderivatives of phenanthro-9′, 10′:2,3-quinoxaline and lyotropic liquid crystal systems and method for making |
| US20070027164A1 (en) * | 2003-01-29 | 2007-02-01 | Stockwell Brent R | Agents for treating neurodegenerative diseases |
| US20070078144A1 (en) * | 2003-01-29 | 2007-04-05 | Stockwell Brent R | Agents for treating neurodegenerative diseases |
| US7223761B2 (en) | 2003-10-03 | 2007-05-29 | Amgen Inc. | Salts and polymorphs of a potent antidiabetic compound |
| US7045177B2 (en) * | 2003-11-21 | 2006-05-16 | Nitto Denko Corporation | Sulfoderivatives of acenaphtho[1,2-b]quinoxaline, lyotropic liquid crystal and anisotropic film on their base |
| US20070161644A1 (en) * | 2005-01-25 | 2007-07-12 | Stockwell Brent R | Erastin analogs and uses thereof |
| WO2007149476A2 (en) * | 2006-06-19 | 2007-12-27 | Trustees Of Columbia University In The City Of New York | Assays for non-apoptotic cell death and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5753338B2 (da) * | 1973-08-07 | 1982-11-12 | ||
| SG64322A1 (en) * | 1991-05-10 | 1999-04-27 | Rhone Poulenc Rorer Int | Bis mono and bicyclic aryl and heteroaryl compounds which inhibit egf and/or pdgf receptor tyrosine kinase |
| JP2804393B2 (ja) * | 1991-07-31 | 1998-09-24 | 京セラ株式会社 | セラミックヒータ |
| EP0787493A1 (en) * | 1996-02-03 | 1997-08-06 | F. Hoffmann-La Roche Ag | Tetrahydroisoquinoline derivatives |
-
1997
- 1997-07-18 JP JP20842597A patent/JP3243733B2/ja not_active Expired - Fee Related
- 1997-08-07 AU AU37841/97A patent/AU734322B2/en not_active Ceased
- 1997-08-07 AT AT97934731T patent/ATE252082T1/de not_active IP Right Cessation
- 1997-08-07 DK DK97934731T patent/DK0855391T3/da active
- 1997-08-07 EP EP97934731A patent/EP0855391B1/en not_active Expired - Lifetime
- 1997-08-07 CA CA002234051A patent/CA2234051C/en not_active Expired - Fee Related
- 1997-08-07 ES ES97934731T patent/ES2206739T3/es not_active Expired - Lifetime
- 1997-08-07 DE DE69725549T patent/DE69725549T2/de not_active Expired - Fee Related
- 1997-08-07 US US09/051,404 patent/US5959107A/en not_active Expired - Fee Related
- 1997-08-07 WO PCT/JP1997/002765 patent/WO1998005648A1/ja active IP Right Grant
-
1998
- 1998-08-07 NZ NZ330117A patent/NZ330117A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0855391A4 (en) | 2000-07-19 |
| EP0855391B1 (en) | 2003-10-15 |
| ES2206739T3 (es) | 2004-05-16 |
| DE69725549T2 (de) | 2004-08-12 |
| AU734322B2 (en) | 2001-06-07 |
| CA2234051C (en) | 2002-09-03 |
| NZ330117A (en) | 1999-10-28 |
| JPH10101650A (ja) | 1998-04-21 |
| EP0855391A1 (en) | 1998-07-29 |
| JP3243733B2 (ja) | 2002-01-07 |
| WO1998005648A1 (fr) | 1998-02-12 |
| US5959107A (en) | 1999-09-28 |
| AU3784197A (en) | 1998-02-25 |
| CA2234051A1 (en) | 1998-02-12 |
| ATE252082T1 (de) | 2003-11-15 |
| DE69725549D1 (de) | 2003-11-20 |
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