DK0854707T3 - Faste lægemiddelformer, som opnåes ved ekstrusion af en isomalt indeholdende smeltet masse af en polymer og et biologisk virksomt stof - Google Patents
Faste lægemiddelformer, som opnåes ved ekstrusion af en isomalt indeholdende smeltet masse af en polymer og et biologisk virksomt stofInfo
- Publication number
- DK0854707T3 DK0854707T3 DK96934494T DK96934494T DK0854707T3 DK 0854707 T3 DK0854707 T3 DK 0854707T3 DK 96934494 T DK96934494 T DK 96934494T DK 96934494 T DK96934494 T DK 96934494T DK 0854707 T3 DK0854707 T3 DK 0854707T3
- Authority
- DK
- Denmark
- Prior art keywords
- extrusion
- isomal
- polymer
- active substance
- biologically active
- Prior art date
Links
- 238000001125 extrusion Methods 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title abstract 2
- 229940088623 biologically active substance Drugs 0.000 title 1
- 229920000642 polymer Polymers 0.000 title 1
- SERLAGPUMNYUCK-DCUALPFSSA-N 1-O-alpha-D-glucopyranosyl-D-mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O SERLAGPUMNYUCK-DCUALPFSSA-N 0.000 abstract 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 abstract 1
- 101100379081 Emericella variicolor andC gene Proteins 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 235000010439 isomalt Nutrition 0.000 abstract 1
- 239000000905 isomalt Substances 0.000 abstract 1
- HPIGCVXMBGOWTF-UHFFFAOYSA-N isomaltol Natural products CC(=O)C=1OC=CC=1O HPIGCVXMBGOWTF-UHFFFAOYSA-N 0.000 abstract 1
- 229940067606 lecithin Drugs 0.000 abstract 1
- 235000010445 lecithin Nutrition 0.000 abstract 1
- 239000000787 lecithin Substances 0.000 abstract 1
- 238000007493 shaping process Methods 0.000 abstract 1
- 229920003169 water-soluble polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19536394A DE19536394A1 (de) | 1995-09-29 | 1995-09-29 | Feste Arzneiformen, erhältlich durch Extrusion einer Isomalt enthaltenden Polymer-Wirkstoff-Schmelze |
PCT/EP1996/004262 WO1997012603A1 (de) | 1995-09-29 | 1996-09-30 | Feste arzneiformen, erhältlich durch extrusion einer isomalt enthaltenden polymer-wirkstoff-schmelze |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0854707T3 true DK0854707T3 (da) | 2002-12-16 |
Family
ID=7773633
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96934494T DK0854707T3 (da) | 1995-09-29 | 1996-09-30 | Faste lægemiddelformer, som opnåes ved ekstrusion af en isomalt indeholdende smeltet masse af en polymer og et biologisk virksomt stof |
Country Status (22)
Country | Link |
---|---|
US (1) | US6187342B1 (da) |
EP (1) | EP0854707B1 (da) |
JP (1) | JP4041163B2 (da) |
KR (1) | KR19990063853A (da) |
CN (1) | CN1200694C (da) |
AT (1) | ATE228355T1 (da) |
AU (1) | AU7282896A (da) |
BG (1) | BG102346A (da) |
BR (1) | BR9610799A (da) |
CA (1) | CA2230950C (da) |
CZ (1) | CZ95998A3 (da) |
DE (2) | DE19536394A1 (da) |
DK (1) | DK0854707T3 (da) |
ES (1) | ES2187678T3 (da) |
HU (1) | HUP9903384A3 (da) |
IL (1) | IL123250A (da) |
MX (1) | MX9801988A (da) |
NO (1) | NO981394L (da) |
RU (1) | RU2197228C2 (da) |
TW (1) | TW438599B (da) |
WO (1) | WO1997012603A1 (da) |
ZA (1) | ZA968130B (da) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19809242A1 (de) * | 1998-03-05 | 1999-09-09 | Basf Ag | Verfahren zur Herstellung von festen, sphärischen Formkörpern, enthaltend pharmazeutische Wirkstoffe in einer Bindemittelmatrix |
US6465009B1 (en) | 1998-03-18 | 2002-10-15 | Yamanouchi Pharmaceutical Co., Ltd. | Water soluble polymer-based rapidly dissolving tablets and production processes thereof |
EP1175205B1 (en) * | 1999-11-12 | 2006-06-14 | Abbott Laboratories | Solid dispersion comprising ritonavir, fenofibrate or griseofulvin |
US7364752B1 (en) | 1999-11-12 | 2008-04-29 | Abbott Laboratories | Solid dispersion pharamaceutical formulations |
US9522217B2 (en) | 2000-03-15 | 2016-12-20 | Orbusneich Medical, Inc. | Medical device with coating for capturing genetically-altered cells and methods for using same |
US8088060B2 (en) * | 2000-03-15 | 2012-01-03 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
US20070141107A1 (en) * | 2000-03-15 | 2007-06-21 | Orbusneich Medical, Inc. | Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device |
DE10026698A1 (de) * | 2000-05-30 | 2001-12-06 | Basf Ag | Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung |
WO2002064093A2 (en) * | 2001-02-15 | 2002-08-22 | King Pharmaceuticals, Inc. | Stabilized pharmaceutical and thyroid hormone compositions and method of preparation |
US20030032675A1 (en) * | 2001-02-15 | 2003-02-13 | Franz G. Andrew | Manufacture of thyroid hormone tablets having consistent active moiety amounts |
US6555581B1 (en) | 2001-02-15 | 2003-04-29 | Jones Pharma, Inc. | Levothyroxine compositions and methods |
US20030224047A1 (en) * | 2001-02-15 | 2003-12-04 | Franz G. Andrew | Levothyroxine compositions and methods |
PL364621A1 (en) * | 2001-03-26 | 2004-12-13 | Smithkline Beecham Corporation | Nicotine-containing oral dosage form |
FR2823974B1 (fr) * | 2001-04-25 | 2004-10-15 | Pf Medicament | Pastille medicamenteuse a liberation lente du principe actif |
US20030198667A1 (en) * | 2001-08-10 | 2003-10-23 | Franz Andrew G. | Methods of producing dispersible pharmaceutical compositions |
US20030180353A1 (en) * | 2001-08-10 | 2003-09-25 | Franz G. Andrew | Stabilized pharmaceutical compositions |
US20030198671A1 (en) * | 2001-08-10 | 2003-10-23 | Franz G. Andrew | Levothyroxine compositions having unique plasma AUC properties |
US20030190349A1 (en) * | 2001-08-10 | 2003-10-09 | Franz G. Andrew | Methods of stabilizing pharmaceutical compositions |
US20030199586A1 (en) * | 2001-08-14 | 2003-10-23 | Franz G. Andrew | Unique levothyroxine aqueous materials |
US20030195253A1 (en) * | 2001-08-14 | 2003-10-16 | Franz G. Andrew | Unadsorbed levothyroxine pharmaceutical compositions, methods of making and methods of administration |
US20030198672A1 (en) * | 2001-08-14 | 2003-10-23 | Franz G. Andrew | Levothyroxine compositions having unique triidothyronine plasma AUC properties |
US20030203967A1 (en) * | 2001-08-14 | 2003-10-30 | Franz G. Andrew | Levothyroxine compositions having unique Tmax properties |
US20030199587A1 (en) * | 2001-08-14 | 2003-10-23 | Franz G. Andrew | Levothyroxine compositions having unique Cmax properties |
US20030181524A1 (en) * | 2001-10-29 | 2003-09-25 | Franz G. Andrew | Levothyroxine compositions having unique triiodothyronine Tmax properties |
KR100514590B1 (ko) * | 2001-12-18 | 2005-09-14 | 주식회사 대웅 | 프라바스타틴나트륨 및 안정화제로서의 코폴리비돈을함유하는 약제 조성물 |
US20040101543A1 (en) * | 2002-03-22 | 2004-05-27 | John Liu | Nicotine-containing oral dosage form |
WO2004054568A1 (en) * | 2002-12-17 | 2004-07-01 | Abbott Gmbh & Co. Kg | Formulation comprising fenofibric acid, a physiologically acceptable salt or derivative thereof |
US20080051411A1 (en) * | 2002-12-17 | 2008-02-28 | Cink Russell D | Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof |
CA2509958A1 (en) * | 2003-02-03 | 2004-08-19 | Novartis Ag | Pharmaceutical formulation |
US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
US8377952B2 (en) * | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
GB2418854B (en) * | 2004-08-31 | 2009-12-23 | Euro Celtique Sa | Multiparticulates |
EP2140861A1 (en) * | 2008-06-30 | 2010-01-06 | Abbott GmbH & Co. KG | Pharmaceutical dosage form comprising polymeric carrier composition |
ES2511145T3 (es) * | 2010-10-14 | 2014-10-22 | Abbott Gmbh & Co. Kg | Formulación de dispersión sólida de curcuminoides |
BR112013023879B1 (pt) | 2011-03-21 | 2022-08-30 | Boehringer Ingelheim International Gmbh | Preparações sólidas que contém ambroxol, seu método de preparação, forma de dosagem farmacêutica e seus usos |
US9375033B2 (en) | 2014-02-14 | 2016-06-28 | R.J. Reynolds Tobacco Company | Tobacco-containing gel composition |
US20190217531A1 (en) * | 2016-04-06 | 2019-07-18 | Astellas Pharma Inc. | Fast-eluting three-dimensionally molded object, filament for fast-eluting three-dimensionally molded object, and material for fast-eluting three-dimensionally molded object |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3612211A1 (de) | 1986-04-11 | 1987-10-15 | Basf Ag | Kontinuierliches verfahren zum tablettieren |
DE3826946C1 (da) | 1988-08-09 | 1990-03-15 | A. Nattermann & Cie Gmbh, 5000 Koeln, De | |
DE69527711T2 (de) | 1994-06-14 | 2002-12-05 | Biovail Technologies Ltd., Chantilly | Verfahren und apparat zur herstellung von schnelllöslichen dosierungseinheiten und daraus erhältliches produkt |
-
1995
- 1995-09-29 DE DE19536394A patent/DE19536394A1/de not_active Withdrawn
-
1996
- 1996-09-26 TW TW085111773A patent/TW438599B/zh not_active IP Right Cessation
- 1996-09-27 ZA ZA9608130A patent/ZA968130B/xx unknown
- 1996-09-30 KR KR1019980702324A patent/KR19990063853A/ko not_active Application Discontinuation
- 1996-09-30 CZ CZ98959A patent/CZ95998A3/cs unknown
- 1996-09-30 JP JP51396597A patent/JP4041163B2/ja not_active Expired - Lifetime
- 1996-09-30 EP EP96934494A patent/EP0854707B1/de not_active Expired - Lifetime
- 1996-09-30 US US09/029,362 patent/US6187342B1/en not_active Expired - Lifetime
- 1996-09-30 CN CNB961972637A patent/CN1200694C/zh not_active Expired - Lifetime
- 1996-09-30 WO PCT/EP1996/004262 patent/WO1997012603A1/de not_active Application Discontinuation
- 1996-09-30 ES ES96934494T patent/ES2187678T3/es not_active Expired - Lifetime
- 1996-09-30 DK DK96934494T patent/DK0854707T3/da active
- 1996-09-30 IL IL12325096A patent/IL123250A/xx not_active IP Right Cessation
- 1996-09-30 DE DE59609923T patent/DE59609923D1/de not_active Expired - Lifetime
- 1996-09-30 RU RU98108536/14A patent/RU2197228C2/ru active
- 1996-09-30 BR BR9610799A patent/BR9610799A/pt active Search and Examination
- 1996-09-30 AU AU72828/96A patent/AU7282896A/en not_active Abandoned
- 1996-09-30 CA CA002230950A patent/CA2230950C/en not_active Expired - Lifetime
- 1996-09-30 HU HU9903384A patent/HUP9903384A3/hu unknown
- 1996-09-30 AT AT96934494T patent/ATE228355T1/de active
-
1998
- 1998-03-13 MX MX9801988A patent/MX9801988A/es not_active IP Right Cessation
- 1998-03-24 BG BG102346A patent/BG102346A/bg unknown
- 1998-03-27 NO NO981394A patent/NO981394L/no unknown
Also Published As
Publication number | Publication date |
---|---|
ATE228355T1 (de) | 2002-12-15 |
CN1200694C (zh) | 2005-05-11 |
CN1198094A (zh) | 1998-11-04 |
JP4041163B2 (ja) | 2008-01-30 |
BG102346A (bg) | 1998-10-30 |
IL123250A (en) | 2000-08-31 |
ES2187678T3 (es) | 2003-06-16 |
ZA968130B (en) | 1998-03-27 |
CA2230950A1 (en) | 1997-04-10 |
WO1997012603A1 (de) | 1997-04-10 |
EP0854707B1 (de) | 2002-11-27 |
CZ95998A3 (cs) | 1998-08-12 |
RU2197228C2 (ru) | 2003-01-27 |
TW438599B (en) | 2001-06-07 |
NO981394D0 (no) | 1998-03-27 |
HUP9903384A2 (hu) | 2000-10-28 |
NO981394L (no) | 1998-03-27 |
JPH11512729A (ja) | 1999-11-02 |
HUP9903384A3 (en) | 2001-04-28 |
DE19536394A1 (de) | 1997-04-03 |
EP0854707A1 (de) | 1998-07-29 |
MX9801988A (es) | 1998-08-30 |
DE59609923D1 (de) | 2003-01-09 |
CA2230950C (en) | 2007-12-04 |
BR9610799A (pt) | 1999-07-13 |
KR19990063853A (ko) | 1999-07-26 |
AU7282896A (en) | 1997-04-28 |
IL123250A0 (en) | 1998-09-24 |
US6187342B1 (en) | 2001-02-13 |
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