DK0827537T3 - Chromatin-regulator-gener - Google Patents
Chromatin-regulator-generInfo
- Publication number
- DK0827537T3 DK0827537T3 DK96914165T DK96914165T DK0827537T3 DK 0827537 T3 DK0827537 T3 DK 0827537T3 DK 96914165 T DK96914165 T DK 96914165T DK 96914165 T DK96914165 T DK 96914165T DK 0827537 T3 DK0827537 T3 DK 0827537T3
- Authority
- DK
- Denmark
- Prior art keywords
- regulator genes
- chromatin regulator
- genes
- chromatin
- deregulation
- Prior art date
Links
- 108010077544 Chromatin Proteins 0.000 title 1
- 108700005075 Regulator Genes Proteins 0.000 title 1
- 210000003483 chromatin Anatomy 0.000 title 1
- 230000003831 deregulation Effects 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 108700039010 SET domains Proteins 0.000 abstract 1
- 102000051614 SET domains Human genes 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19516776A DE19516776A1 (de) | 1995-05-10 | 1995-05-10 | Chromatin-Regulatorgene |
PCT/EP1996/001818 WO1996035784A2 (de) | 1995-05-10 | 1996-05-02 | Chromatin-regulatorgene |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0827537T3 true DK0827537T3 (da) | 2008-12-01 |
Family
ID=7761318
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96914165T DK0827537T3 (da) | 1995-05-10 | 1996-05-02 | Chromatin-regulator-gener |
Country Status (11)
Country | Link |
---|---|
US (2) | US6689583B1 (da) |
EP (1) | EP0827537B1 (da) |
JP (1) | JP4295824B2 (da) |
AT (1) | ATE404667T1 (da) |
CA (1) | CA2220442C (da) |
DE (2) | DE19516776A1 (da) |
DK (1) | DK0827537T3 (da) |
ES (1) | ES2313726T3 (da) |
MX (1) | MX9708401A (da) |
PT (1) | PT827537E (da) |
WO (1) | WO1996035784A2 (da) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19516776A1 (de) | 1995-05-10 | 1996-11-14 | Boehringer Ingelheim Int | Chromatin-Regulatorgene |
US6239327B1 (en) | 1998-04-16 | 2001-05-29 | Cold Spring Harbor Laboratory | Seed specific polycomb group gene and methods of use for same |
CA2366479A1 (en) * | 1999-03-11 | 2000-09-14 | Genesis Research And Development Corporation Ltd. | Compositions and methods for the modification of gene transcription |
US6555329B2 (en) * | 2000-06-09 | 2003-04-29 | Boehringer Ingelheim International Gmbh | Method for identifying compounds altering higher-order chromatin-dependent chromosome stability |
US20020039776A1 (en) | 2000-06-09 | 2002-04-04 | Thomas Jenuwein | Mammalian SUV39H2 proteins and isolated DNA molecules encoding them |
WO2002031745A1 (en) * | 2000-10-10 | 2002-04-18 | Genencor International, Inc. | Information rich libraries |
WO2003000715A1 (en) | 2001-06-22 | 2003-01-03 | Ceres, Inc. | Chimeric histone acetyltransferase polypeptides |
US20040053848A1 (en) * | 2001-08-23 | 2004-03-18 | Allis C. David | Antibodies specific for methylated lysines in histones |
WO2003055506A1 (fr) * | 2001-12-27 | 2003-07-10 | Takeda Chemical Industries, Ltd. | Medicaments pour la prevention et le traitement du cancer |
GB0228900D0 (en) * | 2002-12-11 | 2003-01-15 | Ml Lab Plc | Cancer Immunotherapy |
WO2004058969A1 (ja) * | 2002-12-24 | 2004-07-15 | Takeda Pharmaceutical Company Limited | がんの予防・治療剤 |
CN1914320A (zh) | 2003-12-03 | 2007-02-14 | 中外制药株式会社 | 利用哺乳类β肌动蛋白启动子的表达体系 |
JP2005170799A (ja) * | 2003-12-08 | 2005-06-30 | Univ Kurume | zesteホモログ2のエンハンサーのHLA−A24結合ペプチド |
JP5160885B2 (ja) * | 2004-06-01 | 2013-03-13 | ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル | 再構成ヒストンメチルトランスフェラーゼ複合体及びそのモジュレーターの識別方法 |
WO2007097494A1 (en) * | 2006-02-27 | 2007-08-30 | Imgen Co., Ltd. | De-differentiation of astrocytes into neural stem cell using bmi-1 |
US8574832B2 (en) | 2010-02-03 | 2013-11-05 | Massachusetts Institute Of Technology | Methods for preparing sequencing libraries |
US20130195843A1 (en) * | 2010-06-23 | 2013-08-01 | British Columbia Cancer Agency Branch | Biomarkers for Non-Hodgkin Lymphomas and Uses Thereof |
WO2011160206A1 (en) | 2010-06-23 | 2011-12-29 | Morin Ryan D | Biomarkers for non-hodgkin lymphomas and uses thereof |
US9175331B2 (en) * | 2010-09-10 | 2015-11-03 | Epizyme, Inc. | Inhibitors of human EZH2, and methods of use thereof |
KR102373074B1 (ko) | 2010-09-10 | 2022-03-11 | 에피자임, 인코포레이티드 | 인간 ezh2의 억제제 및 이의 사용 방법 |
WO2012050963A2 (en) | 2010-09-29 | 2012-04-19 | The General Hospital Corporation D/B/A Massachusetts General Hospital | Agents providing controls and standards for immuno-precipitation assays |
TWI598336B (zh) | 2011-04-13 | 2017-09-11 | 雅酶股份有限公司 | 經取代之苯化合物 |
JO3438B1 (ar) | 2011-04-13 | 2019-10-20 | Epizyme Inc | مركبات بنزين مستبدلة بأريل أو أريل غير متجانس |
RU2658911C2 (ru) | 2012-04-13 | 2018-06-26 | Эпизайм, Инк. | Солевая форма ингибитора гистон-метилтрансферазы ezh2 человека |
US10092572B2 (en) | 2012-10-15 | 2018-10-09 | Epizyme, Inc. | Substituted benzene compounds |
RU2015139054A (ru) | 2013-03-14 | 2017-04-19 | Дженентек, Инк. | Способы лечения рака и профилактики лекарственной резистентности рака |
CN103215352B (zh) * | 2013-03-29 | 2015-03-11 | 中国医学科学院血液病医院(血液学研究所) | 一种检测setd2基因突变的试剂盒 |
EA038869B1 (ru) | 2013-10-16 | 2021-10-29 | Эпизим, Инк. | Кристаллические формы гидрохлорида n-((4,6-диметил-2-оксо-1,2-дигидропиридин-3-ил)метил)-5-(этил(тетрагидро-2h-пиран-4-ил)амино)-4-метил-4'-(морфолинометил)-[1,1'-бифенил]-3-карбоксамида, фармацевтические композиции на их основе и способы их применения |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5486623A (en) | 1993-12-08 | 1996-01-23 | Prototek, Inc. | Cysteine protease inhibitors containing heterocyclic leaving groups |
DE19516776A1 (de) | 1995-05-10 | 1996-11-14 | Boehringer Ingelheim Int | Chromatin-Regulatorgene |
EP0956032A4 (en) | 1996-12-20 | 2002-09-04 | Univ Texas | PROTEINS AND COMPOSITIONS FOR MODULATING MITOSIS |
US6004933A (en) | 1997-04-25 | 1999-12-21 | Cortech Inc. | Cysteine protease inhibitors |
US5972608A (en) * | 1997-08-27 | 1999-10-26 | University Of Massachusetts | Assays and reagents for chromatin remodeling enzymes and their modulators |
EP1029547A1 (en) | 1999-02-15 | 2000-08-23 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Pharmaceutically active compounds and method for identifying same |
US20020039776A1 (en) * | 2000-06-09 | 2002-04-04 | Thomas Jenuwein | Mammalian SUV39H2 proteins and isolated DNA molecules encoding them |
US6555329B2 (en) * | 2000-06-09 | 2003-04-29 | Boehringer Ingelheim International Gmbh | Method for identifying compounds altering higher-order chromatin-dependent chromosome stability |
EP1227160A1 (en) | 2001-01-19 | 2002-07-31 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Compounds modulating sister chromatid separation and method for identifying same |
US20020164620A1 (en) * | 2001-01-19 | 2002-11-07 | Boehringer Ingelheim International Gmbh | Method for identifying compounds modulating sister chromatid separation |
KR100708794B1 (ko) * | 2001-05-04 | 2007-04-18 | 유니버시티 오브 플로리다 리서치 파운데이션, 아이엔씨. | 박테리아로부터 유래한 피루베이트 데카르복실라제(pdc) 유전자의 클로닝 및 서열분석, 및 그의 용도 |
-
1995
- 1995-05-10 DE DE19516776A patent/DE19516776A1/de not_active Withdrawn
-
1996
- 1996-05-02 MX MX9708401A patent/MX9708401A/es unknown
- 1996-05-02 PT PT96914165T patent/PT827537E/pt unknown
- 1996-05-02 EP EP96914165A patent/EP0827537B1/de not_active Expired - Lifetime
- 1996-05-02 ES ES96914165T patent/ES2313726T3/es not_active Expired - Lifetime
- 1996-05-02 WO PCT/EP1996/001818 patent/WO1996035784A2/de active IP Right Grant
- 1996-05-02 DE DE59611481T patent/DE59611481D1/de not_active Expired - Lifetime
- 1996-05-02 CA CA2220442A patent/CA2220442C/en not_active Expired - Lifetime
- 1996-05-02 JP JP53371596A patent/JP4295824B2/ja not_active Expired - Fee Related
- 1996-05-02 DK DK96914165T patent/DK0827537T3/da active
- 1996-05-02 AT AT96914165T patent/ATE404667T1/de active
-
2000
- 2000-06-09 US US09/589,892 patent/US6689583B1/en not_active Expired - Lifetime
-
2004
- 2004-02-09 US US10/773,302 patent/US7252968B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE59611481D1 (en) | 2008-09-25 |
CA2220442C (en) | 2011-07-12 |
PT827537E (pt) | 2008-10-09 |
ATE404667T1 (de) | 2008-08-15 |
US6689583B1 (en) | 2004-02-10 |
US20050089880A1 (en) | 2005-04-28 |
CA2220442A1 (en) | 1996-11-14 |
JP2001505402A (ja) | 2001-04-24 |
JP4295824B2 (ja) | 2009-07-15 |
DE19516776A1 (de) | 1996-11-14 |
WO1996035784A3 (de) | 1996-12-27 |
US7252968B2 (en) | 2007-08-07 |
EP0827537B1 (de) | 2008-08-13 |
ES2313726T3 (es) | 2009-03-01 |
MX9708401A (es) | 1998-02-28 |
EP0827537A2 (de) | 1998-03-11 |
WO1996035784A2 (de) | 1996-11-14 |
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