DK0806408T3 - Antivirale forbindelser - Google Patents

Antivirale forbindelser

Info

Publication number
DK0806408T3
DK0806408T3 DK97303020T DK97303020T DK0806408T3 DK 0806408 T3 DK0806408 T3 DK 0806408T3 DK 97303020 T DK97303020 T DK 97303020T DK 97303020 T DK97303020 T DK 97303020T DK 0806408 T3 DK0806408 T3 DK 0806408T3
Authority
DK
Denmark
Prior art keywords
virus
antiviral compounds
cell
mammal
inhibited
Prior art date
Application number
DK97303020T
Other languages
Danish (da)
English (en)
Inventor
William Joseph Hornback
John Edwin Munroe
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK0806408T3 publication Critical patent/DK0806408T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72Hydrazones
    • C07C251/84Hydrazones having doubly-bound carbon atoms of hydrazone groups being part of rings other than six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32Oximes
    • C07C251/34Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/44Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups being part of a ring other than a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/757Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26Phenanthrenes; Hydrogenated phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK97303020T 1996-05-06 1997-05-02 Antivirale forbindelser DK0806408T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1687996P 1996-05-06 1996-05-06

Publications (1)

Publication Number Publication Date
DK0806408T3 true DK0806408T3 (da) 2001-01-02

Family

ID=21779504

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97303020T DK0806408T3 (da) 1996-05-06 1997-05-02 Antivirale forbindelser

Country Status (13)

Country Link
US (1) US6103922A (de)
EP (1) EP0806408B1 (de)
JP (1) JP2000510468A (de)
AT (1) ATE198070T1 (de)
AU (1) AU2752297A (de)
CA (1) CA2253405A1 (de)
DE (1) DE69703672T2 (de)
DK (1) DK0806408T3 (de)
ES (1) ES2152630T3 (de)
GR (1) GR3035556T3 (de)
PT (1) PT806408E (de)
SI (1) SI0806408T1 (de)
WO (1) WO1997041822A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6127422A (en) * 1996-05-06 2000-10-03 Eli Lilly And Company Anti-viral method
ATE199538T1 (de) 1996-05-06 2001-03-15 Lilly Co Eli Antivirusverbindungen
AU2752597A (en) * 1996-05-06 1997-11-26 Eli Lilly And Company Anti-viral compounds
PT806408E (pt) * 1996-05-06 2001-04-30 Lilly Co Eli Compostos anti-virais
CA2253502A1 (en) * 1996-05-06 1997-11-13 Stephen Warren Kaldor Anti-viral compounds
US6156924A (en) * 1996-05-06 2000-12-05 Eli Lilly And Company Anti-viral compounds
EP0806203A3 (de) * 1996-05-06 1998-04-29 Eli Lilly And Company Antivirale Zubereitungen
US6103923A (en) * 1996-05-06 2000-08-15 Eli Lilly And Company Anti-viral compounds
US6096917A (en) * 1997-05-02 2000-08-01 Eli Lilly And Company Anti-viral compounds
US6175034B1 (en) 2000-04-10 2001-01-16 Eli Lilly And Company Anti-viral compounds
US6777645B2 (en) * 2001-03-29 2004-08-17 Gsi Lumonics Corporation High-speed, precision, laser-based method and system for processing material of one or more targets within a field
US7312031B1 (en) 2002-12-06 2007-12-25 The Salk Institute For Biological Studies Alpha-complementation viral fusion assay

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2750405A (en) * 1952-06-18 1956-06-12 Hercules Powder Co Ltd Hydroxydehydroabietic acid and esters thereof
US2744102A (en) * 1952-12-13 1956-05-01 Hercules Powder Co Ltd Acetoxydehydroabietic acid derivatives
US2744100A (en) * 1952-12-13 1956-05-01 Hercules Powder Co Ltd Bromodehydroabietic acid derivatives
US2759014A (en) * 1953-04-06 1956-08-14 Searle & Co Derivatives of 9-oxo-octahydrophenan-threne-1-carboxylic acid
US2703809A (en) * 1953-07-31 1955-03-08 Hercules Powder Co Ltd 7-acetyl-1, 2, 3, 4, 4alpha, 9, 10, 10alpha-octahydro-1, 4alpha-dimethyl-9-oxo-1-phenhrenecarboxylic acid and esters thereof
US2750407A (en) * 1953-07-31 1956-06-12 Hercules Powder Co Ltd Substituted phenanthrenecarboxylic acid and esters thereof
US2767162A (en) * 1953-11-23 1956-10-16 Searle & Co Glycolyl derivatives of 1, 12-dimethylpolyhydrophenanthrene-1-carboxylic acid esters
US2750382A (en) * 1953-12-03 1956-06-12 Searle & Co Basic esters of 1, 12-dimethyl-6-alkoxy-1, 2, 3, 4, 9, 10, 11, 12-octahydrophenanthrene-1-carboxylic acids
US2753357A (en) * 1954-11-26 1956-07-03 Searle & Co Lactones of 1, 12-dimethyl-6, 10-dihydroxy-9-oxo-1, 2, 3, 4, 9, 10, 11, 12-octahydrophenanthrene-1-carboxylic acid
US2862955A (en) * 1955-08-17 1958-12-02 Searle & Co Esters of hydroxyacyl-9-oxodehydroabietic acid
US2854474A (en) * 1956-07-19 1958-09-30 Searle & Co 1,12-dimethyl-6-hydroxy-7-acyl-9-oxo-1,2,3,4,9,10,11,12-cotahydrophenan-threne-1-carboxylic acids and derivatives thereof
US2947778A (en) * 1958-09-23 1960-08-02 Searle & Co 1, 12-dimethyl-6-hydroxy-7-aroyl-1, 2, 3, 4, 9, 10, 11, 12-octahydrophenanthrene-1-car-boxylic acids, ethers and esters thereof
US3014957A (en) * 1959-01-23 1961-12-26 G D Searle & Co Inc 6-(substituted benzoyl) dehydroabietonitriles and derivatives
US3038930A (en) * 1960-08-12 1962-06-12 Searle & Co 1, 2, 3, 4, 4a, 9, 10, 10a-octahydro-7-hydroxy-6-methoxy-1, 4a-dimethyl-phenanthrene-1-(carboxylic acid/methanol)and corresponding esters
US3668223A (en) * 1970-08-19 1972-06-06 Merck & Co Inc 2-oxo-3-benzoxepins
US4333941A (en) * 1975-12-22 1982-06-08 The Dow Chemical Company Inhibition of enveloped viruses with phenyl ketones
GB1574019A (en) * 1977-01-14 1980-09-03 Joullie International Sa Therapeutically useful 3,4,5-trimethoxybenzene derivatives
US5015644A (en) * 1987-06-02 1991-05-14 Warner-Lambert Company Antihyperlipidemic and antiatherosclerotic urea and carbamate compounds
US5180736A (en) * 1989-03-23 1993-01-19 Warner-Lambert Company Polycyclic amines useful as cerebrovascular agents
US5116865A (en) * 1990-09-05 1992-05-26 Peters Richard H 15,16-seco-19-nor progestins
IL102548A (en) * 1991-08-02 1998-08-16 Medivir Ab Use of painting derivatives in the preparation of drugs for VIH inhibition and treatment of SDIA and new compounds
NL1003010C2 (nl) * 1996-05-03 1997-11-06 Dsm Nv Werkwijze voor het omzetten van een geminaal gesubstitueerd cyclopentadieen.
DK0806409T3 (da) * 1996-05-06 2001-04-17 Lilly Co Eli Antivirale forbindelser
ES2159815T3 (es) * 1996-05-06 2001-10-16 Lilly Co Eli Compuestos antivirales.
PT806408E (pt) * 1996-05-06 2001-04-30 Lilly Co Eli Compostos anti-virais
AU2752597A (en) * 1996-05-06 1997-11-26 Eli Lilly And Company Anti-viral compounds
ATE199538T1 (de) * 1996-05-06 2001-03-15 Lilly Co Eli Antivirusverbindungen
EP0806203A3 (de) * 1996-05-06 1998-04-29 Eli Lilly And Company Antivirale Zubereitungen

Also Published As

Publication number Publication date
CA2253405A1 (en) 1997-11-13
US6103922A (en) 2000-08-15
PT806408E (pt) 2001-04-30
GR3035556T3 (en) 2001-06-29
WO1997041822A3 (en) 1998-05-14
DE69703672T2 (de) 2001-05-17
DE69703672D1 (de) 2001-01-18
WO1997041822A2 (en) 1997-11-13
ES2152630T3 (es) 2001-02-01
AU2752297A (en) 1997-11-26
EP0806408B1 (de) 2000-12-13
EP0806408A1 (de) 1997-11-12
JP2000510468A (ja) 2000-08-15
ATE198070T1 (de) 2000-12-15
SI0806408T1 (en) 2001-04-30

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